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List of works by Carlos Pirola

A Rare Nonsense Mutation in the Glucokinase Regulator Gene Is Associated With a Rapidly Progressive Clinical Form of Nonalcoholic Steatohepatitis

article

A decreased mitochondrial DNA content is related to insulin resistance in adolescents

scientific article published on 24 April 2008

A diagnostic model to differentiate simple steatosis from nonalcoholic steatohepatitis based on the likelihood ratio form of Bayes theorem

scientific article published on 28 November 2008

A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity.

scientific article published on October 2009

A1166C angiotensin II type 1 receptor gene polymorphism may predict hemodynamic response to losartan in patients with cirrhosis and portal hypertension

scientific article published in March 2005

Alanine and aspartate aminotransferase and glutamine-cycling pathway: their roles in pathogenesis of metabolic syndrome

scientific article

Angiotensin II enhances long-term memory in the crab Chasmagnathus

scientific article published in January 1996

Angiotensin-(1-7) through AT receptors mediates tyrosine hydroxylase degradation via the ubiquitin-proteasome pathway

scientific article published on 22 January 2009

Association between diencephalic thyroliberin and arterial blood pressure in agouti-yellow and ob/ob mice may be mediated by leptin.

scientific article published on October 2007

Association of the C-344T aldosterone synthase gene variant with essential hypertension: a meta-analysis.

scientific article published on January 2007

Association of the multidrug-resistance-associated protein gene (ABCC2) variants with intrahepatic cholestasis of pregnancy

scientific article published on 23 October 2007

Brain amines in glucocorticoid-induced hypertension in the rat.

scientific article published in February 1992

Cardiac thyrotropin-releasing hormone mediates left ventricular hypertrophy in spontaneously hypertensive rats.

scientific article

Cardiovascular disease is associated with high-fat-diet-induced liver damage and up-regulation of the hepatic expression of hypoxia-inducible factor 1α in a rat model

scientific article

Cardiovascular phenotype of nonalcoholic fatty liver disease: hanging the paradigm about the role of distant toxic fat accumulation on vascular disease

scientific article published on 01 September 2012

Cholinergic hyperactivity in the lateral septal area of spontaneously hypertensive rats: depressor effect of hemicholinium-3 and pirenzepine

scientific article published in April 1991

Circulating MicroRNA-122 signature in nonalcoholic fatty liver disease and cardiovascular disease: a new endocrine system in metabolic syndrome

scientific article published on 06 March 2013

Circulating levels and hepatic expression of molecular mediators of atherosclerosis in nonalcoholic fatty liver disease

scientific article published on 13 October 2009

Clinical features of the metabolic syndrome in adolescents: minor role of the Trp64Arg beta3-adrenergic receptor gene variant

scientific article

Contribution of the functional 5-HTTLPR variant of the SLC6A4 gene to obesity risk in male adults

scientific article published in February 2008

Cyclooxygenase inhibition Up-regulates liver carnitine palmitoyltransferase 1A expression and improves fatty liver

scientific article published on 01 June 2011

DNA methylation and hepatic insulin resistance and steatosis

scientific article published on July 2012

Editorial: surviving your genes-the role of PNPLA3 variation in end-stage liver disease

scientific article published on 01 October 2018

Effects of rotating shift work on biomarkers of metabolic syndrome and inflammation.

scientific article published in March 2007

Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease

scientific article

Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: impact of liver methylation of the peroxisome proliferator-activated receptor γ coactivator 1α promoter.

scientific article published on October 2010

Epigenetics factors in nonalcoholic fatty liver disease

scientific article published on 01 June 2020

Epigenetics of insulin resistance: an emerging field in translational medicine

scientific article published on April 2013

Fetal metabolic programming and epigenetic modifications: a systems biology approach ⬇️

scientific article published on January 11, 2013

Gene prioritization based on biological plausibility over genome wide association studies renders new loci associated with type 2 diabetes

scientific article

Genetic Variation in the FAAH Gene and Metabolic Syndrome–related Phenotypes

article

Genetic determinants of acquired cholestasis: a systems biology approach

scientific article published on January 2012

Genetic variants in STAT3 are associated with nonalcoholic fatty liver disease

scientific article published on 11 September 2008

Genetics of the cardiometabolic syndrome: new insights and therapeutic implications.

