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List of works by Seamus Martin

50 years of The FEBS Journal: looking back as well as ahead.

scientific article published in December 2017

A Guide to 'A Guide to….' articles, some thoughts on impact, and why you really should publish with The FEBS Journal

scientific article published on 01 July 2018

A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence

scientific article

A perspective on mammalian caspases as positive and negative regulators of inflammation

scientific article published on May 2012

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

scientific article published on July 1996

An Apollon vista of death and destruction

scientific article published on 01 September 2004

An ERK-dependent pathway to Noxa expression regulates apoptosis by platinum-based chemotherapeutic drugs.

scientific article published on 30 August 2010

An Inflammatory Perspective on Necroptosis

scientific article published on March 2017

Analysis of apoptosis in cell-free systems

scientific article published on March 2008

Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes

scientific article

Apoptosis and cancer: the failure of controls on cell death and cell survival.

scientific article

Apoptosis as a goal of cancer therapy

scientific article published on November 1994

Apoptosis: Suicide,execution or murder?

scientific article published on 01 May 1993

Apoptosis: calling time on apoptosome activity

scientific article published on 6 October 2009

Apoptosis: controlled demolition at the cellular level

scientific article (publication date: March 2008)

Apoptosomes: protease activation platforms to die from

scientific article

Apoptotic cell death in disease—Current understanding of the NCCD 2023

scientific article published in 2023

Autophagy in Multiple Myeloma: What Makes You Stronger Can Also Kill You

scientific article published on 01 April 2013

Autophagy in malignant transformation and cancer progression

scientific article

Autosis: a new addition to the cell death Tower of Babel

scientific article published on 10 July 2014

Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release

scientific article

Bcl-2 family proteins and mitochondrial fission/fusion dynamics

scientific article published on 09 February 2010

Bcl-2 family proteins participate in mitochondrial quality control by regulating Parkin/PINK1-dependent mitophagy

scientific article published on 3 July 2014

Bicaudal is a conserved substrate for Drosophila and mammalian caspases and is essential for cell survival

scientific article

CARD games in apoptosis and immunity

scientific article

CARDINAL roles in apoptosis and NFkappaB activation

scientific article published on January 2004

CELL BIOLOGY: Double Knockout Blow for Caspases

scientific article published in Science

Caspase activation cascades in apoptosis

scientific article published on 01 February 2008

Caspase activation pathways: some recent progress

scientific article published on 01 July 2009

Caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling

scientific article published on 12 April 2010

Caspase-1 promiscuity is counterbalanced by rapid inactivation of processed enzyme

scientific article published on 11 July 2011

Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory "FADDosome" Complex upon TRAIL Stimulation

scientific article published in February 2017

Caspase-activation pathways in apoptosis and immunity

scientific journal article

Caspase-dependent inactivation of proteasome function during programmed cell death in Drosophila and man.

scientific article published on 21 June 2004

Caspase-independent cell death

scientific article

Caspases: Agents of Defense and Destruction

Caspases: cellular demolition experts

scientific article published on November 1, 2001

Cell death and inflammation: the case for IL-1 family cytokines as the canonical DAMPs of the immune system

scientific article published on 7 June 2016

Cell stress-associated caspase activation: intrinsically complex?

scientific article

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

scientific article published in February 1995

Commitment in apoptosis: slightly dead but mostly alive

scientific article published on 04 July 2008

Competition for growth factors: a lot more death with a little less Aktion.

scientific article published on October 2013

Concurrent MEK and autophagy inhibition is required to restore cell death associated danger-signalling in Vemurafenib-resistant melanoma cells

scientific article published on 18 December 2014

Correction: Bicaudal Is a Conserved Substrate for Drosophila and Mammalian Caspases and Is Essential for Cell Survival

scientific article published on 31 March 2009

Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system.

scientific article

Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B.

