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List of works by Christian Funck-Brentano

2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

scientific article

2010 Focused Update of ESC Guidelines on device therapy in heart failure

article published November 2010 in European Journal of Heart Failure

2010 Focused Update of ESC Guidelines on device therapy in heart failure

article published 1 November 2010 in EP Europace

2010 Focused Update of ESC Guidelines on device therapy in heart failure: An update of the 2008 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure and the 2007 ESC guidelines for cardiac and resynchronization therapy De

article published 27 August 2010 in European Heart Journal

2012 focused update of the ESC Guidelines for the management of atrial fibrillation ⬇️

scientific article published on August 24, 2012

2013 ESC guidelines on the management of stable coronary artery disease

scientific article published on 30 August 2013

2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

scientific article

2014 ESC/ESA Guidelines on non-cardiac surgery

article

2014 ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and management: The Joint Task Force on non-cardiac surgery: cardiovascular assessment and management of the European Society of Cardiology (ESC) and the European Society of A

scientific article

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS):

scientific article published on 29 August 2015

3-Hydroxybenzo[a]pyrene in the urine of smokers and non-smokers

scientific article published on 6 January 2006

A study of the relative bioavailability of cysteamine hydrochloride, cysteamine bitartrate and phosphocysteamine in healthy adult male volunteers

scientific article published on January 1999

About fundamentals and sermonizers. Author's response to the letter on the article “The BIAL/Biotrial case of death of a human volunteer in the first-in-human study of BIA 10-2474: Are we missing the fundamentals?”

Actualización detallada de las guías de la ESC para el manejo de la fibrilación auricular de 2012

Acute coronary syndrome in human immunodeficiency virus-infected patients: characteristics and 1 year prognosis

scientific article published on 21 October 2010

Amiodarone Interacts with Simvastatin but not with Pravastatin Disposition Kinetics

Amiodarone concentrations in plasma and fat tissue during chronic treatment and related toxicity

scientific article published on 02 February 2009

Anti-ischaemic medication must be adapted to each patient's characteristics and preferences in patients with chronic coronary syndromes

scientific article published on 01 January 2020

Anticancer drug-induced cardiac rhythm disorders: Current knowledge and basic underlying mechanisms.

scientific article published on 23 April 2018

Are intracardiac electrophysiological studies in healthy volunteers ethical? Time for multinational recommendations

scientific article

Assessment of CYP2D6 activity in very elderly healthy subjects

scientific article published on 01 January 1996

Assessment of CYP2D6 and CYP2C19 activity in vivo in humans: A cocktail study with dextromethorphan and chloroguanide alone and in combination

scientific article published on 01 December 1999

Assessment of individual CYP2D6 activity in extensive metabolizers with renal failure: comparison of sparteine and dextromethorphan.

scientific article published in May 1996

Assessment of the effect of a single oral dose of telithromycin on sotalol-induced qt interval prolongation in healthy women

scientific article published in August 2005

Association of Oral Contraceptives With Drug-Induced QT Interval Prolongation in Healthy Nonmenopausal Women

scientific article published on 01 September 2018

Beta-blockade in CHF: from contraindication to indication

Bisoprolol dose-response relationship in patients with congestive heart failure: a subgroup analysis in the cardiac insufficiency bisoprolol study(CIBIS II).

scientific article published in March 2003

CYP2D6- and CYP3A-dependent metabolism of dextromethorphan in humans

Can we override clopidogrel resistance?

scientific article published in June 2009

Cardiac arrhythmia considerations of hormone cancer therapies

scientific article published on 01 April 2019

Cardiovascular safety of salmeterol in COPD.

scientific article

Clinical pharmacology of anti-angiogenic drugs in oncology

scientific article

Combined glutathione-S-transferase M1 and T1 genetic polymorphism and tacrine hepatotoxicity.

scientific article published in April 2000

Comment garantir des données médicales de qualité dans les études cliniques, pharmaco-épidémiologiques et en pharmacovigilance ?

