List of works - Colin Selman

A double whammy for aging? Rapamycin extends lifespan and inhibits cancer in inbred female mice

scientific article published in January 2012

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

scientific article

Aging in the wild: Insights from free-living and non-model organisms

scientific article published on 21 September 2015

Alterations in tissue aerobic capacity may play a role in premigratory fattening in shorebirds.

scientific article published on March 2005

Antioxidant enzyme activities, lipid peroxidation, and DNA oxidative damage: the effects of short-term voluntary wheel running

scientific article

Association between mammalian lifespan and circadian free-running period: the circadian resonance hypothesis revisited

scientific article

Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice

scientific article

Chronic helminth infection burden differentially affects haematopoietic cell development while ageing selectively impairs adaptive responses to infection.

scientific article published on 28 February 2018

Circadian desynchrony and metabolic dysfunction; did light pollution make us fat?

scientific article published on 07 October 2011

Comment on "Brain IRS2 signaling coordinates life span and nutrient homeostasis"

scientific article published on 01 May 2008

Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice.

scientific article published in May 2018

Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice.

scientific article

Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost

article

Deleterious consequences of antioxidant supplementation on lifespan in a wild-derived mammal

scientific article published on 03 July 2013

Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity

scientific article published on 28 November 2018

Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.

scientific article published on 08 December 2008

Dietary restriction and the pursuit of effective mimetics.

scientific article published on 10 January 2014

Dietary restriction increases skeletal muscle mitochondrial respiration but not mitochondrial content in C57BL/6 mice

scientific article published on 28 December 2011

Disentangling the effect of dietary restriction on mitochondrial function using recombinant inbred mice

scientific article

Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons

scientific article published on November 2009

Doxorubicin treatment in vivo activates caspase-12 mediated cardiac apoptosis in both male and female rats

scientific article published in November 2004

Effect of long-term cold exposure on antioxidant enzyme activities in a small mammal

scientific article published on 01 April 2000

Effect of pregnancy on exposure to malaria mosquitoes

scientific article published in June 2000

Effects of a specific MCHR1 antagonist (GW803430) on energy budget and glucose metabolism in diet-induced obese mice

scientific article published on 2 December 2013

Effects of dietary calcium restriction and acute exercise on the antioxidant enzyme system and oxidative stress in rat diaphragm

scientific article published on 5 February 2004

Energy expenditure of calorically restricted rats is higher than predicted from their altered body composition

scientific article published on 16 March 2005

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

scientific article

Evidence that hematopoietic stem cell function is preserved during aging in long-lived S6K1 mutant mice

scientific article

Evolutionary conservation of regulated longevity assurance mechanisms

scientific article published on January 2007

Exercise by lifelong voluntary wheel running reduces subsarcolemmal and interfibrillar mitochondrial hydrogen peroxide production in the heart

scientific article published on 28 July 2005

Expenditure freeze: the metabolic response of small mammals to cold environments

article

Extracellular Vesicles, Ageing, and Therapeutic Interventions

scientific article published on 18 August 2018

Fibroblasts derived from long-lived insulin receptor substrate 1 null mice are not resistant to multiple forms of stress

scientific article

Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production

scientific article

Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity.

scientific article published on 4 March 2016

Increased hepatic apoptosis during short-term caloric restriction is not associated with an enhancement in caspase levels

scientific article published on 01 August 2003

Individuals with higher metabolic rates have lower levels of reactive oxygen species in vivo

scientific article published on September 2015

Interventions for age-related diseases: Shifting the paradigm

scientific article

Life-long vitamin C supplementation in combination with cold exposure does not affect oxidative damage or lifespan in mice, but decreases expression of antioxidant protection genes.

scientific article published on 7 November 2006

Lifelong alpha-tocopherol supplementation increases the median life span of C57BL/6 mice in the cold but has only minor effects on oxidative damage

scientific article published in February 2008

Lifespan modulation in mice and the confounding effects of genetic background.

scientific article

Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake

scientific article

Longevity of insulin receptor substrate1 null mice is not associated with increased basal antioxidant protection or reduced oxidative damage

scientific article published on 29 February 2012

Mammalian models of extended healthy lifespan

scientific article

Marker-dependent associations among oxidative stress, growth and survival during early life in a wild mammal.

