Search filters

List of works by Lesa L. Aylward

"Intrinsic" elimination rate and dietary intake estimates for selected indicator PCBs: toxicokinetic modeling using serial sampling data in US subjects, 2005-2010.

scientific article

2,4-D exposure and risk assessment: comparison of external dose and biomonitoring based approaches

scientific article published on 24 September 2012

A margin-of-exposure approach to assessment of noncancer risks of dioxins based on human exposure and response data

scientific article

A mechanism-based cancer risk assessment for 1,4-dichlorobenzene

scientific article published on 4 July 2007

A pilot study of oral bioavailability of dioxins and furans from contaminated soils: Impact of differential hepatic enzyme activity and species differences

scientific article published on 22 October 2007

Advancing exposure characterization for chemical evaluation and risk assessment.

scientific article published in February 2010

Age as a determinant of phosphate flame retardant exposure of the Australian population and identification of novel urinary PFR metabolites

scientific article published on 29 September 2014

Age-related trends in urinary excretion of bisphenol A in Australian children and adults: evidence from a pooled sample study using samples of convenience.

scientific article published in January 2013

Age-specific reference ranges for polychlorinated biphenyls (PCB) based on the NHANES 2001-2002 survey.

scientific article

Application of human biomonitoring (HBM) of chemical exposure in the characterisation of health risks under REACH

scientific article published on 15 December 2011

Application of pharmacokinetic modelling for 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure assessment

scientific article

Assessment of margin of exposure based on biomarkers in blood: an exploratory analysis

scientific article

Background concentrations of dioxins, furans, and PCBs in Sprague-Dawley rats and juvenile swine

scientific article published on 01 June 2004

Biomonitoring Equivalents (BE) dossier for 2,4-dichlorophenoxyacetic acid (2,4-D) (CAS No. 94-75-7).

scientific article published on 22 May 2008

Biomonitoring Equivalents (BE) dossier for acrylamide (AA) (CAS No. 79-06-1).

scientific article

Biomonitoring Equivalents (BE) dossier for cadmium (Cd) (CAS No. 7440-43-9)

scientific article published on 22 May 2008

Biomonitoring Equivalents (BE) dossier for toluene (CAS No. 108-88-3).

scientific article published on 22 May 2008

Biomonitoring Equivalents (BE) dossier for trihalomethanes

scientific article

Biomonitoring Equivalents for benzene.

scientific article published on 09 December 2011

Biomonitoring Equivalents for interpretation of silver biomonitoring data in a risk assessment context.

scientific article

Biomonitoring Equivalents for interpretation of urinary fluoride

scientific article published on 08 April 2015

Biomonitoring Equivalents for molybdenum.

scientific article

Biomonitoring Equivalents for selenium

scientific article published on 25 July 2014

Biomonitoring data for 2,4-dichlorophenoxyacetic acid in the United States and Canada: interpretation in a public health risk assessment context using Biomonitoring Equivalents

scientific article

Biomonitoring equivalents for 2,2',4,4',5-pentabromodiphenylether (PBDE-99)

scientific article published on 03 April 2011

Biomonitoring equivalents for DDT/DDE.

scientific article published on 3 April 2011

Biomonitoring equivalents for deltamethrin

scientific article published on 3 April 2011

Biomonitoring equivalents for di-isononyl phthalate (DINP)

scientific article published on 03 April 2011

Biomonitoring equivalents for hexachlorobenzene.

scientific article published on 12 June 2010

Biomonitoring equivalents for inorganic arsenic.

scientific article published on 12 June 2010

Biomonitoring-based risk assessment for hexabromocyclododecane (HBCD).

scientific article published on 25 March 2011

California biomonitoring data: Comparison to NHANES and interpretation in a risk assessment context

scientific article

Chemical-specific screening criteria for interpretation of biomonitoring data for volatile organic compounds (VOCs)--application of steady-state PBPK model solutions

scientific article

Cohort study of workers at a New Zealand agrochemical plant to assess the effect of dioxin exposure on mortality

article

Comment on "Chronic disease and early exposure to air-borne mixtures. 2. Exposure assessment"

scientific article published on 01 March 2008

Concentration-dependent TCDD elimination kinetics in humans: toxicokinetic modeling for moderately to highly exposed adults from Seveso, Italy, and Vienna, Austria, and impact on dose estimates for the NIOSH cohort

scientific article published in January 2005

Consideration of dosimetry in evaluation of ToxCast™ data.

