List of works - Peter I Mackenzie

A novel function for UDP glycosyltransferase 8: galactosidation of bile acids.

scientific article published on 17 December 2014

A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide

scientific article published on 13 July 2010

Activation of the pro-migratory bone morphogenetic protein receptor 1B gene in human MDA-MB-468 triple-negative breast cancer cells that over-express CYP2J2.

scientific article published on 05 October 2016

Advances in drug metabolism and pharmacogenetics research in Australia

scientific article published on 9 December 2016

Alteration of the function of the UDP-glucuronosyltransferase 1A subfamily by cytochrome P450 3A4: different susceptibility for UGT isoforms and UGT1A1/7 variants.

scientific article published on 19 November 2013

Amino terminal domains of human UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 associated with substrate selectivity and autoactivation.

scientific article published on 22 December 2006

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

scientific article published on 5 August 2016

Binding of inhibitory fatty acids is responsible for the enhancement of UDP-glucuronosyltransferase 2B7 activity by albumin: implications for in vitro-in vivo extrapolation

scientific article published on 19 January 2007

Carboxylic acid drug-induced DNA nicking in HEK293 cells expressing human UDP-glucuronosyltransferases: role of acyl glucuronide metabolites and glycation pathways.

scientific article

Characterization of the binding of drugs to human intestinal fatty acid binding protein (IFABP): potential role of IFABP as an alternative to albumin for in vitro-in vivo extrapolation of drug kinetic parameters.

scientific article

Characterization of the comparative drug binding to intra- (liver fatty acid binding protein) and extra- (human serum albumin) cellular proteins.

scientific article published on 24 March 2015

Comparative homology modeling of human cytochrome P4501A1 (CYP1A1) and confirmation of residues involved in 7-ethoxyresorufin O-deethylation by site-directed mutagenesis and enzyme kinetic analysis

scientific article published on 26 September 2007

Cooperative regulation of intestinal UDP-glucuronosyltransferases by CDX2 and HNF4α is mediated by a novel composite regulatory element

scientific article published on 8 March 2018

Coordinate regulation of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 genes by hepatocyte nuclear factor 1alpha and the caudal-related homeodomain protein 2.

scientific article published on April 2004

Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4

scientific article published on 17 July 2007

Differential induction of UDP glucuronosyltransferase activities towards various substrates after polycyclic aromatic hydrocarbon administration to rats ⬇️

scientific article published on 01 August 1982

Effects of Andrographis paniculata and Orthosiphon stamineus extracts on the glucuronidation of 4-methylumbelliferone in human UGT isoforms

scientific article published on 14 May 2010

Effects of amino acid substitutions at positions 33 and 37 on UDP-glucuronosyltransferase 1A9 (UGT1A9) activity and substrate selectivity.

scientific article published on 5 September 2012

Epirubicin upregulates UDP glucuronosyltransferase 2B7 expression in liver cancer cells via the p53 pathway.

scientific article published on 28 March 2014

Exemestane and Its Active Metabolite 17-Hydroexemestane Induce UDP-Glucuronosyltransferase (UGT) 2B17 Expression in Breast Cancer Cells.

scientific article

Expression of androgen receptor splice variants in clinical breast cancers.

scientific article published on 7 November 2015

Fatty acyl-CoA as an endogenous activator of UDP-glucuronosyltransferases

scientific article published on 24 May 2006

Forkhead box protein A1 regulates UDP-glucuronosyltransferase 2B15 gene transcription in LNCaP prostate cancer cells.

scientific article published on 24 August 2010

Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance.

scientific article

Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk.

scientific article published on February 2016

Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7

scientific article (publication date: February 2003)

Glucuronidation and the UDP-glucuronosyltransferases in health and disease.

scientific article published on March 2004

Glucuronidation of 3-hydroxybenzo(a)pyrene in liver microsomes

scientific article published on October 1, 1979

Hepatocyte nuclear factor1 transcription factors are essential for the UDP-glucuronosyltransferase 1A9 promoter response to hepatocyte nuclear factor 4alpha

scientific article published on 01 January 2007

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT

scientific article published on 21 February 2020

Homodimerization of UDP-glucuronosyltransferase 2B7 (UGT2B7) and identification of a putative dimerization domain by protein homology modeling.

scientific article published on 14 September 2011

Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression.

scientific article published on March 2004

Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.

scientific article

Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity.

