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List of works by Albert de Graaf

13C tracer experiments and metabolite balancing for metabolic flux analysis: comparing two approaches

scientific article published in April 1998

A metabolic flux analysis to study the role of sucrose synthase in the regulation of the carbon partitioning in central metabolism in maize root tips

scientific article published on 10 July 2007

A new flexible plug and play scheme for modeling, simulating, and predicting gastric emptying

scientific article published on 10 June 2014

A physiologically-based kinetic model for the prediction of plasma cholesterol concentrations in the mouse

scientific article published on 12 February 2011

A systematic approach to obtain validated partial least square models for predicting lipoprotein subclasses from serum NMR spectra.

scientific article published on 18 December 2013

A universal framework for 13C metabolic flux analysis

scientific article published on 01 July 2001

Accurate determination of 13C enrichments in nonprotonated carbon atoms of isotopically enriched amino acids by 1H nuclear magnetic resonance

scientific article published on 01 February 1997

Beyond diversity: functional microbiomics of the human colon

scientific article published on 10 January 2006

Bidirectional reaction steps in metabolic networks: I. Modeling and simulation of carbon isotope labeling experiments

scientific article published in July 1997

Bidirectional reaction steps in metabolic networks: II. Flux estimation and statistical analysis

scientific article published in July 1997

Bidirectional reaction steps in metabolic networks: III. Explicit solution and analysis of isotopomer labeling systems

scientific article published in January 1999

Bidirectional reaction steps in metabolic networks: IV. Optimal design of isotopomer labeling experiments

scientific article published in January 1999

C3-carboxylation as an anaplerotic reaction in phosphoenolpyruvate carboxylase-deficient Corynebacterium glutamicum

scientific article published on 01 June 1996

Changes of pentose phosphate pathway flux in vivo in Corynebacterium glutamicum during leucine-limited batch cultivation as determined from intracellular metabolite concentration measurements

scientific article published in October 2002

Clustering by plasma lipoprotein profile reveals two distinct subgroups with positive lipid response to fenofibrate therapy

scientific article (publication date: 2012)

Determination of full 13C isotopomer distributions for metabolic flux analysis using heteronuclear spin echo difference NMR spectroscopy

scientific article published on 01 January 2000

Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing

scientific article published in January 1996

Diagnostic markers based on a computational model of lipoprotein metabolism ⬇️

scientific article published on October 26, 2011

Dietary medium chain fatty acid supplementation leads to reduced VLDL lipolysis and uptake rates in comparison to linoleic acid supplementation.

scientific article

Disruption of the SHM2 gene, encoding one of two serine hydroxymethyltransferase isoenzymes, reduces the flux from glycine to serine in Ashbya gossypii.

scientific article published on January 2003

Gaining insight into microbial physiology in the large intestine: a special role for stable isotopes.

scientific article published on January 2008

Identification of glucose-fermenting bacteria present in an in vitro model of the human intestine by RNA-stable isotope probing

scientific article published on 22 February 2007

Kinetic properties of the glucose-6-phosphate and 6-phosphogluconate dehydrogenases from Corynebacterium glutamicum and their application for predicting pentose phosphate pathway flux in vivo

scientific article published on 01 June 2000

Linking phylogenetic identities of bacteria to starch fermentation in an in vitro model of the large intestine by RNA-based stable isotope probing.

scientific article published on 8 December 2008

Lipoprotein metabolism indicators improve cardiovascular risk prediction

scientific article

Metabolic consequences of altered phosphoenolpyruvate carboxykinase activity in Corynebacterium glutamicum reveal anaplerotic regulation mechanisms in vivo

scientific article published in October 2001

Metabolic flux analysis of CHO cells in perfusion culture by metabolite balancing and 2D [13C, 1H] COSY NMR spectroscopy

scientific article published on 5 November 2009

Metabolic phenotype of phosphoglucose isomerase mutants of Corynebacterium glutamicum

scientific article published in September 2003

Nutritional systems biology modeling: from molecular mechanisms to physiology

scientific article

Pathway analysis and metabolic engineering in Corynebacterium glutamicum.

scientific article

Predicting individual responses to pravastatin using a physiologically based kinetic model for plasma cholesterol concentrations

scientific article published on 9 August 2014

Profiling human gut bacterial metabolism and its kinetics using [U-13C]glucose and NMR.

scientific article published in January 2010

Propionate oxidation in Escherichia coli: evidence for operation of a methylcitrate cycle in bacteria.

scientific article

Response of the central metabolism in Corynebacterium glutamicum to the use of an NADH-dependent glutamate dehydrogenase

scientific article published on 01 January 1999

Response of the central metabolism of Corynebacterium glutamicum to different flux burdens

scientific article published in October 1997

Significance of phosphoglucose isomerase for the shift between heterolactic and mannitol fermentation of fructose by Oenococcus oeni

scientific article

The effect of plant sterols and different low doses of omega-3 fatty acids from fish oil on lipoprotein subclasses.

scientific article published on 27 May 2015

The onset of type 2 diabetes: proposal for a multi-scale model.

scientific article published on 31 October 2013

The role of low-grade inflammation and metabolic flexibility in aging and nutritional modulation thereof: a systems biology approach

scientific article published on 23 January 2014

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