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List of works by Aleksandr Nozdrachev

5-Lipoxygenase inhibitor zileuton inhibits Ca(2+)-responses induced by glutoxim and molixan in macrophages.

scientific article published in July 2016

A mechanism of the hydrochloric acid reception in the ileum

scientific article published on January 1, 2003

A novel mouse model for assessment of male sexual function.

scientific article published in August 2007

A possible molecular mechanism for the interaction of defensin with the sensory neuron membrane

scientific article published in July 2002

A regulatory effect of amino acids in organotypic cultures of lymphoid tissues with various degrees of immunological maturity

scientific article published on 01 March 2003

Action of enkephalins on synaptic processes in the metasympathetic nervous system

scientific article published on December 1, 1984

Activity of foot skin mechanoreceptors and afferent nerve fibres in the adult rat sciatic nerve are altered after central axotomy of sensory neurons

scientific article published on 01 January 2000

Adrenosensitive neurons of the myenteric (Auerbach's) plexus

scientific article published on March 1, 1977

Afference in the sympathetic pathways of the stomach related to its motor-evacuatory activity

scientific article published on August 1, 1973

Afferent activity in sympathetic nerve fibers of the stomach and its secretory activity

scientific article published on 01 April 1976

Afferent activity in the renal nerves of awake dogs treated with diuretics

scientific article published on November 1, 1975

Afferent activity of gastric nerves and its secretory activity following histamine administration

scientific article published on 01 September 1978

Afferent discharges in the vegal and sympathetic pathways of the stomach after the administration of digestive tract hormones

scientific article published on 01 December 1977

Afferent innervation of the trachea during postnatal development

scientific article published on 01 June 2005

Afferent reactions in the gastric branches of the vagus nerve and the developing secretory process

scientific article published on 01 September 1975

Age-dependent changes of electrophysiologic characteristics of the stellate ganglion conducting pathways in kittens

scientific article published on 01 September 2000

Age-dependent changes of neurochemical properties of sensory neurons

scientific article published in January 2013

Age-related characteristics of the neurotransmitter composition of neurons in the stellate ganglion

scientific article published on 01 May 2007

Amitriptyline Attenuates Ca2+ Responses Induced by Glutoxim and Molixan in Macrophages

scientific article published on 01 July 2018

An endogenous sensitizer of β adrenergic receptors and its analogs attenuate the inhibition of β adrenergic receptors by propranolol and atenolol in the rat myocardium

scientific article published on 01 May 2014

An endogenous sensitizer of β-adrenergic receptors and its analogs in the experiments with rat myometrium reduce the β-adrenoblocking effect of obzidan.

scientific article published on November 2010

Analysis of Differences between Physiological and Pathological Tremor of Human Fingers

scientific article published on October 1, 2010

Analysis of the effect of methylene blue on different links in the synaptic transmission of autonomic ganglia

scientific article published on November 1, 1976

Antinociceptive effect of the agonist of 5-HT1A receptors buspirone in the model of abdominal pain in dogs

scientific article published in March 2017

Assessment of beta-adrenergic reactivity of erythrocytes by their sedimentation rate in the presence of adrenergic agents

scientific article published on 01 February 1998

Asymmetry of peripheral effects of unilateral intranasal administration of oxytocin to male white rats

scientific article published on 01 May 1995

Blockers of monoamine transporters influence high dopamine concentration uptake in rat brain slices.

scientific article published in March 2008

Calbindin-D28k immunoreactivity in sympathetic ganglionic neurons during development

scientific article published on 05 January 2012

Calcium channel blockers inhibit the hyperglycemic effect of calcitonin

scientific article published on 01 March 2012

Cardiovascular manifestations of acute nitrite intoxication in laboratory rats

scientific article published on 01 September 2011

Characteristics of structural and functional organization of the rat pineal gland depending on age

scientific article published on 01 August 1997

Characteristics of the responses of smooth muscles of the uterus, coronary artery, and trachea to ozone and the ability of beta-adrenergic receptor sensitizers to decrease its beta-adrenergic blocking effect

scientific article published on 01 May 2003

Circuits and Projections of Cat Stellate Ganglion

scientific article published on March 1, 2003

Comenic acid decreases the impulse frequency of the nociceptive neuron membrane.

scientific article published on 12 July 2015

Critical periods of the dopaminergic system formation in rat brain.

