List of works - Esa R Korpi

AMPA/kainate receptor-mediated up-regulation of GABAA receptor delta subunit mRNA expression in cultured rat cerebellar granule cells is dependent on NMDA receptor activation.

scientific article

Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit.

scientific article

Actions of two GABAA receptor benzodiazepine-site ligands that are mediated via non-γ2-dependent modulation

scientific article published on 19 May 2011

Acute Effects of Ethanol on Glutamate Receptors ⬇️

scientific article published on April 21, 2012

Acute effects of AMPA-type glutamate receptor antagonists on intermale social behavior in two mouse lines bidirectionally selected for offensive aggression

scientific article published on 01 May 2007

Addiction-related interactions of pregabalin with morphine in mice and humans: reinforcing and inhibiting effects.

scientific article published on 25 July 2017

Agonist occupancy is essential for forward trafficking of AMPA receptors

scientific article

Agonistic effects of the beta-carboline DMCM revealed in GABA(A) receptor gamma 2 subunit F77I point-mutated mice

scientific article (publication date: March 2005)

Alpha 1 subunit-containing GABA type A receptors in forebrain contribute to the effect of inhaled anesthetics on conditioned fear

scientific article published on 15 April 2005

Analysis of the potential role of GluA4 carboxyl-terminus in PDZ interactions

scientific article

Attenuation of Novelty-Induced Hyperactivity of Mice by Cannabidiol and Hippocampal Inhibitory Chemogenetics

scientific article published on 29 March 2019

Autoinactivation of the stargazin-AMPA receptor complex: subunit-dependency and independence from physical dissociation

scientific article

Autoradiographic imaging of altered synaptic alphabetagamma2 and extrasynaptic alphabeta GABAA receptors in a genetic mouse model of anxiety

scientific article

Behavioural correlates of an altered balance between synaptic and extrasynaptic GABAAergic inhibition in a mouse model.

scientific article published in October 2004

Characterization of gamma-aminobutyrate type A receptors with atypical coupling between agonist and convulsant binding sites in discrete brain regions.

scientific article

Chronic treatment with mood-stabilizers attenuates abnormal hyperlocomotion of GluA1-subunit deficient mice

scientific article (publication date: 2014)

Compensation by reduced L-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor responses in a mouse model with reduced gamma-aminobutyric acid type A receptor-mediated synaptic inhibition

scientific article published in February 2007

Conditioned Aversion and Neuroplasticity Induced by a Superagonist of Extrasynaptic GABAA Receptors: Correlation With Activation of the Oval BNST Neurons and CRF Mechanisms

scientific article published on 24 May 2019

Conditioned Reward of Opioids, but not Psychostimulants, is Impaired in GABA-A Receptor δ Subunit Knockout Mice

scientific article published on 09 July 2018

Continuous delivery of naltrexone and nalmefene leads to tolerance in reducing alcohol drinking and to supersensitivity of brain opioid receptors

scientific article

Diazepam-induced neuronal plasticity attenuates locomotor responses to morphine and amphetamine challenges in mice.

scientific article published on 18 July 2011

Does ethanol act preferentially via selected brain GABAA receptor subtypes? the current evidence is ambiguous.

scientific article published on May 2007

Dopaminergic-GABAergic interplay and alcohol binge drinking

scientific article published on 12 January 2019

Electrophysiological Properties of Neurons: Current-Clamp Recordings in Mouse Brain Slices and Firing-Pattern Analysis

publication published on 20 June 2021

Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors

scientific article published on 16 November 2007

Ethanol increases desensitization of recombinant GluR-D AMPA receptor and TARP combinations.

scientific article published on June 2009

Evidence for a role of inhibition of orexinergic neurons in the anxiolytic and sedative effects of diazepam: A c-Fos study

scientific article

Excessive novelty-induced c-Fos expression and altered neurogenesis in the hippocampus of GluA1 knockout mice

scientific article

Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics

scientific article

Finnish neuroscience from past to present

scientific article published on 03 February 2020

From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors.

scientific article

GABA site agonist gaboxadol induces addiction-predicting persistent changes in ventral tegmental area dopamine neurons but is not rewarding in mice or baboons

scientific article

GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics

scientific article

GABAB receptor positive allosteric modulators with different efficacies affect neuroadaptation to and self-administration of alcohol and cocaine

scientific article published on 13 November 2018

GABAergic signalling in the immune system.

