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List of works by Susan J. Gunst

A novel role for RhoA GTPase in the regulation of airway smooth muscle contraction

scientific article

Actin cytoskeletal dynamics in smooth muscle: a new paradigm for the regulation of smooth muscle contraction.

scientific article published on 2 July 2008

Actin depolymerization factor/cofilin activation regulates actin polymerization and tension development in canine tracheal smooth muscle

scientific article published on 27 October 2008

Actin polymerization stimulated by contractile activation regulates force development in canine tracheal smooth muscle

article

Actions by actin: reciprocal regulation of cortactin activity by tyrosine kinases and F-actin.

scientific article published on June 2004

Activation of the Arp2/3 complex by N-WASp is required for actin polymerization and contraction in smooth muscle

scientific article published on 29 December 2004

Activation of vinculin induced by cholinergic stimulation regulates contraction of tracheal smooth muscle tissue.

scientific article

Altered calcium signaling in colonic smooth muscle of type 1 diabetic mice

scientific article

Analysis of receptor reserves in canine tracheal smooth muscle

scientific article published on 01 April 1987

Applicability of the sliding filament/crossbridge paradigm to smooth muscle.

scientific article

Bronchoprotective and bronchodilatory effects of deep inspiration in rabbits subjected to bronchial challenge

scientific article published in December 2001

Ca2+ sensitivity of contractile activation during muscarinic stimulation of tracheal muscle

scientific article published on 01 December 1992

Chronic continuous positive airway pressure (CPAP) reduces airway reactivity in vivo in an allergen-induced rabbit model of asthma.

scientific article

Chronic inflation of ferret lungs with CPAP reduces airway smooth muscle contractility in vivo and in vitro

scientific article

Chronic strain alters the passive and contractile properties of rabbit airways

scientific article published on 27 January 2005

Comparison of elastic properties and contractile responses of isolated airway segments from mature and immature rabbits

scientific article

Comparison of the shear modulus of mature and immature rabbit lungs.

scientific article

Computational model of airway narrowing: mature vs. immature rabbit

scientific article

Contractile force and intracellular Ca2+ during relaxation of canine tracheal smooth muscle

scientific article

Contractile force of canine airway smooth muscle during cyclical length changes

scientific article published on 01 September 1983

Contractile force of canine tracheal smooth muscle during continuous stretch

scientific article published on 01 March 1982

Contraction history modulates isotonic shortening velocity in smooth muscle

scientific article published on 01 August 1993

Cytoskeletal remodeling in differentiated vascular smooth muscle is actin isoform dependent and stimulus dependent

scientific article published on 2 July 2008

Cytoskeletal remodeling of the airway smooth muscle cell: a mechanism for adaptation to mechanical forces in the lung.

scientific article published on September 2003

Depletion of focal adhesion kinase by antisense depresses contractile activation of smooth muscle

scientific article published in April 2001

Differences in Ca2+ mobilization by muscarinic agonists in tracheal smooth muscle

scientific article published on 01 January 1993

Differences in airway structure in immature and mature rabbits

scientific article published on 01 October 2000

Does airway inflation stretch the bronchial mucosal membrane?

scientific article published in December 2005

Dynamic association between alpha-actinin and beta-integrin regulates contraction of canine tracheal smooth muscle

scientific article published in May 2006

Effect of CPAP on airway reactivity and airway inflammation in children with moderate-severe asthma

scientific article published on 16 November 2018

Effect of Na-K adenosinetriphosphatase activity on relaxation of canine tracheal smooth muscle

scientific article published on 01 February 1988

Effect of inflation on trachealis muscle tone in canine tracheal segments in vitro

scientific article published on 01 April 1983

Effect of tidal volume and frequency on airway responsiveness in mechanically ventilated rabbits

scientific article published on 01 October 1997

Effect of transpulmonary pressure on airway diameter and responsiveness of immature and mature rabbits

scientific article published on 01 October 2000

Effects of muscle length and load on intracellular Ca2+ in tracheal smooth muscle

scientific article published on 01 April 1989

Effects of muscle length on intracellular Ca2+ during isometric contraction of tracheal smooth muscle

scientific article published on 01 January 1991

Elastase Alters Contractility and Promotes an Inflammatory Synthetic Phenotype in Airway Smooth Muscle Tissues

scientific article published on 6 December 2017

Expression of non-phosphorylatable paxillin mutants in canine tracheal smooth muscle inhibits tension development

scientific article

Focal adhesion kinase (FAK) and mechanical stimulation negatively regulate the transition of airway smooth muscle tissues to a synthetic phenotype

scientific article published on 9 September 2016

Greater airway narrowing in immature than in mature rabbits during methacholine challenge

scientific article published on 01 December 1996

Halothane alters the response of isolated airway smooth muscle to carbon dioxide

scientific article published in February 1992

Halothane, enflurane, and isoflurane depress the peripheral vagal motor pathway in isolated canine tracheal smooth muscle

scientific article published in February 1991

Histamine tachyphylaxis in canine airways despite prostaglandin synthesis inhibition

scientific article published in November 1988

Increased mechanical strain imposed on murine lungs during ventilation in vivo depresses airway responsiveness and activation of protein kinase Akt

scientific article published on 14 March 2013

Inhibition of p21 activated kinase (PAK) reduces airway responsiveness in vivo and in vitro in murine and human airways

scientific article

Integrin-linked kinase regulates N-WASp-mediated actin polymerization and tension development in tracheal smooth muscle

scientific article published on 25 September 2007

Integrin-linked kinase regulates smooth muscle differentiation marker gene expression in airway tissue.

