Search filters

List of works by John D. Parker

Acetylcholine acutely modifies nitric oxide synthase function in the human coronary circulation.

scientific article published on 3 September 2010

Acute (but not chronic) smoking paradoxically protects the endothelium from ischemia and reperfusion: insight into the "smoking paradox".

scientific article

Acute and chronic effects of glyceryl trinitrate therapy on insulin and glucose regulation in humans

scientific article published on 10 December 2012

Acute effects of angiotensin-converting enzyme inhibition versus angiotensin II receptor blockade on cardiac sympathetic activity in patients with heart failure

scientific article

Acute heart failure in the elderly: differences in clinical characteristics, outcomes, and prognostic factors in the VERITAS Study

scientific article published on 5 January 2015

Adverse effects of atrioventricular synchronous right ventricular pacing on left ventricular sympathetic activity, efficiency, and hemodynamic status

scientific article published on 26 May 2006

Assessment of vascular function: flow-mediated constriction complements the information of flow-mediated dilatation

scientific article published on 26 October 2009

Avoidance of the left lateral decubitus position during sleep in patients with heart failure: relationship to cardiac size and function

scientific article published in January 2003

B-type natriuretic peptide in pregnant women with heart disease

scientific article published on 01 October 2010

Biochemical, hemodynamic, and vascular evidence concerning the free radical hypothesis of nitrate tolerance

scientific article published on 01 May 1999

Biventricular pacemaker upgrade in previously paced heart failure patients--improvements in ventricular dyssynchrony

scientific article published in April 2006

Biventricular pacing in patients with right ventricular pacing-induced heart failure

scientific article published on 01 December 2006

Cardiac and systemic sympathetic activity in response to clonidine in human heart failure

scientific article published on 01 January 1999

Cardiac resynchronization therapy after atrioventricular node ablation for rapid atrial fibrillation in a heart transplant recipient with late allograft dysfunction

scientific article published on 15 March 2010

Cardiac resynchronization therapy: an option for inotrope-supported patients with end-stage heart failure?

scientific article published in March 2005

Cardiac resynchronization therapy: retiming the failing right ventricle

scientific article published on 01 April 2005

Cardiac sympathetic activation in patients with pulmonary arterial hypertension

scientific article

Cardiac-specific sympathetic activation in men and women with and without heart failure

scientific article published on 28 September 2010

Chronic pharmacological preconditioning against ischemia.

scientific article published on January 2011

Chronic protection against ischemia and reperfusion-induced endothelial dysfunction during therapy with different organic nitrates

scientific article published in June 2012

Coadministration of atorvastatin prevents nitroglycerin-induced endothelial dysfunction and nitrate tolerance in healthy humans

scientific article published on 01 January 2011

Comparison of the effects of pentaerythritol tetranitrate and nitroglycerin on endothelium-dependent vasorelaxation in male volunteers

scientific article published in June 2003

Conduit artery constriction mediated by low flow a novel noninvasive method for the assessment of vascular function.

scientific article published in May 2008

Continuous therapy with transdermal nitroglycerin does not affect biomarkers of vascular inflammation and injury in healthy volunteers.

scientific article published in June 2009

Contrast nephropathy post cardiac resynchronization therapy: an under-recognized complication with important morbidity.

scientific article

Cost-effectiveness of 64-slice CT angiography compared to conventional coronary angiography based on a coverage with evidence development study in Ontario

scientific article published in October 2013

Counterregulatory responses: sustained-release isosorbide-5-mononitrate versus transdermal nitroglycerin

scientific article published on 01 November 1996

Daily ischemic preconditioning provides sustained protection from ischemia-reperfusion induced endothelial dysfunction: a human study.

scientific article published on 22 February 2013

Deployment of left ventricular lead from the ipsilateral side of central vein obstruction

scientific article published in June 2005

Differential effects of pentaerythritol tetranitrate and nitroglycerin on the development of tolerance and evidence of lipid peroxidation: a human in vivo study

scientific article published in September 2001

Digoxin reduces cardiac sympathetic activity in severe congestive heart failure

scientific article published on 01 July 1996

Eccentric dosing with isosorbide-5-mononitrate in angina pectoris.

