List of works by Keith Fowke

3,28-Di-O-(dimethylsuccinyl)-betulin isomers as anti-HIV agents.

scientific article

A common CD4 gene variant is associated with an increased risk of HIV-1 infection in Kenyan female commercial sex workers

scientific article published in May 2009

A distinct cytokine and chemokine profile at the genital mucosa is associated with HIV-1 protection among HIV-exposed seronegative commercial sex workers

article

A naturally occurring Vif mutant (I107T) attenuates anti-APOBEC3G activity and HIV-1 replication

scientific article published on 23 May 2013

Age and menopause affect the expression of specific cytokines/chemokines in plasma and cervical lavage samples from female sex workers in Nairobi, Kenya

scientific article published on 22 October 2013

Antigen-specific gene expression profiles of peripheral blood mononuclear cells do not reflect those of T-lymphocyte subsets

scientific article published on September 2004

Apoptosis: a method for evaluating the cryopreservation of whole blood and peripheral blood mononuclear cells

scientific article published in October 2000

Association of high-risk sexual behaviour with diversity of the vaginal microbiota and abundance of Lactobacillus

scientific article

Association of sex work with reduced activation of the mucosal immune system

scientific article published on 12 January 2014

Bacterial vaginosis, HIV serostatus and T-cell subset distribution in a cohort of East African commercial sex workers: retrospective analysis

scientific article

C868T single nucleotide polymorphism and HIV type 1 disease progression among postpartum women in Kenya

scientific article

CD161 identifies polyfunctional Th1/Th17 cells in the genital mucosa that are depleted in HIV-infected female sex workers from Nairobi, Kenya

scientific article published on 11 September 2017

CD4+ T cell responses in HIV-exposed seronegative women are qualitatively distinct from those in HIV-infected women

scientific article published in December 2004

CYFIP2 is highly abundant in CD4+ cells from multiple sclerosis patients and is involved in T cell adhesion

scientific article

Cellular immune responses to recurring influenza strains have limited boosting ability and limited cross reactivity to other strains

article

Cellular immune responses to recurring influenza strains have limited boosting ability and limited cross-reactivity to other strains

scientific article published in August 2010

Characterization of CD8 T-cell responses in HIV-1-exposed seronegative commercial sex workers from Nairobi, Kenya

scientific article

Characterization of a trypsin-dependent avian influenza H5N1-pseudotyped HIV vector system for high throughput screening of inhibitory molecules

scientific article published on 06 March 2008

Characterization of anti-HIV activity mediated by R88-APOBEC3G mutant fusion proteins in CD4+ T cells, peripheral blood mononuclear cells, and macrophages

scientific article

Characterization of the Genital Mucosa Immune Profile to Distinguish Phases of the Menstrual Cycle: Implications for HIV Susceptibility

article

Chemokine receptor 5 △32 allele in patients with severe pandemic (H1N1) 2009

scientific article

Chemorepellent Semaphorin 3E Negatively Regulates Neutrophil Migration In Vitro and In Vivo

scientific article published on 2 December 2016

Clade-specific evolution mediated by HLA-B*57/5801 in human immunodeficiency virus type 1 clade A1 p24.

scientific article published on 16 September 2009

Clarifying the role of G protein signaling in HIV infection: new approaches to an old question

scientific article published on July 1, 2010

Cohorts for the study of HIV‐1-exposed but uninfected individuals: benefits and limitations

scientific article

Collection, isolation, and flow cytometric analysis of human endocervical samples

scientific article

Comparison of hemagglutination inhibition and microbead array assays for the measurement of influenza antibody levels in HIV-infected adults

scientific article published on 19 May 2016

Comprehensive proteomic study identifies serpin and cystatin antiproteases as novel correlates of HIV-1 resistance in the cervicovaginal mucosa of female sex workers

scientific article published on 5 October 2011

Construction of an infectious HIV type 1 molecular clone from an African patient with a subtype D/C Recombinant Virus

scientific article published in September 2004

Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear import

scientific article

Cross-Clade CD8+ T-Cell Responses With a Preference for the Predominant Circulating Clade