scientific article published on 19 September 2008

Interaction of contractile responses in canine tracheal smooth muscle

scientific article published on 01 August 1987

Interactions of airway smooth muscle cells with their tissue matrix: implications for contraction

scientific article published on January 2008

Last Word on Point: Alterations in airway smooth muscle phenotype do cause airway hyperresponsiveness in asthma.

scientific article

Limitation of maximal bronchoconstriction in living dogs

scientific article published in March 1992

Maximal airway response in mature and immature rabbits during tidal ventilation.

scientific article

Mechanical properties of contracted canine bronchial segments in vitro

scientific article published on 01 June 1981

Mechanical stimuli and IL-13 interact at integrin adhesion complexes to regulate expression of smooth muscle myosin heavy chain in airway smooth muscle tissue

scientific article

Mechanisms for the mechanical plasticity of tracheal smooth muscle

scientific article published on 01 May 1995

Mechanisms for the mechanical response of airway smooth muscle to length oscillation

scientific article published on 01 September 1997

Mechanosensitive tyrosine phosphorylation of paxillin and focal adhesion kinase in tracheal smooth muscle

scientific article published on 01 January 1999

Molecular Mechanisms for the Mechanical Modulation of Airway Responsiveness

scientific article published on 19 February 2019

Muscarinic receptor reserve and beta-adrenergic sensitivity in tracheal smooth muscle.

scientific article

Non-muscle (NM) myosin heavy chain phosphorylation regulates the formation of NM myosin filaments, adhesome assembly and smooth muscle contraction

scientific article

On the terminology for describing the length-force relationship and its changes in airway smooth muscle

scientific article published in December 2004

Parenchymal interdependence and airway response to methacholine in excised dog lobes

scientific article published in December 1988

Pharmacological modulation of the mechanical response of airway smooth muscle to length oscillation

scientific article published on 01 September 1997

Phenotype transitions induced by mechanical stimuli in airway smooth muscle are regulated by differential interactions of parvin isoforms with paxillin and Akt

scientific article published on 04 March 2020

Phosphorylation of dense-plaque proteins talin and paxillin during tracheal smooth muscle contraction

scientific article published on 01 March 1995

Physiology, reductionism, and translational medicine: the right mix

scientific article published on 19 August 2011

Point: alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma

scientific article

Pressure-volume and length-stress relationships in canine bronchi in vitro ⬇️

article by S J Gunst & J Q Stropp published June 1988 in Journal of Applied Physiology

Regulation of 130-kDa smooth muscle myosin light chain kinase expression by an intronic CArG element.

scientific article published on 22 October 2013

Regulation of isotonic shortening velocity by second messengers in tracheal smooth muscle

scientific article published on 01 March 1994

Relationship between paxillin and myosin phosphorylation during muscarinic stimulation of smooth muscle

scientific article published on 01 March 1998

Respiratory system responsiveness in rabbits in vivo is reduced by prolonged continuous positive airway pressure

scientific article published on 7 April 2005

Rho Kinase (ROCK) collaborates with Pak to Regulate Actin Polymerization and Contraction in Airway Smooth Muscle.

scientific article

Role of contractile protein activation in the length-dependent modulation of tracheal smooth muscle force

scientific article published on 01 January 1996

Role of protein kinase Calpha in regulation of [Ca2+](I) and force in human myometrium

scientific article published on 15 December 2008

S100A4 is activated by RhoA and catalyzes the polymerization of non-muscle myosin, adhesion complex assembly and contraction in airway smooth muscle

scientific article published on 07 August 2020

S100A4 is secreted by airway smooth muscle tissues and activates inflammatory signaling pathways via Receptors for Advanced Glycation End products (RAGE)

scientific article published on 20 May 2020

Selected contribution: plasticity of airway smooth muscle stiffness and extensibility: role of length-adaptive mechanisms

scientific article published on 01 February 2001

Selected contribution: roles of focal adhesion kinase and paxillin in the mechanosensitive regulation of myosin phosphorylation in smooth muscle

scientific article

Silencing of p21-activated kinase attenuates vimentin phosphorylation on Ser-56 and reorientation of the vimentin network during stimulation of smooth muscle cells by 5-hydroxytryptamine.

scientific article published on June 2005

Tension development during contractile stimulation of smooth muscle requires recruitment of paxillin and vinculin to the membrane

scientific article published on 22 October 2003

Th17 cells contribute to pulmonary fibrosis and inflammation during chronic kidney disease progression following acute ischemia

scientific article

The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle

scientific article

The contractile apparatus and mechanical properties of airway smooth muscle.

scientific article

The effects of the small GTPase RhoA on the muscarinic contraction of airway smooth muscle result from its role in regulating actin polymerization.

scientific article

The first three minutes: smooth muscle contraction, cytoskeletal events, and soft glasses.

scientific article

The focal adhesion protein paxillin regulates contraction in canine tracheal smooth muscle

scientific article

The small GTPase Cdc42 regulates actin polymerization and tension development during contractile stimulation of smooth muscle

scientific article published on 27 September 2004

The small GTPase RhoA regulates the contraction of smooth muscle tissues by catalyzing the assembly of cytoskeletal signaling complexes at membrane adhesion sites

scientific article

Type V collagen-induced tolerance prevents airway hyperresponsiveness.

scientific article published in February 2013

Use of continuous positive airway pressure reduces airway reactivity in adults with asthma

scientific article published on 26 July 2012

Vasodilator-stimulated phosphoprotein (VASP) regulates actin polymerization and contraction in airway smooth muscle by a vinculin-dependent mechanism

scientific article published on 10 March 2015

Vinculin phosphorylation at Tyr1065 regulates vinculin conformation and tension development in airway smooth muscle tissues

scientific article published on 13 December 2013

p21-Activated kinase (Pak) regulates airway smooth muscle contraction by regulating paxillin complexes that mediate actin polymerization

scientific article published on 29 May 2016

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