scientific article published in October 2016

Meta-analysis of gene expression in the mouse liver reveals biomarkers associated with inflammation increased early during aging

scientific article published on 13 June 2012

Metabotyping of long-lived mice using 1H NMR spectroscopy

scientific article published on 27 February 2012

Nutritional geometry provides food for thought.

scientific article

Oxidative damage increases with reproductive energy expenditure and is reduced by food-supplementation

scientific article published on 20 December 2012

Oxidative damage, ageing, and life-history evolution: where now?

scientific article

Oxidative stress and life histories: unresolved issues and current needs.

scientific article published on 17 November 2015

Oxidative stress and the evolution of sex differences in life span and ageing in the decorated cricket, Gryllodes sigillatus.

scientific article published on 10 October 2012

Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice

scientific article published on 29 March 2007

Photoperiodic regulation in a wild-derived mouse strain

scientific article published on 25 March 2020

Physical activity and resting metabolic rate.

scientific article published on August 2003

Physiology: An atypical switch for metabolism and ageing.

scientific article

Plasma markers of oxidative stress are uncorrelated in a wild mammal

scientific article published on 19 October 2015

Proteostasis and ageing: insights from long-lived mutant mice.

scientific article

Putting a strain on diversity

article

Replication of extended lifespan phenotype in mice with deletion of insulin receptor substrate 1.

scientific article

Role of central nervous system and ovarian insulin receptor substrate 2 signaling in female reproductive function in the mouse

scientific article published on 28 February 2007

Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice?

scientific article published on February 2008

Short-term caloric restriction and regulatory proteins of apoptosis in heart, skeletal muscle and kidney of Fischer 344 rats

scientific article published on 01 January 2003

Short-term caloric restriction and sites of oxygen radical generation in kidney and skeletal muscle mitochondria

scientific article published on 01 June 2004

Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios

scientific article (publication date: October 2016)

Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice

scientific article published on 11 March 2020

The RCR and ATP/O Indices Can Give Contradictory Messages about Mitochondrial Efficiency

scientific article published on 01 September 2018

The consequences of acute cold exposure on protein oxidation and proteasome activity in short-tailed field voles, microtus agrestis

scientific article published in July 2002

The free-radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan.

scientific article

The impact of acute caloric restriction on the metabolic phenotype in male C57BL/6 and DBA/2 mice

scientific article published on 12 January 2010

The impact of experimentally elevated energy expenditure on oxidative stress and lifespan in the short-tailed field vole Microtus agrestis.

scientific article published in August 2008

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing

scientific article published on 12 March 2020

Thermoregulatory responses of two mouse Mus musculus strains selectively bred for high and low food intake

scientific article published on 01 November 2001

Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer

scientific article

Using doubly-labeled water to measure energy expenditure in an important small ectotherm Drosophila melanogaster.

scientific article

Variation in Metabolic Rate among Individuals Is Related to Tissue-Specific Differences in Mitochondrial Leak Respiration

scientific article published on 27 September 2016

Variation in the link between oxygen consumption and ATP production, and its relevance for animal performance

scientific article

Vitamin E supplementation and mammalian lifespan

scientific article published on May 2010

List of works by Colin Selman

A double whammy for aging? Rapamycin extends lifespan and inhibits cancer in inbred female mice

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

Aging in the wild: Insights from free-living and non-model organisms

Alterations in tissue aerobic capacity may play a role in premigratory fattening in shorebirds.

Antioxidant enzyme activities, lipid peroxidation, and DNA oxidative damage: the effects of short-term voluntary wheel running

Association between mammalian lifespan and circadian free-running period: the circadian resonance hypothesis revisited

Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice

Chronic helminth infection burden differentially affects haematopoietic cell development while ageing selectively impairs adaptive responses to infection.

Circadian desynchrony and metabolic dysfunction; did light pollution make us fat?

Comment on "Brain IRS2 signaling coordinates life span and nutrient homeostasis"

Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice.

Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice.

Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost

Deleterious consequences of antioxidant supplementation on lifespan in a wild-derived mammal

Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity

Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.

Dietary restriction and the pursuit of effective mimetics.

