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List of works by Hannu Koistinen

A sensitive proximity ligation assay for active PSA

scientific article published on 01 June 2006

Absence of TGF-β Receptor Activation by Highly Purified hCG Preparations.

scientific article

Altered glycosylation of glycodelin in endometrial carcinoma

scientific article published on 23 March 2020

Antiangiogenic properties of prostate-specific antigen (PSA).

scientific article published on January 2009

Anticancer activity of the protein kinase C modulator HMI-1a3 in 2D and 3D cell culture models of androgen-responsive and androgen-unresponsive prostate cancer.

scientific article

Collagen degradation by tumor-associated trypsins.

scientific article published on 28 March 2013

Collagen formation and degradation increase during growth hormone therapy in children

scientific article published on 01 February 1997

DNA damage recognition via activated ATM and p53 pathway in nonproliferating human prostate tissue

scientific article published on 26 October 2010

Development of molecules stimulating the activity of KLK3 - an update.

scientific article

Development of peptides specifically modulating the activity of KLK2 and KLK3.

scientific article published on June 2008

Direct pathway cloning and expression of the radiosumin biosynthetic gene cluster

scientific article published in 2023

Discovery of varlaxins, new aeruginosin-type inhibitors of human trypsins ⬇️

scientific article published on 9 March 2022

Effects of differential glycosylation of glycodelins on lymphocyte survival

scientific article

Elevated levels of amyloid precursor protein in muscle of patients with amyotrophic lateral sclerosis and a mouse model of the disease

scientific article published on 01 October 2006

Emerging Roles of SPINK1 in Cancer.

scientific article

Evaluation of peptides as protease inhibitors and stimulators.

scientific article published in January 2014

Gene expression changes associated with the anti-angiogenic activity of kallikrein-related peptidase 3 (KLK3) on human umbilical vein endothelial cells

scientific article published on 01 June 2008

Glycodelin expression associates with differential tumour phenotype and outcome in sporadic and familial non-BRCA1/2 breast cancer patients

article published in 2010

Glycodelin reduces breast cancer xenograft growth in vivo.

scientific article

Glycodelin-A as a paracrine regulator in early pregnancy

scientific article published on 08 June 2011

Glycodelin-A interacts with fucosyltransferase on human sperm plasma membrane to inhibit spermatozoa-zona pellucida binding

scientific article

Glycodelin-A modulates syncytialization of human BeWo choriocarcinoma cell line.

scientific article

Glycodelin-A stimulates the conversion of human peripheral blood CD16-CD56bright NK cell to a decidual NK cell-like phenotype

scientific article published on 01 April 2019

Glycodelin-A treatment reduces the adverse effect of macrophage co-culture on human sperm motility

scientific article published on 09 May 2014

Glycodelin: a reproduction-related lipocalin

scientific article (publication date: 18 October 2000)

Human chorionic gonadotropin and its free β-subunit stimulate trophoblast invasion independent of LH/hCG receptor.

scientific article published on 17 May 2013

Hyperglycosylated hCG activates LH/hCG-receptor with lower activity than hCG

scientific article published on 02 October 2018

Insulin-like growth factor I is not a useful marker of prostate cancer in men with elevated levels of prostate-specific antigen

scientific article published on 01 August 2000

Interleukin-6 increases expression of serine protease inhibitor Kazal type 1 through STAT3 in colorectal adenocarcinoma

scientific article published on 14 December 2015

KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D.

scientific article published on 17 May 2019

MAPK inhibitors induce serine peptidase inhibitor Kazal type 1 (SPINK1) secretion in BRAF V600E-mutant colorectal adenocarcinoma.

scientific article published on 28 November 2017

Mimetics of the disulfide bridge between the N- and C-terminal cysteines of the KLK3-stimulating peptide B-2.

scientific article published on 5 December 2009

Novel peptide inhibitors of human kallikrein 2.

scientific article

Novel small molecule inhibitors for prostate-specific antigen

scientific article

PSA forms complexes with α1-antichymotrypsin in prostate.

scientific article

Peptides binding to prostate-specific antigen enhance its antiangiogenic activity

scientific article published on 16 March 2012

Potent Inhibitor of Human Trypsins from the Aeruginosin Family of Natural Products

scientific article

Prostate Cancer Risk-Associated Single-Nucleotide Polymorphism Affects Prostate-Specific Antigen Glycosylation and Its Function

scientific article published on 11 December 2018

Proteolytic activity of prostate-specific antigen (PSA) towards protein substrates and effect of peptides stimulating PSA activity

scientific article

Proximity ligation measurement of the complex between prostate specific antigen and alpha1-protease inhibitor

scientific article published on 30 July 2009

Pseudopeptides with a centrally positioned alkene-based disulphide bridge mimetic stimulate kallikrein-related peptidase 3 activity

scholarly article by Kristian Meinander et al published 2013 in MedChemComm

Relaxin stimulates glycodelin mRNA and protein concentrations in human endometrial glandular epithelial cells

scientific article published on 01 April 1999

Replacement of the Disulfide Bridge in a KLK3-Stimulating Peptide Using Orthogonally Protected Building Blocks.

scientific article published on 16 December 2013

Repressed PKCδ activation in glycodelin-expressing cells mediates resistance to phorbol ester and TGFβ.

scientific article published on 29 June 2016

Specificity profiling of human trypsin-isoenzymes

scientific article published on 01 September 2018

Structural characterization and anti-angiogenic properties of prostate-specific antigen isoforms in seminal fluid.

scientific article

The Pleiotropic Effect of Glycodelin-A in Early Pregnancy.

scientific article

The effect of exercise on leptin concentration in healthy men and in type 1 diabetic patients

scientific article published in June 1998

Trypsin-2 enhances carcinoma invasion by processing tight junctions and activating ProMT1-MMP.

scientific article

Virtual Screening of Small Drug-Like Compounds Stimulating the Enzymatic Activity of Kallikrein-Related Peptidase 3 (KLK3).

scientific article

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