scientific article published in September 2002

Cyclooxygenase and lipoxygenase inhibitors modulate the Glutoxim and Molixan effects on the intracellular Ca²⁺ concentration in macrophages.

scientific article

Development of Calbindin- and Calretinin-Immunopositive Neurons in the Enteric Ganglia of Rats.

scientific article published on 22 December 2016

Development of neuropeptide Y-containing neurons in sympathetic ganglia of rats

scientific article published on 07 September 2012

Development of neuropeptide Y-mediated heart innervation in rats.

scientific article published on 11 November 2015

Development of non-catecholaminergic sympathetic neurons in para- and prevertebral ganglia of cats

scientific article published on 6 December 2014

Development of the evoked potentials in the thalamus and cerebral cortex after stimulation of the stellate ganglion afferents in kittens.

scientific article published in October 2001

Developmental changes of neurotransmitter properties in sympathetic neurons

scientific article published in January 2017

Developmental changes of neurotransmitter properties in sympathetic neurons

scientific article published in January 2016

Does defensin NP-1 influence the excitability of the primary afferent neurons of the guinea pig small intestine?

scientific article published in March 2005

Effect of arginine and its metabolites on the rat myocardium in an organotypic tissue culture

scientific article published in July 2007

Effect of chemical desympathization on afferent neurocytes and the neuromuscular synapse

scientific article published on 01 August 1995

Effect of cholinergic substances on electrical processes in a ganglion of the enteric nervous system

scientific article published on 01 November 1978

Effect of disulfide-containing compounds on the Na+ transport in the frog skin.

scientific article published in July 2008

Effect of human blood serum on M-cholinoreactivity of rat stomach smooth muscles

scientific article published on 01 May 2007

Effect of methylene blue on transmission of excitation at peripheral autonomic synapses

scientific article published on September 1, 1976

Effect of physical training on blood level of endogenous modulators of beta-adreno- and m-cholinoreactivity in patients with a history of myocardial infarction

scientific article published on 01 July 2003

Effect of tetrapeptide cortagen on regeneration of sciatic nerve

scientific article published on 01 December 2000

Effects of endogenous modulators of beta-adrenergic and cholinergic receptors on heart rate variability.

scientific article published in January 2004

Effects of intranasal administration of epitalon on neuron activity in the rat neocortex.

scientific article published in November 2007

Effects of intranasal administration of pineal-gland peptides on aggressive-defensive behavior of unilaterally adrenalectomized rats

scientific article published on 01 January 2000

Effects of oral immunization with ovalbumin and pineal peptides on the locomotor activity in rats.

scientific article published in May 2001

Effects of pineal-gland peptides on the electric activity of pinealocytes in rats.

scientific article published in July 2002

Effects of stimulation of the frontoparietal cortex and parafascicular nucleus on locomotion in rats.

scientific article

Effects of the vagus nerve stimulation on amygdalohypothalamic and amygdalobulbular influences.

scientific article published on September 2010

Endogenous Sensitizer of Beta-Adrenergic Receptors (ESBAR) as a Component of Humoral Links Element of Autonomic Nervous System and Its Analogs (Review).

scientific article published in October 2016

Epiphyseal peptides influence antibody formation in Peyer's glands of immunized rats

scientific article published on 01 March 2000

Epoxygenase Inhibitors Attenuate the Stimulatory Effect of Glutoxim on Na+ Transport in Frog Skin

scientific article published on 01 May 2018

Expression of Menkes AtPase and Wilson ATPpase in different regions of the adult rat brain.

scientific article published in March 2005

Expression of Pattern Recognition Receptors by Nociceptive Metasympathetic Neurons

scientific article published on 19 June 2015

Expression of toll-like receptors 4 in nerve plexuses of the rat duodenum, jejunum, and colon

scientific article published on 01 July 2012

Extracellular recording of neuronal activity of the cat heart ganglia

scientific article published on 01 July 1982

Extrahypothalamic corticoliberin receptors regulate the reinforcing effects of self-stimulation.

scientific article published in January 2006

Features of Parkinsonian and essential tremor of the human hand

scientific article published in May 2016

Gastric related neurons in the rat medial vestibular nucleus

scientific article published on June 26, 1998

Hormones of the pituitary-adrenal system in the mechanisms of unconditioned and conditioned reflex reinforcement.

