List of works - Marcel V. Alavi

A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16.

scientific article published on 24 February 2011

A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics ⬇️

scientific article published on December 8, 2011

A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy.

scientific article published on 21 February 2007

Aging and Vision

scientific article published on 01 January 2016

Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress.

scientific article

Altered skeletal muscle mitochondrial biogenesis but improved endurance capacity in trained OPA1-deficient mice

scientific article

Col4a1 mutations cause progressive retinal neovascular defects and retinopathy

scientific article (publication date: 2016)

Dominant optic atrophy, OPA1, and mitochondrial quality control: understanding mitochondrial network dynamics

scientific article

Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload.

scientific article published on 08 March 2012

Electrophysiological and histologic assessment of retinal ganglion cell fate in a mouse model for OPA1-associated autosomal dominant optic atrophy

scientific article published on 15 October 2009

Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse.

scientific article

Genomic rearrangements in OPA1 are frequent in patients with autosomal dominant optic atrophy.

scientific article

Identification of genes that are linked with optineurin expression using a combined RNAi--microarray approach

scientific article

In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse

scientific article

Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.

scientific article

Long-term photoreceptor rescue in two rodent models of retinitis pigmentosa by adeno-associated virus delivery of Stanniocalcin-1.

scientific article published on 30 September 2017

OMA1-An integral membrane protease?

scientific article published on 29 October 2020

Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy.

scientific article

Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice.

scientific article

Subtle neurological and metabolic abnormalities in an Opa1 mouse model of autosomal dominant optic atrophy

scientific article published on 6 October 2009

Targeted OMA1 therapies for cancer

scientific article published on 21 February 2019

The protein translocon of the plastid envelopes

scientific article published on 21 March 2004

Type IV Collagens and Basement Membrane Diseases: Cell Biology and Pathogenic Mechanisms

scientific article published on 20 October 2015

List of works by Marcel V. Alavi

A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16.

A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics ⬇️

A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy.

Aging and Vision

Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress.

Altered skeletal muscle mitochondrial biogenesis but improved endurance capacity in trained OPA1-deficient mice

Col4a1 mutations cause progressive retinal neovascular defects and retinopathy

Dominant optic atrophy, OPA1, and mitochondrial quality control: understanding mitochondrial network dynamics

Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload.

Electrophysiological and histologic assessment of retinal ganglion cell fate in a mouse model for OPA1-associated autosomal dominant optic atrophy

Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse.

Genomic rearrangements in OPA1 are frequent in patients with autosomal dominant optic atrophy.

Identification of genes that are linked with optineurin expression using a combined RNAi--microarray approach

In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse

Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.

Long-term photoreceptor rescue in two rodent models of retinitis pigmentosa by adeno-associated virus delivery of Stanniocalcin-1.

OMA1-An integral membrane protease?

Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy.

Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice.

Subtle neurological and metabolic abnormalities in an Opa1 mouse model of autosomal dominant optic atrophy

Targeted OMA1 therapies for cancer

The protein translocon of the plastid envelopes

Type IV Collagens and Basement Membrane Diseases: Cell Biology and Pathogenic Mechanisms