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List of works by Amr S Abu Lila

A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics

scientific article published on 02 October 2018

A Novel Platform for Cancer Vaccines: Antigen-Selective Delivery to Splenic Marginal Zone B Cells via Repeated Injections of PEGylated Liposomes

scientific article published on 17 October 2018

A Novel Strategy to Increase the Yield of Exosomes (Extracellular Vesicles) for an Expansion of Basic Research

scientific article published on 01 January 2018

A double-modulation strategy in cancer treatment with a chemotherapeutic agent and siRNA.

scientific article

A hydroxyl PEG version of PEGylated liposomes and its impact on anti-PEG IgM induction and on the accelerated clearance of PEGylated liposomes

scientific article published on 17 February 2018

A simplified method for manufacturing RNAi therapeutics for local administration

scientific article published on 20 April 2019

Abrogation of the accelerated blood clearance phenomenon by SOXL regimen: promise for clinical application

scientific article published on 19 November 2012

Activation of TLR9 by incorporated pDNA within PEG-coated lipoplex enhances anti-PEG IgM production

scientific article published on 3 April 2014

Advanced therapeutic approach for the treatment of malignant pleural mesothelioma via the intrapleural administration of liposomal pemetrexed.

scientific article published on 14 October 2015

Anti-PEG IgM Production via a PEGylated Nanocarrier System for Nucleic Acid Delivery

scientific article published on 01 January 2019

Application of polyglycerol coating to plasmid DNA lipoplex for the evasion of the accelerated blood clearance phenomenon in nucleic acid delivery.

scientific article published on 17 December 2013

B cell-intrinsic toll-like receptor 7 is responsible for the enhanced anti-PEG IgM production following injection of siRNA-containing PEGylated lipoplex in mice.

scientific article published on 13 April 2014

Co-administration of liposomal l-OHP and PEGylated TS shRNA-lipoplex: A novel approach to enhance anti-tumor efficacy and reduce the immunogenic response to RNAi molecules

scientific article published on 28 April 2017

Combination therapy with metronomic S-1 dosing and oxaliplatin-containing PEG-coated cationic liposomes in a murine colorectal tumor model: synergy or antagonism?

scientific article published on 30 January 2012

Downregulation of thymidylate synthase by RNAi molecules enhances the antitumor effect of pemetrexed in an orthotopic malignant mesothelioma xenograft mouse model.

scientific article published on February 2016

Doxorubicin Expands in Vivo Secretion of Circulating Exosome in Mice

scientific article published on 01 January 2018

Encapsulation in a rapid-release liposomal formulation enhances the anti-tumor efficacy of pemetrexed in a murine solid mesothelioma-xenograft model

scientific article published on 25 September 2015

Ex-vivo/in-vitro anti-polyethylene glycol (PEG) immunoglobulin M production from murine splenic B cells stimulated by PEGylated liposome.

scientific article

Ganglioside inserted into PEGylated liposome attenuates anti-PEG immunity.

scientific article published on 5 February 2017

Generation, characterization and in vivo biological activity of two distinct monoclonal anti-PEG IgMs

scientific article published on 12 March 2014

Improved intratumoral delivery of PEG-coated siRNA-lipoplexes by combination with metronomic S-1 dosing in a murine solid tumor model

scientific article published on 01 April 2012

Improvement of intratumor microdistribution of PEGylated liposome via tumor priming by metronomic S-1 dosing.

scientific article published on 25 October 2016

Intra-tumor distribution of PEGylated liposome upon repeated injection: No possession by prior dose.

scientific article published on 5 November 2015

Intratumoral Visualization of Oxaliplatin within a Liposomal Formulation Using X-ray Fluorescence Spectrometry

scientific article published on 29 December 2017

Liposome co-incubation with cancer cells secreted exosomes (extracellular vesicles) with different proteins expressions and different uptake pathways

scientific article published in Scientific Reports

Metronomic S-1 dosing and thymidylate synthase silencing have synergistic antitumor efficacy in a colorectal cancer xenograft model

scientific article published on 9 November 2016

Metronomic chemotherapy and nanocarrier platforms.

scientific article published on 9 November 2016

Modulation of Drug Release from Natural Polymer Matrices by Response Surface Methodology: in vitro and in vivo Evaluation

scientific article published on 01 December 2020

Modulation of antitumor immunity contributes to the enhanced therapeutic efficacy of liposomal oxaliplatin in mouse model.

scientific article published on 23 June 2017

Multiple administration of PEG-coated liposomal oxaliplatin enhances its therapeutic efficacy: A possible mechanism and the potential for clinical application ⬇️

scientific article published on August 24, 2012

Oxaliplatin encapsulated in PEG-coated cationic liposomes induces significant tumor growth suppression via a dual-targeting approach in a murine solid tumor model

scientific article published on 12 March 2009

Oxaliplatin targeting to angiogenic vessels by PEGylated cationic liposomes suppresses the angiogenesis in a dorsal air sac mouse model.

scientific article

PEGylated liposomes: immunological responses

scientific article published on 26 June 2019

Preparation and characterization of intravaginal vardenafil suppositories targeting a complementary treatment to boost in vitro fertilization process.

scientific article published on 27 September 2017

Reactivity of IgM antibodies elicited by PEGylated liposomes or PEGylated lipoplexes against auto and foreign antigens.

scientific article

Recent advances in tumor vasculature targeting using liposomal drug delivery systems.

scientific article published on December 2009

Sequential administration with oxaliplatin-containing PEG-coated cationic liposomes promotes a significant delivery of subsequent dose into murine solid tumor

scientific article published on 25 October 2009

Sequential treatment of oxaliplatin-containing PEGylated liposome together with S-1 improves intratumor distribution of subsequent doses of oxaliplatin-containing PEGylated liposome.

scientific article published on 17 December 2013

Systemically Administered RNAi Molecule Sensitizes Malignant Pleural Mesotheliomal Cells to Pemetrexed Therapy

scientific article published on 14 October 2016

Tailoring of Novel Bile Salt Stabilized Vesicles for Enhanced Transdermal Delivery of Simvastatin: A New Therapeutic Approach against Inflammation

scientific article published in 2023

Targeting anticancer drugs to tumor vasculature using cationic liposomes.

scientific article published on 24 March 2010

The accelerated blood clearance (ABC) phenomenon: clinical challenge and approaches to manage.

scientific article published on 07 August 2013

The co-delivery of oxaliplatin abrogates the immunogenic response to PEGylated siRNA-lipoplex

scientific article published on 15 May 2013

Therapeutic Applications of Biostable Silver Nanoparticles Synthesized Using Peel Extract of Benincasa hispida: Antibacterial and Anticancer Activities

scientific article published on 30 September 2020

Tumor-type-dependent vascular permeability constitutes a potential impediment to the therapeutic efficacy of liposomal oxaliplatin.

scientific article published on 25 April 2012

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