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List of works by Fabio Arnesano

A docking approach to the study of copper trafficking proteins; interaction between metallochaperones and soluble domains of copper ATPases.

scientific article published in April 2004

A redox switch in CopC: An intriguing copper trafficking protein that binds copper(I) and copper(II) at different sites

scientific article (publication date: April 2003)

A strategy for the NMR characterization of type II copper(II) proteins: the case of the copper trafficking protein CopC from Pseudomonas Syringae

scientific article

Activation of Platinum(IV) Prodrugs by Cytochrome c and Characterization of the Protein Binding Sites.

scientific article published on 9 August 2016

Aggregation pathways of native-like ubiquitin promoted by single-point mutation, metal ion concentration and dielectric constant of the medium.

scientific article published on 20 December 2017

Amyloid transition of ubiquitin on silver nanoparticles produced by pulsed laser ablation in liquid as a function of stabilizer and single-point mutations.

scientific article

An Italian contribution to structural genomics: Understanding metalloproteins

article

C60@Lysozyme: direct observation by nuclear magnetic resonance of a 1:1 fullerene protein adduct

scientific article

Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs

scientific article published on 27 May 2015

Chemical and cellular investigations of trans-ammine-pyridine-dichlorido-platinum(II), the likely metabolite of the antitumor active cis-diammine-pyridine-chorido-platinum(II).

scientific article published on 14 August 2013

Cisplatin handover between copper transporters: the effect of reducing agents

scientific article published on 01 May 2014

Cisplatin reacts with histone H1 and the adduct forms a ternary complex with DNA

scientific article published on 01 March 2019

Computational metallomics of the anticancer drug cisplatin

scientific article

Concentration-dependent effects of mercury and lead on Aβ42: possible implications for Alzheimer's disease

scientific article published on 02 January 2019

Conformational selection of ubiquitin quaternary structures driven by zinc ions

scientific article published on 10 October 2013

Copper binding to naturally occurring, lactam form of angiogenin differs from that to recombinant protein, affecting their activity.

scientific article published on 23 November 2015

Copper-triggered aggregation of ubiquitin

scientific article

Crystallographic analysis of metal-ion binding to human ubiquitin

scientific article

Differential Reactivity of Metal Binding Domains of Copper ATPases towards Cisplatin and Colocalization of Copper and Platinum

scientific article published on 30 May 2018

Duplications of an iron-sulphur tripeptide leads to the formation of a protoferredoxin.

scientific article published on 28 October 2016

Effect of Thioethers on DNA Platination bytrans-Platinum Complexes

scientific article published on 03 August 2011

Effect of chirality in platinum drugs

Effect of cisplatin on the transport activity of PII-type ATPases.

scientific article published in July 2017

Effect of in vivo post-translational modifications of the HMGB1 protein upon binding to platinated DNA: a molecular simulation study

scientific article

Folding studies of Cox17 reveal an important interplay of cysteine oxidation and copper binding

scientific article

Heavy metals toxicity: effect of cadmium ions on amyloid beta protein 1-42. Possible implications for Alzheimer's disease

scientific article published on 21 February 2014

Insights into the molecular mechanisms of protein platination from a case study: the reaction of anticancer platinum(II) iminoethers with horse heart cytochrome c.

scientific article published on 9 October 2007

Interaction between platinum complexes and a methionine motif found in copper transport proteins

scientific article published in January 2007

Intranasal delivery of dopamine to the striatum using glycol chitosan/sulfobutylether-β-cyclodextrin based nanoparticles.

scientific article

Investigation on the influence of (Z)-3-(2-(3-chlorophenyl)hydrazono)-5,6-dihydroxyindolin-2-one (PT2) on β-amyloid(1-40) aggregation and toxicity

scientific article

Mechanistic and Structural Basis for Inhibition of Copper Trafficking by Platinum Anticancer Drugs

scientific article published on 19 July 2019

Mechanistic insight into the inhibition of matrix metalloproteinases by platinum substrates.

