List of works - Onur Boyman

A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells

scientific article

Activation of dendritic antigen-presenting cells expressing common heat shock protein receptor CD91 during induction of psoriasis.

scientific article published in June 2005

Adverse reactions to biologic agents and their medical management.

scientific article

Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.

scientific article published in July 2007

An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2

scientific article

Apremilast in Treatment-Refractory Recurrent Aphthous Stomatitis

scientific article published on 01 November 2019

Autoantibodies in COVID-19 correlate with antiviral humoral responses and distinct immune signatures

scientific article published on 01 April 2022

B and T lymphocyte attenuator regulates CD8+ T cell-intrinsic homeostasis and memory cell generation

scientific article published on 7 January 2007

Biologicals in atopic disease in pregnancy: an EAACI position paper

scientific article published on 18 March 2020

Bystander activation of CD4+ T cells

scientific article published in April 2010

Chemical Synthesis of Interleukin-2 and Disulfide Stabilizing Analogues

scientific article published on 07 February 2020

Considerations on Biologicals for Patients with allergic disease in times of the COVID-19 pandemic: an EAACI Statement

scientific article published on 05 June 2020

Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}

scholarly article

Cutting edge: IL-7 regulates the peripheral pool of adult ROR gamma+ lymphoid tissue inducer cells.

scientific article published on 27 July 2009

Cytokine complex-expanded natural killer cells improve allogeneic lung transplant function via depletion of donor dendritic cells

scientific article published on June 2013

Development of a novel class of interleukin-2 immunotherapies for metastatic cancer

scientific article published on 23 January 2019

Direct stimulation of T cells by membrane vesicles from antigen-presenting cells

scholarly article

EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders

scientific article published on 24 April 2015

Editorial overview: Allergy and hypersensitivity: Emerging concepts in allergy and type 2 immunity

scientific article published on 01 October 2018

Endogenous polyclonal anti-IL-1 antibody responses potentiate IL-1 activity during pathogenic inflammation.

scientific article published on 7 November 2016

Epidermal IL-15Rα acts as an endogenous antagonist of psoriasiform inflammation in mouse and man.

scientific article published on 09 September 2013

Epigenetic mechanisms of tumor resistance to immunotherapy

scientific article published on 23 August 2018

Erythropoiesis defect observed in STAT3 GOF patients with severe anemia

scientific article published on 17 December 2019

Establishment of a scalable microfluidic assay for characterization of population-based neutrophil chemotaxis

scientific article published on 23 January 2020

Evolution and function of interleukin-4 receptor signaling in adaptive immunity and neutrophils

scientific article published on 06 March 2020

Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'

scientific article

Exposure to avian coronavirus vaccines is associated with increased levels of SARS‐CoV ‐2‐cross‐reactive antibodies

Functional and phenotypic characterization of tetanus toxoid-specific human CD4+ T cells following re-immunization

scientific article published in April 2007

GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells.

scientific article

Group A Streptococcal DNase Sda1 Impairs Plasmacytoid Dendritic Cells' Type 1 Interferon Response

scientific article published on 10 December 2018

Homeostasis of memory T cells

scientific article published on June 2006

Homeostatic maintenance of T cells and natural killer cells ⬇️

scientific article published on March 30, 2012

Human natural killer cells prevent infectious mononucleosis features by targeting lytic Epstein-Barr virus infection

scientific article published on 19 December 2013

IL-17 receptor A and adenosine deaminase 2 deficiency in siblings with recurrent infections and chronic inflammation

scientific article published on 19 November 2015

IL-2- and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets

scientific article

IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25

scientific article

IL-4 receptor engagement in human neutrophils impairs their migration and extracellular trap formation

scientific article published on 12 February 2019

IL-7/anti-IL-7 mAb complexes restore T cell development and induce homeostatic T Cell expansion without lymphopenia

scientific article published on 01 June 2008

Immune modulation via T regulatory cell enhancement: disease-modifying therapies for autoimmunity and their potential for chronic allergic and inflammatory diseases - An EAACI position paper of the Task Force on Immunopharmacology (TIPCO)

scientific article published on 27 June 2020

Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells

scientific article

Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2.