scientific article

Gene expression alterations in the cerebellum and granule neurons of Cstb(-/-) mouse are associated with early synaptic changes and inflammation

scientific article

Heterogeneous somatostatin-expressing neuron population in mouse ventral tegmental area

scientific article published on 04 August 2020

Histamine and H3 receptor-dependent mechanisms regulate ethanol stimulation and conditioned place preference in mice

scientific article published on 13 November 2009

Human locus coeruleus neurons express the GABA(A) receptor gamma2 subunit gene and produce benzodiazepine binding

scientific article published on 22 April 2010

Impact of epsilon and theta subunits on pharmacological properties of alpha3beta1 GABAA receptors expressed in Xenopus oocytes

scientific article published on 13 January 2006

Importance of GluA1 subunit-containing AMPA glutamate receptors for morphine state-dependency

scientific article

Increased Motor-Impairing Effects of the Neuroactive Steroid Pregnanolone in Mice with Targeted Inactivation of the GABAA Receptor γ2 Subunit in the Cerebellum.

scientific article published on 27 October 2016

Isoform-specific early trafficking of AMPA receptor flip and flop variants.

scientific article published in October 2006

Kainic acid-induced status epilepticus alters GABA receptor subunit mRNA and protein expression in the developing rat hippocampus.

scientific article published on 30 June 2005

Keto amphetamine toxicity-focus on the redox reactivity of the cathinone designer drug mephedrone.

scientific article

Lifelong ethanol consumption and brain regional GABAA receptor subunit mRNA expression in alcohol-preferring rats

scientific article

Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors

scientific article published on 13 September 2010

Long-lasting modulation of glutamatergic transmission in VTA dopamine neurons after a single dose of benzodiazepine agonists

scientific article published on 18 June 2008

Long-term cognitive and neurochemical effects of "bath salt" designer drugs methylone and mephedrone.

scientific article published on 22 October 2012

Loss of zolpidem efficacy in the hippocampus of mice with the GABAA receptor gamma2 F77I point mutation

scientific article published in June 2005

Manganese-enhanced magnetic resonance imaging reveals differential long-term neuroadaptation after methamphetamine and the substituted cathinone 4-methylmethcathinone (mephedrone).

scientific article published on 7 December 2014

Maturation of cultured hippocampal slices results in increased excitability in granule cells

scientific article published in February 2005

Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse.

scientific article

Methadone increases intracellular calcium in SH-SY5Y and SH-EP1-halpha7 cells by activating neuronal nicotinic acetylcholine receptors

scientific article published on 5 July 2005

Mitochondrial respiratory dysfunction due to the conversion of substituted cathinones to methylbenzamides in SH-SY5Y cells

scientific article published on 14 October 2015

Modifying the subunit composition of TASK channels alters the modulation of a leak conductance in cerebellar granule neurons.

scientific article published in December 2005

Morphine-nicotine interaction in conditioned place preference in mice after chronic nicotine exposure

scientific article published in April 2008

Multimetric statistical analysis of behavior in mice selected for high and low levels of isolation-induced male aggression.

scientific article

Multiple actions of fenamates and other nonsteroidal anti-inflammatory drugs on GABAA receptors

scientific article published on 28 March 2019

Neurosteroid Agonist at GABAA receptor induces persistent neuroplasticity in VTA dopamine neurons

scientific article published on 27 September 2013

Neurotoxicity of Ammonia.

scientific article

Normal extinction and reinstatement of morphine-induced conditioned place preference in the GluA1-KO mouse line

scientific article published on 01 August 2019

Paradoxical widespread c-Fos expression induced by a GABA agonist in the forebrain of transgenic mice with ectopic expression of the GABA(A) α6 subunit

scientific article published on 9 March 2015

Prototypic GABA(A) receptor agonist muscimol acts preferentially through forebrain high-affinity binding sites.

scientific article

RFamide-related peptides signal through the neuropeptide FF receptor and regulate pain-related responses in the rat.

scientific article published in January 2005

Reduced benzodiazepine tolerance, but increased flumazenil-precipitated withdrawal in AMPA-receptor GluR-A subunit-deficient mice

scientific article published on 24 December 2008

Regulation of GABA(A) receptor subunit expression by pharmacological agents.

scientific article

Removal of GABA(A) receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations

scientific article

Reversal of novelty-induced hippocampal c-Fos expression in GluA1 subunit-deficient mice by chronic treatment targeting glutamatergic transmission

scientific article published on 18 October 2014

Reversal of novelty-induced hyperlocomotion and hippocampal c-Fos expression in GluA1 knockout male mice by the mGluR2/3 agonist LY354740.

scientific article published on 15 July 2013

Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through αβγ2-type GABA(A) Receptors.