scientific article published in September 2005

How is bursting mode maintained under the action of exo- and endogenous factors?

scientific article published on 01 September 2001

Immunohistochemical study of GABa- and substance P-immunoreactive structures in cat stellate ganglia

scientific article published on 01 July 1994

Inhibitors of the cyclooxygenase oxidation pathway of arachidonic acid suppress the stimulating effect of glutoxim on Na(+) transport in frog skin

scientific article published on 01 July 2013

Interactions of cytokines and their components in nervous and lymphoid tissue cultures.

scientific article

Involvement of actin filaments in the effect of the oxidized glutathione and drug glutoxim on the intracellular Ca(2+) concentration in macrophages

scientific article published on 01 January 2011

Involvement of microtubules in the effects of glutoxim and molixan on the intracellular concentration of Ca(2+) in macrophages.

scientific article published in July 2013

Involvement of microtubules in the glutoxim regulation of Na(+) transport in the frog skin

scientific article published on 01 July 2012

Involvement of phosphatidylinositol kinases in the effect of oxidized glutathione and drug glutoxim on Na+ transport in frog skin.

scientific article published in September 2009

Involvement of small G proteins and vesicle traffic in the glutoxim and molixan effects on the intracellular Ca(2+) concentration in macrophages

scientific article published on 01 July 2014

Involvement of small intestine interoceptors in the response to endotoxins.

scientific article

Involvement of the Arp2/3 complex and WASP proteins in the effect of glutoxim and molixan on intracellular Ca(2+) concentration in macrophages.

scientific article

Lipoxygenases modulate the effect of glutoxim on Na+ transport in the frog skin epithelium.

scientific article published on May 2017

Liver glucose-6-phosphatase activity and blood fatty acid level in rats with insulin-induced hypoglycemia

scientific article published on 01 September 2008

Location of pattern-recognizing and vanilloid receptors in the nerve plexuses of the rat intestine

scientific article published on 01 September 2013

Low-molecular-weight components of the metabolome control the proliferative activity in cellular and bacterial cultures.

scientific article

Mechanism of increasing the rate of agglutination of human erythrocytes under the influence of adrenaline and its relation to eryptosis

scientific article published on 01 July 2013

Mechanisms of hyperglycemic effect of calcitonin

scientific article published on 01 January 2011

Metabotropic glutamate receptors as targets of neuromodulatory influence of nitric oxide.

scientific article published in July 2016

Metformin inhibits development of colon malignant tumors induced by 1,2-dimethylhydrazine in rats

scientific article published on 01 May 2016

Metformin prevents hormonal and metabolic disturbances and 1,2-dimethylhydrazine-induced colon carcinogenesis in non-diabetic rats.

scientific article published on February 2017

Method for detecting quantitative differences in the parameters of involuntary effort fluctuations in healthy volunteers and patients with Parkinson's syndrome.

scientific article published in October 2008

Methyl-β-cyclodextrin inhibits Ca2+-responses induced by glutoxim and molixan in macrophages.

scientific article published in November 2016

Methyl-β-cyclodextrin modulates thapsigargin-induced store-dependent Ca2+ entry in macrophages.

scientific article published in March 2017

Modulating and protective effects of thymic peptides in lymphoid tissue culture.

scientific article published in July 2001

Modulating effect of microflora metabolites of the human and animals on lymphoid tissue culture.

scientific article published in September 2009

Molecular mechanism of modulation of nociceptive neuron membrane excitability by a tripeptide

scientific article published on 31 March 2016

Morphological features of neurons innervating different viscera in the cat stellate ganglion in postnatal ontogenesis

scientific article published on 01 November 2000

Myenteric plexus. Basic principles for modeling neuronal organization

scientific article published on 01 August 1981

NO-dependent mechanisms of amygdalocortical influence.