article

Cytomegalovirus, aging, and HIV: a perfect storm

scientific article published on July 2012

Decreased immune activation in resistance to HIV-1 infection is associated with an elevated frequency of CD4(+)CD25(+)FOXP3(+) regulatory T cells

scientific article published in May 2009

Development of a novel allo-independent HIV-1 virus preparation for use in immunoassays

scientific article published on June 2002

Development of polyether urethane intravaginal rings for the sustained delivery of hydroxychloroquine

scientific article

Elevated T cell counts and RANTES expression in the genital mucosa of HIV-1-resistant Kenyan commercial sex workers

scientific article published on 27 July 2005

Elevated expression of LAG-3, but not PD-1, is associated with impaired iNKT cytokine production during chronic HIV-1 infection and treatment

scientific article

Elevation of immune activation in kenyan women is associated with alterations in immune function: implications for vaccine development

article

Enrichment of LAG-3, but not PD-1, on double negative T cells at the female genital tract

scientific article

Epitope cross-reactivity frequently differs between central and effector memory HIV-specific CD8+ T cells.

scientific article published in March 2007

Epitope mapping of HIV-specific CD8+ T cells in a cohort dominated by clade A1 infection

scientific article

Estimated cumulative incidence of pandemic (H1N1) influenza among pregnant women during the first wave of the 2009 pandemic

scientific article

Evaluation of influenza-specific humoral response by microbead array analysis

scientific article

Free radical scavenging activity and immunomodulatory effect of Stachytarpheta angustifolia leaf extract

article

Free radical scavenging activity, phenolic contents and cytotoxicity of selected Nigerian medicinal plants

article

HIV Controllers Are Distinguished by Chemokine Expression Profile and HIV-Specific T-Cell Proliferative Potential

article

HIV viral set point and host immune control in individuals with HIV-specific CD8+ T-cell responses prior to HIV acquisition

scientific article published in June 2010

HIV-1 Env-specific cytotoxic T-lymphocyte responses in exposed, uninfected Kenyan sex workers: a prospective analysis

scientific article published in October 2004

HIV-1-specific cellular immune responses among HIV-1-resistant sex workers

scientific article published in December 2000

HIV-specific CD8+ T-cell proliferation is prospectively associated with delayed disease progression.

scientific article

HIV-specific immunity following immunization with HIV synthetic envelope peptides in asymptomatic HIV-infected patients

article

HIV‐exposed seronegative commercial sex workers show a quiescent phenotype in the CD4+ T cell compartment and reduced expression of HIV‐dependent host factors

scientific article

High level of soluble HLA-G in the female genital tract of Beninese commercial sex workers is associated with HIV-1 infection

scientific article

Human leucocyte antigen supertypes and immune susceptibility to HIV-1, implications for vaccine design

scientific article

IL-7Ralpha expression on CD4+ T lymphocytes decreases with HIV disease progression and inversely correlates with immune activation

scientific article published in February 2006

Immune quiescence: a model of protection against HIV infection

scientific article

Immunogenetic factors associated with severe respiratory illness caused by zoonotic H1N1 and H5N1 influenza viruses

scientific article

Immunologic and virologic evaluation after influenza vaccination of HIV-1-infected patients

article

Implant delivering hydroxychloroquine attenuates vaginal T lymphocyte activation and inflammation.

scientific article published on 12 March 2018

Improving Adherence to Post-Cervical Biopsy Sexual Abstinence in Kenyan Female Sex Workers

scientific article published on 24 May 2016

In-utero infection with HIV-1 associated with suppressed lymphoproliferative responses at birth.

scientific article published on October 2014

Increased Cervical CD4CCR5 T Cells Among Kenyan Sex Working Women Using Depot Medroxyprogesterone Acetate

scholarly article by Julie Lajoie et al published March 2019 in AIDS Research and Human Retroviruses

Infant CD4 C868T polymorphism is associated with increased human immunodeficiency virus (HIV-1) acquisition

article

Influence of HLA supertypes on susceptibility and resistance to human immunodeficiency virus type 1 infection

scientific article published on 8 May 2000

International symposium on natural immunity to HIV: a gathering of the HIV‐exposed seronegative clan.