scientific article

Effect of diuretic therapy on exercise capacity in patients with chronic angina and preserved left ventricular function

scientific article published on 01 May 2007

Effect of folic acid on nitrate tolerance in healthy volunteers: differences between arterial and venous circulation

scientific article

Effects of nitroglycerin treatment on baroreflex sensitivity and short-term heart rate variability in humans

scientific article published on 01 December 2002

Effects of percutaneous mitral valvuloplasty on left ventricular mass and volume

scientific article published on 01 October 1991

Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials

scientific article

Effects of therapy with nifedipine GITS or atenolol on mental stress-induced ischemic left ventricular dysfunction

scientific article published in November 1998

Efficacy and safety of sildenafil citrate in men with erectile dysfunction and chronic heart failure

scientific article published in January 2005

Endothelial function and hemorheological parameters modulate coronary blood flow in patients without significant coronary artery disease

scientific article published in January 2012

Endothelial function assessment: flow-mediated dilation and constriction provide different and complementary information on the presence of coronary artery disease

scientific article published on 14 September 2011

Estimation of mitral valve area from regression analysis of the pressure gradient in mitral stenosis

scientific article published on April 15, 1992

Evaluation of a novel sutureless anastomotic connector: from endothelial function to mid-term clinical and angiographic follow-up.

scientific article published in November 2003

Evidence of a weak correlation between peripheral endothelial function measures and carotid intima-media thickness

scientific article published on 01 January 2012

Evidence supporting abnormalities in nitric oxide synthase function induced by nitroglycerin in humans

scientific article

Fibrinogen synthesis is increased in cachectic patients with chronic heart failure

scientific article published on 19 November 2007

Flow-mediated constriction: further insight into a new measure of vascular function

scientific article published on 17 December 2010

Folic Acid does not limit endothelial dysfunction induced by ischemia and reperfusion: a human study

scientific article

Genetic variants are not associated with outcome in patients with coronary artery disease and left ventricular dysfunction: results of the Genetic Substudy of the Surgical Treatment for Ischemic Heart Failure (STICH) trials

scientific article

Haemodynamic and structural correlates of the first and second heart sounds in pulmonary arterial hypertension: an acoustic cardiography cohort study

scientific article published on 8 April 2013

Hemodynamic and biochemical effects of 100% oxygen breathing in humans

scientific article published on 01 February 1999

Hemodynamic and neurochemical determinates of renal function in chronic heart failure

scientific article

Identification of lateral cardiac veins for cardiac resynchronization therapy

scientific article published on 01 July 2006

Impaired baroreceptor control of renal sympathetic activity in human chronic heart failure

scientific article

Increased extraction of endothelin-1 across the failing human heart

scientific article published on 01 July 2001

Increased ventricular repolarization heterogeneity in patients with ventricular arrhythmia vulnerability and cardiomyopathy: a human in vivo study

scientific article published on 19 August 2005

Influence of obstructive sleep apnea on mortality in patients with heart failure

scientific article

Inhibition of sPLA2 and endothelial function: a substudy of the SPIDER-PCI trial

scientific article published on 26 January 2012

L-arginine transport in the human coronary and peripheral circulation

scientific article published on 8 March 2004

Lack of evidence for peripheral alpha(1)- adrenoceptor blockade during long-term treatment of heart failure with carvedilol

scientific article published in November 2001

Left ventricular strain patterns in dilated cardiomyopathy predict response to cardiac resynchronization therapy: timing is not everything

scientific article published on 24 January 2009

Left ventricular structural adaptations to obstructive sleep apnea in dilated cardiomyopathy

scientific article

Long-term endothelial dysfunction after coronary artery stenting

scientific article published on 01 November 1999

Long-term therapy with organic nitrates: the pros and cons of nitric oxide replacement therapy

scientific article published in August 2004

Loss of the preconditioning effect of rosuvastatin during sustained therapy: a human in vivo study

scientific article published on 14 October 2011

Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Stud

scientific article

Navigating the crossroads of coronary artery disease and heart failure.

scientific article published on September 2006

Nitrate-induced toxicity and preconditioning: a rationale for reconsidering the use of these drugs.

scientific article published on July 2008

Nitroglycerin attenuates human endothelial progenitor cell differentiation, function, and survival.

scientific article

Nitroglycerin protects the endothelium from ischaemia and reperfusion: human mechanistic insight.

scientific article published on 23 February 2007

Nitroglycerin withdrawal increases endothelium-dependent vasomotor response to acetylcholine.

scientific article

Observations of time-based measures of flow-mediated dilation of forearm conduit arteries: implications for the accurate assessment of endothelial function.

