List of works - Wataru Nomura

A CD4 mimic as an HIV entry inhibitor: pharmacokinetics.

scientific article published on 17 October 2013

A cell cycle-dependent CRISPR-Cas9 activation system based on an anti-CRISPR protein shows improved genome editing accuracy

scientific article published on 23 October 2020

A future perspective on the development of chemokine receptor CXCR4 antagonists.

scientific article published on October 2008

A synthetic C34 trimer of HIV-1 gp41 shows significant increase in inhibition potency.

scientific article published on 13 January 2012

Anti-HIV screening for cell-penetrating peptides using chloroquine and identification of anti-HIV peptides derived from matrix proteins.

scientific article

Anti-HIV-1 peptide derivatives based on the HIV-1 Co-receptor CXCR4.

scientific article published on 23 August 2013

Azamacrocyclic metal complexes as CXCR4 antagonists

scientific article published on 10 February 2011

Bivalent ligands of CXCR4 with rigid linkers for elucidation of the dimerization state in cells

scientific article published on 25 October 2010

CD4 mimics as HIV entry inhibitors: lead optimization studies of the aromatic substituents.

scientific article published on 7 March 2013

CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist.

scientific article published on 3 August 2010

CXCR4-derived synthetic peptides inducing anti-HIV-1 antibodies.

scientific article published on 21 September 2013

Conjugation of cell-penetrating peptides leads to identification of anti-HIV peptides from matrix proteins.

scientific article

Design, synthesis and biological evaluation of low molecular weight CXCR4 ligands

scientific article published on 06 February 2019

Development of a NanoBRET-Based Sensitive Screening Method for CXCR4 Ligands

scientific article published on 11 April 2019

Development of a traceable linker containing a thiol-responsive amino acid for the enrichment and selective labelling of target proteins

scientific article published on 01 June 2014

Effects of DNA binding of the zinc finger and linkers for domain fusion on the catalytic activity of sequence-specific chimeric recombinases determined by a facile fluorescent system

scientific article published on 8 February 2012

Effects of length and position of an extended linker on sequence-selective DNA recognition of zinc finger peptides.

scientific article published in December 2003

Effects of linking 15-zinc finger domains on DNA binding specificity and multiple DNA binding modes.

scientific article

Efficient and orthogonal transcription regulation by chemically inducible artificial transcription factors

scientific article published on 02 November 2018

Evaluation of a synthetic C34 trimer of HIV-1 gp41 as AIDS vaccines.

scientific article

Exploration of labeling by near infrared dyes of the polyproline linker for bivalent-type CXCR4 ligands

scientific article published on 28 September 2015

Fluorescence-quenching screening of protein kinase C ligands with an environmentally sensitive fluorophore.

scientific article

Fluorescent-responsive synthetic C1b domains of protein kinase Cδ as reporters of specific high-affinity ligand binding

scientific article

Fluorogenically active leucine zipper peptides as tag-probe pairs for protein imaging in living cells

scientific article published in January 2009

Fluorophore labeling enables imaging and evaluation of specific CXCR4-ligand interaction at the cell membrane for fluorescence-based screening

scientific article

In vivo site-specific DNA methylation with a designed sequence-enabled DNA methylase.

scientific article published on 21 June 2007

Influence of TFIIIA-type linker at the N- or C-terminal of nine-zinc finger protein on DNA-binding site

scientific article published on 01 January 2003

Intense blue fluorescence in a leucine zipper assembly

scientific article published on 8 February 2011

Low-molecular-weight CXCR4 ligands with variable spacers.

scientific article

Microwave-Assisted Synthesis of Azacoumarin Fluorophores and the Fluorescence Characterization

scientific article published on 2 February 2017

Multiconnection of identical zinc finger: implication for DNA binding affinity and unit modulation of the three zinc finger domain

scientific article published on 01 March 2001

Peptide HIV-1 integrase inhibitors from HIV-1 gene products.

scientific article

Peptidic HIV integrase inhibitors derived from HIV gene products: structure-activity relationship studies.

scientific article

Pharmacophore-based small molecule CXCR4 ligands.

scientific article

Remodeling of dynamic structures of HIV-1 envelope proteins leads to synthetic antigen molecules inducing neutralizing antibodies.

scientific article published on April 2010

Significant effect of linker sequence on DNA recognition by multi-zinc finger protein

scientific article published on 01 April 2001

Structure-activity relationship study of CXCR4 antagonists bearing the cyclic pentapeptide scaffold: identification of the new pharmacophore

scientific article

Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids

scientific article published on 20 July 2009

Synthesis of hydrophilic caged DAG-lactones for chemical biology applications

scientific article published on 20 May 2020

Synthesis of protein kinase Cdelta C1b domain by native chemical ligation methodology and characterization of its folding and ligand binding.

