List of works - Toni T Seppälä

Amyloid-β and Tau Dynamics in Human Brain Interstitial Fluid in Patients with Suspected Normal Pressure Hydrocephalus

scientific article

Analysis in the Prospective Lynch Syndrome Database identifies sarcoma as part of the Lynch syndrome tumor spectrum

scientific article published on 24 July 2020

Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome

scientific article published on 08 January 2020

Body Weight, Physical Activity, and Risk of Cancer in Lynch Syndrome

scientific article

CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings

scientific article published on 18 April 2012

Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database

scientific article published on 9 December 2015

Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial

scientific article published on 01 June 2020

Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database

scientific article published on 28 July 2017

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

scientific article published on 24 July 2019

Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus

scientific article

Coexisting ipsilateral right femoral hernia and incarcerated obturator hernia

scientific article

Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report

scientific article published on 10 October 2017

Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer

scientific article

Combined prognostic value of CD274 (PD-L1)/PDCDI (PD-1) expression and immune cell infiltration in colorectal cancer as per mismatch repair status

scientific article published on 05 February 2019

Comparison between clinical diagnosis and CSF biomarkers of Alzheimer disease in elderly patients with late onset psychosis: Helsinki Old Age Psychosis Study (HOPS).

scientific article published on 15 April 2013

Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

scientific article published on 20 July 2020

De Garengeot's hernia: 40 years after Bassini inguinal hernioplasty

scientific article published on 2 March 2015

Early diagnosis of Alzheimer's disease

scientific article published in January 2013

Epidemiological, clinical and molecular characterization of Lynch-like syndrome: A population-based study

scientific article published on 07 January 2019

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

scientific article published on 21 September 2020

Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers

scientific article published on 21 March 2019

Immunoscore in mismatch repair-proficient and -deficient colon cancer.

scientific article published on 19 July 2017

Incidence and management of patients with colorectal cancer and synchronous and metachronous colorectal metastases: a population-based study

scientific article published on 16 June 2020

Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database

scientific article published on 3 June 2016

Incident colorectal cancer in Lynch syndrome is usually not preceded by compromised quality of colonoscopy

scientific article published on 12 December 2019

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report

scientific article published on 28 February 2019

Longitudinal changes of CSF biomarkers in Alzheimer's disease

scientific article published in January 2011

No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies

scientific article published on 29 July 2018

Prognostic Value of Immune Environment Analysis in Small Bowel Adenocarcinomas with Verified Mutational Landscape and Predisposing Conditions

scientific article published on 23 July 2020

Recent advances in Lynch syndrome

scientific article published on 08 August 2020

Response to Tolva et al

scientific article published on 05 December 2019

Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

scientific article published on 06 September 2019

Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database

scientific article published on 18 July 2020

Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

scientific article published on 01 December 2020

Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report

scientific article published on 14 October 2019

The "unnatural" history of colorectal cancer in Lynch syndrome: lessons from colonoscopy surveillance

scientific article published on 19 July 2020

The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution

scientific article published on 21 September 2020

Uptake of genetic testing by the children of Lynch syndrome variant carriers across three generations.

scientific article published on 23 August 2017

[Are there enough medical scientists in Finland?]

scientific article published on 01 January 2011

List of works by Toni T Seppälä

Amyloid-β and Tau Dynamics in Human Brain Interstitial Fluid in Patients with Suspected Normal Pressure Hydrocephalus

Analysis in the Prospective Lynch Syndrome Database identifies sarcoma as part of the Lynch syndrome tumor spectrum

Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome

Body Weight, Physical Activity, and Risk of Cancer in Lynch Syndrome

CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings

Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database

Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial

Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus

Coexisting ipsilateral right femoral hernia and incarcerated obturator hernia

Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report

Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer

Combined prognostic value of CD274 (PD-L1)/PDCDI (PD-1) expression and immune cell infiltration in colorectal cancer as per mismatch repair status

Comparison between clinical diagnosis and CSF biomarkers of Alzheimer disease in elderly patients with late onset psychosis: Helsinki Old Age Psychosis Study (HOPS).

Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

De Garengeot's hernia: 40 years after Bassini inguinal hernioplasty

Early diagnosis of Alzheimer's disease

Epidemiological, clinical and molecular characterization of Lynch-like syndrome: A population-based study

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers

Immunoscore in mismatch repair-proficient and -deficient colon cancer.

Incidence and management of patients with colorectal cancer and synchronous and metachronous colorectal metastases: a population-based study

Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database

Incident colorectal cancer in Lynch syndrome is usually not preceded by compromised quality of colonoscopy

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report

Longitudinal changes of CSF biomarkers in Alzheimer's disease

No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies

Prognostic Value of Immune Environment Analysis in Small Bowel Adenocarcinomas with Verified Mutational Landscape and Predisposing Conditions

Recent advances in Lynch syndrome

Response to Tolva et al

Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database

Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report

The "unnatural" history of colorectal cancer in Lynch syndrome: lessons from colonoscopy surveillance

The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution

Uptake of genetic testing by the children of Lynch syndrome variant carriers across three generations.

[Are there enough medical scientists in Finland?]

[Diagnosis and treatment of Lynch syndrome]