List of works by Henry Leonidas Gómez

A Phase II Randomized Study of Lapatinib Combined With Capecitabine, Vinorelbine, or Gemcitabine in Patients With HER2-Positive Metastatic Breast Cancer With Progression After a Taxane (Latin American Cooperative Oncology Group 0801 Study).

scientific article

A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.

scientific article

A phase 3 tRial comparing capecitabinE in combination with SorafenIb or pLacebo for treatment of locally advanced or metastatIc HER2-Negative breast CancEr (the RESILIENCE study): study protocol for a randomized controlled trial.

scientific article published on 22 July 2013

A phase II study of a novel gemcitabine plus cisplatin regimen administered every three weeks for advanced non-small-cell lung cancer.

scientific article

A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma.

scientific article published on 28 November 2011

A randomized and open-label trial evaluating the addition of pazopanib to lapatinib as first-line therapy in patients with HER2-positive advanced breast cancer

scientific article published on 3 January 2013

A randomized phase II study of lapatinib + pazopanib versus lapatinib in patients with HER2+ inflammatory breast cancer.

scientific article published on 13 December 2012

Absolute Benefit of Adjuvant Endocrine Therapies for Premenopausal Women With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer: TEXT and SOFT Trials.

scientific article published on 04 April 2016

Addition of amifostine to the CHOP regimen in elderly patients with aggressive non-Hodgkin lymphoma: a phase II trial showing reduction in toxicity without altering long-term survival.

scientific article published in January 2012

Adjuvant Lapatinib and Trastuzumab for Early Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Results From the Randomized Phase III Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization Trial

scientific article

Advanced Extramammary Paget's Disease of the Groin, Penis, and Scrotum.

scientific article published on 6 July 2014

Analysis of dermatologic events in patients with cancer treated with lapatinib.

scientific article published on 04 July 2008

Attitudes of young patients with breast cancer toward fertility loss related to adjuvant systemic therapies. EORTC study 10002 BIG 3-98.

scientific article published on 29 August 2013

BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors.

scientific article published on 22 July 2011

Behaviour of breast cancer molecular subtypes through tumour progression

scientific article published on 01 June 2012

Breast cancer classification according to immunohistochemistry markers: subtypes and association with clinicopathologic variables in a peruvian hospital database.

scientific article published on August 2010

Breast cancer in young women in Latin America: an unmet, growing burden

scientific article published on 01 January 2013

Breast cancer in young women in Latin America: an unmet, growing burden.

scientific article

Clinical benefit of lapatinib-based therapy in patients with human epidermal growth factor receptor 2-positive breast tumors coexpressing the truncated p95HER2 receptor.

scientific article published on 20 April 2010

Determination of oestrogen-receptor status and ERBB2 status of breast carcinoma: a gene-expression profiling study

scientific article published on 01 March 2007

Efficacy and safety of lapatinib as first-line therapy for ErbB2-amplified locally advanced or metastatic breast cancer

scientific article published on 5 May 2008

Efficacy of Neoadjuvant Carboplatin plus Docetaxel in Triple-Negative Breast Cancer: Combined Analysis of Two Cohorts.

scientific article published on 14 June 2016

Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor-positive breast cancer

scientific article published on 07 January 2014

Evaluation of a 30-gene paclitaxel, fluorouracil, doxorubicin, and cyclophosphamide chemotherapy response predictor in a multicenter randomized trial in breast cancer.

scientific article

Exploring disparities in incidence and mortality rates of breast and gynecologic cancers according to the Human Development Index in the Pan-American region.

scientific article published on 31 May 2017

Frequency of germline DNA genetic findings in an unselected prospective cohort of triple-negative breast cancer patients participating in a platinum-based neoadjuvant chemotherapy trial.

scientific article

Goserelin for ovarian protection during breast-cancer adjuvant chemotherapy.

scientific article published on March 2015

High-dose cytarabine plus high-dose methotrexate versus high-dose methotrexate alone in patients with primary CNS lymphoma: a randomised phase 2 trial.

scientific article published on 18 September 2009

Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Is Associated with Indigenous American Ancestry in Latin American Women

scientific article published on 03 April 2020

Ifosfamide plus Cisplatin as Primary Chemotherapy of Advanced Ovarian Cancer

scientific article published on 01 November 1997

Implication of miRNA in the diagnosis and treatment of breast cancer.

scientific article published on August 2011

In silico evaluation of DNA Damage Inducible Transcript 4 gene (DDIT4) as prognostic biomarker in several malignancies.

