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List of works by Rudolf Uher

A familial risk enriched cohort as a platform for testing early interventions to prevent severe mental illness

scientific article

A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder

scientific article published on 17 April 2015

A genome-wide association study of a sustained pattern of antidepressant response

scientific article

A mega-analysis of genome-wide association studies for major depressive disorder

scientific article

ATP-binding cassette sub-family F member 1 (ABCF1) is identified as a putative therapeutic target of escitalopram in the inflammatory cytokine pathway

scientific article published on 29 May 2013

Absolute Measurements of Macrophage Migration Inhibitory Factor and Interleukin-1-β mRNA Levels Accurately Predict Treatment Response in Depressed Patients.

scientific article published on 12 May 2016

Adverse reactions to antidepressants

scientific article

Affective lability in offspring of parents with major depressive disorder, bipolar disorder and schizophrenia

scientific article published on 06 June 2019

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype

scientific article published on 8 December 2016

An examination of decision making in bulimia nervosa

article by Pei-Chi Liao et al published 13 April 2009 in Neuropsychology, Development and Cognition. Section A: Journal of Clinical and Experimental Neuropsychology

An inflammatory biomarker as a differential predictor of outcome of depression treatment with escitalopram and nortriptyline

scientific article

An investigation of decision making in anorexia nervosa using the Iowa Gambling Task and skin conductance measurements

scientific article published on 18 May 2007

Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables.

scientific article

Antidepressant effects of nortriptyline and escitalopram in the GENDEP study: is one better than the other?

scientific article published in April 2013

Antidepressant-dependent mRNA changes in mouse associated with hippocampal neurogenesis in a mouse model of depression

scientific article published on November 2012

Antidepressants, social adversity and outcome of depression in general practice.

scientific article published on 9 July 2009

Anxiety disorders and childhood maltreatment as predictors of outcome in bipolar disorder

scientific article published on 18 August 2017

Association between C-reactive protein (CRP) with depression symptom severity and specific depressive symptoms in major depression

scientific article published on 28 February 2017

Association between bipolar spectrum features and treatment outcomes in outpatients with major depressive disorder.

scientific article published on 06 December 2010

Association of Antidepressant Medication Use During Pregnancy With Intellectual Disability in Offspring

scientific article published on 12 July 2017

Association of Maternal Use of Folic Acid and Multivitamin Supplements in the Periods Before and During Pregnancy With the Risk of Autism Spectrum Disorder in Offspring

scientific article published on 3 January 2018

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

scholarly article by Miruna C. Barbu et al published July 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Association of a brain methylation site with clinical outcomes in depression does not replicate across populations

scientific article published in April 2015

Attention-deficit hyperactivity disorder and anxiety disorders as precursors of bipolar disorder onset in adulthood

scientific article published on 21 June 2018

Autism risk following antidepressant medication during pregnancy.

scientific article

Basic symptoms in offspring of parents with mood and psychotic disorders.

scientific article

Basing psychiatric classification on scientific foundation: Problems and prospects ⬇️

scientific article published on December 1, 2012

Biomarkers of treatment outcome in schizophrenia: Defining a benchmark for clinical significance

scientific article published on 20 June 2015

Biomarkers predicting treatment outcome in depression: what is clinically significant?

scientific article published on January 2012

Body weight as a predictor of antidepressant efficacy in the GENDEP project

scientific article published on 9 March 2009

Brain lesions and eating disorders

scientific article

Brain responses to body image stimuli but not food are altered in women with bulimia nervosa

scientific article

Brain structural signature of familial predisposition for bipolar disorder: replicable evidence for involvement of the right inferior frontal gyrus

scientific article published on 20 July 2012

CYP2C19 genotype predicts steady state escitalopram concentration in GENDEP.

scientific article published on 17 September 2011

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 2. Psychological Treatments.

scientific article published on 02 August 2016

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 3. Pharmacological Treatments

scientific article published on 02 August 2016

Candidate Genes Expression Profile Associated with Antidepressants Response in the GENDEP Study: Differentiating between Baseline ‘Predictors' and Longitudinal ‘Targets'.

