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List of works by Alessandra Bragonzi

A new Chinese hamster ovary cell line expressing alpha2,6-sialyltransferase used as universal host for the production of human-like sialylated recombinant glycoproteins.

scientific article

Activation of Human Toll-like Receptor 4 (TLR4)·Myeloid Differentiation Factor 2 (MD-2) by Hypoacylated Lipopolysaccharide from a Clinical Isolate of Burkholderia cenocepacia

scientific article

Adaptation of Pseudomonas aeruginosa in Cystic Fibrosis airways influences virulence of Staphylococcus aureus in vitro and murine models of co-infection

scientific article

Aerosolized bovine lactoferrin reduces neutrophils and pro-inflammatory cytokines in mouse models of Pseudomonas aeruginosa lung infections.

scientific article published on 8 July 2016

Affecting Pseudomonas aeruginosa phenotypic plasticity by quorum sensing dysregulation hampers pathogenicity in murine chronic lung infection

scientific article

Airway epithelial cell-pathogen interactions

scientific article published in August 2004

Analysis of Pseudomonas aeruginosa cell envelope proteome by capture of surface-exposed proteins on activated magnetic nanoparticles.

scientific article

Anti-inflammatory action of lipid nanocarrier-delivered myriocin: therapeutic potential in cystic fibrosis.

scientific article

Antibiotic pressure compensates the biological cost associated with Pseudomonas aeruginosa hypermutable phenotypes in vitro and in a murine model of chronic airways infection

scientific article published on 01 February 2012

Assessing Pseudomonas aeruginosa virulence and the host response using murine models of acute and chronic lung infection

scientific article published in January 2014

BIIL 284 reduces neutrophil numbers but increases P. aeruginosa bacteremia and inflammation in mouse lungs

scientific article

Biochemical characterization of bona fide polycystin-1 in vitro and in vivo

scientific article published on 01 December 2001

Biological cost of hypermutation in Pseudomonas aeruginosa strains from patients with cystic fibrosis

scientific article published on 01 May 2007

Burkholderia cenocepacia strains isolated from cystic fibrosis patients are apparently more invasive and more virulent than rhizosphere strains

scientific article

Collaborative Cross Mice Yield Genetic Modifiers for Pseudomonas aeruginosa Infection in Human Lung Disease

scientific article published on 03 March 2020

Comparative genomics and biological characterization of sequential Pseudomonas aeruginosa isolates from persistent airways infection.

scientific article published on 29 December 2015

Complete Genome Sequence of Persistent Cystic Fibrosis Isolate Pseudomonas aeruginosa Strain RP73.

scientific article published in August 2013

Correction: The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa

scholarly article by Federica Moalli et al published 6 June 2011 in Journal of Immunology

Corrigendum to “Oxidative stress and antioxidant therapy in cystic fibrosis” [Biochim. Biophys. Acta 1822 (2012) 690–713]

scholarly article by Francesco Galli et al published December 2014 in BBA: Molecular Basis of Disease

Dampening Host Sensing and Avoiding Recognition in Pseudomonas aeruginosa Pneumonia.

scientific article published on 14 July 2011

Dissection of Host Susceptibility to Bacterial Infections and Its Toxins

scientific article

Efficacy of the Novel Antibiotic POL7001 in Preclinical Models of Pseudomonas aeruginosa Pneumonia.

scientific article

Expression of recombinant human granulocyte colony-stimulating factor in CHO dhfr- cells: new insights into the in vitro amplification expression system

scientific article

Extended Staphylococcus aureus persistence in cystic fibrosis is associated with bacterial adaptation

scientific article published on 8 October 2013

Factors contributing to epidemic MRSA clones replacement in a hospital setting.