scientific article published in July 2008

Neurochemical Features of Metasympathetic System Ganglia in the Course of Ontogenesis

scholarly article

Neurochemical organization of the brain reinforcing systems

scientific article published in August 2000

Neurochemical properties of sensory neurons in the development

scientific article published on July 2013

Neuroleptic Chlorpromazine Modulates Ca2+ Responses in Macrophages

scientific article published on 01 January 2020

Neuronal activity of submucosal plexus of pyloric and ileocecal sphincteric regions of the cat gastrointestinal tract

scientific article published on 01 June 1981

Neuronal electrical activity in the submucosal plexus of the cat small intestine

scientific article published on 01 February 1981

Neurons of the ventral horns of the spinal cord participate in visceral innervation during early postnatal ontogeny

scientific article published on 01 July 2001

Nitric oxide regulates the chemoattractant activity of defensin HNP-1 in the blood

scientific article published on 13 March 2015

Nonlinear dynamics of involuntary shaking of the human hand under motor dysfunction

scientific article published on March 2015

Participation of the dopaminergic brain system in effects of glucocorticoid hormones

scientific article published in July 2001

Parvalbumin-Containing Enteric Metasympathetic Neurons in Postnatal Ontogeny

scientific article published in 2020

Perception of secretory processes by the receptor apparatus of the gastric mucosa

scientific article published on January 1, 1975

Phospholipase A2 Inhibitors Modulate the Effect of Trifluoperazine on the Intracellular Ca2+ Concentration in Macrophages.

scientific article published in January 2018

Phospholipase A2 inhibitors modulate the effects of glutoxim and molixan on the intracellular Ca(2+) level in macrophages.

scientific article published in January 2015

Physiological characteristics of endogenous sensitizer of beta-adrenergic receptors (ESBAR) and its putative components

scientific article published on 01 September 2004

Physiological characteristics of myocytes of the human umbilical arteries and vein and the effect of umbilical blood serum on them.

scientific article published in January 2003

Possible involvement of phosphatidylinositol kinases in the effect of the oxidized glutathione and glutoxim on the intracellular Ca2+ concentration in macrophages.

scientific article published in September 2008

Possible mechanism of bursting suppression in nociceptive neurons

scientific article

Possible role of catalase in the adaptation to diving in semiaquatic rodents Ondatra zibethica

scientific article published in January 2002

Principles of signal coding by the discharge pattern of a neuron population.

scientific article

Protective effect of amino acids and oligopeptides in combination with a cytostatic agent on lymphoid tissue culture.

scientific article published in January 2009

Pyrazoline reception: a possible role of opioid receptors of sensory neurons

scientific article published in January 2000

Recovery of mechanoreception at the initial stage of regeneration of injured sciatic nerve in rats in conditions of central axotomy of sensory neurons

scientific article published on 01 October 2004

Regulatory effects of essential and nonessential amino acids on organotypic cultures of spleen and liver tissues

scientific article published in November 2003

Reinforcement effect of glucocorticoid hormones.

scientific article published in July 2000

Respiratory reactions and afferent activity during various actions on the receptors of a transplanted reinnervated kidney

scientific article published on 01 April 1974

Rhythmic electrical activity in branches of the stellate ganglion in the cat during postnatal ontogenesis

scientific article published on 01 June 2007

Role of the dopaminergic system of the brain in the effects of glucocorticoid hormones.

scientific article published in March 2003

Sensory connection of the cat stellate ganglion

scientific article published on 01 February 1998

Serotonergic mechanisms of formation of emotional behavior of rats in ontogeny

scientific article published in November 2003

Sigma-1 Receptor Agonist Amitriptyline Inhibits Store-Dependent Ca2+ Entry in Macrophages

scientific article published on 01 September 2019

Sigma-1 Receptor Antagonist Haloperidol Attenuates Store-Dependent Ca2+ Entry in Macrophages

scientific article published on 01 May 2018

Sigma-1 Receptor Antagonists Haloperidol and Chlorpromazine Modulate the Effect of Glutoxim on Na+ Transport in Frog Skin

scientific article published on 22 April 2019

Sigma-1 receptor antagonist haloperidol attenuates Ca2+ responses induced by glutoxim and molixan in macrophages

scientific article published in January 2017

Social isolation syndrome in rats.

scientific article published in March 2004

Sodium nitrite influences metabolic conversions of nitric oxide in tissues of the right and left ventricles of the rat heart

scientific article published on 01 May 2013

Stimulation of cell proliferation and apoptosis in the presence of amino acids in organotypic culture of tissues of different degree of maturity

scientific article published in January 2006

Studies of chemoreceptor perception in mollusks.