scientific article

Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics

scientific article published on January 2011

Selective increases of AMPA, NMDA, and kainate receptor subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics

scientific article published on 29 January 2014

Selective reduction of gamma-aminobutyric acid type A receptor delta subunit mRNA levels by MK-801 in rat dentate gyrus

scientific article

Simo S. Oja--amino acids all along as building blocks of brain and life

scientific article published in December 2005

TASK-3 knockout mice exhibit exaggerated nocturnal activity, impairments in cognitive functions, and reduced sensitivity to inhalation anesthetics

scientific article published on 17 September 2007

The alpha2-adrenoceptor antagonist atipamezole reduces the development and expression of d-amphetamine-induced behavioural sensitization

scientific article published on 14 February 2003

The impact of sub-cellular location and intracellular neuronal proteins on properties of GABA(A) receptors.

scientific article published on January 2007

The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists.

scientific article published on 5 January 2006

Use of MGLUR2 and MGLUR3 knockout mice to explore in vivo receptor specificity of the MGLUR2/3 selective antagonist LY341495.

scientific article published on 27 May 2009

Xenon does not affect gamma-aminobutyric acid type A receptor binding in humans

scientific article published in January 2008

alpha(2A)-Adrenoceptors regulate d-amphetamine-induced hyperactivity and behavioural sensitization in mice

scientific article published in July 2005

List of works by Esa R Korpi

AMPA/kainate receptor-mediated up-regulation of GABAA receptor delta subunit mRNA expression in cultured rat cerebellar granule cells is dependent on NMDA receptor activation.

Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit.

Actions of two GABAA receptor benzodiazepine-site ligands that are mediated via non-γ2-dependent modulation

Acute Effects of Ethanol on Glutamate Receptors ⬇️

Acute effects of AMPA-type glutamate receptor antagonists on intermale social behavior in two mouse lines bidirectionally selected for offensive aggression

Addiction-related interactions of pregabalin with morphine in mice and humans: reinforcing and inhibiting effects.

Agonist occupancy is essential for forward trafficking of AMPA receptors

Agonistic effects of the beta-carboline DMCM revealed in GABA(A) receptor gamma 2 subunit F77I point-mutated mice

Alpha 1 subunit-containing GABA type A receptors in forebrain contribute to the effect of inhaled anesthetics on conditioned fear

Analysis of the potential role of GluA4 carboxyl-terminus in PDZ interactions

Attenuation of Novelty-Induced Hyperactivity of Mice by Cannabidiol and Hippocampal Inhibitory Chemogenetics

Autoinactivation of the stargazin-AMPA receptor complex: subunit-dependency and independence from physical dissociation

Autoradiographic imaging of altered synaptic alphabetagamma2 and extrasynaptic alphabeta GABAA receptors in a genetic mouse model of anxiety

Behavioural correlates of an altered balance between synaptic and extrasynaptic GABAAergic inhibition in a mouse model.

Characterization of gamma-aminobutyrate type A receptors with atypical coupling between agonist and convulsant binding sites in discrete brain regions.

Chronic treatment with mood-stabilizers attenuates abnormal hyperlocomotion of GluA1-subunit deficient mice

Compensation by reduced L-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor responses in a mouse model with reduced gamma-aminobutyric acid type A receptor-mediated synaptic inhibition

Conditioned Aversion and Neuroplasticity Induced by a Superagonist of Extrasynaptic GABAA Receptors: Correlation With Activation of the Oval BNST Neurons and CRF Mechanisms

Conditioned Reward of Opioids, but not Psychostimulants, is Impaired in GABA-A Receptor δ Subunit Knockout Mice

Continuous delivery of naltrexone and nalmefene leads to tolerance in reducing alcohol drinking and to supersensitivity of brain opioid receptors

Diazepam-induced neuronal plasticity attenuates locomotor responses to morphine and amphetamine challenges in mice.

Does ethanol act preferentially via selected brain GABAA receptor subtypes? the current evidence is ambiguous.

Dopaminergic-GABAergic interplay and alcohol binge drinking

Electrophysiological Properties of Neurons: Current-Clamp Recordings in Mouse Brain Slices and Firing-Pattern Analysis

Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors

Ethanol increases desensitization of recombinant GluR-D AMPA receptor and TARP combinations.

Evidence for a role of inhibition of orexinergic neurons in the anxiolytic and sedative effects of diazepam: A c-Fos study

Excessive novelty-induced c-Fos expression and altered neurogenesis in the hippocampus of GluA1 knockout mice

Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics

Finnish neuroscience from past to present

From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors.

