Search filters

List of works by A Richard Kitching

A new approach to idiopathic nephrotic syndrome

scientific article published on 01 October 2007

A pathogenetic role for mast cells in experimental crescentic glomerulonephritis

scientific article published on 30 November 2005

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

scientific article published on 29 July 2019

ANCA-Associated Vasculitis: Pathogenesis, Models, and Preclinical Testing.

scientific article published on September 2017

Activated Renal Dendritic Cells Cross Present Intrarenal Antigens After Ischemia-Reperfusion Injury.

scientific article

Advances in the pathogenesis of Goodpasture's disease: from epitopes to autoantibodies to effector T cells.

scientific article published on 27 May 2008

Amelioration of renal ischaemia-reperfusion injury by liposomal delivery of curcumin to renal tubular epithelial and antigen-presenting cells.

scientific article

Analysis of urinary macrophage migration inhibitory factor in systemic lupus erythematosus

scientific article published on 19 October 2018

Anti-neutrophil cytoplasmic antibodies and effector CD4+ cells play nonredundant roles in anti-myeloperoxidase crescentic glomerulonephritis

scientific article published on 12 June 2006

Antimyeloperoxidase antibodies rapidly induce alpha-4-integrin-dependent glomerular neutrophil adhesion.

scientific article published on 21 April 2009

Apoptotic Cell-Induced, Antigen-Specific Immunoregulation to Treat Experimental Antimyeloperoxidase GN

scientific article published on 23 July 2019

Atorvastatin enhances humoral immune responses but does not alter renal injury in experimental crescentic glomerulonephritis

scientific article published in October 2009

Biologics for the treatment of autoimmune renal diseases.

scientific article published on 7 March 2016

C5a receptor 1 promotes autoimmunity, neutrophil dysfunction and injury in experimental anti-myeloperoxidase glomerulonephritis

scientific article published on 11 December 2017

CD100 enhances dendritic cell and CD4+ cell activation leading to pathogenetic humoral responses and immune complex glomerulonephritis

scientific article published on 01 September 2006

CD4+ Th1 cells are effectors in lupus nephritis—but what are their targets?

scientific article published on 01 November 2012

CD8+ T Cells Effect Glomerular Injury in Experimental Anti-Myeloperoxidase GN.

scientific article published on 10 June 2016

CD8+ cells and glomerular crescent formation: outside-in as well as inside-out

scientific article published on 09 July 2018

CD80 and CD86 costimulatory molecules regulate crescentic glomerulonephritis by different mechanisms

scientific article published in August 2005

CX3CR1 reduces kidney fibrosis by inhibiting local proliferation of profibrotic macrophages

scientific article

Chemokines as therapeutic targets in renal disease.

scientific article

Chimeric antigen receptor T (CAR T) cells: another cancer therapy with potential applications in kidney disease and transplantation?

scientific article published on 01 July 2018

Chyluria: When is proteinuria 'not proteinuria'?

scientific article

Contributions of IL-1beta and IL-1alpha to crescentic glomerulonephritis in mice

scientific article published in April 2004

Corrigendum: Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus

scientific article published on 01 April 2016

Deficiency of annexin A1 in CD4+ T cells exacerbates T cell-dependent inflammation.

scientific article

Dendritic cells in progressive renal disease: some answers, many questions

scientific article published on 15 April 2014

Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells

scientific article published on 3 May 2017

Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes.

scientific article published on 21 February 2018

Effects of CTLA4-Fc on glomerular injury in humorally-mediated glomerulonephritis in BALB/c mice

scientific article published on 01 June 2002

Endogenous CD100 promotes glomerular injury and macrophage recruitment in experimental crescentic glomerulonephritis.