Comment on "Clinical trials update from the European Society of Cardiology meeting 2005: CIBIS-III, by JGF Cleland and others".

scientific article published in March 2006

Comparison of sympathetic modulation induced by single oral doses of mibefradil, amlodipine, and nifedipine in healthy volunteers.

scientific article

Comparison of tolerance to intravenous nitroglycerin during nicorandil and intermittent nitroglycerin patch in healthy volunteers

scientific article

Complex Association of Sex Hormones on Left Ventricular Systolic Function: Insight into Sexual Dimorphism

scientific article published on 12 December 2017

Complex Influence of Gonadotropins and Sex Steroid Hormones on QT Interval Duration

scientific article published on 11 May 2016

Comprehensive efforts to increase adherence to statin therapy

scientific article published on 10 January 2017

Conflicts of interests in the area of healthcare products and technology. Current state of affairs and recommendations

scientific article published in July 2012

Corrected QT interval in anti-SSA-positive adults with connective tissue disease: Comment on the article by Lazzerini et al

scholarly article by Nathalie Costedoat-Chalumeau et al published 2005 in Arthritis and Rheumatism

Corrigendum to: 'Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery: The Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Non-cardiac Surgery of

scholarly article published in European Heart Journal

Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study

scientific article

Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity.

scientific article

Deep learning analysis of electrocardiogram for risk prediction of drug-induced arrhythmias and diagnosis of long QT syndrome

scientific article

Development and Validation of a Fast Ultra-High Performance Liquid Chromatography-Fluorescent Method for the Quantification of Hydroxychloroquine and Its Metabolites in Patients With Lupus

scientific article published on 01 August 2019

Development and validation of a rapid and simple LC-MS/MS method for quantification of vemurafenib in human plasma: application to a human pharmacokinetic study

scientific article

Digoxin pharmacokinetics and MDR1 genetic polymorphisms

Dipyridamole enhances digoxin bioavailability via P-glycoprotein inhibition

scientific article

Droperidol and ondansetron in vitro electrophysiological drug interaction study

scientific article published on 12 August 2009

Droperidol and ondansetron-induced QT interval prolongation: a clinical drug interaction study

scientific article published in August 2008

Droperidol-induced proarrhythmia: the beginning of an answer?

scientific article published in October 2007

Drug interactions and hepatitis produced by some macrolide antibiotics

scientific article published on 01 July 1985

Drug-induced aseptic meningitis: 329 cases from the French pharmacovigilance database analysis

scientific article published on 01 August 2019

Dynamic analysis of dofetilide-induced changes in ventricular repolarization

scientific article published on September 1998

ERRATUM

scholarly article published in Fundamental and Clinical Pharmacology

ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC)

scientific article

ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: the Task Force on diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and developed in collab

scientific article

ESC Guidelines on the diagnosis and treatment of peripheral artery diseases: Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries * The Task Force on the Diagnosis and

article published in 2011

ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the

scientific article

Effect of Contrasted Sodium Diets on the Pharmacokinetics and Pharmacodynamic Effects of Renin–Angiotensin System Blockers

Effect of a single oral dose of moxifloxacin (400 mg and 800 mg) on ventricular repolarization in healthy subjects

scientific article published on 01 December 2000

Effect of an increased clopidogrel maintenance dose or lansoprazole co-administration on the antiplatelet response to clopidogrel in CYP2C19-genotyped healthy subjects

scientific article published on 21 December 2009

Effect of interferon alpha-ribavirin bitherapy on cytochrome P450 1A2 and 2D6 and N-acetyltransferase-2 activities in patients with chronic active hepatitis C.

scientific article published in June 2002

Effect of oral administration of a new calcium channel blocking agent, bepridil on antipyrine clearance in man.

scientific article

Effect of single and repeated oral doses of telithromycin on cardiac QT interval in healthy subjects

scientific article published in March 2003

Effect on mode of death of heart failure treatment started with bisoprolol followed by Enalapril, compared to the opposite order: results of the randomized CIBIS III trial

scientific article published in April 2011

Effectiveness of heart rate control on hemodynamics in critically ill patients with atrial tachyarrhythmias managed by amiodarone

scholarly article by Joe-Elie Salem et al published August 2017 in Pharmacological Research

Effects of Dihydroartemisinin-Piperaquine Phosphate and Artemether-Lumefantrine on QTc Interval Prolongation

scientific article published in Scientific Reports

Effects of HIV Protease Inhibitors on Cardiac Conduction Velocity in Unselected HIV-Infected Patients

article

Effects of a single oral dose of sparfloxacin on ventricular repolarization in healthy volunteers

scientific article published on June 1996

Effects of cigarette smoking on short-term variability of blood pressure in smoking and non smoking healthy volunteers

scientific article published on 01 January 1999

Effects of erythromycin on hepatic drug-metabolizing enzymes in humans

scientific article published on 01 March 1983

Effects of oxytocin on Purkinje fibres

Effects of rabeprazole on the antiplatelet effects and pharmacokinetics of clopidogrel in healthy volunteers

scientific article published on 15 November 2013

Effects of tedisamil, atenolol and their combination on heart and rate-dependent QT interval in healthy volunteers

scientific article published on October 1997

Effects of testosterone on ventricular repolarization in hypogonadic men.