scientific article

Fighting Back: Peptidomimetics as a New Weapon in the Battle Against Antibiotic Resistance

scientific article published on 01 March 2010

Genotypic and phenotypic relatedness of Pseudomonas aeruginosa isolates among the major cystic fibrosis patient cohort in Italy

scientific article

Host genetic background influences the response to the opportunistic Pseudomonas aeruginosa infection altering cell-mediated immunity and bacterial replication

scientific article

Host genetic diversity influences the severity of Pseudomonas aeruginosa pneumonia in the Collaborative Cross mice

scientific article published on 28 August 2015

Host-pathogen interplay in the respiratory environment of cystic fibrosis

scientific article published on 19 March 2015

IL-17A impairs host tolerance during airway chronic infection by Pseudomonas aeruginosa

scientific article

Impact of chronic pulmonary infection with Pseudomonas aeruginosa on transfection mediated by viral and nonviral vectors

scientific article published in March 2010

In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa

scientific article published on December 2015

Inactivation of thyA in Staphylococcus aureus attenuates virulence and has a strong impact on metabolism and virulence gene expression.

scientific article

Integrated whole-genome screening for Pseudomonas aeruginosa virulence genes using multiple disease models reveals that pathogenicity is host specific.

scientific article published on 3 April 2015

Lentiviral Vector Gene Therapy Protects XCGD Mice From Acute Staphylococcus aureus Pneumonia and Inflammatory Response.

scientific article published on 26 July 2016

Long term chronic Pseudomonas aeruginosa airway infection in mice

scientific article published on 17 March 2014

Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice

scientific article

Modelling co-infection of the cystic fibrosis lung by Pseudomonas aeruginosa and Burkholderia cenocepacia reveals influences on biofilm formation and host response

scientific article

Murine models of acute and chronic lung infection with cystic fibrosis pathogens.

scientific article published on 14 October 2010

Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model.

scientific article

Persistent cystic fibrosis isolate Pseudomonas aeruginosa strain RP73 exhibits an under-acylated LPS structure responsible of its low inflammatory activity.

scientific article

Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis

scientific article published on 06 May 2020

Positive signature-tagged mutagenesis in Pseudomonas aeruginosa: tracking patho-adaptive mutations promoting airways chronic infection

scientific article

Pseudomonas aeruginosa exploits lipid A and muropeptides modification as a strategy to lower innate immunity during cystic fibrosis lung infection

scientific article

Pseudomonas aeruginosa infection destroys the barrier function of lung epithelium and enhances polyplex-mediated transfection

scientific article published in July 2007

Pseudomonas aeruginosa reduces the expression of CFTR via post-translational modification of NHERF1.

scientific article published on 5 March 2014

Pseudomonas aeruginosaMicroevolution during Cystic Fibrosis Lung Infection Establishes Clones with Adapted Virulence

scientific article published on 07 May 2009

Repurposing the antimycotic drug flucytosine for suppression of Pseudomonas aeruginosa pathogenicity

scientific article

Response of CFTR-deficient mice to long-term chronic Pseudomonas aeruginosa infection and PTX3 therapy

scientific article

Role of Biophysical Parameters on ex Vivo and in Vivo Gene Transfer to the Airway Epithelium by Polyethylenimine/Albumin Complexes

article

Role of Iron Uptake Systems in Pseudomonas aeruginosa Virulence and Airway Infection

scientific article

Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection

scientific article published on 24 October 2011

Sequence diversity of the mucABD locus in Pseudomonas aeruginosa isolates from patients with cystic fibrosis

scientific article published on 01 November 2006

The IL-17A/IL-17RA axis in pulmonary defence and immunopathology

scientific article

The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa

scientific article published on 25 March 2011

The host genetic background defines diverse immune-reactivity and susceptibility to chronic Pseudomonas aeruginosa respiratory infection

scientific article published on 16 November 2016

The shedding-derived soluble receptor for advanced glycation endproducts sustains inflammation during acute Pseudomonas aeruginosa lung infection

scientific article published on 29 November 2016

The staphylococcal respiratory response regulator SrrAB induces ica gene transcription and polysaccharide intercellular adhesin expression, protecting Staphylococcus aureus from neutrophil killing under anaerobic growth conditions

article

Thymidine-Dependent Staphylococcus aureus Small-Colony Variants Are Induced by Trimethoprim-Sulfamethoxazole (SXT) and Have Increased Fitness during SXT Challenge

scientific article

Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections.

scientific article published on 17 February 2016

Upregulation of TMEM16A Protein in Bronchial Epithelial Cells by Bacterial Pyocyanin

scientific article published on 29 June 2015

Virulence of Burkholderia cepacia complex strains in gp91phox-/- mice.

scientific article