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List of works by Iztok Grabnar

A nonlinear mixed effects modelling analysis of topiramate pharmacokinetics in patients with epilepsy

scientific article published on January 2010

A population pharmacokinetic evaluation of the influence of CYP2D6 genotype on risperidone metabolism in patients with acute episode of schizophrenia

scientific article published on 3 July 2010

A simple dried blood spot method for clinical pharmacological analyses of etoposide in cancer patients using liquid chromatography and fluorescence detection

scientific article published on 26 October 2015

Antioxidants as a preventive treatment for epileptic process: a review of the current status

scientific article published on December 2014

Application of Counter-propagation Artificial Neural Networks in Prediction of Topiramate Concentration in Patients with Epilepsy.

scientific article published on December 2015

Applying the methodology of Design of Experiments to stability studies: a Partial Least Squares approach for evaluation of drug stability.

scientific article published in December 2017

Association of SOD2, GPX1, CAT, and TNF genetic polymorphisms with oxidative stress, neurochemistry, psychopathology, and extrapyramidal symptoms in schizophrenia

scientific article

Association of dietary type with fecal microbiota in vegetarians and omnivores in Slovenia.

scientific article

Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma

scientific article

Bisoprolol pharmacokinetics and body composition in patients with chronic heart failure: a longitudinal study

scientific article published on 21 March 2016

Combined extracts of Echinacea angustifolia DC. and Zingiber officinale Roscoe in softgel capsules: Pharmacokinetics and immunomodulatory effects assessed by gene expression profiling

scientific article published on 16 September 2019

Comparative bioavailability of two oral formulations of clopidogrel: determination of clopidogrel and its carboxylic acid metabolite (SR26334) under fasting and fed conditions in healthy subjects

scientific article published in March 2014

Correlation of in vitro and in vivo paracetamol availability from layered excipient suppositories

scientific article published in November 1999

Current clinical evidence on topiramate pharmacokinetics

scientific article published in July 2009

Curriculum Mapping of the Master's Program in Pharmacy in Slovenia with the PHAR-QA Competency Framework

scientific article published on 2 May 2017

Decreased cortisol secretion by adrenal glands perfused with the P-glycoprotein inhibitor valspodar and mitotane or doxorubicin.

scientific article published in April 2000

Determination of warfarin enantiomers and hydroxylated metabolites in human blood plasma by liquid chromatography with achiral and chiral separation

scientific article published in April 2005

Development and pharmacokinetic evaluation of erythromycin lipidic formulations for oral administration in rainbow trout (Oncorhynchus mykiss)

scientific article published on 22 March 2011

Development and preclinical pharmacokinetics of a novel subcutaneous thermoresponsive system for prolonged delivery of heparin

scientific article published on 31 October 2015

Development and validation of a simple and sensitive size-exclusion chromatography method for quantitative determination of heparin in pharmaceuticals.

scientific article published in March 2015

Diagnostic and therapeutic value of naloxone after intoxication with tramadol in a young girl

scientific article published on 01 December 2009

Downregulation of ABCB1 gene in patients with total hip or knee arthroplasty influences pharmacokinetics of rivaroxaban: a population pharmacokinetic-pharmacodynamic study

scientific article published on 06 February 2019

Dried blood spots for monitoring and individualization of antiepileptic drug treatment.

scientific article published on 17 April 2015

Effect of Long-term Topiramate Therapy on Serum Bicarbonate and Potassium Levels in Adult Epileptic Patients

scientific article published on 08 May 2014

Fast and Simple LC-MS/MS Method for Rifampicin Quantification in Human Plasma

scientific article published on 03 February 2019

Febrile neutropenia in chemotherapy treated small-cell lung cancer patients

scientific article

Improving Biopharmaceutical Properties of Vinpocetine Through Cocrystallization.