scientific article

Endogenous IL-13 limits humoral responses and injury in experimental glomerulonephritis but does not regulate Th1 cell-mediated crescentic glomerulonephritis

scientific article published on 01 September 2004

Endogenous Tim-1 (Kim-1) promotes T-cell responses and cell-mediated injury in experimental crescentic glomerulonephritis

scientific article published on 28 December 2011

Endogenous Tim-1 promotes severe systemic autoimmunity and renal disease MRL-Fas(lpr) mice

scientific article published on 12 March 2014

Endogenous Toll-Like Receptor 9 Regulates AKI by Promoting Regulatory T Cell Recruitment

scientific article published on 26 June 2015

Endogenous alpha2-antiplasmin does not enhance glomerular fibrin deposition or injury in glomerulonephritis

scientific article published in September 2003

Endogenous foxp3(+) T-regulatory cells suppress anti-glomerular basement membrane nephritis

scientific article published on 19 January 2011

Endogenous interleukin (IL)-17A promotes pristane-induced systemic autoimmunity and lupus nephritis induced by pristane

scientific article published on 01 June 2014

Endogenous interleukin-10 regulates Th1 responses that induce crescentic glomerulonephritis

scientific article published on 01 February 2000

Endogenous myeloperoxidase promotes neutrophil-mediated renal injury, but attenuates T cell immunity inducing crescentic glomerulonephritis

scientific article published on 31 January 2007

Endogenous regulatory T cells adhere in inflamed dermal vessels via ICAM-1: association with regulation of effector leukocyte adhesion

scientific article published on 25 January 2012

Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis

scientific article published on March 15, 2013

Epstein-Barr virus encephalitis in solid organ transplantation

scientific article

Experimental Antiglomerular Basement Membrane GN Induced by a Peptide from Actinomyces

scientific article published on 22 May 2020

Experimental autoimmune Goodpasture's disease: a pathogenetic role for both effector cells and antibody in injury

scientific article published on 01 February 2005

Experimental autoimmune anti-glomerular basement membrane glomerulonephritis: a protective role for IFN-gamma.

scientific article

FMS-like tyrosine kinase 3 ligand treatment does not ameliorate experimental rapidly progressive glomerulonephritis

scientific article

FcγRIIB regulates T-cell autoreactivity, ANCA production, and neutrophil activation to suppress anti-myeloperoxidase glomerulonephritis.

scientific article published on 28 May 2014

Fibrin independent proinflammatory effects of tissue factor in experimental crescentic glomerulonephritis

scientific article published in August 2004

Formyl peptide receptor activation inhibits the expansion of effector T cells and synovial fibroblasts and attenuates joint injury in models of rheumatoid arthritis

scientific article published on 04 June 2018

Four pediatric patients with autosomal recessive polycystic kidney disease developed new-onset diabetes after renal transplantation.

scientific article published on 13 August 2014

From bench to pet shop to bedside? The environment and immune function in mice

scientific article published on 28 September 2016

Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus

scientific article published on 17 May 2019

Glomerular expression of CD80 and CD86 is required for leukocyte accumulation and injury in crescentic glomerulonephritis

scientific article published on 08 June 2005

Glomerulonephritis Induced by Heterologous Anti-GBM Globulin as a Planted Foreign Antigen

scientific article published on August 2014

Goodpasture's autoimmune disease - A collagen IV disorder.

scientific article published on 12 May 2018

Granulocyte macrophage colony-stimulating factor expression by both renal parenchymal and immune cells mediates murine crescentic glomerulonephritis

scientific article published on 20 July 2005

HLA and kidney disease: from associations to mechanisms

scientific article published on 01 October 2018

HLA-DR15-specific inhibition attenuates autoreactivity to the Goodpasture antigen

scientific article published on 16 May 2019

Histopathologic and clinical predictors of kidney outcomes in ANCA-associated vasculitis

scientific article published on 30 October 2013

IL-12 directs severe renal injury, crescent formation and Th1 responses in murine glomerulonephritis

scientific article published on 01 January 1999

IL-12p40 and IL-18 in crescentic glomerulonephritis: IL-12p40 is the key Th1-defining cytokine chain, whereas IL-18 promotes local inflammation and leukocyte recruitment

scientific article published on 11 May 2005

IL-18 is redundant in T-cell responses and in joint inflammation in antigen-induced arthritis

scientific article published on 01 April 2006

IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis

scientific article published on 22 May 2009

Identifying Outcomes Important to Patients with Glomerular Disease and Their Caregivers

scientific article published on 30 April 2020

Imaging Leukocyte Responses in the Kidney.

scientific article published on 27 October 2016

Immune modulation with interleukin-4 and interleukin-10 prevents crescent formation and glomerular injury in experimental glomerulonephritis

scientific article published on 01 February 1997

Immune-mediated kidney disease in 2017: Progress in mechanisms and therapy for immunological kidney disease

scientific article published on 18 December 2017

Immunopathogenesis of crescentic glomerulonephritis.