scientific article

Metallochaperones and metal-transporting ATPases: a comparative analysis of sequences and structures

scientific article published on 01 February 2002

Methionine can favor DNA platination by trans-coordinated platinum antitumor drugs

scientific article published in January 2009

Molecular Recognition of Platinated DNA from Chromosomal HMGB1.

scientific article published on 10 July 2014

Monitoring Interactions inside Cells by Advanced Spectroscopies: Overview of Copper Transporters and Cisplatin.

scientific article published on 10 November 2017

Monitoring mobility in the early steps of unfolding: the case of oxidized cytochrome b(5) in the presence of 2 M guanidinium chloride

scientific article published on 01 June 2000

NMR structures of paramagnetic metalloproteins.

scientific article

Ortholog search of proteins involved in copper delivery to cytochrome C oxidase and functional analysis of paralogs and gene neighbors by genomic context

scientific article

Oxaliplatin Binding to Human Copper Chaperone Atox1 and Protein Dimerization

scientific article

Oxidation of Human Copper Chaperone Atox1 and Disulfide Bond Cleavage by Cisplatin and Glutathione

scientific article published on 06 September 2019

PREFACE: Contributions to platinum bioinorganic chemistry and beyond honoring Professor Giovanni Natile on the occasion of his 70th birthday

scientific article published in December 2015

Performance Assessment in Fingerprinting and Multi Component Quantitative NMR Analyses

scientific article

Platination of the copper transporter ATP7A involved in anticancer drug resistance

scientific article published in August 2014

Probing the Interaction of Cisplatin with the Human Copper Chaperone Atox1 by Solution and In-Cell NMR Spectroscopy

scientific article published on 24 October 2011

Solution structure and characterization of the heme chaperone CcmE

scientific article

Solution structure of CopC: a cupredoxin-like protein involved in copper homeostasis

scientific article

Solution structure of oxidized rat microsomal cytochrome b5 in the presence of 2 M guanidinium chloride: monitoring the early steps in protein unfolding

scientific article

Solution structure of the B form of oxidized rat microsomal cytochrome b5and backbone dynamics via15N rotating-frame NMR-relaxation measurements

scientific article published in 1999

Structural Determinants of Cisplatin and Transplatin Binding to the Met-Rich Motif of Ctr1: A Computational Spectroscopy Approach

scientific article

Structural Elucidation of Cisplatin and Hydrated cis-Diammineplatinum(II) Complex Conjugated with Cyanocobalamin by Liquid Chromatography with Electrospray Ionization-Mass Spectrometry and Multistage Mass Spectrometry

scientific article published on 09 October 2018

Structural biology of cisplatin complexes with cellular targets: the adduct with human copper chaperone atox1 in aqueous solution.

scientific article published on 8 August 2014

Structural interplay between calcium(II) and copper(II) binding to S100A13 protein

scientific article

Structural probing of Zn(II), Cd(II) and Hg(II) binding to human ubiquitin

scientific article

Tetrathiomolybdate inhibits the reaction of cisplatin with human copper chaperone Atox1

scientific article published on 01 May 2018

The Effects of Chronic Lifelong Activation of the AHR Pathway by Industrial Chemical Pollutants on Female Human Reproduction

scientific article

The auto-orientation in high magnetic fields of oxidized cytochrome b562 as source of constraints for solution structure determination

scientific article published on 01 August 2000

The evolutionarily conserved trimeric structure of CutA1 proteins suggests a role in signal transduction

scientific article

The reaction of a platinated methionine motif of CTR1 with cysteine and histidine is dependent upon the type of precursor platinum complex

scientific article published on 21 July 2015

The solution structure of oxidized rat microsomal cytochrome b5

scientific article

The unusually stable quaternary structure of human Cu,Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status

scientific article published on 23 August 2004

Translocation of platinum anticancer drugs by human copper ATPases ATP7A and ATP7B.

scientific article published on 27 December 2013

Ubiquitin Stability and the Lys 63-Linked Polyubiquitination Site Are Compromised on Copper Binding

scientific article published on 01 January 2007

Unusual interstrand Pt(S,S-diaminocyclohexane)-GG crosslink formed by rearrangement of a classical intrastrand crosslink within a DNA duplex

scientific article published in February 2010