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List of works by Gary Yellen

A PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging

scientific article published on 02 April 2014

A genetically encoded fluorescent reporter of ATP:ADP ratio

scientific article published on 4 January 2009

A high-throughput multiparameter screen for accelerated development and optimization of soluble genetically encoded fluorescent biosensors

scientific article published on 25 May 2022

A novel K+ channel with unique localizations in mammalian brain: molecular cloning and characterization

scientific article published on March 1, 1992

A perturbation-based method for calculating explicit likelihood of evolutionary co-variance in multiple sequence alignments.

scientific article

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

scientific article published on 14 December 2017

Alternative mechanism for pathogenesis of an inherited epilepsy by a nicotinic AChR mutation

scientific article published on 01 August 1996

BAD and KATP channels regulate neuron excitability and epileptiform activity.

scientific article

BAD knockout provides metabolic seizure resistance in a genetic model of epilepsy with sudden unexplained death in epilepsy

scientific article published on 23 November 2017

BAD-Dependent Regulation of Fuel Metabolism and KATP Channel Activity Confers Resistance to Epileptic Seizures ⬇️

scientific article published on May 24, 2012

Blocker protection in the pore of a voltage-gated K+ channel and its structural implications

scientific article published on 01 January 2000

Blocker state dependence and trapping in hyperpolarization-activated cation channels: evidence for an intracellular activation gate

scientific article

Charge movement in gating-locked HCN channels reveals weak coupling of voltage sensors and gate.

scientific article

Cytosolic NADH-NAD(+) Redox Visualized in Brain Slices by Two-Photon Fluorescence Lifetime Biosensor Imaging.

scientific article published on 9 February 2016

Dimers among friends: ion channel regulation by dimerization of tail domains

scientific article published on 01 September 2001

Expression of Torpedo nicotinic acetylcholine receptor subunits in yeast is enhanced by use of yeast signal sequences

scientific article

Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism

scientific article published on 11 May 2018

Gated access to the pore of a voltage-dependent K+ channel

scientific article published on 01 July 1997

Hepatic NADH reductive stress underlies common variation in metabolic traits

scientific article published on 27 May 2020

Imaging changes in the cytosolic ATP-to-ADP ratio.

scientific article published in January 2014

Imaging cytosolic NADH-NAD(+) redox state with a genetically encoded fluorescent biosensor

scientific article

Imaging intracellular pH in live cells with a genetically encoded red fluorescent protein sensor.

scientific article

Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges.

scientific article

Ion effects on gating of the Ca(2+)-activated K+ channel correlate with occupancy of the pore ⬇️

scientific article published on March 1, 1992

Ionic permeation and blockade in Ca2+-activated K+ channels of bovine chromaffin cells ⬇️

scientific article published on August 1, 1984

Keeping K+ completely comfortable

scientific article published on 01 December 2001

Ketogenic diet metabolites reduce firing in central neurons by opening K(ATP) channels

scientific article

Live cell imaging of cytosolic NADH/NAD+ ratio in hepatocytes and liver slices

scientific article

Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels

scientific article

Modulation of K+ current by frequency and external [K+]: a tale of two inactivation mechanisms.

scientific article

Movements near the gate of a hyperpolarization-activated cation channel

scientific article

Neuronal Stimulation Triggers Neuronal Glycolysis and Not Lactate Uptake

scientific article

Neurons rely on glucose rather than astrocytic lactate during stimulation

scientific article published on 21 December 2018

Optogenetic reporters: Fluorescent protein-based genetically encoded indicators of signaling and metabolism in the brain

scientific article published on January 2012

Premonitions of ion channel gating

scientific article published on June 1, 1998

Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step.

scientific article

Quantitative in vivo imaging of neuronal glucose concentrations with a genetically encoded fluorescence lifetime sensor.

scientific article published on 20 May 2019

Quantitative two-photon imaging of fluorescent biosensors

scientific article

Single Ca2+-activated nonselective cation channels in neuroblastoma ⬇️

scientific article published on March 25, 1982

Single Channel Seeks Permeant Ion for Brief but Intimate Relationship ⬇️

scientific article published on August 1, 1997

Single KATP Channel Opening in Response to Action Potential Firing in Mouse Dentate Granule Neurons ⬇️

scientific article published on June 8, 2011

Status of the intracellular gate in the activated-not-open state of shaker K+ channels

scientific article published on November 2005

Structural changes during HCN channel gating defined by high affinity metal bridges.

scientific article

Structure and selectivity

scientific article published in Nature

The Activation Gate of a Voltage-Gated K+ Channel Can Be Trapped in the Open State by an Intersubunit Metal Bridge ⬇️

scientific article published on September 1, 1998

The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle

scientific article published in 2021

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons

scientific article published on 13 May 2016

The voltage-gated potassium channels and their relatives

scientific article

Trapping of organic blockers by closing of voltage-dependent K+ channels: evidence for a trap door mechanism of activation gating.

scientific article published in May 1997

Two functionally distinct subsites for the binding of internal blockers to the pore of voltage-activated K+ channels

scientific article published on November 1996

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