scientific article

Dealing the CARDs between life and death

scientific article published on 01 May 2001

Defying death: showing Bcl-2 the way home

scientific article

Degradation of retinoblastoma protein in tumor necrosis factor- and CD95-induced cell death.

scientific article published on April 1997

Destabilizing influences in apoptosis: sowing the seeds of IAP destruction

scientific article

Dicing with death: dissecting the components of the apoptosis machinery.

scientific article

Distinguishing between apoptosis, necrosis, necroptosis and other cell death modalities

scientific article published in June 2013

Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis

scientific article published on 28 May 2015

Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli.

scientific article

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl ⬇️

scientific article published on November 1, 1995

Emerging role for members of the Bcl-2 family in mitochondrial morphogenesis

scientific article

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

scientific article

Establishing a Blueprint for CED-3-dependent Killing through Identification of Multiple Substrates for This Protease

scientific article published in Journal of Biological Chemistry

Executioner caspase-3 and caspase-7 are functionally distinct proteases

scholarly article

Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis.

scientific article published on 31 October 2000

Expression and purification of recombinant annexin V for the detection of membrane alterations on apoptotic cells

scientific article published on March 2008

Expression, purification and use of recombinant annexin V for the detection of apoptotic cells

scientific article published on 3 September 2009

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing

scientific article published on 01 March 2018

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

scientific article published in April 1995

Failure of Bcl-2 to block cytochrome c redistribution during TRAIL-induced apoptosis

scientific article published on 01 April 2000

Fas and TRAIL 'death receptors' as initiators of inflammation: Implications for cancer

scientific article published on 02 February 2015

Fas/CD95-induced chemokines can serve as "find-me" signals for apoptotic cells

scientific article

Getting a gRIP on Flu by Casting the DAI.

scientific article

Getting the measure of apoptosis

scientific article published on 01 March 2008

Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors

scientific article

Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α.

scientific article published on October 2011

Greasing the path to BAX/BAK activation

scientific article published in March 2012

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

scientific article published on 17 April 2009

How to prepare and deliver a great talk

scientific article published on 01 January 2019

Human and murine granzyme B exhibit divergent substrate preferences

scientific article

Identification of small-molecule elastase inhibitors as antagonists of IL-36 cytokine activation.

scientific article

Improvement by death in immunity

scientific article published on 01 February 2008

In vitro selectivity, in vivo biodistribution and tumour uptake of annexin V radiolabelled with a positron emitting radioisotope.

scientific article published on October 2003

Inflammatory outcomes of apoptosis, necrosis and necroptosis

scientific article

Inhibition of TNF-induced apoptosis by NF-κB ⬇️

scientific article published on March 1, 1998

Inhibitor of apoptosis proteins (IAPs) and their antagonists regulate spontaneous and tumor necrosis factor (TNF)-induced proinflammatory cytokine and chemokine production

scientific article

Interchain proteolysis, in the absence of a dimerization stimulus, can initiate apoptosis-associated caspase-8 activation

scientific article

Iodine-124 labelled annexin-V as a potential radiotracer to study apoptosis using positron emission tomography

scientific article

John Hardy is the UK's first Breakthrough Prize laureate.

scientific article published on 17 November 2015

Measuring Apoptosis by Microscopy and Flow Cytometry.

scientific article published on 2 February 2016

Measuring apoptosis by microscopy and flow cytometry

scientific article published on 9 February 2013

Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential

scientific article published in April 2018

Mitochondrial Fusion: Bax to the Fussure ⬇️

scientific article published on February 15, 2011

Mitochondrial fission/fusion dynamics and apoptosis

scientific article published on 18 August 2010

Mitochondrial membrane remodeling in apoptosis: an inside story.

scientific article published on 13 October 2006

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B.