scientific article published in March 2001

Sympathetic Innervation of Stomach in Postnatal Development

scientific article published on 01 November 2018

The 12 Sechenov years (1876-1888) of Petersburg University

scientific article published on November 1, 1991

The 5HT4 receptor agonist prucalopride suppresses abdominal nociception

scientific article published on 05 May 2015

The Effects of Weak Static Magnetic Field on the Development of Organotypic Tissue Culture in Rats

scientific article published on 01 July 2018

The changes in the nervous structures under the chemical sympathectomy with guanethidine

scientific article published on 01 December 1998

The defensin receptor: a possible mechanism responsible for reduced excitability of the neuronal sensory membrane.

scientific article published in November 2000

The delayed effect of cortagen on the restoration of injured nerve function

scientific article published on 01 May 2002

The distribution pattern of galactose-specific lectin receptors in sensory ganglia of mature white rats.

scientific article published in September 2002

The dynamics of stimulating and inhibiting influence on organoid cultures of nervous and lymphoid tissues

scientific article published on 01 September 2001

The effect of amino acid combinations on the development of tissues of different origins in an organotypic culture

scientific article published on 01 September 2011

The effect of chemical sympathectomy on the conducting system of the white rat vagus nerve.

scientific article published in July 2002

The effect of chlorpromazine on intracellular Ca2+ concentration in macrophages

scientific article published in May 2017

The effect of hexapeptide Glutoxim on tissue explant development in organoid cultures

scientific article published on 01 September 2004

The effect of histidine on the contractility and adrenoreactivity of the myocardium of nonpregnant and pregnant rats

scientific article published on 13 March 2015

The effect of the intraventricular administration of oxytocin on the functional activity of the epiphysis, adrenals and gonads and on the behavior of rats

scientific article published on 01 February 1994

The effects of epiphyseal peptides on the release of immunoglobulins in Peyer's patches in rats in vitro.

scientific article published on November 2003

The influence of sodium nitrite on the locomotor functions of white blood cells.

scientific article published in July 2009

The inhibitors of Arp2/3 complex and WASP proteins modulate the effect of glutoxim on Na(+) transport in frog skin

scientific article

The mechanisms regulating the activity of the longitudinal layer of the intestinal smooth muscle in the Dolly Varden trout

scientific article published on 01 August 1991

The possible involvement of calcium ions in the regulatory effect of oxidized glutathione on macrophages

scientific article published on 01 January 2007

The reactions of the tracheal smooth muscle to histamine

scientific article published on 01 July 1997

The role of defensin NP-1 in restoring the functions of an injured nerve trunk

scientific article published on 01 March 2006

The role of defensins in the excitability of the peripheral vestibular system in the frog: evidence for the presence of communication between the immune and nervous systems

scientific article published on 24 May 2007

The role of nitric oxide in regulation of leukocyte migration into the heart tissue in vitro

scientific article published on 01 November 2015

The role of the actin cytoskeleton in the regulation of Na+ transport by phosphatidylinositol kinases in the frog skin

scientific article published on 01 September 2006

The role of the key enzymes of the phosphoinositide signaling pathway in the effect of oxidized glutathione and glutoxim on intracellular Ca2+ concentration in macrophages.

scientific article published in September 2009

The role of tyrosine kinases and tyrosine phosphatases in the effect of glutoxim and oxidized glutathione on the intracellular Ca2+ concentration in macrophages.

scientific article

The stimulatory effect of small doses of inhibitors in organotypic culture of nervous and lymphoid tissues

scientific article

The structure of rat pinealocytes in stress and after unilateral intranasal administrations of oxytocin

scientific article published on 01 August 1997

The system of endogenous modulators involved in the control of functioning of peripheral autonomic nervous structures

scientific article published on 01 March 2002

Topographical location and connection of nerve elements at margins of Peyer's patches in rat small intestine

scientific article published on 01 October 1997

Trifluoperazine Attenuates Store-Dependent Ca2+ Entry in Macrophages.

scientific article published in January 2018

Uteroactive, beta-adrenomodulating, and M-cholinomodulating properties of the human umbilical blood serum

scientific article published on 01 January 2003

[AChE-positive neurons in the mammalian stellate ganglion]

scientific article published on 01 October 1995

[Activity of a series of amino acids as potential sensitizers of smooth muscle beta-receptors]

scientific article published on 01 November 1998

[Adrenomodulating effects of human blood, cerebrospinal fluid, urine, saliva, and amniotic fluid]

scientific article published on 01 January 1997

[Age-development changes of the sympathetic innervation of the rat stomach.]

