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List of works by Delphine Borgel

A Comparative Study of the Protein C Pathway in Septic and Nonseptic Patients with Organ Failure

scientific article published on 02 August 2007

A capillary zone electrophoresis method to detect conformers and dimers of antithrombin in therapeutic preparations

scientific article published on 05 April 2016

A chemically-modified inactive antithrombin as a potent antagonist of fondaparinux and heparin anticoagulant activity.

scientific article published in June 2013

A fast capillary electrophoresis method to assess the binding affinity of recombinant antithrombin toward heparin directly from cell culture supernatants.

scientific article

A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation

scientific article published in December 2017

A mutation in the gene coding for the sialic acid transporter SLC35A1 is required for platelet life span but not proplatelet formation

article

Acquired protein S deficiency leads to obliterative portal venopathy and to compensatory nodular regenerative hyperplasia in HIV-infected patients

article

Activated protein C, a protein at the crossroads between coagulation and inflammation

scientific article published on 25 May 2011

An ADAM-10 dependent EPCR shedding links meningococcal interaction with endothelial cells to purpura fulminans.

scientific article published on 9 April 2018

Antithrombin is not protective against renal ischaemia-reperfusion injury

scientific article published on 27 October 2016

Assessment of the interplay between blood and skin vascular abnormalities in adult purpura fulminans

scientific article

Characterization of cleaved plasma protein S with a monoclonal antibody-based assay

scientific article published on 01 October 2000

Characterization of conformers and dimers of antithrombin by capillary electrophoresis-quadrupole-time-of-flight mass spectrometry

scientific article published on 14 October 2016

Characterization of the Annonaceous acetogenin, annonacinone, a natural product inhibitor of plasminogen activator inhibitor-1.

scientific article published on 23 November 2016

Cleaved protein S (PS), total PS, free PS, and activated protein C cofactor activity as risk factors for venous thromboembolism

scientific article published on 01 April 2003

Clinical variability and probable founder effect in oculocutaneous albinism type 7

scientific article published on 06 November 2019

Clinical, laboratory and molecular findings and long-term follow-up data in 96 French patients with PMM2-CDG (phosphomannomutase 2-congenital disorder of glycosylation) and review of the literature.

scientific article published on 27 September 2017

Coagulation phenotypes in septic shock as evaluated by calibrated automated thrombography

scientific article published on January 2015

Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions

scientific article published on 17 February 2017

Connexin 37 limits thrombus propensity by downregulating platelet reactivity.

scientific article published in August 2011

Decreased ADAMTS-13 (A disintegrin-like and metalloprotease with thrombospondin type 1 repeats) is associated with a poor prognosis in sepsis-induced organ failure*

scientific article published on 01 October 2007

Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A-4

scientific article published on 26 July 2018

Development of a novel immunoassay for the assessment of plasma Gas6 concentrations and their variation with hormonal status.

scientific article published on 23 August 2007

Development of a recombinant antithrombin variant as a potent antidote to fondaparinux and other heparin derivatives

article

Elevated growth-arrest-specific protein 6 plasma levels in patients with severe sepsis

scientific article published on 01 January 2006

Elevated thrombin generation in patients with congenital disorder of glycosylation and combined coagulation factor deficiencies

scientific article published on 28 July 2019

Endothelial cell surface limits coagulation without modulating the antithrombin potency

scientific article published on 17 May 2018

Expression and characterization of recombinant protein S with the Ser 460 Pro mutation.

scientific article

Familial thrombophilia is an oligogenetic disease: involvement of the prothrombin G20210A, PROC and PROS gene mutations

scientific article published on 01 February 2003

First case of sporadic protein S deficiency due to a novel candidate mutation, Ala 484-->Pro, in the protein S active gene (PROS1)

article

First frameshift mutation in the active protein S gene associated with a quantitative hereditary deficiency

scientific article published in August 1994

Fulminant arterial vasculitis as an unusual complication of disseminated staphylococcal disease due to the emerging CC1 methicillin-susceptible Staphylococcus aureus clone: a case report

scientific article published on 03 April 2019

Functional properties of the sex-hormone-binding globulin (SHBG)-like domain of the anticoagulant protein S.

scientific article

Gas6 inflames cell interactions

scientific article published on 01 April 2008

Gross deletions/duplications in PROS1 are relatively common in point mutation-negative hereditary protein S deficiency.

scientific article published on 23 May 2009

Growth-arrest-specific 6 (GAS6) protein in ARDS patients: determination of plasma levels and influence of PEEP setting

scientific article published on 9 April 2013

Identification of 15 different candidate causal point mutations and three polymorphisms in 19 patients with protein S deficiency using a scanning method for the analysis of the protein S active gene

article

Impact of heparin or non-heparin coated circuits on platelet function in pediatric cardiac surgery

scientific article published on 03 November 2018

Inactivated antithombin as anticoagulant reversal in a rat model of cardiopulmonary bypass: a potent and potentially safer alternative to protamine.

