List of works - Päivi Tammela

2-Aminopyridine Analogs Inhibit Both Enzymes of the Glyoxylate Shunt in Pseudomonas aeruginosa

scientific article published on 03 April 2020

A New Cell-Based AI-2-Mediated Quorum Sensing Interference Assay in Screening of LsrK-Targeted Inhibitors

scientific article published on 06 February 2020

A Versatile Strategy for the Synthesis of 4,5-Dihydroxy-2,3-Pentanedione (DPD) and Related Compounds as Potential Modulators of Bacterial Quorum Sensing

scientific article published on 6 October 2018

A rapid screening method for detecting active compounds against erythromycin-resistant bacterial strains of Finnish origin

scientific article published on 01 January 2005

Acetate-Derived Metabolites from the Brown Alga Lobophora variegata.

scientific article

Aggregating behavior of phenolic compounds--a source of false bioassay results?

scientific article published on 7 September 2012

Aging in Pinus sylvestris L. seeds: changes in viability and lipids

scientific article published on 01 December 2000

An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors

scientific article published on 10 February 2019

Analyzing user-generated online content for drug discovery: development and use of MedCrawler.

scientific article published on 22 December 2016

Antibacterial profiling of abietane-type diterpenoids.

scientific article

Antidepressant drugs transactivate TrkB neurotrophin receptors in the adult rodent brain independently of BDNF and monoamine transporter blockade

scientific article published in 2011

Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues

scientific article published on 14 February 2014

Betulin-derived compounds as inhibitors of alphavirus replication

scientific article published in November 2009

Bioactive cembrane derivatives from the Indian Ocean soft coral, Sinularia kavarattiensis

scientific article

Bioluminescent whole-cell reporter gene assays as screening tools in the identification of antimicrobial natural product extracts.

scientific article published on 30 April 2015

Cell-based bioreporter assay coupled to HPLC micro-fractionation in the evaluation of antimicrobial properties of the basidiomycete fungus Pycnoporus cinnabarinus

scientific article published on 25 January 2016

Comparison of transgenic Gerbera hybrida lines and traditional varieties shows no differences in cytotoxicity or metabolic fingerprints

scientific article published on 30 January 2008

DPD-Inspired Discovery of Novel LsrK Kinase Inhibitors: An Opportunity To Fight Antimicrobial Resistance

scientific article published on 04 March 2019

Defining conditions for biofilm inhibition and eradication assays for Gram-positive clinical reference strains

scientific article published in 2018

Design, Synthesis, and Evaluation of Novel Tyrosine-Based DNA Gyrase B Inhibitors.

scientific article published on 16 June 2017

Design, synthesis and biological evaluation of 4,5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors.

scientific article

Design, synthesis and biological evaluation of novel DNA gyrase inhibitors and their siderophore mimic conjugates

scientific article published on 23 December 2019

Design, synthesis, and biological evaluation of 1-ethyl-3-(thiazol-2-yl)urea derivatives as Escherichia coli DNA gyrase inhibitors.

scientific article published on 14 December 2017

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

scientific article published on 8 July 2015

Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors

scientific article

Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors.

scientific article published on 22 February 2017

Effect of Hybrid Type and Harvesting Season on Phytochemistry and Antibacterial Activity of Extracted Metabolites from <i>Salix</i> Bark

scientific article published in 2022

Effect of pmt gene overexpression on tropane alkaloid production in transformed root cultures of Datura metel and Hyoscyamus muticus

scientific article

Effects of extracts of commonly consumed food supplements and food fractions on the permeability of drugs across Caco-2 cell monolayers

scientific article published in October 2004

Effects of the aqueous extract of Bryothamnion triquetrum on chemical hypoxia and aglycemia-induced damage in GT1-7 mouse hypothalamic immortalized cells.

scientific article published on 29 June 2005

Exploring marine resources for bioactive compounds.

scientific article

Exploring the structure-activity relationships of ABCC2 modulators using a screening approach

scientific article published on 17 April 2015

Fabrication of concave micromirrors for single cell imaging via controlled over-exposure of organically modified ceramics in single step lithography

scientific article published in May 2017

Identification and Characterization of Approved Drugs and Drug-Like Compounds as Covalent Escherichia coli ClpP Inhibitors

scientific article published on 31 May 2019

Identification of Alphavirus Inhibitors by Using Virus-Based Assays and a Chikungunya Replicon Cell Line

scientific article published in 2011

In vitro assay for human toxicity of cereulide, the emetic mitochondrial toxin produced by food poisoning Bacillus cereus

article

In-vitro mutagenic potential and effect on permeability of co-administered drugs across Caco-2 cell monolayers of Rubus idaeus and its fortified fractions.

