List of works - Mitsuhiro Nakamura

A highly sensitive assay for ritodrine in human serum by hydrophilic interaction chromatography-tandem mass spectrometry

scientific article published on 19 November 2007

A simple and rapid determination of valproic acid in human plasma using a non-porous silica column and liquid chromatography with tandem mass spectrometric detection

scientific article

Accidental etizolam ingestion in a child

scientific article

Adenylyl cyclase-cAMP system inhibits thrombin-induced HSP27 in vascular smooth muscle cells

scientific article

Adverse Event Trends Associated with OTC Analgesic and Antipyretic Drug: Data Mining of the Japanese Adverse Drug Event Report Database

scientific article published in January 2017

Adverse Event Trends Associated with Over-the-counter Combination Cold Remedy: Data Mining of the Japanese Adverse Drug Event Report Database

scientific article published in January 2018

Adverse Event Trends Associated with Over-the-counter Drugs: Data Mining of the Japanese Adverse Drug Event Report Database

scientific article

Adverse event profiles of ifosfamide-induced encephalopathy analyzed using the Food and Drug Administration Adverse Event Reporting System and the Japanese Adverse Drug Event Report databases

scientific article published on 09 September 2019

Adverse event profiles of solvent-based and nanoparticle albumin-bound paclitaxel formulations using the Food and Drug Administration Adverse Event Reporting System

scientific article published on 11 March 2019

Adverse events of smoking cessation treatments (nicotine replacement therapy and non-nicotine prescription medication) and electronic cigarettes in the Food and Drug Administration Adverse Event Reporting System, 2004-2016.

scientific article

Adverse reaction profiles of hemorrhagic adverse reactions caused by direct oral anticoagulants analyzed using the Food and Drug Administration Adverse Event Reporting System (FAERS) database and the Japanese Adverse Drug Event Report (JADER) databa

scientific article published on 07 September 2019

Age-related trends in injection site reaction incidence induced by the tumor necrosis factor-α (TNF-α) inhibitors etanercept and adalimumab: the Food and Drug Administration adverse event reporting system, 2004-2015.

scientific article published on 15 January 2017

Albumin-bilirubin score for predicting neuropsychiatric symptoms in patients receiving ifosfamide-based chemotherapy

scientific article published on 04 January 2021

Alcohol-induced impaired insulin secretion in a Japanese population: Five-year follow-up in the Gifu Diabetes Study

scientific article published on 29 March 2020

Analyses of benzodiazepines and their metabolites in various biological matrices by LC-MS(/MS) ⬇️

scientific article published on March 14, 2011

Analysis of Neuropsychiatric Adverse Events in Patients Treated with Oseltamivir in Spontaneous Adverse Event Reports.

scientific article

Analysis of Stevens-Johnson syndrome and toxic epidermal necrolysis using the Japanese Adverse Drug Event Report database.

scientific article published on 21 June 2016

Analysis of adverse events of renal impairment related to platinum-based compounds using the Japanese Adverse Drug Event Report database.

scientific article

Analysis of drug-induced hearing loss by using a spontaneous reporting system database

scientific article published on 08 October 2019

Analysis of drug-induced interstitial lung disease using the Japanese Adverse Drug Event Report database

scientific article published on 06 May 2020

Analysis of fall-related adverse events among older adults using the Japanese Adverse Drug Event Report (JADER) database

scientific article published on 17 December 2018

Analysis of immune-related adverse events caused by immune checkpoint inhibitors using the Japanese Adverse Drug Event Report database

scientific article published on 01 September 2020

Analysis of polypharmacy effects in older patients using Japanese Adverse Drug Event Report database

scientific article published on 21 December 2017

Analysis of the Interaction between Clopidogrel, Aspirin, and Proton Pump Inhibitors Using the FDA Adverse Event Reporting System Database

scientific article published in January 2015

Analysis of the time-to-onset of osteonecrosis of jaw with bisphosphonate treatment using the data from a spontaneous reporting system of adverse drug events

scientific article published on 22 December 2015

Association between Selective Serotonin Reuptake Inhibitor Therapy and Suicidality: Analysis of U.S. Food and Drug Administration Adverse Event Reporting System Data.