scientific article published on 8 May 2017

Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer

scientific article published on 28 September 2009

Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial

scientific article

Lapatinib-Related Rash and Breast Cancer Outcome in the ALTTO Phase III Randomized Trial

scientific article

Level of tumor-infiltrating lymphocytes and density of infiltrating immune cells in different malignancies

scientific article published on 17 October 2019

Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.

scientific article

Low-Dose Oral Cyclophosphamide and Methotrexate Maintenance for Hormone Receptor-Negative Early Breast Cancer: International Breast Cancer Study Group Trial 22-00.

scientific article

Maintenance of clinical efficacy after dose reduction of ixabepilone plus capecitabine in patients with anthracycline- and taxane-resistant metastatic breast cancer: a retrospective analysis of pooled data from 2 phase III randomized clinical trials

scientific article

Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets

scientific article published on 19 December 2013

Multicenter phase II study of plitidepsin in patients with relapsed/refractory non-Hodgkin's lymphoma.

scientific article

Mutation profiling identifies numerous rare drug targets and distinct mutation patterns in different clinical subtypes of breast cancers.

scientific article published on 27 April 2012

PIK3CA mutations in Peruvian patients with HER2-amplified and triple negative non-metastatic breast cancers.

scientific article published on 29 October 2014

PIK3CA-activating mutations and chemotherapy sensitivity in stage II-III breast cancer

scientific article published on 27 March 2008

Pazopanib: an antiangiogenic drug in perspective.

scientific article

Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer.

scientific article published on 8 August 2006

Phase I dose-escalation and pharmacokinetic study of ispinesib, a kinesin spindle protein inhibitor, administered on days 1 and 15 of a 28-day schedule in patients with no prior treatment for advanced breast cancer

scientific article published on 01 March 2012

Phase III, double-blind, randomized study comparing lapatinib plus paclitaxel with placebo plus paclitaxel as first-line treatment for metastatic breast cancer

scientific article published on 27 October 2008

Pixantrone dimaleate versus other chemotherapeutic agents as a single-agent salvage treatment in patients with relapsed or refractory aggressive non-Hodgkin lymphoma: a phase 3, multicentre, open-label, randomised trial

scientific article

Planning cancer control in Latin America and the Caribbean

scientific article

Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance

scientific article published on July 2012

Prognostic factors for patients with newly diagnosed brain metastasis from breast cancer

scientific article

Prolonged disease control in a patient with anthracycline- and taxane-resistant breast cancer.

scientific article published in November 2009

RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors

scientific article published on 29 October 2015

RNA Sequencing to Predict Response to Neoadjuvant Anti-HER2 Therapy: A Secondary Analysis of the NeoALTTO Randomized Clinical Trial.

scientific article published on 29 September 2016

Randomized trial of lapatinib versus placebo added to paclitaxel in the treatment of human epidermal growth factor receptor 2-overexpressing metastatic breast cancer.

scientific article published on 18 March 2013

Relationship between tumor-associated immune infiltrate and p16 staining over clinicopathological features in acral lentiginous melanoma

scientific article published on 16 February 2019

Repeated observation of immune gene sets enrichment in women with non-small cell lung cancer.

scientific article published on 06 March 2016

Role of undifferentiation markers and androgen receptor expression in triple-negative breast cancer

scientific article published on 22 July 2019

Selecting postoperative adjuvant systemic therapy for early stage breast cancer: A critical assessment of commercially available gene expression assays

scientific article

Targeted therapies: Combined lapatinib and paclitaxel in HER2-positive breast cancer.

scientific article published in June 2009

The impact of telemedicine on cancer care: real-world experience from a Peruvian institute during the COVID-19 pandemic

scientific article published in 2022

The modified International Prognostic Index can predict the outcome of localized primary intestinal lymphoma of both extranodal marginal zone B-cell and diffuse large B-cell histologies

scientific article published on 01 July 2002

The phosphatidyl inositol 3-kinase/AKT signaling pathway in breast cancer

scientific article published on December 2010

Topoisomerase II-α as a predictive factor of response to therapy with anthracyclines in locally advanced breast cancer.

scientific article published on 12 August 2010

Treatment of advanced hormone-sensitive breast cancer in postmenopausal women with exemestane alone or in combination with celecoxib

scientific article published in March 2008

Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence.

scientific article published on April 2016

Tumor infiltrating lymphocytes in triple negative breast cancer receiving neoadjuvant chemotherapy

scientific article published on October 2016

[Neoadjuvant chemotherapy in the treatment of locally advanced breast cancer].

scientific article published in March 2013

Paulina is supported by:

About Paulina

Help