scientific article published in November 2006

Inhibition of Breast Cancer Resistance Protein and Multidrug Resistance Associated Protein 2 by Natural Compounds and Their Derivatives

scientific article

Inhibition of Hepatitis C Replication by Targeting the Molecular Chaperone Hsp90: Synthesis and Biological Evaluation of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazole Derivatives

scientific article published on 22 January 2019

Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays

scientific article

Inhibitory effect of dietary phenolic compounds on Chlamydia pneumoniae in cell cultures.

scientific article published on 18 January 2006

Integrated in vitro-in silico screening strategy for the discovery of antibacterial compounds.

scientific article published on January 2015

Marine Microalgae: Promising Source for New Bioactive Compounds

scientific article published on 06 September 2018

Marine alkaloid oroidin analogues with antiviral potential: A novel class of synthetic compounds targeting the cellular chaperone Hsp90.

scientific article published on 5 June 2017

Miniaturisation and validation of a cell-based assay for screening of Ca2+ channel modulators.

scientific article published on June 2004

N-Phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation

scientific article

Nanofibrillar cellulose wound dressing in skin graft donor site treatment

scientific article published on August 2016

New N-phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATPase inhibitors of DNA gyrase

scientific article

New N-phenyl-4,5-dibromopyrrolamides as DNA gyrase B inhibitors

scientific article published on 20 May 2019

New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity

scientific article published on 10 May 2018

Permeability characteristics and membrane affinity of flavonoids and alkyl gallates in Caco-2 cells and in phospholipid vesicles

scientific article published in May 2004

Pumilol, a Diterpenoid with a Rare Strobane Skeleton from Pinus pumila (Pinaceae)

scientific article published on 03 September 2018

Screening and characterisation of antimicrobial properties of semisynthetic betulin derivatives

scientific article (publication date: 2014)

Screening bioactivity and bioactive constituents of Nordic unifloral honeys

scientific article published on 18 May 2017

Screening_mgmt: a Python module for managing screening data

scientific article published on 7 November 2014

Second-generation 4,5,6,7-tetrahydrobenzo[d]thiazoles as novel DNA gyrase inhibitors

scientific article published on 11 February 2020

Structure-Based Virtual Screening of LsrK Kinase Inhibitors to Target Quorum Sensing

scientific article published on 30 October 2018

Synthesis and Antiproliferative Activity of Marine Bromotyrosine Purpurealidin I and Its Derivatives

Synthesis and Biological Evaluation of 2-Aminobenzothiazole and Benzimidazole Analogs Based on the Clathrodin Structure

scientific article published on 28 December 2015

Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors

scientific article

Synthesis and biological evaluation of 2-arylbenzimidazoles targeting Leishmania donovani

scientific article

Synthesis and biological evaluation of crown ether acyl derivatives.

scientific article published on 29 September 2016

Targeting Quorum Sensing: High-Throughput Screening to Identify Novel LsrK Inhibitors

scientific article published on 25 June 2019

Utilization of in situ ELISA method for examining Trk receptor phosphorylation in cultured cells

scientific article

α-Amino Diphenyl Phosphonates as Novel Inhibitors of Escherichia coli ClpP Protease

scientific article published on 11 January 2019

γ-Aminobutyric acid type A (GABAA) receptor activation modulates tau phosphorylation.

scientific article

List of works by Päivi Tammela

2-Aminopyridine Analogs Inhibit Both Enzymes of the Glyoxylate Shunt in Pseudomonas aeruginosa

A New Cell-Based AI-2-Mediated Quorum Sensing Interference Assay in Screening of LsrK-Targeted Inhibitors

A Versatile Strategy for the Synthesis of 4,5-Dihydroxy-2,3-Pentanedione (DPD) and Related Compounds as Potential Modulators of Bacterial Quorum Sensing

A rapid screening method for detecting active compounds against erythromycin-resistant bacterial strains of Finnish origin

Acetate-Derived Metabolites from the Brown Alga Lobophora variegata.

Aggregating behavior of phenolic compounds--a source of false bioassay results?

Aging in Pinus sylvestris L. seeds: changes in viability and lipids

An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors

Analyzing user-generated online content for drug discovery: development and use of MedCrawler.

Antibacterial profiling of abietane-type diterpenoids.

Antidepressant drugs transactivate TrkB neurotrophin receptors in the adult rodent brain independently of BDNF and monoamine transporter blockade

Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues

Betulin-derived compounds as inhibitors of alphavirus replication

Bioactive cembrane derivatives from the Indian Ocean soft coral, Sinularia kavarattiensis

Bioluminescent whole-cell reporter gene assays as screening tools in the identification of antimicrobial natural product extracts.

