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List of works by Cristina Rodríguez-Antona

A Genetic Polymorphism in CTLA-4 Is Associated with Overall Survival in Sunitinib-Treated Patients with Clear Cell Metastatic Renal Cell Carcinoma

scientific article published on 28 February 2018

A Prospective Observational Study for Assessment and Outcome Association of Circulating Endothelial Cells in Clear Cell Renal Cell Carcinoma Patients Who Show Initial Benefit from First-line Treatment. The CIRCLES (CIRCuLating Endothelial cellS) Stu

scientific article

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

article

A novel polymorphic cytochrome P450 formed by splicing of CYP3A7 and the pseudogene CYP3AP1.

scientific article published on 2 June 2005

Advanced sporadic renal epithelioid angiomyolipoma: case report of an extraordinary response to sirolimus linked to TSC2 mutation.

scientific article

Allelic variant at -79 (C>T) in CDKN1B (p27Kip1) confers an increased risk of thyroid cancer and alters mRNA levels.

scientific article

Association between SLC19A1 Gene Polymorphism and High Dose Methotrexate Toxicity in Childhood Acute Lymphoblastic Leukaemia and Non Hodgkin Malignant Lymphoma: Introducing a Haplotype based Approach

scientific article published on 18 September 2017

Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma.

scientific article

Biallelic TSC2 Mutations in a Patient With Chromophobe Renal Cell Carcinoma Showing Extraordinary Response to Temsirolimus

scientific article published on 01 April 2018

CYP2D6 genotyping for psychiatric patients treated with risperidone: considerations for cost-effectiveness studies

scientific article published in April 2009

CYP3A5 and ABCB1 polymorphisms as predictors for sunitinib outcome in metastatic renal cell carcinoma.

scientific article

Characterization of novel CYP2C8 haplotypes and their contribution to paclitaxel and repaglinide metabolism

scientific article published on 9 October 2007

Constitutional genetic variants as predictors of antiangiogenic therapy outcome in renal cell carcinoma.

scientific article

Cytochrome P-450 mRNA Expression in Human Liver and Its Relationship with Enzyme Activity

article

Cytochrome P450 3A5 is highly expressed in normal prostate cells but absent in prostate cancer

scientific article published in September 2007

Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells

scientific article published in June 2002

Cytochrome P450 pharmacogenetics and cancer.

scientific article

DNA Methylation Profiling in Pheochromocytoma and Paraganglioma Reveals Diagnostic and Prognostic Markers

scientific article published on 30 March 2015

Deep sequencing reveals microRNAs predictive of antiangiogenic drug response

scientific article published on 07 July 2016

Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene

scientific article

Description of the EuroTARGET cohort: A European collaborative project on TArgeted therapy in renal cell cancer-GEnetic- and tumor-related biomarkers for response and toxicity.

scientific article published on 3 April 2017

Detection of the first gross CDC73 germline deletion in an HPT-JT syndrome family.

scientific article

Determination of CYP2D6 gene copy number by multiplex polymerase chain reaction analysis

scientific article published on 20 March 2009

Development and validation of the gene-expression Predictor of high-grade-serous Ovarian carcinoma molecular subTYPE (PrOTYPE)

scientific article published on 17 June 2020

Differential gene expression of medullary thyroid carcinoma reveals specific markers associated with genetic conditions

scientific article

Evaluation of KDR rs34231037 as a predictor of sunitinib efficacy in patients with metastatic renal cell carcinoma.

scientific article published on 20 April 2017

Exceptional Response to Temsirolimus in a Metastatic Clear Cell Renal Cell Carcinoma With an Early Novel MTOR-Activating Mutation

scientific article published in November 2017

Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma

scientific article (publication date: 19 June 2011)

Expression of CYP3A4 as a predictor of response to chemotherapy in peripheral T-cell lymphomas

scientific article published on 18 July 2007

Functional and in silico assessment of MAX variants of unknown significance

scientific article

Gain-of-function mutations in DNMT3A in patients with paraganglioma

scientific article published on 08 May 2018

Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

scientific article published on 17 December 2018

Genetic polymorphisms of SCN9A are associated with oxaliplatin-induced neuropathy

scientific article

Genetic variation in the SLC19A1 gene and methotrexate toxicity in rheumatoid arthritis patients.

scientific article

Genetics of pheochromocytoma and paraganglioma in Spanish patients.

scientific article

Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy

scientific journal article

Gross SDHB deletions in patients with paraganglioma detected by multiplex PCR: a possible hot spot?

scientific article published in March 2006

Hematologic β-tubulin VI isoform exhibits genetic variability that influences paclitaxel toxicity.

scientific article

Hsa-miR-139-5p is a prognostic thyroid cancer marker involved in HNRNPF-mediated alternative splicing

scientific article published on 28 August 2019

IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma

scientific article

Identification and phenotype characterization of two CYP3A haplotypes causing different enzymatic capacity in fetal livers

scientific article

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Identification of candidate SNPs for drug induced toxicity from differentially expressed genes in associated tissues

scientific article

Identification of tissue microRNAs predictive of sunitinib activity in patients with metastatic renal cell carcinoma

scientific article published on 24 January 2014

Impact of chemotherapy on telomere length in sporadic and familial breast cancer patients

scientific article published on 21 December 2014

Impact of genetic polymorphisms in CYP2C8 and rosiglitazone intake on the urinary excretion of dihydroxyeicosatrienoic acids

scientific article

Improving pharmacovigilance in Europe: TPMT genotyping and phenotyping in the UK and Spain

scientific article

Influence of RET mutations on the expression of tyrosine kinases in medullary thyroid carcinoma

scientific article published on 12 July 2013

Influence of donor liver CYP3A4*20 loss-of-function genotype on tacrolimus pharmacokinetics in transplanted patients.