scientific article published on October 2007

High fat diet-induced liver steatosis promotes an increase in liver mitochondrial biogenesis in response to hypoxia

scientific article

Hyperhomocysteinemia but not MTHFR genotype is associated with young-onset essential hypertension.

scientific article published in May 2003

Increase in muscarinic receptors in rat intestine by Thyrotropin Releasing Hormone (TRH)

scientific article published on 01 April 1984

Increased levels of resistin in rotating shift workers: A potential mediator of cardiovascular risk associated with circadian misalignment

scientific article published on 04 January 2010

Influence of hepatocyte nuclear factor 4alpha (HNF4alpha) gene variants on the risk of type 2 diabetes: a meta-analysis in 49,577 individuals

scientific article published on 01 January 2010

Integrative study of hypothalamus-pituitary-thyroid-immune system interaction: thyroid hormone-mediated modulation of lymphocyte activity through the protein kinase C signaling pathway

scientific article

Intrahepatic bacterial metataxonomic signature in non-alcoholic fatty liver disease

scientific article published on 02 January 2020

Knocking down the diencephalic thyrotropin-releasing hormone precursor gene normalizes obesity-induced hypertension in the rat.

scientific article published on 16 January 2007

Letter by Landa et al regarding article, "Protein tyrosine phosphatase 1B, a major regulator of leptin-mediated control of cardiovascular function".

scientific article published in June 2010

Letter: Mendelian randomisation to investigate moderate alcohol consumption in nonalcoholic fatty liver disease; modest effects need large numbers-authors' reply

scientific article published in August 2017

Liver transcriptional profile of atherosclerosis-related genes in human nonalcoholic fatty liver disease.

scientific article published on 18 May 2011

Loci From a Genome-Wide Analysis of Bilirubin Levels Are Associated With Gallstone Risk and Composition

article

Losartan reduces liver expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced rat nonalcoholic fatty liver disease model

scientific article published on 29 January 2009

Low Mpl receptor expression in a pedigree with familial platelet disorder with predisposition to acute myelogenous leukemia and a novel AML1 mutation

scientific article

Maternal high-fat intake during pregnancy programs metabolic-syndrome-related phenotypes through liver mitochondrial DNA copy number and transcriptional activity of liver PPARGC1A.

scientific article published on 30 May 2012

Maternal pregestational BMI is associated with methylation of the PPARGC1A promoter in newborns.

scientific article

Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease ⬇️

scientific article published on May 14, 2011

Metabolic syndrome: from the genetics to the pathophysiology

scientific article published on April 2011

Metastasis-associated lung adenocarcinoma transcript 1 as a common molecular driver in the pathogenesis of nonalcoholic steatohepatitis and chronic immune-mediated liver damage.

scientific article

Methylation of TFAM gene promoter in peripheral white blood cells is associated with insulin resistance in adolescents

scientific article published on 12 February 2010

Mitochondrial DNA copy number is modulated by genetic variation in the signal transducer and activator of transcription 3 (STAT3).

scientific article

Mitochondrial DNA depletion in small- and large-for-gestational-age newborns.

scientific article

NAFLD and cardiometabolic risk factors: The liver fibrosis trajectory through the lens of biological interactions

scientific article published on 06 December 2020

Non-alcoholic fatty liver disease is strongly associated with carotid atherosclerosis: a systematic review

scientific article published on 02 July 2008

Normal platelets possess the soluble form of IL-6 receptor

scientific article

Obstructive sleep apnea is associated with fatty liver and abnormal liver enzymes: a meta-analysis

scientific article

Odor perception between heterosexual partners: its association with depression, anxiety, and genetic variation in odorant receptor OR7D4.

scientific article published on 18 November 2010

PDGF-A, PDGF-B, TGFbeta, and bFGF mRNA levels in patients with essential thrombocythemia treated with anagrelide

scientific article

PNPLA3, the triacylglycerol synthesis/hydrolysis/storage dilemma, and nonalcoholic fatty liver disease

scientific article

Parathyroid hormone-related protein expression in vascular smooth muscle of spontaneously hypertensive rats: evidence for lack of response to angiotensin II

scientific article published on 01 October 1998

Parathyroid hormone-related protein overexpression decreases blood pressure in spontaneously hypertensive rats

scientific article

Peroxisome proliferator-activated receptor gamma and its coactivator-1 alpha may be associated with features of the metabolic syndrome in adolescents

scientific article published on 01 October 2005

Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease

scientific article published on 15 October 2008

Renin-angiotensin-aldosterone system loci and multilocus interactions in young-onset essential hypertension.