scientific article

Influence of CYP2C9 polymorphisms, demographic factors and concomitant drug therapy on warfarin metabolism and maintenance dose

scientific article published in January 2005

Influence of P-glycoprotein inhibition on secretion of ivermectin and doramectin by milk in lactating sheep

scientific article published on 12 March 2011

Influence of cancer cachexia on drug liver metabolism and renal elimination in rats

scientific article

Influence of chitosan and polycarbophil on permeation of a model hydrophilic drug into the urinary bladder wall

scientific article published in April 2003

Interdependence of histamine and methylhistamine kinetics: modelling and simulation approach

scientific article published in November 1999

Investigation of the influence of CYP1A2 and CYP2C19 genetic polymorphism on 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide (A77 1726) pharmacokinetics in leflunomide-treated patients with rheumatoid arthritis.

scientific article

Ivermectin pharmacokinetics in lactating sheep

scientific article published in March 2002

Kinetics of abamectin disposition in blood plasma and milk of lactating dairy sheep and suckling lambs

scientific article published on 16 October 2007

Linearity of eprinomectin pharmacokinetics in lactating dairy sheep following pour-on administration: excretion in milk and exposure of suckling lambs

scientific article published on 04 March 2008

MDR1 gene polymorphisms and response to acute risperidone treatment

scientific article published on 11 January 2010

Maturation of midazolam clearance in critically ill children with severe bronchiolitis: A population pharmacokinetic analysis

scientific article published on 15 October 2019

Mechanochemically induced disordered structures of vincamine: The different mediation of two cross-linked polymers

scientific article published on 19 June 2012

Methylprednisolone, cortisol and the cell-mediated immune response in children after ventricular septal defect repair

scientific article published in January 2007

Microbes in Infant Gut Development: Placing Abundance Within Environmental, Clinical and Growth Parameters

scientific article published on 11 September 2017

Natural Deep Eutectic Solvents (NADES) as a Tool for Bioavailability Improvement: Pharmacokinetics of Rutin Dissolved in Proline/Glycine after Oral Administration in Rats: Possible Application in Nutraceuticals

scientific article published on 14 November 2016

Natural Deep Eutectic Solvents (NADES) to Enhance Berberine Absorption: An In Vivo Pharmacokinetic Study.

scientific article published on 8 November 2017

Oral bioavailability of silymarin phytocomplex formulated as self-emulsifying pellets

scientific article published on 26 November 2010

Oxidative stress in schizophrenia

scientific article

Oxidative stress in schizophrenia patients treated with long-acting haloperidol decanoate

scientific article published on 13 September 2013

Peak Concentrations of Ustekinumab After Intravenous Induction Therapy Identify Patients With Crohn's Disease Likely to Achieve Endoscopic and Biochemical Remission

scientific article published on 25 February 2020

Pharmacokinetics and immunomodulatory effect of lipophilic Echinacea extract formulated in softgel capsules

scientific article published on 8 October 2015

Pharmacokinetics and immunomodulatory effects of phytotherapeutic lozenges (bonbons) with Echinacea purpurea extract.

scientific article published on 25 June 2008

Pharmacokinetics of lamotrigine and its metabolite N-2-glucuronide: Influence of polymorphism of UDP-glucuronosyltransferases and drug transporters

scientific article published on 20 April 2016

Physicochemical and preclinical pharmacokinetic and toxicological evaluation of LK-423--a new phthalimido-desmuramyl-dipeptide derivative with immunomodulating activity.

scientific article published in November 2009

Plasma pharmacokinetics of abamectin in fallow deer (Cervus dama dama) following subcutaneous administration

scientific article published on 28 December 2010

Population Pharmacokinetic Approach of Immunosuppressive Therapy in Kidney Transplant Patients.

