Search filters

List of works by Daniel B. Constam

Asymmetric Nodal expression in the mouse is governed by the combinatorial activities of two distinct regulatory elements

scientific article published in November 2004

Automated design of ligands to polypharmacological profiles.

scientific article

Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow.

scientific article

Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis

scientific article published on 01 March 2015

Bicc1 Polymerization Regulates the Localization and Silencing of Bound mRNA.

scientific article published on 27 July 2015

Bicc1 links the regulation of cAMP signaling in polycystic kidneys to microRNA-induced gene silencing.

scientific article published on 28 May 2012

Cellular heterogeneity during embryonic stem cell differentiation to epiblast stem cells is revealed by the ShcD/RaLP adaptor protein

scientific article

Comment on "Human dignity and gene editing"

scientific article published on 29 November 2018

Compartment-Specific Biosensors Reveal a Complementary Subcellular Distribution of Bioactive Furin and PC7.

scientific article published in February 2018

Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6.

scientific article published on 26 December 2017

Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice

scientific article

Epiblast-specific loss of HCF-1 leads to failure in anterior-posterior axis specification

scientific article

Extraembryonic proteases regulate Nodal signalling during gastrulation

scientific journal article

Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex

scientific article published on 01 July 2021

Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10.

scientific article

Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes

scientific article

Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst.

scientific article

KAP1 controls endogenous retroviruses in embryonic stem cells

scientific article published in January 2010

Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment

scientific journal article

Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning

scientific article published on 25 May 2006

Nodal·Gdf1 heterodimers with bound prodomains enable serum-independent nodal signaling and endoderm differentiation.

scientific article

PC7 and the related proteases Furin and Pace4 regulate E-cadherin function during blastocyst formation.

scientific article published on September 2015

Paracrine Activin-A Signaling Promotes Melanoma Growth and Metastasis through Immune Evasion

scientific article published on 24 August 2017

Pathogen-free husbandry conditions alleviate behavioral deficits and neurodegeneration in AD10 anti-NGF mice

scientific article published in January 2014

ProNodal acts via FGFR3 to govern duration of Shh expression in the prechordal mesoderm

scientific article

Regulation of TGFβ and related signals by precursor processing.

scientific article

Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.

scientific article

Riding shotgun: a dual role for the epidermal growth factor-Cripto/FRL-1/Cryptic protein Cripto in Nodal trafficking

scientific article

Role of the RNA-binding protein Bicaudal-C1 and interacting factors in cystic kidney diseases

scientific article published on 12 December 2019

Running the gauntlet: an overview of the modalities of travel employed by the putative morphogen Nodal

scientific article published on 22 July 2009

SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.

scientific article published in July 1996

The microenvironment patterns the pluripotent mouse epiblast through paracrine Furin and Pace4 proteolytic activities.

scientific article

Transforming growth factor-beta 2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression

scientific journal article

Transient production of TGF-beta 2 by postnatal cerebellar neurons and its effect on neuroblast proliferation

scientific article published in May 1994

Urine Fetuin-A is a biomarker of autosomal dominant polycystic kidney disease progression.

scientific article published on 30 March 2015

VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5

scientific article

Paulina is supported by:

About Paulina

Help