scientific article

Induced regulatory T cells are phenotypically unstable and do not protect mice from rapidly progressive glomerulonephritis

scientific article published on 8 September 2016

Inducible co-stimulatory molecule ligand is protective during the induction and effector phases of crescentic glomerulonephritis

scientific article published on 15 March 2006

Inflammasomes in the Kidney

scientific article published on 01 January 2018

Innate IL-17A-producing leukocytes promote acute kidney injury via inflammasome and Toll-like receptor activation

scientific article published on 14 March 2014

Interleukin-10 inhibits experimental mesangial proliferative glomerulonephritis

scientific article

Interleukin-17A promotes early but attenuates established disease in crescentic glomerulonephritis in mice

scientific article

Interleukin-17RA Promotes Humoral Responses and Glomerular Injury in Experimental Rapidly Progressive Glomerulonephritis

scientific article published on 10 December 2016

Interleukin-4 deficiency enhances Th1 responses and crescentic glomerulonephritis in mice

scientific article published on 01 January 1998

Intrarenal Toll-like receptor 4 and Toll-like receptor 2 expression correlates with injury in antineutrophil cytoplasmic antibody-associated vasculitis

scientific article published on 20 June 2018

Intrarenal antigens activate CD4+ cells via co-stimulatory signals from dendritic cells

scientific article published on 9 January 2008

Intrinsic renal cell and leukocyte-derived TLR4 aggravate experimental anti-MPO glomerulonephritis.

scientific article published on 15 September 2010

Intrinsic renal cell expression of CD40 directs Th1 effectors inducing experimental crescentic glomerulonephritis

scientific article published on 01 November 2003

In Vivo Imaging of Inflamed Glomeruli Reveals Dynamics of Neutrophil Extracellular Trap Formation in Glomerular Capillaries.

scientific article published on 17 December 2016

Lymphocytes promote albuminuria, but not renal dysfunction or histological damage in a mouse model of diabetic renal injury.

scientific article published on 27 April 2010

Mast Cell Stabilization Ameliorates Autoimmune Anti-Myeloperoxidase Glomerulonephritis

scientific article published on 15 September 2015

Mast Cells Mediate Acute Kidney Injury through the Production of TNF

scientific article published on October 21, 2011

Mast cell activation and degranulation promotes renal fibrosis in experimental unilateral ureteric obstruction.

scientific article

Mast cells contribute to peripheral tolerance and attenuate autoimmune vasculitis.

scientific article

More targeted treatments for lupus nephritis: is the future (nearly) here?

scientific article published on 05 October 2005

Mouse models of anti-neutrophil cytoplasmic antibody-associated vasculitis

scientific article published on January 2015

Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus

scientific article published on 16 December 2012

Myeloperoxidase (MPO)-specific CD4+ T cells contribute to MPO-anti-neutrophil cytoplasmic antibody (ANCA) associated glomerulonephritis.

scientific article published in March 2013

Myeloperoxidase Peptide-Based Nasal Tolerance in Experimental ANCA-Associated GN.

scientific article published on 5 June 2015

Neutrophil myeloperoxidase regulates T-cell-driven tissue inflammation in mice by inhibiting dendritic cell function.

scientific article published on 18 March 2013

Neutrophil-Mediated Regulation of Innate and Adaptive Immunity: The Role of Myeloperoxidase

scientific article

OX40 ligand is inhibitory during the effector phase of crescentic glomerulonephritis

scientific article published on 01 March 2019

Omeprazole-induced acute interstitial nephritis: a possible Th1-Th17-mediated injury?

scientific article published on 01 June 2014

Pathogenic Role for γδ T Cells in Autoimmune Anti-Myeloperoxidase Glomerulonephritis.

scientific article published on 27 September 2017

Patrolling monocytes promote intravascular neutrophil activation and glomerular injury in the acutely inflamed glomerulus

scientific article published on 15 August 2016

Plasmin is not protective in experimental renal interstitial fibrosis

scientific article

Plasminogen activator inhibitor-1 production is pathogenetic in experimental murine diabetic renal disease

scientific article published on 06 April 2007

Plasminogen and plasminogen activators protect against renal injury in crescentic glomerulonephritis

scientific article

Platelet recruitment to the inflamed glomerulus occurs via an alphaIIbbeta3/GPVI-dependent pathway.