scientific article published on 24 August 2005

Human UDP-glucuronosyltransferase expression in insect cells: ratio of active to inactive recombinant proteins and the effects of a C-terminal his-tag on glucuronidation kinetics.

scientific article

Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid

scientific article published in April 2004

Identification and characterization of functional hepatocyte nuclear factor 1-binding sites in UDP-glucuronosyltransferase genes

scientific article published on 01 January 2005

Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase.

scientific article

Identification of androgen receptor splice variant transcripts in breast cancer cell lines and human tissues.

scientific article published on 26 February 2014

Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes

scientific article

Induction of UDP-glucuronosyltransferase 2B15 gene expression by the major active metabolites of tamoxifen, 4-hydroxytamoxifen and endoxifen, in breast cancer cells

scientific article published on 20 March 2015

Induction of human UDP-Glucuronosyltransferase 2B7 gene expression by cytotoxic anticancer drugs in liver cancer HepG2 cells.

scientific article

Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substrates.

scientific article published on December 2007

Inhibition of UDP-glucuronosyltransferase 2b7-catalyzed morphine glucuronidation by ketoconazole: dual mechanisms involving a novel noncompetitive mode

scientific article published on 05 May 2006

Inhibition of human UDP-glucuronosyltransferase enzymes by lapatinib, pazopanib, regorafenib and sorafenib: Implications for hyperbilirubinemia

scientific article published on 5 January 2017

Inhibition of morphine glucuronidation in the liver microsomes of rats and humans by monoterpenoid alcohols

scientific article published on 08 August 2012

Inhibitory effects of adenine nucleotides and related substances on UDP-glucuronosyltransferase: structure-effect relationships and evidence for an allosteric mechanism.

scientific article published on 8 August 2007

Insights into the UDP-sugar selectivities of human UDP-glycosyltransferases (UGT): a molecular modeling perspective

scientific article published on 5 August 2015

Interaction of cytochrome P450 3A4 and UDP-glucuronosyltransferase 2B7: evidence for protein-protein association and possible involvement of CYP3A4 J-helix in the interaction

scientific article published on 21 January 2009

Interactions of styrene and styrene oxide with partially purified cytochrome P-450 and P-448 from rat liver microsomes ⬇️

scientific article published on 01 October 1981

Interactions with other human UDP-glucuronosyltransferases attenuate the consequences of the Y485D mutation on the activity and substrate affinity of UGT1A6.

scientific article published in February 2007

Intergenic Splicing between Four AdjacentUGTGenes (2B15, 2B29P2, 2B17, 2B29P1) Gives Rise to Variant UGT Proteins That Inhibit Glucuronidation via Protein-Protein Interactions

scientific article published on 29 June 2018

Introduction of an N-Glycosylation Site into UDP-Glucuronosyltransferase 2B3 Alters Its Sensitivity to Cytochrome P450 3A1-Dependent Modulation

scientific article published on 14 November 2016

Isoform selectivity and kinetics of morphine 3- and 6-glucuronidation by human udp-glucuronosyltransferases: evidence for atypical glucuronidation kinetics by UGT2B7.

scientific article published in September 2003

Isolation of the UDP-glucuronosyltransferase 1A3 and 1A4 proximal promoters and characterization of their dependence on the transcription factor hepatocyte nuclear factor 1alpha.

scientific article published on 18 October 2006

Modulation of UDP-glucuronosyltransferase 2B7 function by cytochrome P450s in vitro: differential effects of CYP1A2, CYP2C9 and CYP3A4.

scientific article

Modulation of UDP-glucuronosyltransferase function by cytochrome P450: evidence for the alteration of UGT2B7-catalyzed glucuronidation of morphine by CYP3A4.

scientific article published on 20 December 2004

Morphine glucuronidation and glucosidation represent complementary metabolic pathways that are both catalyzed by UDP-glucuronosyltransferase 2B7: kinetic, inhibition, and molecular modeling studies

scientific article published on 23 January 2014

Novel Nine-Exon AR Transcripts (Exon 1/Exon 1b/Exons 2-8) in Normal and Cancerous Breast and Prostate Cells

scientific article published on 27 December 2016

Polymorphic variations in the expression of the chemical detoxifying UDP glucuronosyltransferases.

scientific article

Polymorphisms and haplotypes of the UDP-glucuronosyltransferase 2B7 gene promoter.