scientific article

Effects of type of smoking (pipe, cigars or cigarettes) on biological indices of tobacco exposure and toxicity

article

European guidelines on cardiovascular disease prevention in clinical practice: executive summary. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice ...

scientific article published in September 2007

European guidelines on cardiovascular disease prevention in clinical practice: full text. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by rep

scientific article published in September 2007

Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method

scientific article published in Scientific Reports

Fast, accurate and easy-to-teach QT interval assessment: The triplicate concatenation method

scientific article published on 11 May 2017

Frequency of cytochrome P450 2C9 allelic variants in the Chinese and French populations

article

GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, "GENEREPOL study": Lack of common variants with large effect sizes.

scientific article published on 11 August 2017

Genetic and environmental risk factors for oral anticoagulant overdose

scientific article published on 18 February 2003

Genetically determined stereoselective excretion of encainide in humans and electrophysiologic effects of its enantiomers in canine cardiac Purkinje fibers

scientific article published on 01 May 1991

Genetically-determined interaction between propafenone and low dose quinidine: role of active metabolites in modulating net drug effect

scientific article

Glutathione S-transferase theta genetic polymorphism might influence tacrine hepatotoxicity in Alzheimer's patients

scientific article published in June 1997

Grupo de Trabajo Conjunto sobre cirugía no cardiaca: Evaluación y manejo cardiovascular de la Sociedad Europea de Cardiología (ESC) y la European Society of Anesthesiology (ESA)

Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery: the Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Non-cardiac Surgery of the European Soc

scientific article

Guía ESC/ERS 2015 sobre diagnóstico y tratamiento de la hipertensión pulmonar

article

Guía de Práctica Clínica de la ESC 2013 sobre diagnóstico y tratamiento de la cardiopatía isquémica estable

scientific article published in February 2014

Guía de práctica clínica de la ESC para el manejo del infarto agudo de miocardio en pacientes con elevación del segmento ST

Guía de práctica clínica de la ESC sobre diabetes, prediabetes y enfermedad cardiovascular, en colaboración con la European Association for the Study of Diabetes

article

Guía de práctica clínica de la ESC sobre diagnóstico y tratamiento de la insuficiencia cardiaca aguda y crónica 2012

Guía de práctica clínica para el diagnóstico y manejo del síncope (versión 2009)

Guías de práctica clínica para el tratamiento de la hipertensión arterial 2007

article

Heart conduction disorders related to antimalarials toxicity: an analysis of electrocardiograms in 85 patients treated with hydroxychloroquine for connective tissue diseases

scientific article published on 3 January 2007

How can the quality of medical data in pharmacovigilance, pharmacoepidemiology and clinical studies be guaranteed?

scientific article

Human plasma quantification of droperidol and ondansetron used in preventing postoperative nausea and vomiting with a LC/ESI/MS/MS method

scientific article published on 16 December 2010

Hypogonadism as a Reversible Cause of Torsades de Pointes in Men

scientific article published on 01 July 2018

Impact of negative inotropic drugs on accuracy of diastolic stress echocardiography for evaluation of left ventricular filling pressure

scientific article published on 25 August 2017

Improved high-performance liquid chromatographic assay for encainide and its metabolites in human body fluids

scientific article published on 01 May 1989

In Memoriam: Jean-Louis Funck-Brentano 1924-1997

In vitro cardiovascular effects of dihydroartemisin-piperaquine combination compared with other antimalarials

scientific article

Increased long QT and torsade de pointes reporting on tamoxifen compared with aromatase inhibitors

scientific article published on 02 May 2018

Influence of amiodarone on genetically determined drug metabolism in humans

article

Influence of endogenous oestrogens on QT interval duration

scientific article published in September 2003

Influence of food on the pharmacokinetics of perindopril and the time course of angiotensin-converting enzyme inhibition in serum.

scientific article published in March 1990

Influence of liver cirrhosis on sertraline pharmacokinetics.

scientific article

Influence of order and type of drug (bisoprolol vs. enalapril) on outcome and adverse events in patients with chronic heart failure: a post hoc analysis of the CIBIS-III trial

scientific article published on 6 May 2011

Influence of steroid hormones on ventricular repolarization

scientific article published on 21 July 2016

Influence of the CYP1A2 inhibitor fluvoxamine on tacrine pharmacokinetics in humans* ⬇️

scientific article published on June 1, 1997

Interindividual variability in dabigatran and rivaroxaban exposure: contribution ofABCB1genetic polymorphisms and interaction with clarithromycin

scientific article published on 06 February 2017

Intravenous Clopidogrel (MDCO-157) Compared with Oral Clopidogrel: The Randomized Cross-Over AMPHORE Study

scientific article published on 19 September 2015

Is diclofenac a valuable CYP2C9 probe in humans?