GABA site agonist gaboxadol induces addiction-predicting persistent changes in ventral tegmental area dopamine neurons but is not rewarding in mice or baboons

GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics

GABAB receptor positive allosteric modulators with different efficacies affect neuroadaptation to and self-administration of alcohol and cocaine

GABAergic signalling in the immune system.

Gene expression alterations in the cerebellum and granule neurons of Cstb(-/-) mouse are associated with early synaptic changes and inflammation

Heterogeneous somatostatin-expressing neuron population in mouse ventral tegmental area

Histamine and H3 receptor-dependent mechanisms regulate ethanol stimulation and conditioned place preference in mice

Human locus coeruleus neurons express the GABA(A) receptor gamma2 subunit gene and produce benzodiazepine binding

Impact of epsilon and theta subunits on pharmacological properties of alpha3beta1 GABAA receptors expressed in Xenopus oocytes

Importance of GluA1 subunit-containing AMPA glutamate receptors for morphine state-dependency

Increased Motor-Impairing Effects of the Neuroactive Steroid Pregnanolone in Mice with Targeted Inactivation of the GABAA Receptor γ2 Subunit in the Cerebellum.

Isoform-specific early trafficking of AMPA receptor flip and flop variants.

Kainic acid-induced status epilepticus alters GABA receptor subunit mRNA and protein expression in the developing rat hippocampus.

Keto amphetamine toxicity-focus on the redox reactivity of the cathinone designer drug mephedrone.

Lifelong ethanol consumption and brain regional GABAA receptor subunit mRNA expression in alcohol-preferring rats

Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors

Long-lasting modulation of glutamatergic transmission in VTA dopamine neurons after a single dose of benzodiazepine agonists

Long-term cognitive and neurochemical effects of "bath salt" designer drugs methylone and mephedrone.

Loss of zolpidem efficacy in the hippocampus of mice with the GABAA receptor gamma2 F77I point mutation

Manganese-enhanced magnetic resonance imaging reveals differential long-term neuroadaptation after methamphetamine and the substituted cathinone 4-methylmethcathinone (mephedrone).

Maturation of cultured hippocampal slices results in increased excitability in granule cells

Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse.

Methadone increases intracellular calcium in SH-SY5Y and SH-EP1-halpha7 cells by activating neuronal nicotinic acetylcholine receptors

Mitochondrial respiratory dysfunction due to the conversion of substituted cathinones to methylbenzamides in SH-SY5Y cells

Modifying the subunit composition of TASK channels alters the modulation of a leak conductance in cerebellar granule neurons.

Morphine-nicotine interaction in conditioned place preference in mice after chronic nicotine exposure

Multimetric statistical analysis of behavior in mice selected for high and low levels of isolation-induced male aggression.

Multiple actions of fenamates and other nonsteroidal anti-inflammatory drugs on GABAA receptors

Neurosteroid Agonist at GABAA receptor induces persistent neuroplasticity in VTA dopamine neurons

Neurotoxicity of Ammonia.

Normal extinction and reinstatement of morphine-induced conditioned place preference in the GluA1-KO mouse line

Paradoxical widespread c-Fos expression induced by a GABA agonist in the forebrain of transgenic mice with ectopic expression of the GABA(A) α6 subunit

Prototypic GABA(A) receptor agonist muscimol acts preferentially through forebrain high-affinity binding sites.

RFamide-related peptides signal through the neuropeptide FF receptor and regulate pain-related responses in the rat.

Reduced benzodiazepine tolerance, but increased flumazenil-precipitated withdrawal in AMPA-receptor GluR-A subunit-deficient mice

Regulation of GABA(A) receptor subunit expression by pharmacological agents.

Removal of GABA(A) receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations

Reversal of novelty-induced hippocampal c-Fos expression in GluA1 subunit-deficient mice by chronic treatment targeting glutamatergic transmission

Reversal of novelty-induced hyperlocomotion and hippocampal c-Fos expression in GluA1 knockout male mice by the mGluR2/3 agonist LY354740.

Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through αβγ2-type GABA(A) Receptors.

Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics

Selective increases of AMPA, NMDA, and kainate receptor subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics

Selective reduction of gamma-aminobutyric acid type A receptor delta subunit mRNA levels by MK-801 in rat dentate gyrus

Simo S. Oja--amino acids all along as building blocks of brain and life

TASK-3 knockout mice exhibit exaggerated nocturnal activity, impairments in cognitive functions, and reduced sensitivity to inhalation anesthetics

The alpha2-adrenoceptor antagonist atipamezole reduces the development and expression of d-amphetamine-induced behavioural sensitization

The impact of sub-cellular location and intracellular neuronal proteins on properties of GABA(A) receptors.

The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists.