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List of works by Thierry Soussi

A functional analysis of p53 during early development of Xenopus laevis.

scientific article

A monoclonal antibody against DNA binding helix of p53 protein

scientific article published on 01 March 2001

A new set of monoclonal antibodies directed to proline-rich and central regions of p53.

scientific article published in October 2004

APC gene: database of germline and somatic mutations in human tumors and cell lines

article

Absence of p53 germ-line mutations in bilateral breast cancer patients

scientific article published on 01 May 1992

Advances in carcinogenesis: A historical perspective from observational studies to tumor genome sequencing and TP53 mutation spectrum analysis ⬇️

scientific article published on July 23, 2011

Analysis of TP53 mutation status in human cancer cell lines: a reassessment

scientific article published on 6 May 2014

Analysis of p53 antibodies in patients with various cancers define B-cell epitopes of human p53: distribution on primary structure and exposure on protein surface

article

Analysis of p53 antibody response in patients with squamous cell carcinoma of the head and neck

scientific article published on 01 July 1996

Analysis of p53 serum antibodies in patients with head and neck squamous cell carcinoma

scientific article published on 01 September 1996

Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

scientific article

Anti-apoptotic activity of p53 maps to the COOH-terminal domain and is retained in a highly oncogenic natural mutant

scientific article published on 01 August 1999

Anti-p53 antibodies are rarely detected in serum of patients with rheumatoid arthritis and Sjögren's syndrome

scientific article published on 01 August 1999

Antibodies against p53 protein in serum of patients with benign or malignant pancreatic and biliary diseases.

scientific article published on March 1995

Author Correction: Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux

scientific article published on 03 April 2019

Breast-cancer stromal cells with TP53 mutations

scientific article published in April 2008

Can we predict solar ultraviolet radiation as the causal event in human tumours by analysing the mutation spectra of the p53 gene?

scientific article

Cancer and the heat shock response.

scientific article published on January 1994

Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73

scientific article published in Journal of Biological Chemistry

Critical residues of epitopes recognized by several anti-p53 monoclonal antibodies correspond to key residues of p53 involved in interactions with the mdm2 protein

scientific article published on 01 October 2000

DNA-binding properties of the major structural protein of simian virus 40

scientific article published on September 1986

Data mining the p53 pathway in the Fugu genome: evidence for strong conservation of the apoptotic pathway

scientific article

Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors

scientific article

Database and software for the analysis of mutations at the human p53 gene.

scientific article published on September 1994

Databases and software for the analysis of mutations in the human p53 gene, human hprt gene and both the lacI and lacZ gene in transgenic rodents ⬇️

scientific article published on January 1, 1998

Databases and software for the analysis of mutations in the human p53 gene, the human hprt gene and both the lacI and lacZ gene in transgenic rodents.

scientific article published on January 1997

Databases and software for the analysis of mutations in the human p53 gene, the human hprt gene and the lacZ gene in transgenic rodents.

scientific article published on January 1996

Detection and sequencing of p53 gene mutations in bronchial biopsy samples in patients with lung cancer

scientific article published on 01 October 1994

Detection of p73 antibodies in patients with various types of cancer: immunological characterization

scientific article published on January 2001

ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation

scientific article published on 2 February 2018

Effects of electrical brainstem stimulation on tinnitus.

scientific article

Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog

scientific article published on 07 March 2022

Expression of p53 in oral squamous cell carcinoma is associated with the presence of IgG and IgA p53 autoantibodies in sera and saliva of the patients

scientific article published on 01 September 2000

Fiche n 33 : BCR

scientific article published on 01 March 2000

File no.47: CMYC

scientific article published on 01 November 2001

Focus on the p53 gene and cancer: advances in TP53 mutation research

scientific article published on 01 March 2003

Foreign bodies in the respiratory tract. Diagnosis and treatment

scientific article published in June 1996

Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study.

scientific article published on 8 March 2006

Genetic alterations in localized prostate cancer: Identification of a common region of deletion on chromosome arm 18q

scientific article published on 01 October 1994

Genetic profiling of CLL: a 'TP53 addict' perspective.

scientific article

Genetics and cancer: fundamental and clinical aspects

scientific article published in November 2001

Germline mutations of the p53 tumor-suppressor gene in cancer-prone families: a review

scientific article published on 01 February 1993

Harmonized microarray/mutation scanning analysis of TP53 mutations in undissected colorectal tumors.

scientific article

High prevalence of cancer-associated TP53 variants in the gnomAD database: A word of caution concerning the use of variant filtering

scientific article published on 28 March 2019

Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene

scientific article published on 30 November 2020

Identification of cancer sex-disparity in the functional integrity of p53 and its X chromosome network

scientific article published on 26 November 2019

Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas

scientific article published on 01 July 2019

Is p53 a protein that predicts the response to chemotherapy in node negative breast cancer?

