Search filters

List of works by Simon Hughes

Acridine mutagenesis of zebrafish (Danio rerio).

scientific article

Aging-related satellite cell differentiation defect occurs prematurely after Ski-induced muscle hypertrophy

scientific article published in October 2002

An inducer protein may control the timing of fate switching in a bipotential glial progenitor cell in rat optic nerve

scientific article published on 01 September 1987

Anaesthetic tricaine acts preferentially on neural voltage-gated sodium channels and fails to block directly evoked muscle contraction

scientific article

Analyses of the differentiation potential of satellite cells from myoD-/-, mdx, and PMP22 C22 mice.

scientific article

Are guanine nucleotide binding proteins a distinct class of regulatory proteins? ⬇️

scientific article published on November 28, 1983

CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function

scientific article published on 17 August 2017

Cdkn1c drives muscle differentiation through a positive feedback loop with Myod.

scientific article

Cellular dynamics of regeneration reveals role of two distinct Pax7 stem cell populations in larval zebrafish muscle repair

scientific article published on 05 May 2016

Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture

scientific article published in September 1988

Circadian regulation of muscle growth independent of locomotor activity

scientific article published on 23 November 2020

Comparison of neurolin (ALCAM) and neurolin-like cell adhesion molecule (NLCAM) expression in zebrafish

scientific article

Cooperation between Shh and IGF‐I in promoting myogenic proliferation and differentiation via the MAPK/ERK and PI3K/Akt pathways requires smo activity ⬇️

scientific article published on April 1, 2012

Defective cranial skeletal development, larval lethality and haploinsufficiency in Myod mutant zebrafish.

scientific article

Development of mandibular, hyoid and hypobranchial muscles in the zebrafish: homologies and evolution of these muscles within bony fishes and tetrapods

scientific article (publication date: 28 February 2008)

Differential requirements for myogenic regulatory factors distinguish medial and lateral somitic, cranial and fin muscle fibre populations

scientific article published on February 2009

Distinct functions of alternatively spliced isoforms encoded by zebrafish mef2ca and mef2cb

scientific article

Dystrobrevin and dystrophin family gene expression in zebrafish

scientific article published on 24 October 2007

EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype

scientific article published on 25 June 2019

Evidence for differential post-translational modifications of slow myosin heavy chain during murine skeletal muscle development

scientific article published in February 2000

Evidence that satellite cell decrement contributes to preferential decline in nuclear number from large fibres during murine age-related muscle atrophy

scientific article published on 01 October 2005

Extrinsic influences on limb muscle organisation.

scientific article

Fast myosin heavy chains expressed in secondary mammalian muscle fibers at the time of their inception.

scientific article published on September 1994

Fetal myoblast clones contribute to both fast and slow fibres in developing rat muscle.

scientific article published in March 1999

Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis

scientific article published on 28 April 2020

Fgf8 drives myogenic progression of a novel lateral fast muscle fibre population in zebrafish.

scientific article published on 24 August 2005

Hedgehog can drive terminal differentiation of amniote slow skeletal muscle

scientific article

Hedgehog regulation of superficial slow muscle fibres in Xenopus and the evolution of tetrapod trunk myogenesis

scientific article published on 16 June 2004

Hedgehog signalling is required for maintenance of myf5 and myoD expression and timely terminal differentiation in zebrafish adaxial myogenesis

scientific article published in August 2001

Intermediate filament-co-localized molecules with myosin heavy chain epitopes define distinct cellular domains in hair follicles and epidermis

scientific article

Light changes the membrane potential and ion balances of retinal rod disks

scientific article published on 01 March 1985

Local signals in the chick limb bud can override myoblast lineage commitment: induction of slow myosin heavy chain in fast myoblasts

scientific article published in July 1999

Maternal Larp6 controls oocyte development, chorion formation and elevation

scientific article published on 26 February 2020

Mef2s are required for thick filament formation in nascent muscle fibres.

scientific article published on 30 May 2007

Modulation of MHC class II antigen expression in human myoblasts after treatment with IFN-gamma

scientific article published on 01 July 1991

Mrf4 (myf6) is dynamically expressed in differentiated zebrafish skeletal muscle.