scientific article published on 18 December 2012

Candidate genes expression profile associated with antidepressants response in the GENDEP study: differentiating between baseline 'predictors' and longitudinal 'targets'.

scientific article published on 19 September 2012

Cerebral processing of food-related stimuli: effects of fasting and gender

scientific article published on 30 January 2006

Changes in body weight during pharmacological treatment of depression

scientific article published on 18 August 2010

Childhood maltreatment and comorbid anxiety in people with bipolar disorder

scientific article published on 11 December 2015

Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression: a meta-analysis

scientific article published in February 2012

Classification issues and challenges in child and adolescent psychopathology ⬇️

scientific article published on December 1, 2012

Classification of feeding and eating disorders: review of evidence and proposals for ICD‐11 ⬇️

scientific article published on June 1, 2012

Clinical and genetic correlates of suicidal ideation during antidepressant treatment in a depressed outpatient sample

scientific article published on 01 March 2011

Combining clinical variables to optimize prediction of antidepressant treatment outcomes

scientific article published in April 2016

Contribution of common genetic variants to antidepressant response

scientific article

Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants

scientific article

Copy number variants and therapeutic response to antidepressant medication in major depressive disorder

scientific article published on 21 January 2014

Depression symptom dimensions as predictors of antidepressant treatment outcome: replicable evidence for interest-activity symptoms

scientific article published on 20 September 2011

Depressive disorder moderates the effect of the FTO gene on body mass index

article

Differential efficacy of escitalopram and nortriptyline on dimensional measures of depression

scientific article published in March 2009

Differential motivational responses to food and pleasurable cues in anorexia and bulimia nervosa: a startle reflex paradigm

scientific article published on 22 June 2006

Differential neural responses to food images in women with bulimia versus anorexia nervosa

scientific article

Disruptive mood dysregulation disorder in offspring of parents with depression and bipolar disorder

scientific article published on 6 April 2017

Dissecting the genetic heterogeneity of depression through age at onset

scientific article published on 22 August 2012

Do suicidal thoughts or behaviors recur during a second antidepressant treatment trial?

scientific article published on 18 September 2012

Early and delayed onset of response to antidepressants in individual trajectories of change during treatment of major depression: a secondary analysis of data from the Genome-Based Therapeutic Drugs for Depression (GENDEP) study

scientific article

Eating disorders, gene-environment interactions and epigenetics

scientific article

Effect of antidepressant switching between nortriptyline and escitalopram after a failed first antidepressant treatment among patients with major depressive disorder

scientific article published on 30 January 2019

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies

Effect of left prefrontal repetitive transcranial magnetic stimulation on food craving

scientific article published on 8 August 2005

Elevated pain threshold in eating disorders: physiological and psychological factors.

scientific article

Estimating the heritability of reporting stressful life events captured by common genetic variants

scientific article published on 14 December 2012

Etiology in psychiatry: embracing the reality of poly-gene-environmental causation of mental illness

scientific article

Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2008 British Association for Psychopharmacology guidelines.

scientific article published on 12 May 2015

Exploring the role of drug-metabolising enzymes in antidepressant side effects

scientific article published on 12 March 2015

Familiality and SNP heritability of age at onset and episodicity in major depressive disorder

scientific article published on 20 February 2015

Fecundity of patients with schizophrenia, autism, bipolar disorder, depression, anorexia nervosa, or substance abuse vs their unaffected siblings

scientific article

Forum: The case for gene-environment interactions in psychiatry

scientific article published in July 2008

Functional Neuroanatomy of Body Shape Perception in Healthy and Eating-Disordered Women

scientific article published on 08 August 2005

Functional neuroanatomy of body checking in people with anorexia nervosa

scientific article published on 6 June 2013

Functional polymorphism in the brain-derived neurotrophic factor gene interacts with stressful life events but not childhood maltreatment in the etiology of depression.

