List of works - Wenhao Hu

A DFT calculation-inspired Rh(i)-catalyzed reaction via suppression of α-H shift in α-alkyldiazoacetates

scientific article published on 22 March 2017

A Diastereoselective Multicomponent Reaction for Construction of Alkynylamide-Substituted α,β-Diamino Acid Derivatives To Hunt Hits.

scientific article

A Rh(II)-catalyzed multicomponent reaction by trapping an α-amino enol intermediate in a traditional two-component reaction pathway.

scientific article published on 08 March 2017

A Rh(ii)-catalyzed three-component reaction of 3-diazooxindoles with N,N-disubstituted anilines and glyoxylates for the synthesis of 3-aryl-3-substituted oxindoles.

scientific article published on 12 October 2016

A facile access to polyfunctional oxygen-containing heterocycles via intramolecularly formed protic oxonium ylide trapping processes.

scientific article published on 6 November 2013

A facile three-component one-pot synthesis of structurally constrained tetrahydrofurans that are t-RNA synthetase inhibitor analogues.

scientific article

A highly diastereoselective three-component tandem 1,4-conjugated addition-cyclization reaction to multisubstituted pyrrolidines

scientific article published on 06 February 2012

A highly enantioselective four-component reaction for the efficient construction of chiral β-hydroxy-α-amino acid derivatives

scientific article published on 01 April 2013

A novel three-component reaction catalyzed by dirhodium(II) acetate: decomposition of phenyldiazoacetate with arylamine and imine for highly diastereoselective synthesis of 1,2-diamines

scientific article published on 01 October 2003

A strategy to synthesize taxol side chain and (-)-epi cytoxazone via chiral Brønsted acid-Rh(2)(OAc)(4) co-catalyzed enantioselective three-component reactions.

scientific article published on November 2010

An Isoform-Selective PTP1B Inhibitor Derived from Nitrogen-Atom Augmentation of Radicicol

scientific article published on 18 July 2019

An enantioselective three-component reaction of diazoacetates with indoles and enals by iridium/iminium co-catalysis.

scientific article published on 13 January 2016

An ylide transformation of rhodium(I) carbene: enantioselective three-component reaction through trapping of rhodium(I)-associated ammonium ylides by β-nitroacrylates

scientific article published on 05 October 2014

Asymmetric Counter-Anion-Directed Aminomethylation: Synthesis of Chiral β-Amino Acids via Trapping of an Enol Intermediate

scientific article published on 14 January 2019

Asymmetric Multicomponent Reactions Based on Trapping of Active Intermediates

scientific article published on 4 January 2017

Asymmetric Multicomponent Reactions for Efficient Construction of Homopropargyl Amine Carboxylic Esters

scientific article published on 01 July 2019

Bicyclic pyrazolidinone derivatives from diastereoselective catalytic [3 + 3]-cycloaddition reactions of enoldiazoacetates with azomethine imines.

scientific article published on 11 March 2013

Bond cleavage, fragment modification and reassembly in enantioselective three-component reactions

scientific article

Brønsted Acid Catalyzed Enantioselective Assembly of Spirochroman-3,3-oxindoles

scientific article published on 01 April 2020

Catalyst-Free Halogenation of α-Diazocarbonyl Compounds with N-Halosuccinimides: Synthesis of 3-Halooxindoles or Vinyl Halides.

scientific article published on 16 June 2016

Catalyst-Free gem-Difunctionalization of Fluoroalkyl-Substituted Diazo Compound with Diselenide or Disulfide and NFSI

scientific article published on 19 March 2019

Catalytic Asymmetric Four-Component Reaction for the Rapid Construction of 3,3-Disubstituted 3-Indol-3'-yloxindoles

scientific article published on 25 August 2015

Catalytic asymmetric functionalization of aromatic C-H bonds by electrophilic trapping of metal-carbene-induced zwitterionic intermediates.

scientific article

Catalytic enantioselective trapping of an alcoholic oxonium ylide with aldehydes: Rh(II)/Zr(IV)-co-catalyzed three-component reactions of aryl diazoacetates, benzyl alcohol, and aldehydes.

scientific article published in January 2008

Component match in rhodium catalyzed three-component reactions of ethyl diazoacetate, H2O and aryl imines: a highly diastereoselective one-step synthesis of beta-aryl isoserine derivatives.