scientific article published on 21 February 2014

Predicting human drug glucuronidation parameters: application of in vitro and in silico modeling approaches.

scientific article published on January 2004

Pro-migratory actions of the prostacyclin receptor in human breast cancer cells that over-express cyclooxygenase-2.

scientific article published on 9 June 2015

Protein-protein interactions between rat hepatic cytochromes P450 (P450s) and UDP-glucuronosyltransferases (UGTs): evidence for the functionally active UGT in P450-UGT complex

scientific journal article

Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation

scientific article

Recent advances in the in silico modelling of UDP glucuronosyltransferase substrates.

scientific article

Regulation of UDP glucuronosyltransferase genes.

scientific article

Regulation of UDP glucuronosyltransferases in the gastrointestinal tract.

scientific article published in September 2004

Regulation of UDP-Glucuronosyltransferase 2B15 by miR-331-5p in prostate cancer cells involves canonical and non-canonical target sites

scientific article published on 24 January 2018

Regulation of UDP-Glucuronosyltransferases UGT2B4 and UGT2B7 by MicroRNAs in Liver Cancer Cells.

scientific article published on 7 April 2017

Relationship between hyperbilirubinaemia and UDP-glucuronosyltransferase 1A1 (UGT1A1) polymorphism in adult HIV-infected Thai patients treated with indinavir

scientific article published in May 2006

S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen.

scientific article published in October 2005

Studies on the origin and excretion of serum alpha-amylase in the mouse

scientific article published on January 1, 1976

Sulfinpyrazone C-glucuronidation is catalyzed selectively by human UDP-glucuronosyltransferase 1A9.

scientific article published on 19 September 2006

Suppression of Cytochrome P450 3A4 Function by UDP-Glucuronosyltransferase 2B7 through a Protein-Protein Interaction: Cooperative Roles of the Cytosolic Carboxyl-Terminal Domain and the Luminal Anchoring Region.

scientific article published on 4 August 2015

The "albumin effect" and drug glucuronidation: bovine serum albumin and fatty acid-free human serum albumin enhance the glucuronidation of UDP-glucuronosyltransferase (UGT) 1A9 substrates but not UGT1A1 and UGT1A6 activities.

scientific article

The "albumin effect" and in vitro-in vivo extrapolation: sequestration of long-chain unsaturated fatty acids enhances phenytoin hydroxylation by human liver microsomal and recombinant cytochrome P450 2C9.

scientific article published on 6 February 2008

The Nonspecific Binding of Tyrosine Kinase Inhibitors to Human Liver Microsomes

scientific article

The cDNA sequence and expression of a variant 17 beta-hydroxysteroid UDP-glucuronosyltransferase ⬇️

scientific article published on May 25, 1990

The caudal-related homeodomain protein Cdx2 and hepatocyte nuclear factor 1alpha cooperatively regulate the UDP-glucuronosyltransferase 2B7 gene promoter.

scientific article published on July 2006

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases

scientific article

The homeodomain Pbx2-Prep1 complex modulates hepatocyte nuclear factor 1alpha-mediated activation of the UDP-glucuronosyltransferase 2B17 gene

scientific article published on 01 July 2002

The novel UDP glycosyltransferase 3A2: cloning, catalytic properties, and tissue distribution.

scientific article published on 18 November 2010

The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping and in vitro-in vivo extrapolation of drug clearance and drug-drug interaction potentia

scientific article published in February 2010

The regulation of UDP-glucuronosyltransferase genes by tissue-specific and ligand-activated transcription factors

scientific article published in February 2010

Transcriptional regulation of human UDP-glucuronosyltransferase genes.

scientific article

Transporter-mediated uptake of UDP-glucuronic acid by human liver microsomes: assay conditions, kinetics, and inhibition

scientific article published on 07 November 2014

UDPglucosyltransferase and Its Kinetic Fluorimetric Assay ⬇️

scientific article published on January 17, 1983

UGT3A: novel UDP-glycosyltransferases of the UGT superfamily

scientific article published on February 2010

List of works by Peter I Mackenzie

A novel function for UDP glycosyltransferase 8: galactosidation of bile acids.

A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide

Activation of the pro-migratory bone morphogenetic protein receptor 1B gene in human MDA-MB-468 triple-negative breast cancer cells that over-express CYP2J2.