scientific article

Body Surface Area Formulas for the Calculation of the Chemotherapy Dosage

scientific article published in November 2017

Chinese-Named Entity Recognition From Adverse Drug Event Records: Radical Embedding-Combined Dynamic Embedding-Based BERT in a Bidirectional Long Short-term Conditional Random Field (Bi-LSTM-CRF) Model

scientific article published on 01 December 2021

Comparison of the adverse event profiles of conventional and liposomal formulations of doxorubicin using the FDA adverse event reporting system.

scientific article published on 27 September 2017

Contact allergy to liquorice flavonoids: analysis with liquid chromatography-mass spectrometry

scientific article published on 01 March 2016

Contraceptives as possible risk factors for postpartum depression: A retrospective study of the food and drug administration adverse event reporting system, 2004-2015.

scientific article

Development of computer-assisted biohazard safety cabinet for preparation and verification of injectable anticancer agents.

scientific article

Drug-induced gingival hyperplasia: a retrospective study using spontaneous reporting system databases

scientific article published on 19 July 2017

Effect of wortmannin and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) on N-formyl-methionyl-leucyl-phenylalanine-induced phospholipase D activation in differentiated HL60 cells: possible involvement of phosphatidylinositol 3-kinase in

scientific article published on 01 June 1997

Effects of 14 frequently used drugs on prostate-specific antigen expression in prostate cancer LNCaP cells.

scientific article published on 05 March 2014

Effects of selective phosphodiesterase type IV inhibitor, rolipram, on signal transducing phospholipases in neutrophil: inhibition of phospholipases A2, D but not C

scientific article published on 01 October 1995

Efficacy and safety of micafungin for treating febrile neutropenia in hematological malignancies.

scientific article published on November 2010

Evaluation of Dabigatran- and Warfarin-Associated Hemorrhagic Events Using the FDA-Adverse Event Reporting System Database Stratified by Age

scientific article

Evaluation of Drug-Induced Photosensitivity Using the Japanese Adverse Drug Event Report (JADER) Database

scientific article published in January 2017

Evaluation of pregabalin-induced adverse events related to falls using the FDA adverse event reporting system and Japanese Adverse Drug Event Report databases

scientific article published on 19 December 2018

Evaluation of the Association of Hand-Foot Syndrome with Anticancer Drugs Using the US Food and Drug Administration Adverse Event Reporting System (FAERS) and Japanese Adverse Drug Event Report (JADER) Databases

scientific article

Evaluation of the association between the use of oral anti-hyperglycemic agents and hypoglycemia in Japan by data mining of the Japanese Adverse Drug Event Report (JADER) database

scientific article

Gentamicin-induced hearing loss: A retrospective study using the Food and Drug Administration Adverse Event Reporting System and a toxicological study using drug-gene network analysis

scientific article published on 29 June 2021

High-performance liquid chromatographic assay of clonazepam in human plasma using a non-porous silica column

scientific article

High-performance liquid chromatographic assay of zonisamide in human plasma using a non-porous silica column.

scientific article published in May 2001

Hyperglycemic adverse events following antipsychotic drug administration in spontaneous adverse event reports.

scientific article published on 16 April 2015

Hypergravity exposure for 14 days increases the effects of propofol in rats

scientific article published in January 2014

IFN- Reduces Epidermal Barrier Function by Affecting Fatty Acid Composition of Ceramide in a Mouse Atopic Dermatitis Model

article

Increased SPHK2 Transcription of Human Colon Cancer Cells in Serum-Depleted Culture: The Involvement of CREB Transcription Factor

scientific article published on 24 March 2015

Increased acid ceramidase expression depends on upregulation of androgen-dependent deubiquitinases, USP2, in a human prostate cancer cell line, LNCaP.

scientific article

Interferon-γ decreases ceramides with long-chain fatty acids: possible involvement in atopic dermatitis and psoriasis

scientific article published on 05 September 2013

Involvement of Mincle and Syk in the changes to innate immunity after ischemic stroke

scientific article

Involvement of tyrosine phosphorylation in inhibition of fMLP-induced PLD activation by N-acetyl-L-cysteine in differentiated HL60 cells

scientific article published in June 1998

Isolation of multiple forms of indanol dehydrogenase associated with 17 beta-hydroxysteroid dehydrogenase activity from male rabbit liver

scientific article published on 01 August 1986

Monkey liver indanol dehydrogenase. Purification, properties, and kinetic mechanism

scientific article published in July 1989

Pediatric thioridazine poisoning as a result of a pharmacy compounding error.