scientific article published on November 2016

Inflammation-Induced CCR7 Oligomers Form Scaffolds to Integrate Distinct Signaling Pathways for Efficient Cell Migration

scientific article published in January 2016

Interleukin-2 signals converge in a lymphoid-dendritic cell pathway that promotes anticancer immunity

scientific article published on 01 September 2020

Interleukin-2: Biology, Design and Application

scientific article

Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage

scientific article published on 20 August 2013

Limitations of IL-2 and rapamycin in immunotherapy of type 1 diabetes

scientific article published on 13 May 2013

Memory B Cells Activate Brain-Homing, Autoreactive CD4 T Cells in Multiple Sclerosis

scientific article published on 30 August 2018

Nanoparticle-Coupled Topical Methotrexate Can Normalize Immune Responses and Induce Tissue Remodeling in Psoriasis

scientific article published on 31 October 2019

Persistent complement dysregulation with signs of thromboinflammation in active Long Covid

scientific article published on 18 January 2024

Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production.

scientific article

Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease

scientific article published on December 2006

Profound dysregulation of T cell homeostasis and function in patients with severe COVID‐19

scientific article published in 2021

Rapid expansion of Treg cells protects from collateral colitis following a viral trigger

scientific article published on 23 March 2020

Receptor-gated IL-2 delivery by an anti-human IL-2 antibody activates regulatory T cells in three different species

scientific article published on 01 December 2020

Regulation of neutrophils in type 2 immune responses

scientific article published on 14 July 2018

Research needs in allergy: an EAACI position paper, in collaboration with EFA.

scientific article published on 2 November 2012

Selective stimulation of T cell subsets with antibody-cytokine immune complexes

scientific article

Selectively expanding subsets of T cells in mice by injection of interleukin-2/antibody complexes: implications for transplantation tolerance

scientific article published on May 2012

Signature of long-lived memory CD8<sup>+</sup> T cells in acute SARS-CoV-2 infection

scientific article published on 07 December 2021

Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype

scholarly article

Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

scientific article

Systematic Review of Safety and Efficacy of Rituximab in Treating Immune-Mediated Disorders

scientific article published on 06 September 2019

Systematic review of safety and efficacy of belimumab in treating immune-mediated disorders

scientific article published on 26 December 2020

T cell homeostasis.

scientific article published on 25 March 2008

The Histone Methyltransferase Ezh2 Controls Mechanisms of Adaptive Resistance to Tumor Immunotherapy.

scientific article

The Regulatory Effects of Interleukin-4 Receptor Signaling on Neutrophils in Type 2 Immune Responses

scientific article published on 24 October 2019

The Role of Interleukin-2 in Memory CD8 Cell Differentiation ⬇️

scientific article published on January 1, 2010

The Swiss National Registry for Primary Immunodeficiencies: report on the first 6 years' activity from 2008 to 2014.

scientific article

The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.

scientific article

The pathogenic role of tissue-resident immune cells in psoriasis.

scientific article published on 2 January 2007

The proton-activated receptor GPR4 modulates intestinal inflammation

scientific article published on 9 November 2017

The role of chemokines in cancer immune surveillance by the adaptive immune system.

scientific article

The role of cytokines in T-cell memory in health and disease.

scientific article

The role of interleukin-2 during homeostasis and activation of the immune system

scientific article

The suppressive role of IL-10 in contact and atopic dermatitis

scientific article published on 01 January 2012

The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity

scientific article published on 02 July 2018

Type 2 Interleukin-4 Receptor Signaling in Neutrophils Antagonizes Their Expansion and Migration during Infection and Inflammation.

scientific article published on July 2016

T‐cell recovery and evidence of persistent immune activation 12 months after severe <scp>COVID</scp>‐19

scientific article published in 2022

Use of enhanced interleukin-2 formulations for improved immunotherapy against cancer.

scientific article published on 29 September 2014

List of works by Onur Boyman

A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells

Activation of dendritic antigen-presenting cells expressing common heat shock protein receptor CD91 during induction of psoriasis.

Adverse reactions to biologic agents and their medical management.

Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.

An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2

Apremilast in Treatment-Refractory Recurrent Aphthous Stomatitis

Autoantibodies in COVID-19 correlate with antiviral humoral responses and distinct immune signatures

B and T lymphocyte attenuator regulates CD8+ T cell-intrinsic homeostasis and memory cell generation

Biologicals in atopic disease in pregnancy: an EAACI position paper

Bystander activation of CD4+ T cells

Chemical Synthesis of Interleukin-2 and Disulfide Stabilizing Analogues

Considerations on Biologicals for Patients with allergic disease in times of the COVID-19 pandemic: an EAACI Statement

Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}

Cutting edge: IL-7 regulates the peripheral pool of adult ROR gamma+ lymphoid tissue inducer cells.

Cytokine complex-expanded natural killer cells improve allogeneic lung transplant function via depletion of donor dendritic cells

Development of a novel class of interleukin-2 immunotherapies for metastatic cancer

Direct stimulation of T cells by membrane vesicles from antigen-presenting cells

EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders

Editorial overview: Allergy and hypersensitivity: Emerging concepts in allergy and type 2 immunity

Endogenous polyclonal anti-IL-1 antibody responses potentiate IL-1 activity during pathogenic inflammation.