Cell-based bioreporter assay coupled to HPLC micro-fractionation in the evaluation of antimicrobial properties of the basidiomycete fungus Pycnoporus cinnabarinus

Comparison of transgenic Gerbera hybrida lines and traditional varieties shows no differences in cytotoxicity or metabolic fingerprints

DPD-Inspired Discovery of Novel LsrK Kinase Inhibitors: An Opportunity To Fight Antimicrobial Resistance

Defining conditions for biofilm inhibition and eradication assays for Gram-positive clinical reference strains

Design, Synthesis, and Evaluation of Novel Tyrosine-Based DNA Gyrase B Inhibitors.

Design, synthesis and biological evaluation of 4,5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors.

Design, synthesis and biological evaluation of novel DNA gyrase inhibitors and their siderophore mimic conjugates

Design, synthesis, and biological evaluation of 1-ethyl-3-(thiazol-2-yl)urea derivatives as Escherichia coli DNA gyrase inhibitors.

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors

Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors.

Effect of Hybrid Type and Harvesting Season on Phytochemistry and Antibacterial Activity of Extracted Metabolites from <i>Salix</i> Bark

Effect of pmt gene overexpression on tropane alkaloid production in transformed root cultures of Datura metel and Hyoscyamus muticus

Effects of extracts of commonly consumed food supplements and food fractions on the permeability of drugs across Caco-2 cell monolayers

Effects of the aqueous extract of Bryothamnion triquetrum on chemical hypoxia and aglycemia-induced damage in GT1-7 mouse hypothalamic immortalized cells.

Exploring marine resources for bioactive compounds.

Exploring the structure-activity relationships of ABCC2 modulators using a screening approach

Fabrication of concave micromirrors for single cell imaging via controlled over-exposure of organically modified ceramics in single step lithography

Identification and Characterization of Approved Drugs and Drug-Like Compounds as Covalent Escherichia coli ClpP Inhibitors

Identification of Alphavirus Inhibitors by Using Virus-Based Assays and a Chikungunya Replicon Cell Line

In vitro assay for human toxicity of cereulide, the emetic mitochondrial toxin produced by food poisoning Bacillus cereus

In-vitro mutagenic potential and effect on permeability of co-administered drugs across Caco-2 cell monolayers of Rubus idaeus and its fortified fractions.

Inhibition of Breast Cancer Resistance Protein and Multidrug Resistance Associated Protein 2 by Natural Compounds and Their Derivatives

Inhibition of Hepatitis C Replication by Targeting the Molecular Chaperone Hsp90: Synthesis and Biological Evaluation of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazole Derivatives

Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays

Inhibitory effect of dietary phenolic compounds on Chlamydia pneumoniae in cell cultures.

Integrated in vitro-in silico screening strategy for the discovery of antibacterial compounds.

Marine Microalgae: Promising Source for New Bioactive Compounds

Marine alkaloid oroidin analogues with antiviral potential: A novel class of synthetic compounds targeting the cellular chaperone Hsp90.

Miniaturisation and validation of a cell-based assay for screening of Ca2+ channel modulators.

N-Phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation

Nanofibrillar cellulose wound dressing in skin graft donor site treatment

New N-phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATPase inhibitors of DNA gyrase

New N-phenyl-4,5-dibromopyrrolamides as DNA gyrase B inhibitors

New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity

Permeability characteristics and membrane affinity of flavonoids and alkyl gallates in Caco-2 cells and in phospholipid vesicles

Pumilol, a Diterpenoid with a Rare Strobane Skeleton from Pinus pumila (Pinaceae)

Screening and characterisation of antimicrobial properties of semisynthetic betulin derivatives

Screening bioactivity and bioactive constituents of Nordic unifloral honeys

Screening_mgmt: a Python module for managing screening data

Second-generation 4,5,6,7-tetrahydrobenzo[d]thiazoles as novel DNA gyrase inhibitors

Structure-Based Virtual Screening of LsrK Kinase Inhibitors to Target Quorum Sensing

Synthesis and Antiproliferative Activity of Marine Bromotyrosine Purpurealidin I and Its Derivatives

Synthesis and Biological Evaluation of 2-Aminobenzothiazole and Benzimidazole Analogs Based on the Clathrodin Structure

Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors

Synthesis and biological evaluation of 2-arylbenzimidazoles targeting Leishmania donovani

Synthesis and biological evaluation of crown ether acyl derivatives.

Targeting Quorum Sensing: High-Throughput Screening to Identify Novel LsrK Inhibitors

Utilization of in situ ELISA method for examining Trk receptor phosphorylation in cultured cells

α-Amino Diphenyl Phosphonates as Novel Inhibitors of Escherichia coli ClpP Protease

γ-Aminobutyric acid type A (GABAA) receptor activation modulates tau phosphorylation.