List of works - Annemette V. Thougaard

A murine experimental anthracycline extravasation model: pathology and study of the involvement of topoisomerase II alpha and iron in the mechanism of tissue damage

scientific article published on 15 January 2010

A preclinical study on the rescue of normal tissue by nicotinic acid in high-dose treatment with APO866, a specific nicotinamide phosphoribosyltransferase inhibitor.

scientific article

Combining etoposide and dexrazoxane synergizes with radiotherapy and improves survival in mice with central nervous system tumors

scientific article published in September 2005

Determination of serum tetranectin: technical and clinical evaluation of three sandwich immunoassays

scientific article published on 01 August 1998

Dexrazoxane protects against myelosuppression from the DNA cleavage-enhancing drugs etoposide and daunorubicin but not doxorubicin

scientific article

Evaluation of an automated spectrophotometric assay for the determination of total sialic acid in canine serum

scientific article published on 01 January 1994

Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy

scientific article

Exploratory toxicology as an integrated part of drug discovery. Part I: Why and how.

scientific article published on 22 December 2013

Exploratory toxicology as an integrated part of drug discovery. Part II: Screening strategies.

scientific article published on 25 December 2013

High-content analysis/screening for predictive toxicology: application to hepatotoxicity and genotoxicity.

scientific article published on 21 February 2014

Linking HSP90 target occupancy to HSP70 induction and efficacy in mouse brain.

scientific article published on 27 December 2015

Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-activity relationship

scientific article published on 13 November 2013

Substituted purine analogues define a novel structural class of catalytic topoisomerase II inhibitors

scientific article published in August 2005

Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase.

scientific article

Tetranectin in cerebrospinal fluid of patients with multiple sclerosis.

scientific article published in January 2006

Tetranectin in cerebrospinal fluid: biochemical characterisation and evidence of intrathecal synthesis or selective uptake into CSF

scientific article

Tetranectin-like protein in vertebrate serum: a comparative immunochemical analysis

scientific article published on 01 April 2001

The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies

scientific article published on 5 February 2009

The histone deacetylase inhibitor PXD101 synergises with 5-fluorouracil to inhibit colon cancer cell growth in vitro and in vivo.

scientific article published on 24 November 2006

Treatment of experimental extravasation of amrubicin, liposomal doxorubicin, and mitoxantrone with dexrazoxane

scientific article published on 6 December 2011

VETSTAT-the Danish system for surveillance of the veterinary use of drugs for production animals.

scientific article published in March 2003

Validation of a high throughput flow cytometric in vitro micronucleus assay including assessment of metabolic activation in TK6 cells

scientific article published on 11 August 2014

List of works by Annemette V. Thougaard

A murine experimental anthracycline extravasation model: pathology and study of the involvement of topoisomerase II alpha and iron in the mechanism of tissue damage

A preclinical study on the rescue of normal tissue by nicotinic acid in high-dose treatment with APO866, a specific nicotinamide phosphoribosyltransferase inhibitor.

Combining etoposide and dexrazoxane synergizes with radiotherapy and improves survival in mice with central nervous system tumors

Determination of serum tetranectin: technical and clinical evaluation of three sandwich immunoassays

Dexrazoxane protects against myelosuppression from the DNA cleavage-enhancing drugs etoposide and daunorubicin but not doxorubicin

Evaluation of an automated spectrophotometric assay for the determination of total sialic acid in canine serum

Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy

Exploratory toxicology as an integrated part of drug discovery. Part I: Why and how.

Exploratory toxicology as an integrated part of drug discovery. Part II: Screening strategies.

High-content analysis/screening for predictive toxicology: application to hepatotoxicity and genotoxicity.

Linking HSP90 target occupancy to HSP70 induction and efficacy in mouse brain.

Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-activity relationship

Substituted purine analogues define a novel structural class of catalytic topoisomerase II inhibitors

Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase.

Tetranectin in cerebrospinal fluid of patients with multiple sclerosis.

Tetranectin in cerebrospinal fluid: biochemical characterisation and evidence of intrathecal synthesis or selective uptake into CSF

Tetranectin-like protein in vertebrate serum: a comparative immunochemical analysis

The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies

The histone deacetylase inhibitor PXD101 synergises with 5-fluorouracil to inhibit colon cancer cell growth in vitro and in vivo.

Treatment of experimental extravasation of amrubicin, liposomal doxorubicin, and mitoxantrone with dexrazoxane

VETSTAT-the Danish system for surveillance of the veterinary use of drugs for production animals.

Validation of a high throughput flow cytometric in vitro micronucleus assay including assessment of metabolic activation in TK6 cells