scientific article published on 12 October 2009

Cooperative catalysis in highly enantioselective Mannich-type three-component reaction of a diazoacetophenone with an alcohol and an imine

scientific article published on 29 November 2010

Cooperative catalysis in multicomponent reactions: highly enantioselective synthesis of gamma-hydroxyketones with a quaternary carbon stereocenter

scientific article published on 01 March 2010

Copper(II)-catalyzed highly diastereoselective three-component reactions of aryl diazoacetates with alcohols and chalcones: an easy access to furan derivatives.

scientific article published in April 2010

Cu(I)-Catalyzed Three-Component Reaction of Diazo Compound with Terminal Alkyne and Nitrosobenzene for the Synthesis of Trifluoromethyl Dihydroisoxazoles

scientific article published on 27 July 2018

Cu(I)-Catalyzed Three-Component Reaction of α-Diazo Amide with Terminal Alkyne and Isatin Ketimine via Electrophilic Trapping of Active Alkynoate-Copper Intermediate

scientific article published on 03 June 2019

DNA binding ligands with in vivo efficacy in murine models of bacterial infection: optimization of internal aromatic amino acids

scientific article published on 01 May 2004

Deactivating Influence of 3-O-Glycosyl Substituent on Anomeric Reactivity of Thiomannoside Observed in Oligomannoside Synthesis.

scientific article published on 7 February 2017

Design, synthesis and antibacterial activity of 3-methylenepyrrolidine formyl hydroxyamino derivatives as novel peptide deformylase inhibitors

scientific article published on 30 November 2010

Design, synthesis, and antibacterial activity of 2,5-dihydropyrrole formyl hydroxyamino derivatives as novel peptide deformylase inhibitors.

scientific article published on 24 May 2010

Design, synthesis, and structure-activity relationship studies of novel fused heterocycles-linked triazoles with good activity and water solubility.

scientific article published on 7 March 2014

Diastereoselective three-component reactions of aryldiazoacetates with alcohols/water and alkynals: application to substituted enelactones

scientific article published on 28 March 2011

Diastereoselectively switchable enantioselective trapping of carbamate ammonium ylides with imines

scientific article published on 16 May 2011

Diastereoselectivity switch in cooperatively catalyzed three-component reactions of an aryldiazoacetate, an alcohol, and a β,γ-unsaturated α-keto ester

scientific article published on 13 June 2011

Dirhodium-catalyzed enantioselective C-H insertion of N-(2-benzyloxyethyl)-N-(tert-butyl)diazoacetamide and its application for the synthesis of chiral GABOB.

scientific article

Discovery of core-structurally novel PTP1B inhibitors with specific selectivity containing oxindole-fused spirotetrahydrofurochroman by one-pot reaction

scientific article published on 22 November 2016

Divergent Synthesis of Multisubstituted Tetrahydrofurans and Pyrrolidines via Intramolecular Aldol-type Trapping of Onium Ylide Intermediates.

scientific article published on 23 November 2015

Divergent outcomes of carbene transfer reactions from dirhodium- and copper-based catalysts separately or in combination

scientific article

Divergent synthesis of chiral heterocycles via sequencing of enantioselective three-component reactions and one-pot subsequent cyclization reactions

scientific article published on 13 April 2015

Diversity-oriented three-component reactions of diazo compounds with anilines and 4-oxo-enoates

scientific article published on 03 July 2013

Efficient synthesis of chiral cyclic acetals by metal and Brønsted acid co-catalyzed enantioselective four-component cascade reactions.

scientific article

Efficient synthesis of oxazoles by dirhodium(II)-catalyzed reactions of styryl diazoacetate with oximes.

scientific article published on December 2012

Efficient trapping of oxonium ylides with imines: a highly diastereoselective three-component reaction for the synthesis of beta-amino-alpha-hydroxyesters with quaternary stereocenters

scientific article published on 01 January 2007

Enantioselective Formal [3 + 1 + 1] Cycloaddition Reaction by Ru(II)/Iminium Cocatalysis for Construction of Multisubstituted Pyrrolidines.

scientific article published in March 2017

Enantioselective Multicomponent Reaction for Rapid Construction of 1,2,5-Triol Derivatives with Vicinal Chiral Centers.

