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List of works by Daniel Fazakerley

A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling

scientific article published on 10 February 2009

A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling

scientific article published on 18 March 2009

Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo

scientific article

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

scientific article published on 13 January 2017

Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes.

scientific article published on 29 December 2011

An improved Akt reporter reveals intra- and inter-cellular heterogeneity and oscillations in signal transduction.

scientific article published on 29 June 2017

Circulating AFABP promotes insulin secretion

scientific article published on 06 July 2015

Direction pathway analysis of large-scale proteomics data reveals novel features of the insulin action pathway

scientific article

Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin

scientific article published on 21 January 2020

Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2.

scientific article published on 16 May 2013

Exposure to solar ultraviolet radiation limits diet-induced weight gain, increases liver triglycerides and prevents the early signs of cardiovascular disease in mice

scientific article published on 28 February 2019

GLUT4 exocytosis.

scientific article published on December 2011

Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates.

scientific article

Global redox proteome and phosphoproteome analysis reveals redox switch in Akt

scientific article published on 02 December 2019

Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity

scientific article

Insulin regulates Rab3-Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes

scientific article published on 30 May 2015

Insulin signalling requires glucose to promote lipid anabolism in adipocytes

scientific article published on 28 July 2020

Integrating adipocyte insulin signaling and metabolism in the multi-omics era

scientific article published in 2022

Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes

scientific article

Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway

scientific article

Lactate production is a prioritized feature of adipocyte metabolism

scientific article published on 05 November 2019

Lipid and glucose metabolism in hepatocyte cell lines and primary mouse hepatocytes: a comprehensive resource for in vitro studies of hepatic metabolism

scientific article published on 29 January 2019

Mapping insulin/GLUT4 circuitry.

scientific article published on 15 March 2011

Membrane Topology of Trafficking Regulator of GLUT4 1 (TRARG1)

scientific article published on 07 June 2018

Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance.

scientific article

Mitochondrial oxidants, but not respiration, are sensitive to glucose in adipocytes

scientific article published on 19 November 2019

Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation

scientific article published on 29 March 2018

Muscle and adipose tissue insulin resistance: malady without mechanism?

scientific article published on 27 July 2018

Muscling in on GLUT4 kinetics.

scientific article published on May 2010

Novel systems for dynamically assessing insulin action in live cells reveals heterogeneity in the insulin response.

scientific article published on 18 January 2013

Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle

scientific article

Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes

scientific article

Re-fraction: a machine learning approach for deterministic identification of protein homologues and splice variants in large-scale MS-based proteomics

scientific article published on 30 March 2012

Selective insulin resistance in adipocytes

scientific article published on 26 February 2015

Serine 474 phosphorylation is essential for maximal Akt2 kinase activity in adipocytes

scientific article published on 22 September 2019

Systemic VEGF-A Neutralization Ameliorates Diet-Induced Metabolic Dysfunction

scientific article published on 02 April 2014

Terminal Galactosylation and Sialylation Switching on Membrane Glycoproteins upon TNF-Alpha-Induced Insulin Resistance in Adipocytes

scientific article published on 4 November 2015

The RabGAP TBC1D1 plays a central role in exercise-regulated glucose metabolism in skeletal muscle.

scientific article published on 9 January 2015

The amino acid transporter, SLC1A3, is plasma membrane-localised in adipocytes and its activity is insensitive to insulin

scientific article published on 29 December 2016

The role of the Niemann-Pick disease, type C1 protein in adipocyte insulin action.

scientific article

The transcriptional response to oxidative stress is part of, but not sufficient for, insulin resistance in adipocytes

scientific article published on 29 January 2018

Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies

scientific article

mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes.

scientific article published in September 2016

mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3

scientific article published on 22 June 2016

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