Advances in drug metabolism and pharmacogenetics research in Australia

Alteration of the function of the UDP-glucuronosyltransferase 1A subfamily by cytochrome P450 3A4: different susceptibility for UGT isoforms and UGT1A1/7 variants.

Amino terminal domains of human UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 associated with substrate selectivity and autoactivation.

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

Binding of inhibitory fatty acids is responsible for the enhancement of UDP-glucuronosyltransferase 2B7 activity by albumin: implications for in vitro-in vivo extrapolation

Carboxylic acid drug-induced DNA nicking in HEK293 cells expressing human UDP-glucuronosyltransferases: role of acyl glucuronide metabolites and glycation pathways.

Characterization of the binding of drugs to human intestinal fatty acid binding protein (IFABP): potential role of IFABP as an alternative to albumin for in vitro-in vivo extrapolation of drug kinetic parameters.

Characterization of the comparative drug binding to intra- (liver fatty acid binding protein) and extra- (human serum albumin) cellular proteins.

Comparative homology modeling of human cytochrome P4501A1 (CYP1A1) and confirmation of residues involved in 7-ethoxyresorufin O-deethylation by site-directed mutagenesis and enzyme kinetic analysis

Cooperative regulation of intestinal UDP-glucuronosyltransferases by CDX2 and HNF4α is mediated by a novel composite regulatory element

Coordinate regulation of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 genes by hepatocyte nuclear factor 1alpha and the caudal-related homeodomain protein 2.

Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4

Differential induction of UDP glucuronosyltransferase activities towards various substrates after polycyclic aromatic hydrocarbon administration to rats ⬇️

Effects of Andrographis paniculata and Orthosiphon stamineus extracts on the glucuronidation of 4-methylumbelliferone in human UGT isoforms

Effects of amino acid substitutions at positions 33 and 37 on UDP-glucuronosyltransferase 1A9 (UGT1A9) activity and substrate selectivity.

Epirubicin upregulates UDP glucuronosyltransferase 2B7 expression in liver cancer cells via the p53 pathway.

Exemestane and Its Active Metabolite 17-Hydroexemestane Induce UDP-Glucuronosyltransferase (UGT) 2B17 Expression in Breast Cancer Cells.

Expression of androgen receptor splice variants in clinical breast cancers.

Fatty acyl-CoA as an endogenous activator of UDP-glucuronosyltransferases

Forkhead box protein A1 regulates UDP-glucuronosyltransferase 2B15 gene transcription in LNCaP prostate cancer cells.

Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance.

Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk.

Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7

Glucuronidation and the UDP-glucuronosyltransferases in health and disease.

Glucuronidation of 3-hydroxybenzo(a)pyrene in liver microsomes

Hepatocyte nuclear factor1 transcription factors are essential for the UDP-glucuronosyltransferase 1A9 promoter response to hepatocyte nuclear factor 4alpha

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT

Homodimerization of UDP-glucuronosyltransferase 2B7 (UGT2B7) and identification of a putative dimerization domain by protein homology modeling.

Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression.

Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.

Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity.

Human UDP-glucuronosyltransferase expression in insect cells: ratio of active to inactive recombinant proteins and the effects of a C-terminal his-tag on glucuronidation kinetics.

Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid

Identification and characterization of functional hepatocyte nuclear factor 1-binding sites in UDP-glucuronosyltransferase genes

Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase.

Identification of androgen receptor splice variant transcripts in breast cancer cell lines and human tissues.

Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes

Induction of UDP-glucuronosyltransferase 2B15 gene expression by the major active metabolites of tamoxifen, 4-hydroxytamoxifen and endoxifen, in breast cancer cells

Induction of human UDP-Glucuronosyltransferase 2B7 gene expression by cytotoxic anticancer drugs in liver cancer HepG2 cells.

Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substrates.

Inhibition of UDP-glucuronosyltransferase 2b7-catalyzed morphine glucuronidation by ketoconazole: dual mechanisms involving a novel noncompetitive mode

Inhibition of human UDP-glucuronosyltransferase enzymes by lapatinib, pazopanib, regorafenib and sorafenib: Implications for hyperbilirubinemia

Inhibition of morphine glucuronidation in the liver microsomes of rats and humans by monoterpenoid alcohols

Inhibitory effects of adenine nucleotides and related substances on UDP-glucuronosyltransferase: structure-effect relationships and evidence for an allosteric mechanism.