scientific article published on 25 April 2017

Enantioselective Synthesis of α-Mercapto-β-amino Esters via Rh(II)/Chiral Phosphoric Acid-Cocatalyzed Three-Component Reaction of Diazo Compounds, Thiols, and Imines.

scientific article published on 22 November 2016

Enantioselective Trapping of Oxonium Ylides by 3-Hydroxyisoindolinones via a Formal SN1 Pathway for Construction of Contiguous Quaternary Stereocenters.

scientific article

Enantioselective oxidative functionalization of the Csp3-H bond adjacent to a nitrogen atom for rapid access to β-hydroxyl-α-amino acid derivatives

scientific article published in September 2016

Enantioselective palladium(II) phosphate catalyzed three-component reactions of pyrrole, diazoesters, and imines

scientific article published in December 2013

Enantioselective trapping of phosphoramidate ammonium ylides with imino esters for synthesis of 2,3-diaminosuccinic acid derivatives.

scientific article

Facile synthesis of 3-aryloxindoles via brønsted acid catalyzed Friedel-Crafts alkylation of electron-rich arenes with 3-diazooxindoles.

scientific article published on 15 May 2014

Gold(I)-Catalyzed and H2O-Mediated Carbene Cascade Reaction of Propargyl Diazoacetates: Furan Synthesis and Mechanistic Insights

scientific article published on 27 August 2018

Gold-Catalyzed 1,2-Acyloxy Migration/Coupling Cascade of Propargyl Diazoacetates: Synthesis of Isomycin Derivatives

scientific article published on 06 March 2019

Gold-Catalyzed Oxidative Cyclization/Aldol Addition of Homopropargyl Alcohols with Isatins

scientific article published on 31 December 2018

Green chemistry approaches to the regioselective synthesis of spiro heterobicyclic rings using iodine as a new and efficient catalyst under solvent-free conditions

scientific article published on 3 April 2010

Highly Enantioselective Three-Component Reactions of tert-Butyl Diazoacetate with Arylamines and Imines: An Efficient Synthesis of α,β-Bis(arylamino) Acid Derivatives

scholarly article by Wenhao Hu et al published 14 January 2013 in Synthesis

Highly chemoselective 2,4,5-triaryl-1,3-dioxolane formation from intermolecular 1,3-dipolar addition of carbonyl ylide with aryl aldehydes

scientific article published on 01 September 2004

Highly diastereoselective multicomponent cascade reactions: efficient synthesis of functionalized 1-indanols

scientific article published on 20 December 2012

Highly diastereoselective synthesis of 3-hydroxy-2,2,3-trisubstituted indolines via intramolecular trapping of ammonium ylides with ketones

scientific article published on 01 January 2014

Highly diastereoselective synthesis of fully substituted tetrahydrofurans by a one-pot cascade reaction of aryldiazoacetates with allyl alcohols.

scientific article published in November 2009

Highly efficient synthesis of mixed 3,3'-bisindoles via Rh(II)-catalyzed three-component reaction of 3-diazooxindoles with indoles and ethyl glyoxylate

scientific article published on 28 June 2013

Highly enantioselective catalytic synthesis of functionalized chiral diazoacetoacetates

scientific article

Highly enantioselective trapping of zwitterionic intermediates by imines

scientific article published on 29 July 2012

In search of high stereocontrol for the construction of cis-disubstituted cyclopropane compounds. Total synthesis of a cyclopropane-configured urea-PETT analogue that is a HIV-1 reverse transcriptase inhibitor

scientific article published on 01 March 2002

Iron catalyzed efficient synthesis of poly-functional primary amines via the direct use of ammonia.

scientific article published on 20 February 2017

Iron porphyrin-catalyzed three-component reaction of ethyl diazoacetate with aliphatic amines and β,γ-unsaturated α-keto esters.

scientific article published on 19 November 2013

Novel C-C bond formation through addition of ammonium ylides to arylaldehydes: a facile approach to beta-aryl-beta-hydroxy alpha-amino acid frameworks

scientific article published on 14 September 2004

Novel multicomponent reactions via trapping of protic onium ylides with electrophiles

scientific article published on 25 June 2013

Optimization of P2Y12 Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties

scientific article published on 19 March 2019

Pd(II)-catalyzed formal [4+1] cycloaddition reactions of diazoacetates and aryl propargyl alcohols to form 2,5-dihydrofurans

scientific article published on 2 September 2015

Pd(II)/β-ICD-Cocatalyzed Asymmetric Route to Oxindole Scaffold via Cascade Reaction of Diazoacetamides and MBH-Carbonates.