scientific article published in January 2001

Les conflits d’intérêts dans le domaine des produits et de technologies de santé : état des lieux et recommandations

scientific article published on 01 July 2012

Lymphocyte P-glycoprotein expression and activity before and after rifampicin in man

scientific article published on 01 September 2000

Major pitfalls of protein kinase inhibitors prescription: A review of their clinical pharmacology for daily use

scientific article published on 16 June 2019

Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology:

scientific article

Measurement of CYP2D6 and CYP3A4 activity in vivo with dextromethorphan: sources of variability and predictors of adverse effects in 419 healthy subjects

scientific article published on 17 November 2005

Mibefradil, a potent CYP3A inhibitor, does not alter pravastatin pharmacokinetics

scientific article published on 01 January 1999

Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients with Atrial Tachyarrhythmias

scientific article published on 5 March 2016

Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells

scientific article published on 30 January 2017

Mycophenolic acid area under the curve correlates with disease activity in lupus patients treated with mycophenolate mofetil

scientific article published in July 2010

Open letter on access to the BIA 10-2474 clinical trial data

scientific article published on 7 December 2016

P-glycoprotein influences urinary excretion of aldosterone in healthy individuals

scientific article published on 01 November 2019

Pharmacogenetics of acenocoumarol pharmacodynamics.

scientific article published in May 2004

Pharmacokinetic and pharmacodynamic drug interactions between digoxin and macrogol 4000, a laxative polymer, in healthy volunteers

scientific article

Pharmacokinetic and pharmacodynamic interaction between grapefruit juice and halofantrine

scientific article

Pharmacokinetic and pharmacodynamic interaction of N-acetyl procainamide and procainamide in humans

scientific article (publication date: September 1989)

Pharmacokinetic and pharmacodynamic modeling of the effects of oral and intravenous administrations of dofetilide on ventricular repolarization*

article

Pharmacokinetic and pharmacodynamic profiles of d-sotalol and d,l-sotalol.

scientific article published on November 1993

Pharmacokinetic-pharmacodynamic modeling of the effects of ivabradine, a direct sinus node inhibitor, on heart rate in healthy volunteers.

scientific article

Pharmacokinetics and electrocardiographic effects of a new controlled-release form of flecainide acetate: comparison with the standard form and influence of the CYP2D6 polymorphism

scientific article published in August 2002

Pharmacokinetics and platelet antiaggregating effects of beraprost, an oral stable prostacyclin analogue, in healthy volunteers

scientific article published on November 1993

Pharmacology and mechanisms of action of new oral anticoagulants.

scientific article published on 25 September 2014

Plasma vemurafenib concentrations in advanced BRAFV600mut melanoma patients: impact on tumour response and tolerance

scientific article published on 21 April 2015

Poorex vivoinduction of T-cell responses to idiotype or tumor cell lysate-pulsed autologous dendritic cells in advanced pre-treated multiple myeloma

article

Postoperative analgesia and recovery course after major colorectal surgery in elderly patients: a randomized comparison between intrathecal morphine and intravenous PCA morphine

scientific article published on November 2006

Prediction of sotalol-induced maximum steady-state QTc prolongation from single-dose administration in healthy volunteers

scientific article published on 01 October 1992

Predictors of medical events and of their competitive interactions in the Cardiac Insufficiency Bisoprolol Study 2 (CIBIS-2) ⬇️

scientific article published on December 1, 2001

Predictors of medical events in patients enrolled in the Cardiac Insufficiency Bisoprolol Study (CIBIS): A study of the interactions between [beta ]-blocker therapy and occurrence of critical events using analysis of competitive risks

scientific article published on 01 February 2000

Prevention of Invasive Aspergillus Fungal Infections with the Suspension and Delayed-Release Tablet Formulations of Posaconazole in Patients with Haematologic Malignancies

scientific article

Prolongation of QTc interval after postoperative nausea and vomiting treatment by droperidol or ondansetron

scientific article published in June 2005

Prolonged Ventricular Repolarization in Hypertension: Is It Heart Rate?