scientific article

Gene-environment interactions in common mental disorders: an update and strategy for a genome-wide search

scientific article published on 10 December 2013

Gene-environment interactions in severe mental illness

scientific article

Gene-environment interplay in the etiology of psychosis

scientific article published on 15 January 2018

Genes, Environment, and Individual Differences in Responding to Treatment for Depression ⬇️

scientific article published on May 1, 2011

Genetic differences in cytochrome P450 enzymes and antidepressant treatment response

scientific article published on 20 November 2013

Genetic predictors of antidepressant side effects: a grouped candidate gene approach in the Genome-Based Therapeutic Drugs for Depression (GENDEP) study

scientific article published on 10 January 2014

Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project.

scientific article published on 29 July 2009

Genetic predictors of response to antidepressants in the GENDEP project

scientific article

Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis

scientific article

Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study

scientific article

Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits

scientific article

Genetic susceptibility for bipolar disorder and response to antidepressants in major depressive disorder

scientific article

Genetic variation in the Major Histocompatibility Complex and association with depression

Gene–Environment Interaction in Major Depression and Antidepressant Treatment Response ⬇️

scientific article published on April 1, 2012

Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts

scientific article published on 13 March 2019

Genome-wide approaches to antidepressant treatment: working towards understanding and predicting response

scientific article published on 27 June 2012

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

scientific article published on 26 April 2018

Genome-wide association analysis accounting for environmental factors through propensity-score matching: application to stressful live events in major depressive disorder

scientific journal article

Genome-wide association analysis of copy number variation in recurrent depressive disorder.

scientific article

Genome-wide association study of co-occurring anxiety in major depression

scientific article

Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project

scientific article published on 28 September 2010

Genome-wide association study of major recurrent depression in the U.K. population

scientific article published in June 2010

Genome-wide association study of treatment-resistance in depression and meta-analysis of three independent samples

scientific article published on 23 November 2018

Genome-wide pharmacogenetics of antidepressant response in the GENDEP project

scientific article

Genomewide association scan of suicidal thoughts and behaviour in major depression

scientific article (publication date: 2011)

Genomics and the classification of mental illness: focus on broader categories

scientific article

Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression

scientific article

History of suicide attempts among patients with depression in the GENDEP project

scientific article published on 22 September 2009

Hot and cold executive functions in youth with psychotic symptoms.

scientific article published on 07 June 2017

I'm not as slim as that girl: neural bases of body shape self-comparison to media images

scientific article published on 2 June 2007

Increasing cognitive load reduces interference from masked appetitive and aversive but not neutral stimuli

scientific article

Insulin resistance and outcome in bipolar disorder

scientific article published on 16 October 2014

Insulin resistance, diabetes mellitus, and brain structure in bipolar disorders

scientific article

Integrative mouse and human mRNA studies using WGCNA nominates novel candidate genes involved in the pathogenesis of major depressive disorder.

scientific article published in December 2013

Interaction between childhood maltreatment on immunogenetic risk in depression: Discovery and replication in clinical case-control samples

scientific article

Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project.

scientific article published on 9 March 2010

Interaction between specific forms of childhood maltreatment and the serotonin transporter gene (5-HTT) in recurrent depressive disorder

scientific article published on 25 July 2012

Interaction between stress and the BDNF Val66Met polymorphism in depression: a systematic review and meta-analysis

scientific article

Interaction between the BDNF gene Val/66/Met polymorphism and morning cortisol levels as a predictor of depression in adult women

scientific article

Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals

scientific article

Investigation of blood mRNA biomarkers for suicidality in an independent sample

scientific article

It would not have happened to me at home: qualitative exploration of sojourns abroad and eating disorders in young Czech women

scientific article

Larger right inferior frontal gyrus volume and surface area in participants at genetic risk for bipolar disorders

scientific article published on 30 July 2018

Lifetime prevalence of anxiety disorders in people with bipolar disorder: a systematic review and meta-analysis

scientific article published on 23 June 2015

Like father like daughter: sex-specific parent-of-origin effects in the transmission of liability for psychotic symptoms to offspring

scientific article published on 29 August 2018

Long-term effects of depression treatment

scientific article published on 6 January 2016

Major depressive disorder in DSM-5: implications for clinical practice and research of changes from DSM-IV.