scientific article published on 26 August 2016

Privilege-Structure-Oriented Three-Component Asymmetric Aminomethylation: Assembly of Chiral 3-Aminomethyl Indolones

scientific article published on 03 December 2019

Protein Arginine Methyltransferase 5 (PRMT5) as an Anticancer Target and Its Inhibitor Discovery

scientific article published on 20 June 2018

Regio- and Diastereoselective Three-Component Reactions via Trapping of Ammonium Ylides with N-Alkylquinolinium Salts: Synthesis of Multisubstituted Tetra- and Dihydroquinoline Derivatives.

scientific article

Regio- and diastereoselective construction of α-hydroxy-δ-amino ester derivatives via 1,4-conjugate addition of β,γ-unsaturated N-sulfonylimines.

scientific article published on 15 April 2014

Rh(2)(OAc)(4)-AgOTf cooperative catalysis in cyclization/three-component reactions for concise synthesis of 1,2-dihydroisoquinolines.

scientific article published in February 2010

Rh(II)/Brønsted acid cocatalyzed intramolecular trapping of ammonium ylides with enones: diastereoselective synthesis of 2,2,3-trisubstituted indolines.

scientific article published on 15 August 2014

Rh(II)/Chiral Phosphoric Acid-Cocatalyzed Enantioselective Synthesis of Spirooxindole-Fused Thiaindans

scientific article published on 25 July 2018

Rhodium(II) catalyzed diastereoselective reactions of diazoacetamides with isatins: an efficient approach to 3-hydroxy-3,3'-bioxindoles

scientific article published on 01 November 2012

Rhodium(II)- and copper(II)-catalyzed reactions of enol diazoacetates with nitrones: metal carbene versus Lewis acid directed pathways.

scientific article

Rhodium-Catalyzed Formal C-O Insertion in Carbene/Alkyne Metathesis Reactions: Synthesis of 3-Substituted 3 H-Indol-3-ols

scientific article published on 23 May 2019

Rhodium-Catalyzed Nitrene/Alkyne Metathesis: An Enantioselective Process for the Synthesis of N-Heterocycles

scientific article published on 17 April 2019

Rhodium-catalyzed chemo- and regioselective cross-dimerization of two terminal alkynes.

scientific article published on 28 January 2013

Ruthenium(II)/chiral Brønsted acid co-catalyzed enantioselective four-component reaction/cascade aza-Michael addition for efficient construction of 1,3,4-tetrasubstituted tetrahydroisoquinolines.

scientific article

Ruthenium-Catalyzed Diastereoselective Synthesis of Fully Substituted Pyrrolidines from Anilines and Diazo Pyruvates

scientific article published on 01 April 2020

Selectivity control in enantioselective four-component reactions of aryl diazoacetates with alcohols, aldehydes and amines: an efficient approach to synthesizing chiral beta-amino-alpha-hydroxyesters

scientific article published on 11 November 2008

Small molecules enhance functional O-mannosylation of Alpha-dystroglycan.

scientific article published on 12 November 2015

Stereoselective synthesis of a sulfated tetrasaccharide corresponding to a rare sequence in the galactofucan isolated from Sargassum polycystum

scientific article published on 2 May 2014

Stereoselective synthesis of bicyclic pyrrolidines by a rhodium-catalyzed cascade process

scientific article published on 01 December 2004

Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities.

scientific article published on 12 December 2016

Synthesis of 3-amino-3-hydroxymethyloxindoles and 3-hydroxy-3-hydroxymethyloxindoles by Rh2(OAc)4-catalyzed three-component reactions of 3-diazooxindoles with formaldehyde and anilines or water

scientific article published on 16 April 2014

Synthesis of γ-Sulfur-Substituted Ketones via Rh(II)/Sc(III) a Cocatalyzed Three-Component Reaction of Diazo Compounds with Thiophenols and Enones

scientific article published on 22 March 2018

Synthesis, antibacterial activity, and biological evaluation of formyl hydroxyamino derivatives as novel potent peptide deformylase inhibitors against drug-resistant bacteria

scientific article published on 12 August 2014

Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.

