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List of works by David Zappulla

A 4-base pair core-enclosing helix in telomerase RNA is essential for activity and for binding to the TERT catalytic protein subunit

scientific article published on 12 October 2020

A flexible template boundary element in the RNA subunit of fission yeast telomerase

scientific article published on 23 June 2008

A miniature yeast telomerase RNA functions in vivo and reconstitutes activity in vitro

scientific article

A second essential function of the Est1-binding arm of yeast telomerase RNA.

scientific article published on 3 March 2015

Identification of novel noncoding transcripts in telomerase-negative yeast using RNA-seq.

scientific article published on 20 January 2016

Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13p

scientific article

Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP.

scientific article

One-hybrid screens at the Saccharomyces cerevisiae HMR locus identify novel transcriptional silencing factors

scientific article published in January 2004

Physical Connectivity Mapping by Circular Permutation of Human Telomerase RNA Reveals New Regions Critical for Activity and Processivity

scientific article

RNA as a flexible scaffold for proteins: yeast telomerase and beyond.

scientific article

RNA connectivity requirements between conserved elements in the core of the yeast telomerase RNP.

scientific article published on 15 October 2013

Refined secondary-structure models of the core of yeast and human telomerase RNAs directed by SHAPE.

scientific article

Repositioning the Sm-Binding Site in Saccharomyces cerevisiae Telomerase RNA Reveals RNP Organizational Flexibility and Sm-Directed 3'-End Formation

scientific article published on 29 February 2020

Rtt107/Esc4 binds silent chromatin and DNA repair proteins using different BRCT motifs

scientific article

Stiffened yeast telomerase RNA supports RNP function in vitro and in vivo

scientific article

Structural Insights into Yeast Telomerase Recruitment to Telomeres.

scientific article published on 27 December 2017

The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae.

scientific article