scientific article published on 15 June 2007

Muscle development: electrical control of gene expression

scientific article published in December 1998

Muscle development: reversal of the differentiated state.

scientific article

Muscle hypertrophy induced by the Ski protein: cyto-architecture and ultrastructure

scientific article published in October 2005

Muscular expressions: profiling genes in complex tissues

scientific article

MyoD- and nerve-dependent maintenance of MyoD expression in mature muscle fibres acts through the DRR/PRR element

scientific article

Myogenin induces a shift of enzyme activity from glycolytic to oxidative metabolism in muscles of transgenic mice

scientific journal article

Myogenin is an essential regulator of adult myofibre growth and muscle stem cell homeostasis

scientific article published on 01 October 2020

Myogenin promotes myocyte fusion to balance fibre number and size

scientific article published in Nature Communications

Myotome adaptability confers developmental robustness to somitic myogenesis in response to fibre number alteration.

scientific article published on 5 September 2017

Nerve-dependent changes in skeletal muscle myosin heavy chain after experimental denervation and cross-reinnervation and in a demyelinating mouse model of Charcot-Marie-Tooth disease type 1A.

scientific article

Notch signalling is required for the formation of structurally stable muscle fibres in zebrafish

scientific article

Notochord induction of zebrafish slow muscle mediated by Sonic hedgehog.

scientific article published on September 1997

Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion

scientific article published in October 2013

Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion.

scientific article

Retroviral lineage markers for assessing myoblast fate in vivo

scientific article published on 01 January 1990

Running out of control

scientific article published in Nature

Running without regulators

scientific article published in Nature

Selective accumulation of MyoD and myogenin mRNAs in fast and slow adult skeletal muscle is controlled by innervation and hormones

scientific article published on 01 August 1993

Sequential actions of Pax3 and Pax7 drive xanthophore development in zebrafish neural crest

scientific article

Signals and myogenic regulatory factors restrict pax3 and pax7 expression to dermomyotome-like tissue in zebrafish.

scientific article

Size changes of phosphodiesterase in bovine rod outer segments on illumination

scientific article published in March 1983

Sonic hedgehog acts cell-autonomously on muscle precursor cells to generate limb muscle diversity

scientific article

Target size analysis of rhodopsin in retinal rod disk membranes.

scientific article

The Cannabinoid Receptor Interacting Proteins 1 of zebrafish are not required for morphological development, viability or fertility.

scientific article published on 7 July 2017

The dystrotelin, dystrophin and dystrobrevin superfamily: new paralogues and old isoforms.

scientific article

The kinase domain of titin controls muscle gene expression and protein turnover

scientific article

The role of hedgehog proteins in vertebrate slow and fast skeletal muscle patterning

scientific article published in July 1998

Three slow myosin heavy chains sequentially expressed in developing mammalian skeletal muscle.

scientific article published on July 1993

Thyroid hormone effects on contractility and myosin composition of soleus muscle and single fibres from young and old rats

scientific article published on 01 July 1996

Type-2 astrocyte development in rat brain cultures is initiated by a CNTF like protein produced by type-1 astrocytes

scientific article published on 01 August 1988

Urokinase-dependent plasminogen activation is required for efficient skeletal muscle regeneration in vivo

scientific article published on 01 March 2001

Vestigial-like-2b (VITO-1b) and Tead-3a (Tef-5a) expression in zebrafish skeletal muscle, brain and notochord

scientific article

WNT-3, Expressed by Motoneurons, Regulates Terminal Arborization of Neurotrophin-3-Responsive Spinal Sensory Neurons

scientific article published on 01 September 2002

Wnt signaling promotes AChR aggregation at the neuromuscular synapse in collaboration with agrin

scientific journal article

Zebrafish Mef2ca and Mef2cb are essential for both first and second heart field cardiomyocyte differentiation.

scientific article published on 28 June 2012

eIF4EBP3L acts as a gatekeeper of TORC1 in activity-dependent muscle growth by specifically regulating Mef2ca translational initiation.

scientific article

n beta geo, a combined selection and reporter gene for retroviral and transgenic studies.

scientific article published on October 1997

Paulina is supported by:

About Paulina

Help