scientific article published on 16 July 2010

Once daily therapy with isosorbide-5-mononitrate causes endothelial dysfunction in humans: evidence of a free-radical-mediated mechanism

scientific article published on 12 March 2007

Ontario multidetector computed tomographic coronary angiography study: field evaluation of diagnostic accuracy

scientific article published on 14 March 2011

Parameters of blood viscosity do not correlate with the extent of coronary and carotid atherosclerosis and with endothelial function in patients undergoing coronary angiography

scientific article published in January 2012

Peak oxygen uptake is not determined by cardiac noradrenaline spillover in heart failure

scientific article

Pentaerythrityl tetranitrate and nitroglycerin, but not isosorbide mononitrate, prevent endothelial dysfunction induced by ischemia and reperfusion

scientific article published on 19 July 2007

Peripheral hemorheological and vascular correlates of coronary blood flow

scientific article published on January 1, 2011

Platelet cyclic GMP responses to nitroglycerin

scientific article published on 01 August 2000

Postconditioning fails to prevent radial artery endothelial dysfunction induced by ischemia and reperfusion: evidence from a human in vivo study

scientific article published on 01 June 2006

Predictive value of local and core laboratory echocardiographic assessment of cardiac function in patients with chronic stable angina: The ACTION study

scientific article published on 06 April 2007

Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS.

scientific article published on 22 December 2015

Prevalence and physiological predictors of sleep apnea in patients with heart failure and systolic dysfunction.

scientific article published on 21 January 2009

Relation of periodic leg movements during sleep and mortality in patients with systolic heart failure

scientific article

Relationship between sleep apnoea and mortality in patients with ischaemic heart failure

scientific article published on 8 January 2009

Relationship of carbon dioxide tension in arterial blood to pulmonary wedge pressure in heart failure

scientific article published in January 2002

Relationship of systolic BP to obstructive sleep apnea in patients with heart failure

scientific article published in May 2003

Renal handling of endothelin in patients with chronic heart failure

scientific article published on 01 February 2005

Repeated daily dosing with sildenafil provides sustained protection from endothelial dysfunction caused by ischemia and reperfusion: a human in vivo study.

scientific article

Rosiglitazone causes endothelial dysfunction in humans

scientific article published on 03 November 2011

Rosuvastatin prevents conduit artery endothelial dysfunction induced by ischemia and reperfusion by a cyclooxygenase-2-dependent mechanism.

scientific article published in March 2010

Safety of intravenous nitroglycerin after administration of sildenafil citrate to men with coronary artery disease: a double-blind, placebo-controlled, randomized, crossover trial

scientific article published on 01 August 2007

Selective versus nonselective beta-adrenergic receptor blockade in chronic heart failure: differential effects on myocardial energy substrate utilization

scientific article published in June 2005

Serial assessment of left ventricular function and mass after orthotopic heart transplantation: a 4-year longitudinal study

scientific article published on 01 January 1992

Sildenafil prevents endothelial dysfunction induced by ischemia and reperfusion via opening of adenosine triphosphate-sensitive potassium channels: a human in vivo study

scientific article published on 7 February 2005

Sleepiness and sleep in patients with both systolic heart failure and obstructive sleep apnea

scientific article published in September 2006

Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe?

scientific article published on 4 September 2017

Tezosentan in patients with acute heart failure: design of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Study (VERITAS).

scientific article published in July 2005

The angiotensin II-receptor antagonist losartan does not prevent hemodynamic or vascular tolerance to nitroglycerin

scientific article published on 01 November 1999

The effects of dobutamine on cardiac sympathetic activity in patients with congestive heart failure

scientific article published in April 2002

The effects of dobutamine on renal sympathetic activity in human heart failure

scientific article published in May 2008

The effects of intravenous sildenafil on hemodynamics and cardiac sympathetic activity in chronic human heart failure

scientific article published on 10 July 2006

The endothelial-protective effects of HMG-CoA reductase inhibition in the setting of ischemia and reperfusion injury.

scientific article published on January 2010

The impact of rosiglitazone on nitric oxide bioavailability and endothelial function

scientific article published on January 1, 2010

The puzzle of nitrate tolerance: pieces smaller than we thought?

scientific article

Therapeutic developments in the therapy of heart failure: lessons to be learned

scientific article published on 17 June 2015

Therapy with nitrates: increasing evidence of vascular toxicity

scientific article published on 01 November 2003

Tolerance to nitroglycerin-induced preconditioning of the endothelium: a human in vivo study

scientific article published on 20 November 2009

Use of skin conductance changes during mental stress testing as an index of autonomic arousal in cardiovascular research

scientific article

Vagal heart rate responses to chronic beta-blockade in human heart failure relate to cardiac norepinephrine spillover

scientific article published in August 2005

Worsening heart failure, a critical event during hospital admission for acute heart failure: results from the VERITAS study

article

β-blockade restores muscle sympathetic rhythmicity in human heart failure

scientific article published on 26 April 2011

“Dose-dependent” Impact of Recurrent Cardiac Events on Mortality in Patients with Heart Failure

article