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List of works by Brad S. Rothberg

A slick, slack pathway through the pore

scientific article published on 05 March 2017

Allosteric mechanism of Ca2+ activation and H+-inhibited gating of the MthK K+ channel

scientific article

Allosteric modulation of ion channels: the case of maxi-K.

scientific article published on 30 March 2004

An old probe sheds new light on BK channel pore structure.

scientific article published on 10 November 2014

Analysis of Ca(2+)-binding sites in the MthK RCK domain by X-ray crystallography

scientific article

Bimane fluorescence scanning suggests secondary structure near the S3-S4 linker of BK channels

scientific article published on 25 February 2009

Blocker state dependence and trapping in hyperpolarization-activated cation channels: evidence for an intracellular activation gate

scientific article

Charge of the Proton Channel

scientific article published on 01 June 2018

Chronic ethanol treatment differentially affects muscarinic receptor responses in rat hippocampus

scientific article published in November 1991

Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site

scientific article

Gating kinetics of single large-conductance Ca2+-activated K+ channels in high Ca2+ suggest a two-tiered allosteric gating mechanism

scientific article

Genetic screening for functionality of bacterial potassium channel mutants using K+ uptake-deficient Escherichia coli

scientific article published in January 2006

Initial steps of inactivation at the K+ channel selectivity filter

scientific article

Investigating single-channel gating mechanisms through analysis of two-dimensional dwell-time distributions

scientific article published on 01 January 1998

Isotope labeling strategies for analysis of an ion channel cytoplasmic domain by NMR spectroscopy

scientific article published in January 2013

Kinetic structure of large-conductance Ca2+-activated K+ channels suggests that the gating includes transitions through intermediate or secondary states. A mechanism for flickers.

scientific article

Long-term effects of chronic ethanol on muscarinic receptor binding in rat brain

scientific article published in December 1996

MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival

scientific article

Mechanism of beta4 subunit modulation of BK channels.

scientific article

Mechanism of increased BK channel activation from a channel mutation that causes epilepsy.

scientific article published on 09 February 2009

Modulation of MthK potassium channel activity at the intracellular entrance to the pore.

scientific article published on 25 May 2006

Molecular architecture and divalent cation activation of TvoK, a prokaryotic potassium channel

scientific article

Molecular determinants of Ca2+ sensitivity at the intersubunit interface of the BK channel gating ring

scientific article published on 11 January 2018

Molecular mechanism of BK channel activation by the smooth muscle relaxant NS11021

scientific article published on 01 June 2020

Molecular mechanism of a potassium channel gating through activation gate-selectivity filter coupling

scientific article published on 26 November 2019

Movements near the gate of a hyperpolarization-activated cation channel

scientific article

Neuronal STIMulation at rest

scientific article

Permeating disciplines: Overcoming barriers between molecular simulations and classical structure-function approaches in biological ion transport.

scientific article published on 16 December 2017

Return of the electric binding site

scientific article published in November 2008

STIM1 dimers undergo unimolecular coupling to activate Orai1 channels

scientific article published on 24 September 2015

Structure and function of multiple Ca2+-binding sites in a K+ channel regulator of K+ conductance (RCK) domain

scientific article

The BK channel: a vital link between cellular calcium and electrical signaling.

scientific article published on 21 September 2012

The STIM1-binding site nexus remotely controls Orai1 channel gating.

scientific article published on 8 December 2016

Understanding the conformational motions of RCK gating rings

scientific article published on 28 February 2017

Voltage and Ca2+ activation of single large-conductance Ca2+-activated K+ channels described by a two-tiered allosteric gating mechanism.

scientific article published in July 2000

Voltage-dependent inactivation gating at the selectivity filter of the MthK K+ channel

scientific article

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