scientific article

Platelet retention in inflamed glomeruli occurs via selective prolongation of interactions with immune cells

scientific article published on 03 December 2018

Programmed death 1 and its ligands do not limit experimental foreign antigen-induced immune complex glomerulonephritis

scientific article published on 5 June 2015

Regulatory T cells dynamically regulate selectin ligand function during multiple challenge contact hypersensitivity.

scientific article published in October 2014

Regulatory T cells in immune-mediated renal disease.

scientific article published on 24 July 2015

Regulatory T cells in renal disease.

scientific article published on 30 January 2018

Renal dendritic cells adopt a pro-inflammatory phenotype in obstructive uropathy to activate T cells but do not directly contribute to fibrosis

scientific article published on 08 November 2011

Renal participation of myeloperoxidase in antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis

scientific article published on 15 July 2015

Signal transducer and activation of transcription 6 (STAT6) regulates T helper type 1 (Th1) and Th17 nephritogenic immunity in experimental crescentic glomerulonephritis

scientific article published in November 2011

Standardized Outcomes in Nephrology-Glomerular Disease (SONG-GD): establishing a core outcome set for trials in patients with glomerular disease

scientific article published on 01 June 2019

Suppression of Autoimmunity and Renal Disease in Pristane-Induced Lupus by Myeloperoxidase

scientific article published on 01 July 2015

T cell mediated autoimmune glomerular disease in mice

scientific article

T-bet deficiency attenuates renal injury in experimental crescentic glomerulonephritis.

scientific article published on 30 January 2008

TLR9 and TLR4 are required for the development of autoimmunity and lupus nephritis in pristane nephropathy

scientific article published on 01 December 2010

Targeting IL-17 and IL-23 in Immune Mediated Renal Disease

scientific article

Targeting renal macrophage accumulation via c-fms kinase reduces tubular apoptosis but fails to modify progressive fibrosis in the obstructed rat kidney.

scientific article

Th1 and Th2 T helper cell subsets affect patterns of injury and outcomes in glomerulonephritis

scientific article

Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis

scientific article

The C3aR promotes macrophage infiltration and regulates ANCA production but does not affect glomerular injury in experimental anti-myeloperoxidase glomerulonephritis.

scientific article published on 9 January 2018

The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN.

scientific article published on 14 February 2013

The IL-27 receptor has biphasic effects in crescentic glomerulonephritis mediated through Th1 responses.

scientific article

The NLRP3 inflammasome in kidney disease and autoimmunity.

scientific article published on 24 March 2016

The Players: Cells Involved in Glomerular Disease.

scientific article published on 12 April 2016

The Th17-defining transcription factor RORγt promotes glomerulonephritis

scientific article

The cytoplasmic domain of tissue factor in macrophages augments cutaneous delayed-type hypersensitivity

scientific article published on 07 January 2008

The emergence of TH17 cells as effectors of renal injury.

scientific article published on February 2011

The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis.

scientific article

The renal draining lymph nodes in acute inflammatory kidney disease

scientific article published on 01 February 2019

The role of flow cytometric ANCA detection in screening for acute pauci-immune crescentic glomerulonephritis

scientific article published on 01 February 2004

The tumour suppressor gene p53 modulates the severity of antigen-induced arthritis and the systemic immune response

scientific article

Thymic deletion and regulatory T cells prevent antimyeloperoxidase GN.

scientific article published on 7 February 2013

Tim-1 promotes cisplatin nephrotoxicity

scientific article published on 10 August 2011

Toll-like receptor 2 induces Th17 myeloperoxidase autoimmunity while Toll-like receptor 9 drives Th1 autoimmunity in murine vasculitis

scientific article published on 01 April 2011

Toll-like receptor 9 enhances nephritogenic immunity and glomerular leukocyte recruitment, exacerbating experimental crescentic glomerulonephritis.

scientific article

Urinary B-cell-activating factor of the tumour necrosis factor family (BAFF) in systemic lupus erythematosus

scientific article published on 09 October 2018