scientific article

The rhodium catalyzed three-component reaction of diazoacetates, titanium(IV) alkoxides and aldehydes.

scientific article published on 6 April 2005

Therapeutic melting pot of never in mitosis gene a related kinase 2 (Nek2): a perspective on Nek2 as an oncology target and recent advancements in Nek2 small molecule inhibition

scientific article

Total synthesis of (S)-(+)-imperanene. Effective use of regio- and enantioselective intramolecular carbon-hydrogen insertion reactions catalyzed by chiral dirhodium(II) carboxamidates

scientific article published in May 2002

Trapping of Transient Zwitterionic Intermediates by N-Acylpyridinium Salts: A Palladium-Catalyzed Diastereoselective Three-Component Reaction

scientific article

Trapping of Zwitterionic Intermediates by Isatins and Imines: Synthesis of Benzoxazines Bearing a C4-Quaternary Stereocenter

scientific article published on 13 May 2019

Trapping of oxonium ylide with isatins: efficient and stereoselective construction of adjacent quaternary carbon centers

scientific article published on 11 October 2007

Vinylogous reactivity of enol diazoacetates with donor-acceptor substituted hydrazones. Synthesis of substituted pyrazole derivatives.

scientific article published on 24 January 2013

Zinc-Catalyzed Alkyne-Carbonyl Metathesis of Ynamides with Isatins: Stereoselective Access to Fully Substituted Alkenes

scientific article published on 20 November 2019

List of works by Wenhao Hu

A DFT calculation-inspired Rh(i)-catalyzed reaction via suppression of α-H shift in α-alkyldiazoacetates

A Diastereoselective Multicomponent Reaction for Construction of Alkynylamide-Substituted α,β-Diamino Acid Derivatives To Hunt Hits.

A Rh(II)-catalyzed multicomponent reaction by trapping an α-amino enol intermediate in a traditional two-component reaction pathway.

A Rh(ii)-catalyzed three-component reaction of 3-diazooxindoles with N,N-disubstituted anilines and glyoxylates for the synthesis of 3-aryl-3-substituted oxindoles.

A facile access to polyfunctional oxygen-containing heterocycles via intramolecularly formed protic oxonium ylide trapping processes.

A facile three-component one-pot synthesis of structurally constrained tetrahydrofurans that are t-RNA synthetase inhibitor analogues.

A highly diastereoselective three-component tandem 1,4-conjugated addition-cyclization reaction to multisubstituted pyrrolidines

A highly enantioselective four-component reaction for the efficient construction of chiral β-hydroxy-α-amino acid derivatives

A novel three-component reaction catalyzed by dirhodium(II) acetate: decomposition of phenyldiazoacetate with arylamine and imine for highly diastereoselective synthesis of 1,2-diamines

A strategy to synthesize taxol side chain and (-)-epi cytoxazone via chiral Brønsted acid-Rh(2)(OAc)(4) co-catalyzed enantioselective three-component reactions.

An Isoform-Selective PTP1B Inhibitor Derived from Nitrogen-Atom Augmentation of Radicicol

An enantioselective three-component reaction of diazoacetates with indoles and enals by iridium/iminium co-catalysis.

An ylide transformation of rhodium(I) carbene: enantioselective three-component reaction through trapping of rhodium(I)-associated ammonium ylides by β-nitroacrylates

Asymmetric Counter-Anion-Directed Aminomethylation: Synthesis of Chiral β-Amino Acids via Trapping of an Enol Intermediate

Asymmetric Multicomponent Reactions Based on Trapping of Active Intermediates

Asymmetric Multicomponent Reactions for Efficient Construction of Homopropargyl Amine Carboxylic Esters

Bicyclic pyrazolidinone derivatives from diastereoselective catalytic [3 + 3]-cycloaddition reactions of enoldiazoacetates with azomethine imines.

Bond cleavage, fragment modification and reassembly in enantioselective three-component reactions

Brønsted Acid Catalyzed Enantioselective Assembly of Spirochroman-3,3-oxindoles

Catalyst-Free Halogenation of α-Diazocarbonyl Compounds with N-Halosuccinimides: Synthesis of 3-Halooxindoles or Vinyl Halides.