scientific article

Inactivated antithrombins as fondaparinux antidotes: a promising alternative to haemostatic agents as assessed in vitro in a thrombin-generation assay.

scientific article published on 14 July 2016

Increased secretion of Gas6 by smooth muscle cells in human atherosclerotic carotid plaques

scientific article published on 10 November 2011

Inefficacy of ultrasound-guided local injections of autologous conditioned plasma for recent epicondylitis: results of a double-blind placebo-controlled randomized clinical trial with one-year follow-up.

scientific article

Infections et inflammations

Inflammation in deep vein thrombosis: a therapeutic target?

scientific article published on 01 December 2019

Influence of PROS1 gene mutations affecting protein S amino-acid 275 on plasma free protein S measurement

scientific article published in April 2007

International clinical guidelines for the management of phosphomannomutase 2-congenital disorders of glycosylation: Diagnosis, treatment and follow up

scientific article published on 01 January 2019

Kinesin-1 Is a New Actor Involved in Platelet Secretion and Thrombus Stability.

scientific article published on 8 March 2018

Long-term follow-up in PMM2-CDG: are we ready to start treatment trials?

scientific article published on 08 October 2018

Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6.

scientific article published on 20 November 2009

Measuring beta-galactose exposure on platelets: Standardization and healthy reference values

scientific article published on 02 June 2020

Molecular bases of type II protein S deficiency: the I203-D204 deletion in the EGF4 domain alters GLA domain function

scientific article published on 01 January 2006

Molecular basis for protein S hereditary deficiency: Genetic defects observed in 118 patients with type I and type IIa deficiencies1

scientific article published on 01 August 1996

Novel human pathological mutations. Gene symbol: PROS1. Disease: Protein S deficiency

article

Pathogenesis of meningococcal purpura fulminans.

scientific article published on 9 March 2017

Pharmacokinetics of Enoxaparin After Renal Transplantation in Pediatric Patients

scientific article published on 26 September 2018

Physiological Plasma Gas6 Levels Do Not Influence Platelet Aggregation

scientific article published on 01 March 2006

Plasma levels of the growth arrest-specific gene 6 product (Gas6) and antiplatelet drug responsiveness in healthy subjects

scientific article (publication date: October 2006)

Platelet-mapping assay for monitoring antiplatelet therapy during mechanical circulatory support in children: A retrospective observational study

scientific article published on 20 June 2017

Preanalytical influence of pneumatic tube delivery system on results of routine biochemistry and haematology analysis

scientific article published on 18 October 2017

Protein C and protein S deficiencies.

scientific article

Protein S deficiency

scientific article published on 01 July 1997

Protein S deficiency: a database of mutations. For the Plasma Coagulation Inhibitors Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis

scholarly article by S Gandrille et al published June 1997 in Thrombosis and Haemostasis

Protein S deficiency: different biological phenotypes according to the assays used

scientific article published on 01 February 1998

Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease: preclinical and clinical evidence

scientific article published on 28 February 2019

Sepsis and coagulation

scientific article published on 01 October 2005

TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology

scientific article published on 01 December 2018

Targeting VEGFR1 on endothelial progenitors modulates their differentiation potential.

scientific article published on 14 January 2014

The -33T-->C polymorphism in intron 7 of the TFPI gene influences the risk of venous thromboembolism, independently of the factor V Leiden and prothrombin mutations

article

The Ser 460 to Pro substitution of the protein S alpha (PROS1) gene is a frequent mutation associated with free protein S (type IIa) deficiency

article

The gamma-carboxyglutamic acid domain of anticoagulant protein S is involved in activated protein C cofactor activity, independently of phospholipid binding.

scientific article published on 12 August 2004

The protein S thrombin-sensitive region modulates phospholipid binding and the gamma-carboxyglutamic acid-rich (Gla) domain conformation in a non-specific manner

scientific article published on 01 March 2006

Three-dimensional model of the SHBG-like region of anticoagulant protein S: new structure-function insights

scientific article

Thrombomodulin favors leukocyte microvesicle fibrinolytic activity, reduces NETosis and prevents septic shock-induced coagulopathy in rats.

scientific article published on 8 December 2017

Trends in the development of oral anticoagulants

scientific article

Unbalance between plasma levels of Protein Z and protein Z-dependent inhibitor in patients with colorectal and pancreatic cancer: a pilot study.

scientific article

Vascular endothelial growth factor, as compared with placental growth factor, is increased in severe sepsis but not in organ failure

scientific article published on 01 May 2012

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