Dietary restriction increases skeletal muscle mitochondrial respiration but not mitochondrial content in C57BL/6 mice

Disentangling the effect of dietary restriction on mitochondrial function using recombinant inbred mice

Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons

Doxorubicin treatment in vivo activates caspase-12 mediated cardiac apoptosis in both male and female rats

Effect of long-term cold exposure on antioxidant enzyme activities in a small mammal

Effect of pregnancy on exposure to malaria mosquitoes

Effects of a specific MCHR1 antagonist (GW803430) on energy budget and glucose metabolism in diet-induced obese mice

Effects of dietary calcium restriction and acute exercise on the antioxidant enzyme system and oxidative stress in rat diaphragm

Energy expenditure of calorically restricted rats is higher than predicted from their altered body composition

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

Evidence that hematopoietic stem cell function is preserved during aging in long-lived S6K1 mutant mice

Evolutionary conservation of regulated longevity assurance mechanisms

Exercise by lifelong voluntary wheel running reduces subsarcolemmal and interfibrillar mitochondrial hydrogen peroxide production in the heart

Expenditure freeze: the metabolic response of small mammals to cold environments

Extracellular Vesicles, Ageing, and Therapeutic Interventions

Fibroblasts derived from long-lived insulin receptor substrate 1 null mice are not resistant to multiple forms of stress

Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production

Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity.

Increased hepatic apoptosis during short-term caloric restriction is not associated with an enhancement in caspase levels

Individuals with higher metabolic rates have lower levels of reactive oxygen species in vivo

Interventions for age-related diseases: Shifting the paradigm

Life-long vitamin C supplementation in combination with cold exposure does not affect oxidative damage or lifespan in mice, but decreases expression of antioxidant protection genes.

Lifelong alpha-tocopherol supplementation increases the median life span of C57BL/6 mice in the cold but has only minor effects on oxidative damage

Lifespan modulation in mice and the confounding effects of genetic background.

Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake

Longevity of insulin receptor substrate1 null mice is not associated with increased basal antioxidant protection or reduced oxidative damage

Mammalian models of extended healthy lifespan

Marker-dependent associations among oxidative stress, growth and survival during early life in a wild mammal.

Meta-analysis of gene expression in the mouse liver reveals biomarkers associated with inflammation increased early during aging

Metabotyping of long-lived mice using 1H NMR spectroscopy

Nutritional geometry provides food for thought.

Oxidative damage increases with reproductive energy expenditure and is reduced by food-supplementation

Oxidative damage, ageing, and life-history evolution: where now?

Oxidative stress and life histories: unresolved issues and current needs.

Oxidative stress and the evolution of sex differences in life span and ageing in the decorated cricket, Gryllodes sigillatus.

Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice

Photoperiodic regulation in a wild-derived mouse strain

Physical activity and resting metabolic rate.

Physiology: An atypical switch for metabolism and ageing.

Plasma markers of oxidative stress are uncorrelated in a wild mammal

Proteostasis and ageing: insights from long-lived mutant mice.

Putting a strain on diversity

Replication of extended lifespan phenotype in mice with deletion of insulin receptor substrate 1.

Role of central nervous system and ovarian insulin receptor substrate 2 signaling in female reproductive function in the mouse

Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice?

Short-term caloric restriction and regulatory proteins of apoptosis in heart, skeletal muscle and kidney of Fischer 344 rats

Short-term caloric restriction and sites of oxygen radical generation in kidney and skeletal muscle mitochondria

Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios

Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice

The RCR and ATP/O Indices Can Give Contradictory Messages about Mitochondrial Efficiency

The consequences of acute cold exposure on protein oxidation and proteasome activity in short-tailed field voles, microtus agrestis

The free-radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan.

The impact of acute caloric restriction on the metabolic phenotype in male C57BL/6 and DBA/2 mice

The impact of experimentally elevated energy expenditure on oxidative stress and lifespan in the short-tailed field vole Microtus agrestis.

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing

Thermoregulatory responses of two mouse Mus musculus strains selectively bred for high and low food intake

Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer

Using doubly-labeled water to measure energy expenditure in an important small ectotherm Drosophila melanogaster.

Variation in Metabolic Rate among Individuals Is Related to Tissue-Specific Differences in Mitochondrial Leak Respiration

Variation in the link between oxygen consumption and ATP production, and its relevance for animal performance

Vitamin E supplementation and mammalian lifespan