Catalyst-Free gem-Difunctionalization of Fluoroalkyl-Substituted Diazo Compound with Diselenide or Disulfide and NFSI

Catalytic Asymmetric Four-Component Reaction for the Rapid Construction of 3,3-Disubstituted 3-Indol-3'-yloxindoles

Catalytic asymmetric functionalization of aromatic C-H bonds by electrophilic trapping of metal-carbene-induced zwitterionic intermediates.

Catalytic enantioselective trapping of an alcoholic oxonium ylide with aldehydes: Rh(II)/Zr(IV)-co-catalyzed three-component reactions of aryl diazoacetates, benzyl alcohol, and aldehydes.

Component match in rhodium catalyzed three-component reactions of ethyl diazoacetate, H2O and aryl imines: a highly diastereoselective one-step synthesis of beta-aryl isoserine derivatives.

Cooperative catalysis in highly enantioselective Mannich-type three-component reaction of a diazoacetophenone with an alcohol and an imine

Cooperative catalysis in multicomponent reactions: highly enantioselective synthesis of gamma-hydroxyketones with a quaternary carbon stereocenter

Copper(II)-catalyzed highly diastereoselective three-component reactions of aryl diazoacetates with alcohols and chalcones: an easy access to furan derivatives.

Cu(I)-Catalyzed Three-Component Reaction of Diazo Compound with Terminal Alkyne and Nitrosobenzene for the Synthesis of Trifluoromethyl Dihydroisoxazoles

Cu(I)-Catalyzed Three-Component Reaction of α-Diazo Amide with Terminal Alkyne and Isatin Ketimine via Electrophilic Trapping of Active Alkynoate-Copper Intermediate

DNA binding ligands with in vivo efficacy in murine models of bacterial infection: optimization of internal aromatic amino acids

Deactivating Influence of 3-O-Glycosyl Substituent on Anomeric Reactivity of Thiomannoside Observed in Oligomannoside Synthesis.

Design, synthesis and antibacterial activity of 3-methylenepyrrolidine formyl hydroxyamino derivatives as novel peptide deformylase inhibitors

Design, synthesis, and antibacterial activity of 2,5-dihydropyrrole formyl hydroxyamino derivatives as novel peptide deformylase inhibitors.

Design, synthesis, and structure-activity relationship studies of novel fused heterocycles-linked triazoles with good activity and water solubility.

Diastereoselective three-component reactions of aryldiazoacetates with alcohols/water and alkynals: application to substituted enelactones

Diastereoselectively switchable enantioselective trapping of carbamate ammonium ylides with imines

Diastereoselectivity switch in cooperatively catalyzed three-component reactions of an aryldiazoacetate, an alcohol, and a β,γ-unsaturated α-keto ester

Dirhodium-catalyzed enantioselective C-H insertion of N-(2-benzyloxyethyl)-N-(tert-butyl)diazoacetamide and its application for the synthesis of chiral GABOB.

Discovery of core-structurally novel PTP1B inhibitors with specific selectivity containing oxindole-fused spirotetrahydrofurochroman by one-pot reaction

Divergent Synthesis of Multisubstituted Tetrahydrofurans and Pyrrolidines via Intramolecular Aldol-type Trapping of Onium Ylide Intermediates.

Divergent outcomes of carbene transfer reactions from dirhodium- and copper-based catalysts separately or in combination

Divergent synthesis of chiral heterocycles via sequencing of enantioselective three-component reactions and one-pot subsequent cyclization reactions

Diversity-oriented three-component reactions of diazo compounds with anilines and 4-oxo-enoates

Efficient synthesis of chiral cyclic acetals by metal and Brønsted acid co-catalyzed enantioselective four-component cascade reactions.

Efficient synthesis of oxazoles by dirhodium(II)-catalyzed reactions of styryl diazoacetate with oximes.

Efficient trapping of oxonium ylides with imines: a highly diastereoselective three-component reaction for the synthesis of beta-amino-alpha-hydroxyesters with quaternary stereocenters

Enantioselective Formal [3 + 1 + 1] Cycloaddition Reaction by Ru(II)/Iminium Cocatalysis for Construction of Multisubstituted Pyrrolidines.

Enantioselective Multicomponent Reaction for Rapid Construction of 1,2,5-Triol Derivatives with Vicinal Chiral Centers.

