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List of works by Brijesh Kumar Singh

A clinician's guide to understanding resistance to thyroid hormone due to receptor mutations in the TRα and TRβ isoforms.

scientific article published on 15 September 2017

Alteration in mitochondrial thiol enhances calcium ion dependent membrane permeability transition and dysfunction in vitro: a cross-talk between mtThiol, Ca(2+), and ROS.

scientific article published on 12 July 2011

An integrative approach identified genes associated with drug response in gastric cancer.

scientific article

BH3-only protein BIM: An emerging target in chemotherapy

scientific article published on 23 September 2017

Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.

scientific article published on 18 February 2014

Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model.

scientific article published on 29 April 2017

Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging.

scientific article published on 26 February 2017

Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult Mice

scientific article published on 11 February 2016

Direct effects of thyroid hormones on hepatic lipid metabolism.

scientific article

Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance.

scientific article published on 29 January 2014

Estrogen-Related Receptor Alpha: An Under-Appreciated Potential Target for the Treatment of Metabolic Diseases

scientific article published on 28 February 2020

Glycyrrhizic acid modulates t-BHP induced apoptosis in primary rat hepatocytes

scientific article

Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition

scientific article

Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity

scientific article published on 17 September 2016

Hepatic Lipid Catabolism via PPARα-Lysosomal Crosstalk

scientific article published on 31 March 2020

Hepatic mitochondrial dysfunction is a feature of Glycogen Storage Disease Type Ia (GSDIa).

scientific article published on 20 March 2017

Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation

scientific article published on 08 December 2016

Increasing Dietary Medium-Chain Fatty Acid Ratio Mitigates High-fat Diet-Induced Non-Alcoholic Steatohepatitis by Regulating Autophagy

scientific article published on 25 October 2017

Involvement of mitochondria mediated pathways in hepatoprotection conferred by Fumaria parviflora Lam. extract against nimesulide induced apoptosis in vitro

scientific article published on 20 September 2009

Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells

scientific article

Natural terpenes prevent mitochondrial dysfunction, oxidative stress and release of apoptotic proteins during nimesulide-hepatotoxicity in rats

scientific article

Nimesulide aggravates redox imbalance and calcium dependent mitochondrial permeability transition leading to dysfunction in vitro.

scientific article published on 8 May 2010

Novel Transcriptional Mechanisms for Regulating Metabolism by Thyroid Hormone

scientific article

Reciprocal Crosstalk Between Autophagic and Endocrine Signaling in Metabolic Homeostasis

scientific article published on 30 November 2016

Resveratrol induces insulin gene expression in mouse pancreatic α-cells.

scientific article published on 13 December 2013

Role of thyroid hormone in hepatic gene regulation, chromatin remodeling, and autophagy.

scientific article published on 16 February 2017

Short chain fatty acids induce UCP2-mediated autophagy in hepatic cells.

scientific article

Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle.

scientific article published on 12 November 2015

Thyroid hormone (T) stimulates brown adipose tissue activation via mitochondrial biogenesis and MTOR-mediated mitophagy

scientific article published on 13 September 2018

Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling

scientific journal article

Thyroid hormone receptor and ERRα coordinately regulate mitochondrial fission, mitophagy, biogenesis, and function

scientific article published on 26 June 2018

Thyroid hormone regulation of hepatic lipid and carbohydrate metabolism

scientific article

β-Adrenergic agonist and antagonist regulation of autophagy in HepG2 cells, primary mouse hepatocytes, and mouse liver

scientific article