scientific article published on 01 January 2018

[Age-related expression of calcium-binding proteins in autonomic ganglionic neurons]

[Comparative characteristics of electroretinograms caused by light and x-ray stimulation in various adaptation periods]

scientific article published on 01 January 1994

[Contractile activity of fibroblasts from human fetal membranes under in vitro conditions]

scientific article published on 01 October 1999

[Effect of nitrite-induced methemoglobinemia on the kinetics of blood deoxygenation]

scientific article published on 01 March 2006

[Effects of acetylcholine and histamine on leukocyte and neutrophil numbers in the endometrium of rats in various phases of the estrous cycle (by imprints)]

scientific article published on 01 December 2000

[Electrical activity and circulatory effects of nitrite in the rat cerebrum]

scientific article published on 01 March 2015

[Endogenous defensin antibiotics as tentative regulators of sodium channels in spinal ganglion neurons]

scientific article published on 01 August 1997

[Functional changes in the mucosa of the small intestine of sturgeons in toxic exposures]

scientific article published on 01 April 1993

[Hypoxic factors influence on chronotropic heart reactions of ondatra Ondatra zibethicus in free behavior]

scientific article published on 01 July 2006

[Increase in beta-adrenoreactivity of coronary arteries exposed to blood serum]

scientific article published on 01 December 1996

[Mediators of synaptic transmission in ganglia of the tracheal plexus]

scientific article published on 01 March 1995

[Melanostatin analog alaptide is a functional marker of social isolation state in rats]

scientific article published on 01 September 1999

[Metasympathetic system of the rat uterus--initial inputs and intraorganic architecture of nerve connection]

scientific article published on 01 July 1999

[Myocardial electrogenesis in laboratory rats under conditions of acute nitrite intoxication]

scientific article published on 01 March 2010

[Pinealocyte functioning in stress during daytime in rats]

scientific article published on 01 August 2000

[Projections of the gastrointestinal tract organs on afferent ganglions of the vagus nerve in rats]

scientific article published on 01 November 2003

[Putative molecular mechanism of defensin interaction with the membrane of the sensory neuron]

scientific article published on 01 November 2000

[Rhythmic activity of neurons of the tracheal plexus]

scientific article published on 01 November 1994

[Rhythmical electrical activity in the cat stellate ganglion during postnatal ontogenesis]

scientific article published on 01 March 2006

[Role of inorganic nitrite and nitric oxide in the function of cardiovascular system]

scientific article published on 01 March 2014

[Seasonal changes in adrenoreactivity and a modification in the fractional phospholipid composition of the frog bladder]

scientific article published on 01 September 1994

[The Analysis of Changes in EEG Patterns in Response to Transmittent Photic Stimulation in Different Disorders of Central Nervous System].

scientific article published in May 2015

[The action of adrenergic substances on the smooth muscle of the rat trachea]

scientific article published on 01 November 1993

[The age specifics of the neurotransmitter composition of the stellate ganglion neurons]

scientific article published on 01 February 2006

[The importance of metasympathetic nervous structures in the reactions of the smooth-muscle tracheal wall in sensitized rats]

scientific article published on 01 March 1993

[The influence of pineal peptides on in vitro immunoglobulin secretion by Peyer's patches in rats]

scientific article published on 01 July 2002

[The lateralization effect of oxytocin on the functional activity of paired visceral organs in rats]

scientific article published on 01 October 1995

[The leading physiologists of the beginning of the 20th century]

scientific article published on 01 April 1996

[The local reflex responses of rat tracheal smooth muscle]

scientific article published on 01 July 1996

[The mechanisms of serotonin participation in the smooth-muscle reactions of the trachea]

scientific article published on 01 August 1996

[The metasympathetic innervation of the lymphoid follicles of Peyer's patches in the rat small intestine]

scientific article published on 01 July 1996

[The metasympathetic mechanisms supporting the constancy and stability of the internal environment in vertebrates]

scientific article published on 01 September 1994

[The morphology and reactive changes in neural structures during chemical sympathectomy]

scientific article published on 01 October 1995

[The structure of the initial inputs into the metasympathetic nervous system of the rat uterus]

scientific article published on 01 January 1999