scientific article published on 8 June 2009

Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells.

scientific article published on 22 January 2016

Role of down-regulated neutral ceramidase during all-trans retinoic acid-induced neuronal differentiation in SH-SY5Y neuroblastoma cells

scientific article published on 26 March 2012

Significant differences in drug lag in clinical development among various strategies used for regulatory submissions in Japan

scientific article

Simultaneous determination of benzodiazepines and their metabolites in human serum by liquid chromatography-tandem mass spectrometry using a high-resolution octadecyl silica column compatible with aqueous compounds

scientific article

Sphingosine kinase 1 expression is downregulated during differentiation of Friend cells due to decreased c-MYB.

scientific article published on 14 January 2013

Sphingosine kinase 1 plays a role in the upregulation of CD44 expression through extracellular signal-regulated kinase signaling in human colon cancer cells.

scientific article published on June 2013

Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation.

scientific article

Stevens-Johnson syndrome and toxic epidermal necrolysis: the Food and Drug Administration adverse event reporting system, 2004-2013.

scientific article published on 7 February 2015

Survey of Description on Package Inserts of OTC Drugs

scientific article published in January 2018

Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape

scientific article published on 02 July 2019

Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells.

scientific article

The mRNA overexpression of inflammatory enzymes, phospholipase A2 and cyclooxygenase, in the large bowel mucosa and neoplasms of F344 rats treated with naturally occurring carcinogen, 1-hydroxyanthraquinone

scientific article

The pivotal role of intracellular calcium in oxaliplatin-induced inhibition of neurite outgrowth but not cell death in differentiated PC12 cells.

scientific article published on 19 October 2011

Theophylline-associated status epilepticus in an infant: pharmacokinetics and the risk of suppository use.

scientific article published on 13 November 2009

Thromboembolic adverse event study of combined estrogen-progestin preparations using Japanese Adverse Drug Event Report database.

scientific article published on 21 July 2017

Time-to-Onset Analysis of Drug-Induced Long QT Syndrome Based on a Spontaneous Reporting System for Adverse Drug Events

scientific article

Transcriptional regulation of neutral sphingomyelinase 2 in all-trans retinoic acid-treated human breast cancer cell line, MCF-7.

scientific article

Tyrosine phosphorylation and activation of mitogen-activated protein kinases by thrombin in human platelets: possible involvement in late arachidonic acid release

scientific article published on 01 January 1994

[Analysis of Spontaneously Reported Adverse Events]

scientific article published on 01 January 2016

[Contribution of the pharmacists to self-care and primary care with nonprescription medications]

scientific article published on 01 December 2010

[Future Vision of Regulatory Science in the Global Development of Pharmaceuticals and Medical Devices]

scientific article published on 01 January 2016

[Survey of Label Information of Foods with Function Claims]

scientific article published on 01 January 2020

[Survey of the Distribution of Community Pharmacists Using Government Statistics]

scientific article published on 01 January 2018

List of works by Mitsuhiro Nakamura

A highly sensitive assay for ritodrine in human serum by hydrophilic interaction chromatography-tandem mass spectrometry

A simple and rapid determination of valproic acid in human plasma using a non-porous silica column and liquid chromatography with tandem mass spectrometric detection

Accidental etizolam ingestion in a child

Adenylyl cyclase-cAMP system inhibits thrombin-induced HSP27 in vascular smooth muscle cells

Adverse Event Trends Associated with OTC Analgesic and Antipyretic Drug: Data Mining of the Japanese Adverse Drug Event Report Database

Adverse Event Trends Associated with Over-the-counter Combination Cold Remedy: Data Mining of the Japanese Adverse Drug Event Report Database

Adverse Event Trends Associated with Over-the-counter Drugs: Data Mining of the Japanese Adverse Drug Event Report Database

Adverse event profiles of ifosfamide-induced encephalopathy analyzed using the Food and Drug Administration Adverse Event Reporting System and the Japanese Adverse Drug Event Report databases

Adverse event profiles of solvent-based and nanoparticle albumin-bound paclitaxel formulations using the Food and Drug Administration Adverse Event Reporting System

Adverse events of smoking cessation treatments (nicotine replacement therapy and non-nicotine prescription medication) and electronic cigarettes in the Food and Drug Administration Adverse Event Reporting System, 2004-2016.