scientific article

Synthetic caged DAG-lactones for photochemically controlled activation of protein kinase C.

scientific article

TALEN-Based Chemically Inducible, Dimerization-Dependent, Sequence-Specific Nucleases

scientific article published on 21 October 2019

Trivalent ligands for CXCR4 bearing polyproline linkers show specific recognition for cells with increased CXCR4 expression

scientific article published on 17 July 2015

Utilization of the Heavy Atom Effect for the Development of a Photosensitive 8-Azacoumarin-Type Photolabile Protecting Group.

scientific article published on 15 October 2015

List of works by Wataru Nomura

A CD4 mimic as an HIV entry inhibitor: pharmacokinetics.

A cell cycle-dependent CRISPR-Cas9 activation system based on an anti-CRISPR protein shows improved genome editing accuracy

A future perspective on the development of chemokine receptor CXCR4 antagonists.

A synthetic C34 trimer of HIV-1 gp41 shows significant increase in inhibition potency.

Anti-HIV screening for cell-penetrating peptides using chloroquine and identification of anti-HIV peptides derived from matrix proteins.

Anti-HIV-1 peptide derivatives based on the HIV-1 Co-receptor CXCR4.

Azamacrocyclic metal complexes as CXCR4 antagonists

Bivalent ligands of CXCR4 with rigid linkers for elucidation of the dimerization state in cells

CD4 mimics as HIV entry inhibitors: lead optimization studies of the aromatic substituents.

CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist.

CXCR4-derived synthetic peptides inducing anti-HIV-1 antibodies.

Conjugation of cell-penetrating peptides leads to identification of anti-HIV peptides from matrix proteins.

Design, synthesis and biological evaluation of low molecular weight CXCR4 ligands

Development of a NanoBRET-Based Sensitive Screening Method for CXCR4 Ligands

Development of a traceable linker containing a thiol-responsive amino acid for the enrichment and selective labelling of target proteins

Effects of DNA binding of the zinc finger and linkers for domain fusion on the catalytic activity of sequence-specific chimeric recombinases determined by a facile fluorescent system

Effects of length and position of an extended linker on sequence-selective DNA recognition of zinc finger peptides.

Effects of linking 15-zinc finger domains on DNA binding specificity and multiple DNA binding modes.

Efficient and orthogonal transcription regulation by chemically inducible artificial transcription factors

Evaluation of a synthetic C34 trimer of HIV-1 gp41 as AIDS vaccines.

Exploration of labeling by near infrared dyes of the polyproline linker for bivalent-type CXCR4 ligands

Fluorescence-quenching screening of protein kinase C ligands with an environmentally sensitive fluorophore.

Fluorescent-responsive synthetic C1b domains of protein kinase Cδ as reporters of specific high-affinity ligand binding

Fluorogenically active leucine zipper peptides as tag-probe pairs for protein imaging in living cells

Fluorophore labeling enables imaging and evaluation of specific CXCR4-ligand interaction at the cell membrane for fluorescence-based screening

In vivo site-specific DNA methylation with a designed sequence-enabled DNA methylase.

Influence of TFIIIA-type linker at the N- or C-terminal of nine-zinc finger protein on DNA-binding site

Intense blue fluorescence in a leucine zipper assembly

Low-molecular-weight CXCR4 ligands with variable spacers.

Microwave-Assisted Synthesis of Azacoumarin Fluorophores and the Fluorescence Characterization

Multiconnection of identical zinc finger: implication for DNA binding affinity and unit modulation of the three zinc finger domain

Peptide HIV-1 integrase inhibitors from HIV-1 gene products.

Peptidic HIV integrase inhibitors derived from HIV gene products: structure-activity relationship studies.

Pharmacophore-based small molecule CXCR4 ligands.

Remodeling of dynamic structures of HIV-1 envelope proteins leads to synthetic antigen molecules inducing neutralizing antibodies.

Significant effect of linker sequence on DNA recognition by multi-zinc finger protein

Structure-activity relationship study of CXCR4 antagonists bearing the cyclic pentapeptide scaffold: identification of the new pharmacophore

Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids

Synthesis of hydrophilic caged DAG-lactones for chemical biology applications

Synthesis of protein kinase Cdelta C1b domain by native chemical ligation methodology and characterization of its folding and ligand binding.

Synthetic caged DAG-lactones for photochemically controlled activation of protein kinase C.

TALEN-Based Chemically Inducible, Dimerization-Dependent, Sequence-Specific Nucleases

Trivalent ligands for CXCR4 bearing polyproline linkers show specific recognition for cells with increased CXCR4 expression

Utilization of the Heavy Atom Effect for the Development of a Photosensitive 8-Azacoumarin-Type Photolabile Protecting Group.