scientific article

Derivation of Biomonitoring Equivalents for cyfluthrin

scientific article published on 12 September 2009

Derivation of Biomonitoring Equivalents for di(2-ethylhexyl)phthalate (CAS No. 117-81-7).

scientific article published on 12 September 2009

Derivation of Biomonitoring Equivalents for di-n-butyl phthalate (DBP), benzylbutyl phthalate (BzBP), and diethyl phthalate (DEP).

scientific article published on 12 September 2009

Derivation of biomonitoring equivalent (BE) values for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds: a screening tool for interpretation of biomonitoring data in a risk assessment context

scientific article

Development of screening tools for the interpretation of chemical biomonitoring data

scientific article

Dioxin risks in perspective: past, present, and future.

scientific article

Does dioxin exert toxic effects in humans at or near current background body levels?: An evidence-based conclusion.

scientific article published in February 2006

Elevated levels of PFOS and PFHxS in firefighters exposed to aqueous film forming foam (AFFF).

scientific article published on 22 May 2015

Elimination rates of dioxin congeners in former chlorophenol workers from Midland, Michigan

scientific article published on 11 October 2012

Estimates of cancer potency of 2,3,4,7,8-pentachlorodibenzofuran using both nonlinear and linear approaches.

scientific article published on 22 August 2008

Estimates of cancer potency of 2,3,7,8-tetrachlorodibenzo(p)dioxin using linear and nonlinear dose-response modeling and toxicokinetics

scientific article published on 23 September 2009

Evaluation of NHANES biomonitoring data for volatile organic chemicals in blood: application of chemical-specific screening criteria

scientific article

Evaluation of biomonitoring data from the CDC National Exposure Report in a risk assessment context: perspectives across chemicals

scientific article

Evaluation of urinary speciated arsenic in NHANES: issues in interpretation in the context of potential inorganic arsenic exposure

scientific article published on 25 February 2014

Hepatic P450 enzyme activity, tissue morphology and histology of mink (Mustela vison) exposed to polychlorinated dibenzofurans

scientific article published on 21 May 2009

Hexavalent chromium reduction kinetics in rodent stomach contents

scientific article published on 08 June 2012

Human biomonitoring as a pragmatic tool to support health risk management of chemicals--examples under the EU REACH programme

scientific article published on 07 October 2010

Human biomonitoring assessment values: approaches and data requirements.

scientific article

Human response to dioxin: aryl hydrocarbon receptor (AhR) molecular structure, function, and dose-response data for enzyme induction indicate an impaired human AhR.

scientific article

Inter- and intra-individual variation in urinary biomarker concentrations over a 6-day sampling period. Part 1: metals

scientific article published on 13 August 2014

Inter- and intra-individual variation in urinary biomarker concentrations over a 6-day sampling period. Part 2: personal care product ingredients

scientific article published on 20 June 2014

Interpreting biomonitoring data for 2,4-dichlorophenoxyacetic acid: Update to Biomonitoring Equivalents and population biomonitoring data

scientific article

Interpreting estrogen screening assays in the context of potency and human exposure relative to natural exposures to phytoestrogens

scientific article published on 3 January 2014

Interpreting human biomonitoring data in a public health risk context using Biomonitoring Equivalents

scientific article published on December 20, 2011

Interpreting variability in population biomonitoring data: Role of elimination kinetics

scientific article published on May 16, 2012

Introduction to the Biomonitoring Equivalents Pilot Project: development of guidelines for the derivation and communication of Biomonitoring Equivalents

scientific article published on 06 March 2008

Is age an independent risk factor for chemically induced acute myelogenous leukemia in children?

scientific article published on September 2007

Issues in risk assessment for developmental effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds

scientific article

Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study.