Prospective pharmacokinetically based development of effective infusion regimens for ACC–9358, a new antiarrhythmic drug

article

Protective effect of 16,16-dimethyl prostaglandin E2 on the hepatotoxicity of bromobenzene in mice.

scientific article published on January 1984

QT interval measurement: evaluation of automatic QTc measurement and new simple method to calculate and interpret corrected QT interval

scientific article published in February 2006

QT interval prolongation after oxytocin bolus during surgical induced abortion

scientific article published in October 2004

Randomized study of the effect of gadopiclenol, a new gadolinium-based contrast agent, on the QTc interval in healthy subjects

scientific article published on 17 April 2020

Rapid Development of Nitrate Tolerance in Healthy Volunteers

article

Rate dependence of ventricular extrasystoles: computer identification and quantitative analysis

scientific article published on 01 February 1988

Rate-corrected QT interval: techniques and limitations

scientific article

Rate-dependence of class III actions in the heart.

scientific article

Recainam dose titration and pharmacokinetics in patients with resistant arrhythmias

scientific article

Regulation of renal cytochrome P-450

scientific article published on 01 February 1985

Relation between baseline LDL-cholesterol and cardiovascular outcomes in high cardiovascular risk hypertensive patients: A post-hoc SPRINT data analysis

scientific article published on 15 January 2019

Relation between chloroguanide bioactivation to cycloguanil and the genetically determined metabolism of mephenytoin in humans

scientific article published on 01 May 1992

Relationship between HIV protease inhibitors and QTc interval duration in HIV-infected patients: a cross-sectional study

scientific article

Relationships between acute and chronic beta-blocking effects of bisoprolol in healthy volunteers: a practical approach to predict intensity of beta-blockade

scientific article published in April 1994

Renal and vascular effects of S21402, a dual inhibitor of angiotensin-converting enzyme and neutral endopeptidase, in healthy subjects with hypovolemia

scientific article published in June 2002

Reply to the letter to the editor 'Plasma vemurafenib concentrations in advanced BRAFV600mut melanoma patients: impact on tumor response and tolerance' by Funck-Brentano et al.

scientific article

Reproducibility of non-invasive measurement and of short-term variability of blood pressure and heart rate in healthy volunteers.

scientific article

Rivaroxaban pharmacodynamics in healthy volunteers evaluated with thrombin generation and the active protein C system: Modeling and assessing interindividual variability

scientific article published on 09 July 2019

Safety and pharmacokinetics of the CIME combination of drugs and their metabolites after a single oral dosing in healthy volunteers.

scientific article published on 3 December 2014

Serum concentration and vascular expression of adiponectin are differentially associated with the diabetic calcifying peripheral arteriopathy

scientific article published on 29 April 2019

Simultaneous determination of rivaroxaban and dabigatran levels in human plasma by high-performance liquid chromatography–tandem mass spectrometry

scientific article published on 15 August 2014

Sirolimus and mTOR Inhibitors: A Review of Side Effects and Specific Management in Solid Organ Transplantation

scientific article published on 01 July 2019

Statin therapy and low-density lipoprotein cholesterol reduction in HIV-infected individuals after acute coronary syndrome: Results from the PACS-HIV lipids substudy

scientific article

Steady-State versus Non-Steady-State QT-RR Relationships in 24-hour Holter Recordings

scientific article published on 01 March 2000

The BIAL/Biotrial case of death of a human volunteer in the first-in-human study of BIA 10-2474: Are we missing the fundamentals?

article published in 2016

The pharmacokinetics of perindopril in patients with liver cirrhosis

scientific article

Therapeutic drug monitoring of clozapine in a hemodialysed smoking patient with schizophrenia

scientific article

Tolérance cardiaque de la moxifloxacine: expérience clinique issue d'une large étude observationnelle française en pratique médicale usuelle (étude IMMEDIAT)

article

Topics in Clinical Pharmacology: Encainide: A Useful New Antiarrhythmic Drug

scientific article published on 01 July 1988

Topics in clinical pharmacology: buspirone: a new nonbenzodiazepine anxiolytic agent

scientific article

Universal definition of myocardial infarction

scientific article

Variability of cytochrome P450 1A2 activity over time in young and elderly healthy volunteers

scientific article

Wytyczne ESC/ESA dotyczące operacji niekardiochirurgicznych — ocena ryzyka sercowo-naczyniowego i postępowanie w 2014 roku

article

[Guidelines for cardiac pacing and cardiac resynchronization therapy]

scientific article published on 01 May 2008

[Guidelines in cardiac pacing and resynchronization therapy].

scientific article published in December 2007

[Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation]

scientific article published on 01 July 2009

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