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List of works by Johan Jakobsson

A new approach for ratiometric in vivo calcium imaging of microglia.

scientific article published on 20 July 2017

Activation of endogenous retroviruses during brain development causes an inflammatory response

scientific article published on 01 March 2021

Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

scientific article published on 18 July 2019

Applications of lentiviral vectors for biology and gene therapy of neurological disorders.

scientific article

Chemogenetic stimulation of striatal projection neurons modulates responses to Parkinson's disease therapy.

scientific article

Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis

scientific article published on 03 October 2018

Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor.

scientific article

Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?

scientific article published on 28 September 2017

Direct conversion of human fibroblasts to dopaminergic neurons ⬇️

scientific article

Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors.

scientific article

Distinct cognitive effects and underlying transcriptome changes upon inhibition of individual miRNAs in hippocampal neurons.

scientific article published on 27 January 2016

Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness

scientific article published on 01 August 2019

Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator.

scientific article published on August 2004

Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors.

scientific article published on 2 March 2006

Evidence for disease-regulated transgene expression in the brain with use of lentiviral vectors

scientific article published in July 2006

Functional Studies of microRNAs in Neural Stem Cells: Problems and Perspectives ⬇️

scientific article published on February 7, 2012

Generation of induced neurons via direct conversion in vivo

scientific article

Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation

scientific article published on 01 August 2018

Identification of the miRNA targetome in hippocampal neurons using RIP-seq

scientific article published on 28 July 2015

Identifying miRNA Targets Using AGO-RIPseq

scientific article published in January 2018

Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease

scientific article published on 06 May 2020

In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions

scientific article published on November 2011

Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants

scientific article

KAP1 controls endogenous retroviruses in embryonic stem cells

scientific article published in January 2010

KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress.

scientific article

LINE-2 transposable elements are a source of functional human microRNAs and target sites

scientific article published on 13 March 2019

Lentiviral vectors for use in the central nervous system.

scientific article

Lesion-dependent regulation of transgene expression in the rat brain using a human glial fibrillary acidic protein-lentiviral vector

scientific article published in February 2004

Lineage reprogramming: a shortcut to generating functional neurons from fibroblasts.

scientific article published in October 2011

MicroRNA-124 is a subventricular zone neuronal fate determinant.

scientific article published on June 2012

MicroRNAs as Neuronal Fate Determinants.

scientific article published on 22 July 2013

Modulation of epileptogenesis: A paradigm for the integration of enzyme-based microelectrode arrays and optogenetics

scientific article published on 26 November 2019

Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons

scientific article published on 21 May 2015

Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells

scientific article published on 31 December 2019

Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice

scientific article published on 21 December 2015

REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways

scientific article

TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity

scientific article published on 22 April 2013

TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells

scientific article

TRIM28 and the control of transposable elements in the brain.

scientific article published on 6 March 2018

TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells.

scientific article published on 24 December 2014

Targeted transgene expression in rat brain using lentiviral vectors.

scientific article published on September 2003

The Kruppel-associated box repressor domain can trigger de novo promoter methylation during mouse early embryogenesis

scientific article published on 24 September 2007

Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors

scientific article

Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9.

scientific article published in January 2013

let-7 regulates radial migration of new-born neurons through positive regulation of autophagy.

scientific article published on 23 March 2017

miRNAs in brain development

scientific article published on 04 October 2013

microRNA-125 distinguishes developmentally generated and adult-born olfactory bulb interneurons

scientific article published on 05 March 2014

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