scientific article

Invariant NKT cells: regulation and function during viral infection

scientific article

Isolation of rhododaurichromanic acid B and the anti-HIV principles rhododaurichromanic acid A and rhododaurichromenic acid from Rhododendron dauricum

article

Long-term protease inhibitor-containing therapy results in limited improvement in T cell function but not restoration of interleukin-12 production in pediatric patients with AIDS.

scientific article

Loss of CD127 expression links immune activation and CD4(+) T cell loss in HIV infection.

scientific article published on 27 October 2008

Medroxyprogesterone acetate alters the vaginal microbiota and microenvironment in women and increases susceptibility to HIV-1 in humanized mice

scientific article published on 23 October 2019

Microarray analysis of HIV resistant female sex workers reveal a gene expression signature pattern reminiscent of a lowered immune activation state

scientific article

Molecular definition of vaginal microbiota in East African commercial sex workers

scientific article

Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate

scientific article published on 09 May 2022

Mx2 expression is associated with reduced susceptibility to HIV infection in highly exposed HIV seronegative Kenyan sex workers

scientific article published on January 2015

Negative mucosal synergy between Herpes simplex type 2 and HIV in the female genital tract

scientific article published on March 2007

New insights into HIV-1 specific cytotoxic T-lymphocyte responses in exposed, persistently seronegative Kenyan sex workers

scientific article (publication date: November 2001)

P16-35. Specific CD4 responses to HIV-1 epitopes in exposed seronegative (ESN) versus infected commercial sex workers.

scientific article published on 22 October 2009

Preventing HIV infection without targeting the virus: how reducing HIV target cells at the genital tract is a new approach to HIV prevention

scientific article published on 12 September 2017

Reduced cellular susceptibility to in vitro HIV infection is associated with CD4+ T cell quiescence

scientific article

Reduced rates of HIV acquisition during unprotected sex by Kenyan female sex workers predating population declines in HIV prevalence

scientific article published on January 2008

Regular use of depot medroxyprogesterone acetate causes thinning of the superficial lining and apical distribution of HIV target cells in the human ectocervix

scientific article published on 11 August 2020

Resistance to HIV-1 infection among highly exposed sex workers in Nairobi: what mediates protection and why does it develop?

article

Resistance to HIV-1 infection among persistently seronegative prostitutes in Nairobi, Kenya

scientific article

Responses to pandemic ASO3-adjuvanted A/California/07/09 H1N1 influenza vaccine in human immunodeficiency virus-infected individuals

scientific article

Selection, phenotyping and identification of acid and hydrogen peroxide producing bacteria from vaginal samples of Canadian and East African women

scientific article

Serological survey of the novel influenza A H1N1 in inner city Winnipeg, Manitoba, 2009.

scientific article

Short Communication: Low Expression of Activation and Inhibitory Molecules on NK Cells and CD4(+) T Cells Is Associated with Viral Control

scientific article published on 31 March 2015

Substantial intrapatient differences in the breadth and specificity of HIV-specific CD8+ T-cell interferon-gamma and proliferation responses.

scientific article published in October 2008

Targeting the chemokine receptor CCR5: good for HIV, what about other viruses?

scientific article published on January 2011

The replicative activity of human endogenous retrovirus K102 (HERV-K102) with HIV viremia

article

The role of G protein gene GNB3 C825T polymorphism in HIV-1 acquisition, progression and immune activation

scientific article published on 3 January 2012

The role of polymorphisms in host immune genes in determining the severity of respiratory illness caused by pandemic H1N1 influenza

scientific article

The role of regulatory T cells in chronic and acute viral infections

scientific article published on April 2008

Toll-Like Receptors Dysregulation after Influenza Virus Infection: Insights into Pathogenesis of Subsequent Bacterial Pneumonia

scholarly article by Yoav Keynan et al published 2011 in ISRN pulmonology

Using safe, affordable and accessible non-steroidal anti-inflammatory drugs to reduce the number of HIV target cells in the blood and at the female genital tract

article

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