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List of works by Karl-Heinz Storbeck

11-Ketotestosterone and 11-Ketodihydrotestosterone in Castration Resistant Prostate Cancer: Potent Androgens Which Can No Longer Be Ignored

scientific article published on 21 July 2016

11-Oxygenated C19 Steroids Are the Predominant Androgens in Polycystic Ovary Syndrome

scientific article published on 30 November 2016

11-Oxygenated androgen precursors are the preferred substrates for aldo-keto reductase 1C3 (AKR1C3): Implications for castration resistant prostate cancer

scientific article published on 21 June 2018

11-oxygenated estrogens are a novel class of human estrogens but do not contribute to the circulating estrogen pool

scientific article published on 19 December 2020

11β-Hydroxyandrostenedione: Downstream metabolism by 11βHSD, 17βHSD and SRD5A produces novel substrates in familiar pathways.

scientific article published on 23 December 2014

11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: a putative role in castration resistant prostate cancer?

scientific article published on 13 July 2013

11β-hydroxyandrostenedione returns to the steroid arena: biosynthesis, metabolism and function.

scientific article published on 25 October 2013

11β-hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione

scientific article published on 16 May 2013

16α-hydroxyprogesterone: origin, biosynthesis and receptor interaction.

scientific article

A comparative study of the androgenic properties of progesterone and the progestins, medroxyprogesterone acetate (MPA) and norethisterone acetate (NET-A).

scientific article

A new dawn for androgens: Novel lessons from 11-oxygenated C19 steroids.

scientific article

A single amino acid residue, Ala 105, confers 16alpha-hydroxylase activity to human cytochrome P450 17alpha-hydroxylase/17,20 lyase

scientific article published on 4 January 2010

Advances in the analytical methodologies: Profiling steroids in familiar pathways-challenging dogmas.

scientific article published on 10 April 2015

Allosteric interaction between 3β-hydroxysteroid dehydrogenase/Δ⁵-Δ⁴ isomerase and cytochrome b5 influences cofactor binding

scientific article

Analysis of multiple vitamin D metabolites by ultra-performance supercritical fluid chromatography-tandem mass spectrometry (UPSFC-MS/MS)

scientific article published on 18 April 2018

Bidirectional crosstalk between Hypoxia-Inducible Factor and glucocorticoid signalling in zebrafish larvae

scientific article published on 07 May 2020

CYP17 causes hypocortisolism in the South African Angora goat.

scientific article published on 17 September 2008

Characterization of a family 54 alpha-L-arabinofuranosidase from Aureobasidium pullulans.

scientific article published on 23 October 2007

Corrigendum to “The influence of Aspalathus linearis (Rooibos) and dihydrochalcones on adrenal steroidogenesis: Quantification of steroid intermediates and end products in H295R cells” [J. Steroid Biochem. Mol. Biol. 128 (2012) 128–138]

scientific article published in January 2013

Cortisol production in sheep is influenced by the functional expression of two cytochrome P450 17α-hydroxylase/17,20-lyase (CYP17) isoforms

scientific article published on 12 December 2012

Cytochrome P450 side-chain cleavage: insights gained from homology modeling

scientific article published on 12 January 2007

Cytochrome b(5) forms homomeric complexes in living cells

scientific article published on 31 July 2012

Cytochrome b5 augments 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase activity

scientific article published on 14 September 2011

Cytochrome b5 modulates multiple reactions in steroidogenesis by diverse mechanisms.

scientific article

Cytochrome b5: novel roles in steroidogenesis

scientific article published on 07 December 2012

Differential metabolism of clinically-relevant progestogens in cell lines and tissue: Implications for biological mechanisms

scientific article published on 26 February 2019

Evidence for the functional role of residues in the B'-C loop of baboon cytochrome P450 side-chain cleavage (CYP11A1) obtained by site-directed mutagenesis, kinetic analysis and homology modelling.

scientific article published in November 2006

Expression and activity profiling of the steroidogenic enzymes of glucocorticoid biosynthesis and the fdx1 co-factors in zebrafish

scientific article published on 01 April 2018

Fourth-Generation Progestins Inhibit 3β-Hydroxysteroid Dehydrogenase Type 2 and Modulate the Biosynthesis of Endogenous Steroids

scientific article

Genetic Disruption of 21-Hydroxylase in Zebrafish Causes Interrenal Hyperplasia

scientific article published on 13 September 2017

High-throughput analysis of 19 endogenous androgenic steroids by ultra-performance convergence chromatography tandem mass spectrometry.

scientific article

Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive review

scientific article published on 27 July 2019

Hypocortisolism in the South African angora goat: the role of 3betaHSD.

scientific article published on 4 August 2009

Intracrine androgen biosynthesis, metabolism and action revisited

scientific article published on 30 August 2017

MON-203 Local Activation of 11-Oxygenated Androgens by AKR1C3 Is the Predominant Source of Androgens in Human Female Adipose Tissue

Modified-Release and Conventional Glucocorticoids and Diurnal Androgen Excretion in Congenital Adrenal Hyperplasia.

scientific article published in June 2017

Progestins used in endocrine therapy and the implications for the biosynthesis and metabolism of endogenous steroid hormones.

scientific article published on 8 September 2016

Relative contribution of P450c17 towards the acute cortisol response: Lessons from sheep and goats

scientific article published on 15 January 2015

Rooibos influences glucocorticoid levels and steroid ratios in vivo and in vitro: a natural approach in the management of stress and metabolic disorders?

scientific article published on 11 September 2013

Steroid Metabolome Analysis in Disorders of Adrenal Steroid Biosynthesis and Metabolism

scientific article published on 01 December 2019

Steroid metabolism in breast cancer: Where are we and what are we missing?

scientific article

The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1

scientific article published on 03 July 2020

The development of an ultra performance liquid chromatography-coupled atmospheric pressure chemical ionization mass spectrometry assay for seven adrenal steroids

scientific article

The identification of two CYP17 alleles in the South African Angora goat

scientific article published on 01 January 2007

The influence of Aspalathus linearis (Rooibos) and dihydrochalcones on adrenal steroidogenesis: quantification of steroid intermediates and end products in H295R cells

scientific article

The influence of the amino acid substitution I98K on the catalytic activity of baboon cytochrome P450 side-chain cleavage (CYP11A1).

scientific article published in November 2004

The utility of ultra-high performance supercritical fluid chromatography-tandem mass spectrometry (UHPSFC-MS/MS) for clinically relevant steroid analysis.

scientific article published on 20 March 2018

Two CYP17 genes in the South African Angora goat (Capra hircus) - the identification of three genotypes that differ in copy number and steroidogenic output

scientific article published on 4 July 2008

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