scientific article

Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production

scientific article published on 23 January 2015

Neutrophil extracellular traps can serve as platforms for processing and activation of IL-1 family cytokines

scientific article published on 4 April 2017

Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines

scientific article published on 13 January 2016

Nucleophosmin is cleaved and inactivated by the cytotoxic granule protease granzyme M during natural killer cell-mediated killing

scientific article published on 22 December 2008

Oncogene-induced autophagy and the Goldilocks principle ⬇️

scientific article published on August 1, 2011

Oncogenic B-RafV600E inhibits apoptosis and promotes ERK-dependent inactivation of Bad and Bim.

scientific article

Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival

scientific article published on 25 February 2011

Opening the Cellular Poison Cabinet

scientific article published in Science

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

scientific article

PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

scientific article

Parkin sensitizes toward apoptosis induced by mitochondrial depolarization through promoting degradation of Mcl-1.

scientific article

Partial cleavage of RasGAP by caspases is required for cell survival in mild stress conditions

scientific article

Portrait of a killer: the mitochondrial apoptosome emerges from the shadows

scientific article published on February 2003

Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex

scientific article

Production of biologically active IL-36 family cytokines through insertion of N-terminal caspase cleavage motifs

scientific article

Programmed cell death (apoptosis) in lymphoid and myeloid cell lines during zinc deficiency

scientific article published on 01 February 1991

Protease activation during apoptosis: death by a thousand cuts?

scientific article published on August 1995

Proteases, proteasomes and apoptosis: breaking Ub is hard to do.

scientific article published in September 2005

Protein or RNA synthesis inhibition induces apoptosis of mature human CD4+ T cell blasts

scientific article published on 01 February 1993

Proteolysis of fodrin (non-erythroid spectrin) during apoptosis.

scientific article published on March 1995

Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme

scientific article

Proteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery.

scientific article published on 7 December 2017

RIPK1 can function as an inhibitor rather than an initiator of RIPK3-dependent necroptosis

scientific article published on 4 October 2014

Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics

scientific article published on March 2006

Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins

scientific article published on 12 April 2004

Special Issue on Cell Death: Murder, mystery (and a little bit of mayhem) in Manhattan

scientific article

Staying Alive: Defensive Strategies in the BCL-2 Family Playbook

scientific article published on 01 November 2011

Suppressing IL-36-driven inflammation using peptide pseudosubstrates for neutrophil proteases

scientific article published on 7 March 2018

Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases.

scientific article

TRAIL Receptors Serve as Stress-Associated Molecular Patterns to Promote ER-Stress-Induced Inflammation

scientific article published on 27 February 2020

The FEBS Journal in 2015: onwards and upwards

scientific article published in 2014

The FEBS Journal in 2016: read, reflect and don't feed the wolves.

scientific article published on 10 December 2015

The FEBS Journal in 2018 - putting a bit of color in your life, and your figures

scientific article published in January 2018

The FEBS Journal in 2019: ensuring that casks of vintage wine remain unspoiled

scientific article published on 01 January 2019

The FEBS Journal in 2020: Open Access and quality versus quantity publishing

scientific article published on 01 January 2020

The FEBS Journal in 2021: a sharp reminder that science really matters

scientific article published on 01 January 2021

The FEBS Journal: passing the editorial baton

scientific article published in 2013

The FEBS Journalin 2017: quality is its own reward

scientific article published on 01 January 2017

The apoptosome pathway to caspase activation in primary human neutrophils exhibits dramatically reduced requirements for cytochrome C

scientific article published on March 2003

The cytotoxic lymphocyte protease, granzyme B, targets the cytoskeleton and perturbs microtubule polymerization dynamics

scientific article published on 16 January 2006

The killer and the executioner: how apoptosis controls malignancy.

scientific article published on October 1995

The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

scientific article

To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps

scientific article published on 08 January 2019

Two-dimensional gel-based analysis of the demolition phase of apoptosis

scientific article

Words of Advice: for what it's worth, our tuppenceworth.

scientific article published in November 2016

Writing a successful fellowship or grant application.

scientific article published in November 2017

c-Myc: where death and division collide

scientific article published in April 2004

iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.

scientific article published on 13 June 2018

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