Adverse reaction profiles of hemorrhagic adverse reactions caused by direct oral anticoagulants analyzed using the Food and Drug Administration Adverse Event Reporting System (FAERS) database and the Japanese Adverse Drug Event Report (JADER) databa

Age-related trends in injection site reaction incidence induced by the tumor necrosis factor-α (TNF-α) inhibitors etanercept and adalimumab: the Food and Drug Administration adverse event reporting system, 2004-2015.

Albumin-bilirubin score for predicting neuropsychiatric symptoms in patients receiving ifosfamide-based chemotherapy

Alcohol-induced impaired insulin secretion in a Japanese population: Five-year follow-up in the Gifu Diabetes Study

Analyses of benzodiazepines and their metabolites in various biological matrices by LC-MS(/MS) ⬇️

Analysis of Neuropsychiatric Adverse Events in Patients Treated with Oseltamivir in Spontaneous Adverse Event Reports.

Analysis of Stevens-Johnson syndrome and toxic epidermal necrolysis using the Japanese Adverse Drug Event Report database.

Analysis of adverse events of renal impairment related to platinum-based compounds using the Japanese Adverse Drug Event Report database.

Analysis of drug-induced hearing loss by using a spontaneous reporting system database

Analysis of drug-induced interstitial lung disease using the Japanese Adverse Drug Event Report database

Analysis of fall-related adverse events among older adults using the Japanese Adverse Drug Event Report (JADER) database

Analysis of immune-related adverse events caused by immune checkpoint inhibitors using the Japanese Adverse Drug Event Report database

Analysis of polypharmacy effects in older patients using Japanese Adverse Drug Event Report database

Analysis of the Interaction between Clopidogrel, Aspirin, and Proton Pump Inhibitors Using the FDA Adverse Event Reporting System Database

Analysis of the time-to-onset of osteonecrosis of jaw with bisphosphonate treatment using the data from a spontaneous reporting system of adverse drug events

Association between Selective Serotonin Reuptake Inhibitor Therapy and Suicidality: Analysis of U.S. Food and Drug Administration Adverse Event Reporting System Data.

Body Surface Area Formulas for the Calculation of the Chemotherapy Dosage

Chinese-Named Entity Recognition From Adverse Drug Event Records: Radical Embedding-Combined Dynamic Embedding-Based BERT in a Bidirectional Long Short-term Conditional Random Field (Bi-LSTM-CRF) Model

Comparison of the adverse event profiles of conventional and liposomal formulations of doxorubicin using the FDA adverse event reporting system.

Contact allergy to liquorice flavonoids: analysis with liquid chromatography-mass spectrometry

Contraceptives as possible risk factors for postpartum depression: A retrospective study of the food and drug administration adverse event reporting system, 2004-2015.

Development of computer-assisted biohazard safety cabinet for preparation and verification of injectable anticancer agents.

Drug-induced gingival hyperplasia: a retrospective study using spontaneous reporting system databases

Effect of wortmannin and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) on N-formyl-methionyl-leucyl-phenylalanine-induced phospholipase D activation in differentiated HL60 cells: possible involvement of phosphatidylinositol 3-kinase in

Effects of 14 frequently used drugs on prostate-specific antigen expression in prostate cancer LNCaP cells.

Effects of selective phosphodiesterase type IV inhibitor, rolipram, on signal transducing phospholipases in neutrophil: inhibition of phospholipases A2, D but not C

Efficacy and safety of micafungin for treating febrile neutropenia in hematological malignancies.