Enantioselective Synthesis of α-Mercapto-β-amino Esters via Rh(II)/Chiral Phosphoric Acid-Cocatalyzed Three-Component Reaction of Diazo Compounds, Thiols, and Imines.

Enantioselective Trapping of Oxonium Ylides by 3-Hydroxyisoindolinones via a Formal SN1 Pathway for Construction of Contiguous Quaternary Stereocenters.

Enantioselective oxidative functionalization of the Csp3-H bond adjacent to a nitrogen atom for rapid access to β-hydroxyl-α-amino acid derivatives

Enantioselective palladium(II) phosphate catalyzed three-component reactions of pyrrole, diazoesters, and imines

Enantioselective trapping of phosphoramidate ammonium ylides with imino esters for synthesis of 2,3-diaminosuccinic acid derivatives.

Facile synthesis of 3-aryloxindoles via brønsted acid catalyzed Friedel-Crafts alkylation of electron-rich arenes with 3-diazooxindoles.

Gold(I)-Catalyzed and H2O-Mediated Carbene Cascade Reaction of Propargyl Diazoacetates: Furan Synthesis and Mechanistic Insights

Gold-Catalyzed 1,2-Acyloxy Migration/Coupling Cascade of Propargyl Diazoacetates: Synthesis of Isomycin Derivatives

Gold-Catalyzed Oxidative Cyclization/Aldol Addition of Homopropargyl Alcohols with Isatins

Green chemistry approaches to the regioselective synthesis of spiro heterobicyclic rings using iodine as a new and efficient catalyst under solvent-free conditions

Highly Enantioselective Three-Component Reactions of tert-Butyl Diazoacetate with Arylamines and Imines: An Efficient Synthesis of α,β-Bis(arylamino) Acid Derivatives

Highly chemoselective 2,4,5-triaryl-1,3-dioxolane formation from intermolecular 1,3-dipolar addition of carbonyl ylide with aryl aldehydes

Highly diastereoselective multicomponent cascade reactions: efficient synthesis of functionalized 1-indanols

Highly diastereoselective synthesis of 3-hydroxy-2,2,3-trisubstituted indolines via intramolecular trapping of ammonium ylides with ketones

Highly diastereoselective synthesis of fully substituted tetrahydrofurans by a one-pot cascade reaction of aryldiazoacetates with allyl alcohols.

Highly efficient synthesis of mixed 3,3'-bisindoles via Rh(II)-catalyzed three-component reaction of 3-diazooxindoles with indoles and ethyl glyoxylate

Highly enantioselective catalytic synthesis of functionalized chiral diazoacetoacetates

Highly enantioselective trapping of zwitterionic intermediates by imines

In search of high stereocontrol for the construction of cis-disubstituted cyclopropane compounds. Total synthesis of a cyclopropane-configured urea-PETT analogue that is a HIV-1 reverse transcriptase inhibitor

Iron catalyzed efficient synthesis of poly-functional primary amines via the direct use of ammonia.

Iron porphyrin-catalyzed three-component reaction of ethyl diazoacetate with aliphatic amines and β,γ-unsaturated α-keto esters.

Novel C-C bond formation through addition of ammonium ylides to arylaldehydes: a facile approach to beta-aryl-beta-hydroxy alpha-amino acid frameworks

Novel multicomponent reactions via trapping of protic onium ylides with electrophiles

Optimization of P2Y12 Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties

Pd(II)-catalyzed formal [4+1] cycloaddition reactions of diazoacetates and aryl propargyl alcohols to form 2,5-dihydrofurans

Pd(II)/β-ICD-Cocatalyzed Asymmetric Route to Oxindole Scaffold via Cascade Reaction of Diazoacetamides and MBH-Carbonates.

Privilege-Structure-Oriented Three-Component Asymmetric Aminomethylation: Assembly of Chiral 3-Aminomethyl Indolones

Protein Arginine Methyltransferase 5 (PRMT5) as an Anticancer Target and Its Inhibitor Discovery

Regio- and Diastereoselective Three-Component Reactions via Trapping of Ammonium Ylides with N-Alkylquinolinium Salts: Synthesis of Multisubstituted Tetra- and Dihydroquinoline Derivatives.

Regio- and diastereoselective construction of α-hydroxy-δ-amino ester derivatives via 1,4-conjugate addition of β,γ-unsaturated N-sulfonylimines.