scientific article

Managing patients' information in a community mental health team

article

Medial prefrontal cortex activity associated with symptom provocation in eating disorders

scientific article published in July 2004

Melancholic, atypical and anxious depression subtypes and outcome of treatment with escitalopram and nortriptyline

scientific article published on 15 March 2011

MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes

scientific article

Moderation of antidepressant response by the serotonin transporter gene.

scientific article published in July 2009

Neural correlates of body dissatisfaction in anorexia nervosa

scientific article

Neurodevelopmental and genetic determinants of exposure to adversity among youth at risk for mental illness

scientific article published on 20 November 2019

Neuroprotective effect of lithium on hippocampal volumes in bipolar disorder independent of long-term treatment response

scientific article

Neuroticism mediates the effect of P2RX7 on outcomes of mood disorders

scientific article published on 23 May 2012

Neurotrophic factors in depression in response to treatment

scientific article published on 21 May 2015

Non-random dropout and the relative efficacy of escitalopram and nortriptyline in treating major depressive disorder

scientific article published on 06 July 2012

Non-steroidal anti-inflammatory drugs and efficacy of antidepressants in major depressive disorder

scientific article published on 6 March 2012

Obesity, dyslipidemia and brain age in first-episode psychosis.

scientific article published on 10 February 2018

Person-centered measurement-based care for depression

scientific article published on October 2016

Personality Pathology Among Individuals With a Lifetime History of Anorexia Nervosa

scholarly article by Joanna Holliday et al published August 2006 in Journal of Personality Disorders

Pharmacogenetics of antidepressant response: A polygenic approach

scientific article published on 31 January 2017

Pharmacoproteomic investigation into antidepressant response in two mouse inbred strains

scientific article

Phenotypic Association Analyses With Copy Number Variation in Recurrent Depressive Disorder

scientific article

Polygenic interactions with environmental adversity in the aetiology of major depressive disorder.

scientific article published on 3 November 2015

Poor decision making in male patients with anorexia nervosa

scientific article published on 9 August 2011

Predictors of response and drop-out during intensive dialectical behavior therapy

scientific article

Prevalence of current anxiety disorders in people with bipolar disorder during euthymia: a meta-analysis

scientific article

Probing the genome to understand suicide

scientific article published in December 2010

Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension

scientific article published on September 2009

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Provocation of symmetry/ordering symptoms in Anorexia nervosa: a functional neuroimaging study

scientific article published on 20 May 2014

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

RETRACTED: Epigenetic traces of childhood maltreatment in peripheral blood: a new strategy to explore gene-environment interactions

retracted scientific article published in January 2014

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rating Short-Term Psychodynamic Therapy for the Canadian Network for Mood and Anxiety Treatments Depression Guidelines

scientific article published on January 2017

Reactivity of affect and self-esteem during remission in bipolar affective disorder: an experimental investigation

scientific article published on 8 June 2011

Real-world digital implementation of the Psychosis Polyrisk Score (PPS): A pilot feasibility study

scientific article published on 24 April 2020

Recovery and chronicity in anorexia nervosa: brain activity associated with differential outcomes

scientific article

Relative impact of maternal depression and associated risk factors on offspring psychopathology.

scientific article published on 12 January 2012

Reliability of multimodal MRI brain measures in youth at risk for mental illness

scientific article published on 18 April 2020

Repetitive transcranial magnetic stimulation reduces cue-induced food craving in bulimic disorders

scientific article published on 8 January 2010

Replication of machine learning methods to predict treatment outcome with antidepressant medications in patients with major depressive disorder from STAR*D and CAN-BIND-1

scientific article published on 28 June 2021

Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels

scientific article

Response to Kunte et al.

scientific article published in February 2015

Retraction

scientific article published on 01 September 2014

Risk of mental illness in offspring of parents with schizophrenia, bipolar disorder, and major depressive disorder: a meta-analysis of family high-risk studies

scientific article published on 19 August 2013

Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis

scientific article

Screening young people for obsessive compulsive disorder

scientific article published in October 2007

Self-, parent-report and interview measures of obsessive–compulsive disorder in children and adolescents

scientific article published on 13 October 2007

Self-report and clinician-rated measures of depression severity: can one replace the other?