Evaluation of Dabigatran- and Warfarin-Associated Hemorrhagic Events Using the FDA-Adverse Event Reporting System Database Stratified by Age

Evaluation of Drug-Induced Photosensitivity Using the Japanese Adverse Drug Event Report (JADER) Database

Evaluation of pregabalin-induced adverse events related to falls using the FDA adverse event reporting system and Japanese Adverse Drug Event Report databases

Evaluation of the Association of Hand-Foot Syndrome with Anticancer Drugs Using the US Food and Drug Administration Adverse Event Reporting System (FAERS) and Japanese Adverse Drug Event Report (JADER) Databases

Evaluation of the association between the use of oral anti-hyperglycemic agents and hypoglycemia in Japan by data mining of the Japanese Adverse Drug Event Report (JADER) database

Gentamicin-induced hearing loss: A retrospective study using the Food and Drug Administration Adverse Event Reporting System and a toxicological study using drug-gene network analysis

High-performance liquid chromatographic assay of clonazepam in human plasma using a non-porous silica column

High-performance liquid chromatographic assay of zonisamide in human plasma using a non-porous silica column.

Hyperglycemic adverse events following antipsychotic drug administration in spontaneous adverse event reports.

Hypergravity exposure for 14 days increases the effects of propofol in rats

IFN- Reduces Epidermal Barrier Function by Affecting Fatty Acid Composition of Ceramide in a Mouse Atopic Dermatitis Model

Increased SPHK2 Transcription of Human Colon Cancer Cells in Serum-Depleted Culture: The Involvement of CREB Transcription Factor

Increased acid ceramidase expression depends on upregulation of androgen-dependent deubiquitinases, USP2, in a human prostate cancer cell line, LNCaP.

Interferon-γ decreases ceramides with long-chain fatty acids: possible involvement in atopic dermatitis and psoriasis

Involvement of Mincle and Syk in the changes to innate immunity after ischemic stroke

Involvement of tyrosine phosphorylation in inhibition of fMLP-induced PLD activation by N-acetyl-L-cysteine in differentiated HL60 cells

Isolation of multiple forms of indanol dehydrogenase associated with 17 beta-hydroxysteroid dehydrogenase activity from male rabbit liver

Monkey liver indanol dehydrogenase. Purification, properties, and kinetic mechanism

Pediatric thioridazine poisoning as a result of a pharmacy compounding error.

Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells.

Role of down-regulated neutral ceramidase during all-trans retinoic acid-induced neuronal differentiation in SH-SY5Y neuroblastoma cells

Significant differences in drug lag in clinical development among various strategies used for regulatory submissions in Japan

Simultaneous determination of benzodiazepines and their metabolites in human serum by liquid chromatography-tandem mass spectrometry using a high-resolution octadecyl silica column compatible with aqueous compounds

Sphingosine kinase 1 expression is downregulated during differentiation of Friend cells due to decreased c-MYB.

Sphingosine kinase 1 plays a role in the upregulation of CD44 expression through extracellular signal-regulated kinase signaling in human colon cancer cells.

Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation.

Stevens-Johnson syndrome and toxic epidermal necrolysis: the Food and Drug Administration adverse event reporting system, 2004-2013.

Survey of Description on Package Inserts of OTC Drugs

Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape

Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells.

The mRNA overexpression of inflammatory enzymes, phospholipase A2 and cyclooxygenase, in the large bowel mucosa and neoplasms of F344 rats treated with naturally occurring carcinogen, 1-hydroxyanthraquinone

The pivotal role of intracellular calcium in oxaliplatin-induced inhibition of neurite outgrowth but not cell death in differentiated PC12 cells.

Theophylline-associated status epilepticus in an infant: pharmacokinetics and the risk of suppository use.

Thromboembolic adverse event study of combined estrogen-progestin preparations using Japanese Adverse Drug Event Report database.

Time-to-Onset Analysis of Drug-Induced Long QT Syndrome Based on a Spontaneous Reporting System for Adverse Drug Events

Transcriptional regulation of neutral sphingomyelinase 2 in all-trans retinoic acid-treated human breast cancer cell line, MCF-7.

Tyrosine phosphorylation and activation of mitogen-activated protein kinases by thrombin in human platelets: possible involvement in late arachidonic acid release

[Analysis of Spontaneously Reported Adverse Events]

[Contribution of the pharmacists to self-care and primary care with nonprescription medications]

[Future Vision of Regulatory Science in the Global Development of Pharmaceuticals and Medical Devices]

[Survey of Label Information of Foods with Function Claims]

[Survey of the Distribution of Community Pharmacists Using Government Statistics]