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List of works by Jing-jer Lin

A Fluorescent Anti-Cancer Agent, 3,6-bis(1-methyl-4-vinylpyridinium) Carbazole Diiodide, Stains G-Quadruplexes in Cells and Inhibits Tumor Growth.

scientific article published on January 2015

A novel carbazole derivative, BMVC: a potential antitumor agent and fluorescence marker of cancer cells.

scientific article published on September 2004

A trans-acting gene is required for the phenotypic expression of a tyrosinase gene in Streptomyces

scientific article published on 01 May 1988

Activation of human telomerase reverse transcriptase expression by some new symmetrical bis-substituted derivatives of the anthraquinone

scientific article

An in vitro assay for saccharomyces telomerase requires EST1 ⬇️

scientific article published on June 30, 1995

Association of pituitary tumor transforming gene expression with early oral tumorigenesis and malignant progression of precancerous lesions

scientific article published on 10 November 2010

Chromosome positional effects of gene expressions after cellular senescence.

scientific article published on January 2004

Conformational transition of a hairpin structure to G-quadruplex within the WNT1 gene promoter

scientific article published on 24 December 2014

Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution

scientific article (publication date: 23 May 2003)

Crystallization and preliminary crystallographic analysis of yeast cytosine deaminase

scientific article published on 25 April 2003

Depleting components of the THO complex causes increased telomere length by reducing the expression of the telomere-associated protein Rif1p

scientific article published on 20 March 2012

Design and synthesis of class-selective activity probes for protein tyrosine phosphatases

scientific article published in January 2002

Design, synthesis and evaluation of telomerase inhibitory, hTERT repressing, and anti-proliferation activities of symmetrical 1,8-disubstituted amidoanthraquinones

scientific article published on 01 February 2012

Development and evaluation of novel phosphotyrosine mimetic inhibitors targeting the Src homology 2 domain of signaling lymphocytic activation molecule (SLAM) associated protein

scientific article published on 19 March 2013

Direct evidence of mitochondrial G-quadruplex DNA by using fluorescent anti-cancer agents.

scientific article

Exposure of single-stranded telomeric DNA causes G2/M cell cycle arrest in Saccharomyces cerevisiae

scientific article

Facile synthesis toward the construction of an activity probe library for glycosidases

scientific article published on 18 January 2006

Genetic analysis reveals essential and non-essential amino acids within the telomeric DNA-binding interface of Cdc13p

scientific article

H3K4 methylation at active genes mitigates transcription-replication conflicts during replication stress

scientific article published on 10 February 2020

Human telomerase inhibition and cytotoxicity of regioisomeric disubstituted amidoanthraquinones and aminoanthraquinones.

scientific article published on March 2005

Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validation

scientific article published on 15 December 2015

Induction of global stress response in Saccharomyces cerevisiae cells lacking telomerase

scientific article published on 01 March 2002

Induction of senescence in cancer cells by the G-quadruplex stabilizer, BMVC4, is independent of its telomerase inhibitory activity

scientific article

Inhibition of cancer cell migration and invasion through suppressing the Wnt1-mediating signal pathway by G-quadruplex structure stabilizers

scientific article

Interaction of Saccharomyces Cdc13p with Pol1p, Imp4p, Sir4p and Zds2p is involved in telomere replication, telomere maintenance and cell growth control

scientific article published on 23 January 2004

Isolation and characterization of two Saccharomyces cerevisiae genes that encode proteins that bind to (TG1-3)n single strand telomeric DNA in vitro

scientific article

Multiple Pif1 helicases are required to sequentially disrupt G-quadruplex structure and unwind duplex DNA

scientific article published on 11 April 2016

NSC746364, NSC746365, and NSC746366: the spectra of cytotoxicity and molecular correlates of response to telomerase activity.

scientific article published on February 2010

Overexpression of the pituitary tumor transforming gene induces p53-dependent senescence through activating DNA damage response pathway in normal human fibroblasts

scientific article

Pif1 regulates telomere length by preferentially removing telomerase from long telomere ends

scientific article

Rapid and selective isolation of beta-xylosidase through an activity-based chemical approach.

scientific article published in February 2006

Selective activation of SHP2 activity by cisplatin revealed by a novel chemical probe-based assay.

scientific article

Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α ⬇️

scientific article published on September 28, 2010

Structure-based design, synthesis and biological evaluation of novel anthra[1,2-d]imidazole-6,11-dione homologues as potential antitumor agents.

scientific article published on 9 August 2013

Structure-based design, synthesis and evaluation of novel anthra[1,2-d]imidazole-6,11-dione derivatives as telomerase inhibitors and potential for cancer polypharmacology.

scientific article published on 29 November 2012

Studies on anthracenes. 1. Human telomerase inhibition and lipid peroxidation of 9-acyloxy 1,5-dichloroanthracene derivatives

scientific article published in August 2001

Study of the preferred modification sites of the quinone methide intermediate resulting from the latent trapping device of the activity probes for hydrolases

scientific article published in January 2005

Synthesis and cytotoxic properties of 4,11-bis[(aminoethyl)amino]anthra[2,3-b]thiophene-5,10-diones, novel analogues of antitumor anthracene-9,10-diones

scientific article

Synthesis and human telomerase inhibition of a series of regioisomeric disubstituted amidoanthraquinones

scientific article published on 01 February 2007

Synthesis, Telomerase Evaluation and Anti‐Proliferative Studies on Various Series of Diaminoanthraquinone‐Linked Aminoacyl Residue Derivatives ⬇️

scientific article published on September 29, 2011

Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives.

scientific article

Telomere and telomerase as targets for anti-cancer and regeneration therapies

scientific article

Telomeric DNA binding proteins.

scientific article

Telomeric transcripts stimulate telomere recombination to suppress senescence in cells lacking telomerase

scientific article published on 18 February 2014

Ten1p promotes the telomeric DNA-binding activity of Cdc13p: implication for its function in telomere length regulation

scientific article

The U3 small nucleolar ribonucleoprotein component Imp4p is a telomeric DNA-binding protein

scientific article

The addition of a spin column step in the telomeric repeat application protocol removes telomerase inhibitors

scientific article published on 23 March 2015

The serine protease inhibitor serpinB2 binds and stabilizes p21 in senescent cells

scientific article published on 9 August 2017

The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation.

scientific article

Yin Yang 1 is a target of microRNA-34 family and contributes to gastric carcinogenesis

scientific article

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