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List of works by Georges Lacaud

A developmentally regulated heparan sulfate epitope defines a subpopulation with increased blood potential during mesodermal differentiation

scientific article published on 11 September 2008

A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects.

scientific article

Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses.

scientific article

B cell receptor expression level determines the fate of developing B lymphocytes: receptor editing versus selection.

scientific article

Blood cell generation from the hemangioblast.

scientific article published on 25 October 2009

CUL2<sup>LRR1</sup> , TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle

scientific article published on 15 February 2021

Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification

scientific journal article

Development of the hematopoietic system in the mouse.

scientific article

Developmental-stage-dependent transcriptional response to leukaemic oncogene expression.

scientific article published on 28 May 2015

Direct reprogramming of murine fibroblasts to hematopoietic progenitor cells

scientific article published on 26 November 2014

ETV2 expression marks blood and endothelium precursors, including hemogenic endothelium, at the onset of blood development

scientific article published on 16 July 2012

Embryonic stem cell-derived hemangioblasts remain epigenetically plastic and require PRC1 to prevent neural gene expression.

scientific article published on 28 September 2010

Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code

scientific article published on 19 September 2008

Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

scientific article published on 02 December 2021

FOXF1 inhibits hematopoietic lineage commitment during early mesoderm specification

scientific article published on 20 August 2015

Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells

scientific article

GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1.

scientific article

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

scientific journal article

Haploinsufficiency of Runx1 results in the acceleration of mesodermal development and hemangioblast specification upon in vitro differentiation of ES cells

scientific article published on 2 October 2003

Identification and characterization of a novel transcriptional target of RUNX1/AML1 at the onset of hematopoietic development

scientific article published on 15 April 2011

Identification of a fetal hematopoietic precursor with B cell, T cell, and macrophage potential

scientific article published on 01 December 1998

Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets

scientific article published on 04 November 2019

In vitro differentiation of mouse embryonic stem cells as a model of early hematopoietic development.

scientific article

In vivo repopulating activity emerges at the onset of hematopoietic specification during embryonic stem cell differentiation.

scientific article published on 5 February 2015

Influencing hematopoietic differentiation of mouse embryonic stem cells using soluble heparin and heparan sulfate saccharides.

scientific article published on 10 December 2010

Integrated analyses of chromatin accessibility and gene expression data for elucidating the transcriptional regulatory mechanisms during early hematopoietic development in mouse.

scientific article published on 18 March 2013

Isolation of recombinant partial gag gene product p18 (HIV-1Bru) from Escherichia coli

scientific article published on 01 August 1989

Leptin stimulates fetal and adult erythroid and myeloid development

scientific journal article

MOZ-mediated repression of p16(INK) (4) (a) is critical for the self-renewal of neural and hematopoietic stem cells

scientific article published on June 2014

Mouse RUNX1C regulates premegakaryocytic/erythroid output and maintains survival of megakaryocyte progenitors

scientific article

Origin of blood cells and HSC production in the embryo.

scientific article published on 23 February 2012

Quantitative proteomics analysis demonstrates post-transcriptional regulation of embryonic stem cell differentiation to hematopoiesis

scientific article

RUNX transcription factors: orchestrators of development

scientific article published on 05 September 2019

RUNX1 marks a luminal castration resistant lineage established at the onset of prostate development

scientific article published on 07 October 2020

RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence.

scientific article

RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.

scientific article

Regulation of RUNX1 dosage is crucial for efficient blood formation from hemogenic endothelium.

scientific article published on 12 March 2018

Regulation of hemangioblast development.

scientific article

Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro

scientific article published in July 2002

SOX7 regulates the expression of VE-cadherin in the haemogenic endothelium at the onset of haematopoietic development

scientific article published in May 2012

Sequential development of hematopoietic and cardiac mesoderm during embryonic stem cell differentiation

scientific article

Smooth muscle cells largely develop independently of functional hemogenic endothelium.

scientific article published on 5 November 2013

Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification

scientific article published on 2 October 2009

System-wide studies of the transcriptional programming of chromatin during early hematopoietic development

scientific article published on 18 March 2013

The Flk1-Cre-mediated deletion of ETV2 defines its narrow temporal requirement during embryonic hematopoietic development

scientific article published in July 2012

The MYSTerious MOZ, a histone acetyltransferase with a key role in haematopoiesis ⬇️

scientific article published on June 1, 2013

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

scientific article

The hematopoietic master regulator RUNX1 reshapes the epigenetic landscape at the onset of hematopoiesis

The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors.

scientific article published on 05 March 2009

The paralogous hematopoietic regulators Lyl1 and Scl are coregulated by Ets and GATA factors, but Lyl1 cannot rescue the early Scl-/- phenotype.

scientific article published on 19 October 2006

The sequential expression of CD40 and Icam2 defines progressive steps in the formation of blood precursors from the mesoderm germ layer

scientific article published in June 2010

The stepwise specification of embryonic stem cells to hematopoietic fate is driven by sequential exposure to Bmp4, activin A, bFGF and VEGF.

scientific article

The transcription factor Mxd4 controls the proliferation of the first blood precursors at the onset of hematopoietic development in vitro

scientific article published on 23 July 2011

Tracking mesoderm formation and specification to the hemangioblast in vitro

scientific article

Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation

scientific article

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