scientific article

Review article: shared disease mechanisms between non-alcoholic fatty liver disease and metabolic syndrome - translating knowledge from systems biology to the bedside

scientific article published on 04 February 2019

Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy.

scientific article published in April 2008

Role of genetic variation in insulin-like growth factor 1 receptor on insulin resistance and arterial hypertension

scientific article published in June 2010

Role of the C-344T aldosterone synthase gene variant in left ventricular mass and left ventricular structure-related phenotypes.

scientific article published on 13 August 2007

Serotonergic and noradrenergic mechanisms involved in the cardiovascular effects of angiotensin II injected into the anterior hypothalamic preoptic region of rats

scientific article published on 01 January 1981

Serotonin and serotonin transporter gene variant in rotating shift workers.

scientific article published on August 2007

Serum aminotransferases in nonalcoholic fatty liver disease are a signature of liver metabolic perturbations at the amino acid and Krebs cycle level

scientific article published on 20 January 2016

Shift work and subclinical atherosclerosis: recommendations for fatty liver disease detection

scientific article published on 17 June 2009

Short allele of serotonin transporter gene promoter is a risk factor for obesity in adolescents

scientific article published on 01 February 2007

Should Nonalcoholic Fatty Liver Disease Be Included in the Definition of Metabolic Syndrome? A Cross-Sectional Comparison With Adult Treatment Panel III Criteria in Nonobese Nondiabetic Subjects: Response to Musso et al

scientific article published on 01 May 2008

SiRNA-mediated silencing of the diencephalic thyrotropin-releasing hormone precursor gene decreases the arterial blood pressure in the obese agouti mice

scientific article

Splice variant rs72613567 prevents worst histologic outcomes in patients with nonalcoholic fatty liver disease

scientific article published on 15 October 2018

Study of genetic variation in the STAT3 on obesity and insulin resistance in male adults.

scientific article published on 24 April 2008

Systematic review with meta-analysis: risk factors for non-alcoholic fatty liver disease suggest a shared altered metabolic and cardiovascular profile between lean and obese patients

scientific article (publication date: 2 May 2017)

Systematic review with meta-analysis: the significance of histological disease severity in lean patients with nonalcoholic fatty liver disease

scientific article

Systems biology elucidates common pathogenic mechanisms between nonalcoholic and alcoholic-fatty liver disease

scientific article

Targeting the renin-angiotensin system: potential beneficial effects of the angiotensin II receptor blockers in patients with nonalcoholic steatohepatitis

scientific article published on 01 December 2011

The Association between High Fat Diet around Gestation and Metabolic Syndrome-related Phenotypes in Rats: A Systematic Review and Meta-Analysis.

scientific article

The G-308A promoter variant of the tumor necrosis factor-alpha gene is associated with hypertension in adolescents harboring the metabolic syndrome

scientific article

The cholinergic system participates in thyrotropin-releasing hormone (TRH) regulation

scientific article published in February 1992

The impact of maternal high-fat feeding on liver and abdominal fat accumulation in adult offspring under a long-term high-fat diet

scientific article published on 01 June 2010

The influence of common gene variants of the xenobiotic receptor (PXR) in genetic susceptibility to intrahepatic cholestasis of pregnancy

scientific article published on 3 December 2009

The nonalcoholic steatohepatitis metabotype: Imbalance of circulating amino acids and transamination reactions reflect impaired mitochondrial function

scientific article

The nuclear receptor PXR gene variants are associated with liver injury in nonalcoholic fatty liver disease

scientific article published in January 2010

Thyrotropin-releasing hormone decreases leptin and mediates the leptin-induced pressor effect

scientific article published on 01 February 2002

Thyrotropin-releasing hormone in cardiovascular pathophysiology

scientific article

Thyrotropin-releasing hormone increases the number of muscarinic receptors in the lateral septal area of the rat brain

scientific article published in August 1983

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