Insights into the UDP-sugar selectivities of human UDP-glycosyltransferases (UGT): a molecular modeling perspective

Interaction of cytochrome P450 3A4 and UDP-glucuronosyltransferase 2B7: evidence for protein-protein association and possible involvement of CYP3A4 J-helix in the interaction

Interactions of styrene and styrene oxide with partially purified cytochrome P-450 and P-448 from rat liver microsomes ⬇️

Interactions with other human UDP-glucuronosyltransferases attenuate the consequences of the Y485D mutation on the activity and substrate affinity of UGT1A6.

Intergenic Splicing between Four AdjacentUGTGenes (2B15, 2B29P2, 2B17, 2B29P1) Gives Rise to Variant UGT Proteins That Inhibit Glucuronidation via Protein-Protein Interactions

Introduction of an N-Glycosylation Site into UDP-Glucuronosyltransferase 2B3 Alters Its Sensitivity to Cytochrome P450 3A1-Dependent Modulation

Isoform selectivity and kinetics of morphine 3- and 6-glucuronidation by human udp-glucuronosyltransferases: evidence for atypical glucuronidation kinetics by UGT2B7.

Isolation of the UDP-glucuronosyltransferase 1A3 and 1A4 proximal promoters and characterization of their dependence on the transcription factor hepatocyte nuclear factor 1alpha.

Modulation of UDP-glucuronosyltransferase 2B7 function by cytochrome P450s in vitro: differential effects of CYP1A2, CYP2C9 and CYP3A4.

Modulation of UDP-glucuronosyltransferase function by cytochrome P450: evidence for the alteration of UGT2B7-catalyzed glucuronidation of morphine by CYP3A4.

Morphine glucuronidation and glucosidation represent complementary metabolic pathways that are both catalyzed by UDP-glucuronosyltransferase 2B7: kinetic, inhibition, and molecular modeling studies

Novel Nine-Exon AR Transcripts (Exon 1/Exon 1b/Exons 2-8) in Normal and Cancerous Breast and Prostate Cells

Polymorphic variations in the expression of the chemical detoxifying UDP glucuronosyltransferases.

Polymorphisms and haplotypes of the UDP-glucuronosyltransferase 2B7 gene promoter.

Predicting human drug glucuronidation parameters: application of in vitro and in silico modeling approaches.

Pro-migratory actions of the prostacyclin receptor in human breast cancer cells that over-express cyclooxygenase-2.

Protein-protein interactions between rat hepatic cytochromes P450 (P450s) and UDP-glucuronosyltransferases (UGTs): evidence for the functionally active UGT in P450-UGT complex

Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation

Recent advances in the in silico modelling of UDP glucuronosyltransferase substrates.

Regulation of UDP glucuronosyltransferase genes.

Regulation of UDP glucuronosyltransferases in the gastrointestinal tract.

Regulation of UDP-Glucuronosyltransferase 2B15 by miR-331-5p in prostate cancer cells involves canonical and non-canonical target sites

Regulation of UDP-Glucuronosyltransferases UGT2B4 and UGT2B7 by MicroRNAs in Liver Cancer Cells.

Relationship between hyperbilirubinaemia and UDP-glucuronosyltransferase 1A1 (UGT1A1) polymorphism in adult HIV-infected Thai patients treated with indinavir

S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen.

Studies on the origin and excretion of serum alpha-amylase in the mouse

Sulfinpyrazone C-glucuronidation is catalyzed selectively by human UDP-glucuronosyltransferase 1A9.

Suppression of Cytochrome P450 3A4 Function by UDP-Glucuronosyltransferase 2B7 through a Protein-Protein Interaction: Cooperative Roles of the Cytosolic Carboxyl-Terminal Domain and the Luminal Anchoring Region.

The "albumin effect" and drug glucuronidation: bovine serum albumin and fatty acid-free human serum albumin enhance the glucuronidation of UDP-glucuronosyltransferase (UGT) 1A9 substrates but not UGT1A1 and UGT1A6 activities.

The "albumin effect" and in vitro-in vivo extrapolation: sequestration of long-chain unsaturated fatty acids enhances phenytoin hydroxylation by human liver microsomal and recombinant cytochrome P450 2C9.

The Nonspecific Binding of Tyrosine Kinase Inhibitors to Human Liver Microsomes

The cDNA sequence and expression of a variant 17 beta-hydroxysteroid UDP-glucuronosyltransferase ⬇️