scientific article published on 29 August 2012

Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results

scientific article published on 24 March 2011

Serotonin transporter length polymorphism, childhood maltreatment, and chronic depression: a specific gene-environment interaction.

scientific article published on 27 July 2012

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

scientific article

Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: clinical description and the role of the 5-HTTLPR.

scientific article published on 9 March 2011

Specific anxiety disorders and subsequent risk for bipolar disorder: a nationwide study.

scientific article published on June 2016

Stability of symptoms across major depressive episodes in bipolar disorder

scientific article published on December 2009

Stimulant Medication and Psychotic Symptoms in Offspring of Parents With Mental Illness

scientific article published on 30 December 2015

Stressful life events and the brain-derived neurotrophic factor gene in bipolar disorder

scientific article

Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depression

scientific article published on 6 October 2011

Stressful life events, cognitive symptoms of depression and response to antidepressants in GENDEP.

scientific article published on 6 July 2010

Subliminal food images compromise superior working memory performance in women with restricting anorexia nervosa

scientific article published on 11 March 2012

Suicidal ideation during treatment of depression with escitalopram and nortriptyline in genome-based therapeutic drugs for depression (GENDEP): a clinical trial

scientific article

The Changing Understanding of the Genetic and Environmental Causes of Mental Illness ⬇️

scientific article published on February 1, 2013

The Effect of Parental Modeling on Child Pain Responses: The Role of Parent and Child Sex.

scientific article published on February 2017

The Everyday Feeling Questionnaire: the structure and validation of a measure of general psychological well-being and distress

scientific article

The Genetics of Mental Illness: A Guide for Parents and Adoption Professionals

article

The contribution of prenatal and postnatal maternal anxiety and depression to child maladjustment

scientific article published on 18 July 2011

The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder

scientific article

The genetics of affective disorder and suicide.

scientific article published on 11 May 2010

The genome-wide expression effects of escitalopram and its relationship to neurogenesis, hippocampal volume, and antidepressant response

scientific article

The impact of phenotypic and genetic heterogeneity on results of genome wide association studies of complex diseases

scientific article

The implications of gene-environment interactions in depression: will cause inform cure?

scientific article published on 05 August 2008

The inability to ignore: distractibility in women with restricting anorexia nervosa

scientific article published on 29 February 2008

The interaction between child maltreatment, adult stressful life events and the 5-HTTLPR in major depression

scientific article published on 22 April 2013

The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis

scientific article

The moderation by the serotonin transporter gene of environmental adversity in the etiology of depression: 2009 update

scientific article

The role of genetic variation in the causation of mental illness: an evolution-informed framework

scientific article published on 25 August 2009

The role of loss and danger events in symptom exacerbation in bipolar disorder

scientific article published on 4 August 2012

The truth about genetic variation in the serotonin transporter gene and response to stress and medication

scientific article published in June 2011

Therapygenetics: the 5HTTLPR and response to psychological therapy.

scientific article published on 25 October 2011

Thinking about eating food activates visual cortex with reduced bilateral cerebellar activation in females with anorexia nervosa: an fMRI study

scientific article

Trajectories of change in depression severity during treatment with antidepressants

scientific article published on 29 October 2009

Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk

scientific article published in December 2021

Transcriptomics and the mechanisms of antidepressant efficacy

scientific article published on 12 November 2015

Trends in hospital admissions for eating disorders in a country undergoing a socio-cultural transition, the Czech Republic 1981-2005.

scientific article published on 19 July 2009

Tumor necrosis factor and its targets in the inflammatory cytokine pathway are identified as putative transcriptomic biomarkers for escitalopram response

scientific article

Typology of clinical course in bipolar disorder based on 18-month naturalistic follow-up

scientific article published on 18 July 2012

Use of Socioeconomic Status in Health Research

scientific article published in The Journal of the American Medical Association

Variation in GNB3 predicts response and adverse reactions to antidepressants

scientific article published on 8 September 2010

Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression.

scientific article published on 7 August 2013

Why negative meta-analyses may be false?

scientific article published on 10 February 2013

Youth Experience Tracker Instrument: A self-report measure of developmental antecedents to severe mental illness

scientific article published on 23 June 2020

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