List of works by Luca Grumolato

A new piece to the unsolved planar cell polarity puzzle

scientific article

Abelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylation

scientific journal article

CRISPR-Barcoding for Intratumor Genetic Heterogeneity Modeling and Functional Analysis of Oncogenic Driver Mutations.

scientific article published on 19 July 2016

CRISPR/Cas9 editing of the genome for cancer modeling

scientific article published on 10 March 2017

Canonical Wnts function as potent regulators of osteogenesis by human mesenchymal stem cells

scientific article

Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors.

scientific article

Chromatin modifications sequentially enhance ErbB2 expression in ErbB2-positive breast cancers

scientific article published on 10 October 2013

Circulating EM66 is a highly sensitive marker for the diagnosis and follow-up of pheochromocytoma.

scientific article

Diverse mechanisms of Wnt activation and effects of pathway inhibition on proliferation of human gastric carcinoma cells

scientific article

High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene, CDC25A.

scientific article

Identification of potential gene markers and insights into the pathophysiology of pheochromocytoma malignancy

scientific article published on 18 September 2007

Identification of the secretogranin II-derived peptide EM66 in pheochromocytomas as a potential marker for discriminating benign versus malignant tumors.

scientific article

Maternal perinatal undernutrition alters neuronal and neuroendocrine differentiation in the rat adrenal medulla at weaning

scientific journal article

Maternal perinatal undernutrition has long-term consequences on morphology, function and gene expression of the adrenal medulla in the adult male rat.

scientific article published in August 2011

Microarray and suppression subtractive hybridization analyses of gene expression in pheochromocytoma cells reveal pleiotropic effects of pituitary adenylate cyclase-activating polypeptide on cell proliferation, survival, and adhesion.

scientific article published in June 2003

Modeling intratumor heterogeneity through CRISPR-barcodes

scientific article published on 6 September 2016

Molecular characterization of frog chromogranin B reveals conservation of selective sequences encoding potential novel regulatory peptides

scientific article published in January 2002

Novel splice variants of type I pituitary adenylate cyclase-activating polypeptide receptor in frog exhibit altered adenylate cyclase stimulation and differential relative abundance

scientific article

PACAP and NGF regulate common and distinct traits of the sympathoadrenal lineage: effects on electrical properties, gene markers and transcription factors in differentiating PC12 cells

scientific article published in January 2003

Pituitary adenylate cyclase--activating polypeptide stimulates secretoneurin release and secretogranin II gene transcription in bovine adrenochromaffin cells

scientific article published in October 2002

Pituitary adenylate cyclase-activating polypeptide (PACAP) promotes both survival and neuritogenesis in PC12 cells through activation of nuclear factor κB (NF-κB) pathway: involvement of extracellular signal-regulated kinase (ERK), calcium, and c-RE

scientific article published on 5 April 2013

Pituitary adenylate cyclase-activating polypeptide regulates neuroendocrine markers and transcription factors in differentiating pheochromocytoma cells

scientific article published in October 2002

Proinflammatory cytokines TNF-alpha and IL-1alpha stimulate neuropeptide gene expression in adrenochromaffin cells

scientific article published on 01 October 2002

ROR1 contributes to melanoma cell growth and migration by regulating N-cadherin expression via the PI3K/Akt pathway.

scientific article published on 28 October 2015

Role of PACAP in the physiology and pathology of the sympathoadrenal system.

scientific article published on 22 October 2007

Selenoprotein T is a PACAP-regulated gene involved in intracellular Ca2+ mobilization and neuroendocrine secretion

scientific article

Selenoprotein T is a novel OST subunit that regulates UPR signaling and hormone secretion

scientific article published on 19 September 2017

Tolerant/Persister Cancer Cells and the Path to Resistance to Targeted Therapy

scientific article published on 04 December 2020

XPO1E571K Mutation Modifies Exportin 1 Localisation and Interactome in B-cell Lymphoma

scientific article published on 30 September 2020

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