scientific article published on 21 December 2015

Population pharmacokinetic model of carbamazepine derived from routine therapeutic drug monitoring data

scientific article

Population pharmacokinetic modelling of tramadol using inverse Gaussian function for the assessment of drug absorption from prolonged and immediate release formulations

scientific article published on 8 July 2014

Population pharmacokinetics of rituximab in patients with diffuse large B-cell lymphoma and association with clinical outcome

scientific article

Population pharmacokinetics of topiramate in adult patients with epilepsy using nonlinear mixed effects modelling

scientific article published on 25 July 2013

Predicting the anti-hypertensive effect of nitrendipine from plasma concentration profiles using artificial neural networks

scientific article published in December 2005

Prediction of Saxagliptin Stability using a New Approach Based on Partial Least Squares and Design of Experiments

scientific article published on 03 September 2020

Preliminary toxicokinetic study of BPA in lactating dairy sheep after repeated dietary and subcutaneous administration

scientific article published on 16 April 2020

Preparation in high-shear mixer of sustained-release pellets by melt pelletisation

scientific article published on 01 August 2000

Prolonged prostaglandin E1 therapy in a neonate with pulmonary atresia and ventricular septal defect and the development of antral foveolar hyperplasia and hypertrophic pyloric stenosis

scientific article published on 22 March 2013

Prolonged subcutaneous delivery of low molecular weight heparin based on thermoresponsive hydrogels with chitosan nanocomplexes: Design, in vitro evaluation, and cytotoxicity studies

scientific article published on 23 April 2015

Quality improvement of melt extruded laminar systems using mixture design.

scientific article published on 23 April 2015

Rapid high-performance liquid chromatography method for determination of pregabalin in a pharmaceutical dosage form following derivatization with fluorescamine

scientific article published on July 1, 2010

Rationale of using Vinca minor Linne dry extract phytocomplex as a vincamine's oral bioavailability enhancer.

scientific article published on 11 December 2012

Relationship of the reduced folate carrier gene polymorphism G80A to methotrexate plasma concentration, toxicity, and disease outcome in childhood acute lymphoblastic leukemia.

scientific article published in April 2010

Role of anticonvulsant therapeutic drug monitoring in improving clinical outcomes: An example of 12 adult epilepsy patients

Simple and sensitive high performance liquid chromatography method with fluorescence detection for therapeutic drug monitoring of topiramate

scientific article published in January 2015

Simultaneous determination of gabapentin, pregabalin, vigabatrin, and topiramate in plasma by HPLC with fluorescence detection

scientific article published on 23 May 2014

Simultaneous determination of risperidone and 9-hydroxyrisperidone enantiomers in human blood plasma by liquid chromatography with electrochemical detection.

scientific article published on 16 June 2009

The Correlation between Zeta Potential and Mucoadhesion Strength on Pig Vesical Mucosa ⬇️

scientific article published on May 1, 2003

The Role of Reactive Species in Epileptogenesis and Influence of Antiepileptic Drug Therapy on Oxidative Stress ⬇️

scientific article published on December 1, 2012

The impact of FcγRIIa and FcγRIIIa gene polymorphisms on responses to RCHOP chemotherapy in diffuse large B-cell lymphoma patients

scientific article published on April 2016

The influence of co-treatment with carbamazepine, amiodarone and statins on warfarin metabolism and maintenance dose

scientific article published on 22 March 2006

The influence of drug-drug interaction and patients' characteristics on valproic acid's clearance in adults with epilepsy using nonlinear mixed effects modeling.

scientific article published on 3 October 2009

The role of pharmacokinetic modelling and computer simulation in drug formulation design

scientific article published on 01 July 1998

The study of drug release from microspheres adhered on pig vesical mucosa

scientific article published in August 2001

Thematic issue on drug delivery for specific populations.

scientific article published on 23 April 2015

Thermoreversible in situ gelling poloxamer-based systems with chitosan nanocomplexes for prolonged subcutaneous delivery of heparin: design and in vitro evaluation

scientific article published on 21 March 2013

Vitamin E and essential polyunsaturated fatty acids supplementation in schizophrenia patients treated with haloperidol

scientific article published on 24 July 2014

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