scientific article published on 18 December 2017

Integrative analysis of miRNA and mRNA expression profiles in pheochromocytoma and paraganglioma identifies genotype-specific markers and potentially regulated pathways

scientific article published on 24 June 2013

Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix

scientific article published on 01 December 1998

Loss of the actin regulator HSPC300 results in clear cell renal cell carcinoma protection in Von Hippel-Lindau patients

scientific article published on June 2007

Meta-analysis on the association of VEGFR1 genetic variants with sunitinib outcome in metastatic renal cell carcinoma patients

scientific article

Microtubule-Targeting Drugs and Personalization of Cancer Treatment ⬇️

scientific article published on April 1, 2011

Molecular characterisation of a common SDHB deletion in paraganglioma patients.

scientific article published on 5 December 2007

Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics

scientific article published on 26 October 2017

Overexpression and activation of EGFR and VEGFR2 in medullary thyroid carcinomas is related to metastasis.

scientific article

Oxaliplatin induced-neuropathy in digestive tumors

scientific article published on 28 August 2013

PTEN expression and mutations in TSC1, TSC2 and MTOR are associated with response to rapalogs in patients with renal cell carcinoma

scientific article published on 09 August 2019

Pazopanib in pretreated advanced neuroendocrine tumors: a phase II, open-label trial of the Spanish Task Force Group for Neuroendocrine Tumors (GETNE).

scientific article published on 10 June 2015

Pharmacogenomic biomarkers for personalized cancer treatment.

scientific article

Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles

scientific article

PheoSeq: A Targeted Next-Generation Sequencing Assay for Pheochromocytoma and Paraganglioma Diagnostics

scientific article published on 25 May 2017

Polymorphisms associated with everolimus pharmacokinetics, toxicity and survival in metastatic breast cancer

scientific article published on 20 July 2017

Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity

scientific article published on 9 March 2010

Progress in pharmacogenetics: consortiums and new strategies

scientific article

Prospective study assessing hypoxia-related proteins as markers for the outcome of treatment with sunitinib in advanced clear-cell renal cell carcinoma.

scientific article published on 20 June 2013

Quantitative RT-PCR Measurement of Human Cytochrome P-450s: Application to Drug Induction Studies

scientific article published on 01 April 2000

Rationalization of genetic testing in patients with apparently sporadic pheochromocytoma/paraganglioma.

scientific article

Recommendations for somatic and germline genetic testing of single pheochromocytoma and paraganglioma based on findings from a series of 329 patients.

scientific article published on 12 August 2015

Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy.

scientific article published on 20 June 2012

Renal carcinoma pharmacogenomics and predictors of response: Steps toward treatment individualization.

scientific article published on February 2014

Replication of Genetic Polymorphisms Reported to Be Associated with Taxane-Related Sensory Neuropathy in Patients with Early Breast Cancer Treated with Paclitaxel--letter.

scientific article

Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas

scientific article

Role of MDH2 pathogenic variant in pheochromocytoma and paraganglioma patients

scientific article published on 16 July 2018

Role of cytochrome P450 2C8*3 (CYP2C8*3) in paclitaxel metabolism and paclitaxel-induced neurotoxicity.

scientific article

SDHC mutation in an elderly patient without familial antecedents.

scientific article

SNPs associated with activity and toxicity of cabazitaxel in patients with advanced urothelial cell carcinoma

scientific article published on 29 March 2016

Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study

article

Sunitinib and Evofosfamide (TH-302) in Systemic Treatment-Naïve Patients with Grade 1/2 Metastatic Pancreatic Neuroendocrine Tumors: The GETNE-1408 Trial

scientific article published on 14 July 2021

Sunitinib-induced hypertension in CYP3A4 rs4646437 A-allele carriers with metastatic renal cell carcinoma.

scientific article published on 26 January 2016

Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy.

scientific article published on 31 August 2016

The hematopoietic-specific beta1-tubulin is naturally resistant to 2-methoxyestradiol and protects patients from drug-induced myelosuppression

scientific article published on 16 December 2009

The miR-200 family controls -tubulin III expression and is associated with paclitaxel-based treatment response and progression-free survival in ovarian cancer patients

scientific article published on 21 December 2010

The role of pharmacogenetics and pharmacogenomics in 21st-century medicine: state of the art and new challenges discussed in the VII Conference of the Spanish Pharmacogenetics and Pharmacogenomics Society (SEFF)

scientific article published on 01 March 2016

The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors

scientific article published on 4 September 2009

Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma

scientific article

Tumoral EPAS1 (HIF2A) mutations explain sporadic pheochromocytoma and paraganglioma in the absence of erythrocytosis

scientific article published on 14 February 2013

Tumoral and tissue-specific expression of the major human beta-tubulin isotypes

scientific article

VEGF, VEGFR3, and PDGFRB protein expression is influenced by RAS mutations in medullary thyroid carcinoma

scientific article

Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene.

scientific article

mTOR Pathway Mutations and Response to Rapalogs in RCC-Letter.

scientific article published in September 2017

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