Epidermal IL-15Rα acts as an endogenous antagonist of psoriasiform inflammation in mouse and man.

Epigenetic mechanisms of tumor resistance to immunotherapy

Erythropoiesis defect observed in STAT3 GOF patients with severe anemia

Establishment of a scalable microfluidic assay for characterization of population-based neutrophil chemotaxis

Evolution and function of interleukin-4 receptor signaling in adaptive immunity and neutrophils

Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'

Exposure to avian coronavirus vaccines is associated with increased levels of SARS‐CoV ‐2‐cross‐reactive antibodies

Functional and phenotypic characterization of tetanus toxoid-specific human CD4+ T cells following re-immunization

GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells.

Group A Streptococcal DNase Sda1 Impairs Plasmacytoid Dendritic Cells' Type 1 Interferon Response

Homeostasis of memory T cells

Homeostatic maintenance of T cells and natural killer cells ⬇️

Human natural killer cells prevent infectious mononucleosis features by targeting lytic Epstein-Barr virus infection

IL-17 receptor A and adenosine deaminase 2 deficiency in siblings with recurrent infections and chronic inflammation

IL-2- and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets

IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25

IL-4 receptor engagement in human neutrophils impairs their migration and extracellular trap formation

IL-7/anti-IL-7 mAb complexes restore T cell development and induce homeostatic T Cell expansion without lymphopenia

Immune modulation via T regulatory cell enhancement: disease-modifying therapies for autoimmunity and their potential for chronic allergic and inflammatory diseases - An EAACI position paper of the Task Force on Immunopharmacology (TIPCO)

Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells

Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2.

Inflammation-Induced CCR7 Oligomers Form Scaffolds to Integrate Distinct Signaling Pathways for Efficient Cell Migration

Interleukin-2 signals converge in a lymphoid-dendritic cell pathway that promotes anticancer immunity

Interleukin-2: Biology, Design and Application

Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage

Limitations of IL-2 and rapamycin in immunotherapy of type 1 diabetes

Memory B Cells Activate Brain-Homing, Autoreactive CD4 T Cells in Multiple Sclerosis

Nanoparticle-Coupled Topical Methotrexate Can Normalize Immune Responses and Induce Tissue Remodeling in Psoriasis

Persistent complement dysregulation with signs of thromboinflammation in active Long Covid

Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production.

Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease

Profound dysregulation of T cell homeostasis and function in patients with severe COVID‐19

Rapid expansion of Treg cells protects from collateral colitis following a viral trigger

Receptor-gated IL-2 delivery by an anti-human IL-2 antibody activates regulatory T cells in three different species

Regulation of neutrophils in type 2 immune responses

Research needs in allergy: an EAACI position paper, in collaboration with EFA.

Selective stimulation of T cell subsets with antibody-cytokine immune complexes

Selectively expanding subsets of T cells in mice by injection of interleukin-2/antibody complexes: implications for transplantation tolerance

Signature of long-lived memory CD8<sup>+</sup> T cells in acute SARS-CoV-2 infection

Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype

Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

Systematic Review of Safety and Efficacy of Rituximab in Treating Immune-Mediated Disorders

Systematic review of safety and efficacy of belimumab in treating immune-mediated disorders

T cell homeostasis.

The Histone Methyltransferase Ezh2 Controls Mechanisms of Adaptive Resistance to Tumor Immunotherapy.

The Regulatory Effects of Interleukin-4 Receptor Signaling on Neutrophils in Type 2 Immune Responses

The Role of Interleukin-2 in Memory CD8 Cell Differentiation ⬇️

The Swiss National Registry for Primary Immunodeficiencies: report on the first 6 years' activity from 2008 to 2014.

The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.

The pathogenic role of tissue-resident immune cells in psoriasis.

The proton-activated receptor GPR4 modulates intestinal inflammation

The role of chemokines in cancer immune surveillance by the adaptive immune system.

The role of cytokines in T-cell memory in health and disease.

The role of interleukin-2 during homeostasis and activation of the immune system

The suppressive role of IL-10 in contact and atopic dermatitis

The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity

Type 2 Interleukin-4 Receptor Signaling in Neutrophils Antagonizes Their Expansion and Migration during Infection and Inflammation.

T‐cell recovery and evidence of persistent immune activation 12 months after severe <scp>COVID</scp>‐19

Use of enhanced interleukin-2 formulations for improved immunotherapy against cancer.