scientific article

Monthly variation in faeces:blood concentration ratio of persistent organic pollutants over the first year of life: a case study of one infant.

scientific article published on 23 February 2016

Mortality in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin at a trichlorophenol plant in New Zealand

scientific article published in September 2009

Mortality rates among workers exposed to dioxins in the manufacture of pentachlorophenol

scientific article published in October 2009

Mortality risk among workers with exposure to dioxins.

scientific article

Nondestructive scat sampling in assessment of mink (Mustela vison) exposed to polychlorinated dibenzofurans (PCDFs).

scientific article published on 29 January 2008

Perfluorinated alkyl acids in the serum and follicular fluid of UK women with and without polycystic ovarian syndrome undergoing fertility treatment and associations with hormonal and metabolic parameters

scientific article published on 20 July 2018

Persistent organic pollutants in infants and toddlers: Relationship between concentrations in matched plasma and faecal samples

scientific article

Persistent organic pollutants in matched breast milk and infant faeces samples.

scientific article published in January 2015

Perspective on serum dioxin levels in the United States: an evaluation of the NHANES data

scientific article

Physiologically based pharmacokinetic model for humans orally exposed to chromium.

scientific article published on 17 April 2013

Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium.

scientific article published on 6 September 2012

Pooled biological specimens for human biomonitoring of environmental chemicals: opportunities and limitations

scientific article

Population variation in biomonitoring data for persistent organic pollutants (POPs): an examination of multiple population-based datasets for application to Australian pooled biomonitoring data

scientific article

Public health interpretation of trihalomethane blood levels in the United States: NHANES 1999-2004.

scientific article published on 24 June 2009

Rapid communication: partitioning of persistent lipophilic compounds, including dioxins, between human milk lipid and blood lipid: an initial assessment

scientific article

Relationships of chemical concentrations in maternal and cord blood: a review of available data.

scientific article

Relative cancer potencies of selected dioxin-like compounds on a body-burden basis: comparison to current toxic equivalency factors (TEFs)

scientific article published on 01 May 2006

Screening of population level biomonitoring data from the Canadian Health Measures Survey in a risk-based context

scientific article

Screening-level Biomonitoring Equivalents for tiered interpretation of urinary 3-phenoxybenzoic acid (3-PBA) in a risk assessment context

scientific article published on 4 November 2017

Short term variability in urinary bisphenol A in Australian children

article

Sources of variability in biomarker concentrations

scientific article published on January 2014

TCDD exposure estimation for workers at a New Zealand 2,4,5-T manufacturing facility based on serum sampling data

scientific article

TCDD exposure-response analysis and risk assessment

scientific article published on 01 August 2006

Temporal trends in human TCDD body burden: decreases over three decades and implications for exposure levels

scientific article published in September 2002

Temporal trends in serum polybrominated diphenyl ether concentrations in the Australian population, 2002-2013

article

The relative susceptibility of animals and humans to the carcinogenic hazard posed by exposure to 2,3,7,8-TCDD: an analysis using standard and internal measures of dose

scientific article published on 01 March 1997

Tissue distribution of dioxin-like compounds: potential impacts on systemic relative potency estimates

scientific article published on 13 May 2013

Toxicokinetics of 2,3,7,8-TCDF and 2,3,4,7,8-PeCDF in mink (Mustela vison) at ecologically relevant exposures

scientific article published on 19 June 2008

Urinary DEHP metabolites and fasting time in NHANES.

scientific article published on 17 August 2011

Urinary excretion and daily intake rates of diethyl phthalate in the general Canadian population

scientific article published on 15 September 2014

Using Biomonitoring Equivalents to interpret human biomonitoring data in a public health risk context

scientific article

Variation in urinary flow rates according to demographic characteristics and body mass index in NHANES: potential confounding of associations between health outcomes and urinary biomarker concentrations

scientific article

Variation in urinary spot sample, 24 h samples, and longer-term average urinary concentrations of short-lived environmental chemicals: implications for exposure assessment and reverse dosimetry

scientific article