scientific article published on 01 January 1998

Lack of HIN-1 methylation defines specific breast tumor subtypes including medullary carcinoma of the breast and BRCA1-linked tumors

scientific article

Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate

scientific article published on 01 April 2019

Linear antigenic sites defined by the B-cell response to human p53 are localized predominantly in the amino and carboxy-termini of the protein

scientific article published on 01 July 1994

Locus-specific databases in cancer: what future in a post-genomic era? The TP53 LSDB paradigm

scientific article published on 05 March 2014

Locus-specific mutation databases: pitfalls and good practice based on the p53 experience

scientific article published on 01 January 2006

Lymphomas in patients with Sjogren's syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal sites, and are not associated with viruses

scientific article published on 01 July 1997

MUT-TP53 2.0: a novel versatile matrix for statistical analysis of TP53 mutations in human cancer

scientific article published in September 2010

MUT-TP53: a versatile matrix for TP53 mutation verification and publication

scientific article published on 01 November 2006

Medullary breast carcinoma: prognostic implications of p53 expression

scientific article published on 01 April 2003

Meta-analysis of the p53 Mutation Database for Mutant p53 Biological Activity Reveals a Methodologic Bias in Mutation Detection

article

Molecular genetic analysis of p53 intratumoral heterogeneity in human astrocytic brain tumors.

scientific article

Monitoring of p53 autoantibodies in lung cancer during therapy: relationship to response to treatment.

scientific article published on June 1998

Monoclonal antibodies raised against Xenopus p53 interact with human p73

scientific article published in February 2002

Mutant p53 protein localized in the cytoplasm inhibits autophagy

scientific article published on 6 October 2008

Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint.

scientific article published on June 1999

Mutations in TP53 are exclusively associated with del(17p) in multiple myeloma

scientific article

Mutations in p53 produce a common conformational effect that can be detected with a panel of monoclonal antibodies directed toward the central part of the p53 protein

scientific article published on 01 December 1994

Nucleotide sequence of a cDNA encoding the rat p53 nuclear oncoprotein.

scientific article published on December 1988

P53 gene alterations in human tumors: perspectives for cancer control.

scientific article published on January 1997

Perspectives of practical application for studies of gene p53

scientific article published in January 1994

Primary proliferative T cell response to wild-type p53 protein in patients with breast cancer

scientific article published on 01 June 1995

Production of human p53 specific monoclonal antibodies and their use in immunohistochemical studies of tumor cells

scientific article published on 01 February 1993

Prognostic significance of circulating P53 antibodies in patients undergoing surgery for locoregional breast cancer.

scientific article published in March 1995

Prognostic significance of serum p53 antibodies in patients with limited-stage small cell lung cancer.

scientific article published on January 2000

Quantitative fish determination of chromosome 3 arm imbalances in lung tumors by automated image cytometry

scientific article published on 26 October 2004

Rainbow trout p53: cDNA cloning and biochemical characterization

scientific article

Rapid and sensitive p53 alteration analysis in biopsies from lung cancer patients using a functional assay and a universal oligonucleotide array: a prospective study

scientific article published in May 2004

Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations

scientific article

Recommendations for analyzing and reporting TP53 gene variants in the high-throughput sequencing era.

scientific article published on 06 May 2014

Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

scientific article

Regulation of mutant p53 temperature-sensitive DNA binding.

scientific article

Regulation of the specific DNA binding activity of Xenopus laevis p53: evidence for conserved regulation through the carboxy-terminus of the protein

scientific article

Serum p53 antibodies as early markers of lung cancer

scientific article published on 01 July 1995

Serum p53 antibodies in correlation to other biological parameters of breast cancer

scientific article published on 01 January 2003

Serum p53 antibodies in patients with lung cancer: correlation with clinicopathologic features and smoking

scientific article published on 01 March 2003

Serum p53 antibodies in small cell lung cancer: the lack of prognostic relevance

scientific article published on 01 January 2001

Serum p53 antibody assay: evaluation in colorectal cancer

scientific article published on 01 February 2000

Seshat: A Web service for accurate annotation, validation, and analysis of TP53 variants generated by conventional and next-generation sequencing

scientific article published on 17 May 2018

Shaping genetic alterations in human cancer: the p53 mutation paradigm

scientific article published on October 2007

Significance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides

scientific article

Single-molecule DNA sequencing of acute myeloid leukemia and myelodysplastic syndromes with multiple TP53 alterations.

scientific article published on 27 October 2017

Splice mutations in the p53 gene: case report and review of the literature.

scientific article

Squamous cell carcinomas after allogeneic bone marrow transplantation for aplastic anemia: further evidence of a multistep process

scientific article published on 01 September 1998

Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux

scientific article published on 11 March 2019

Stabilization and expression of high levels of p53 during early development in Xenopus laevis.

scientific article published on September 1993

Stimulation of rat liver alpha- and beta-type DNA polymerases by an homologous DNA-unwinding protein

scientific article published on 01 July 1977

Structural aspects of the p53 protein in relation to gene evolution: a second look.

scientific article published on August 1996

Synonymous Somatic Variants in Human Cancer Are Not Infamous: A Plea for Full Disclosure in Databases and Publications.

scientific article published on 27 December 2016

TP53 Mutations in Human Cancer: Database Reassessment and Prospects for the Next Decade

scientific article published on January 1, 2011

TP53 and 53BP1 Reunited

scientific article published on 17 November 2016

TP53 mutation profile in chronic lymphocytic leukemia: evidence for a disease specific profile from a comprehensive analysis of 268 mutations

scientific article published on 23 September 2010

TP53 mutations are early events in chronic lymphocytic leukemia disease progression and precede evolution to complex karyotypes

scientific article published on 7 June 2016

TP53 mutations in human cancer: database reassessment and prospects for the next decade

scientific article published on June 2014

TP53 tumor suppressor gene: a model for investigating human mutagenesis

scientific article published on January 1, 1992

TP53: an oncogene in disguise.

scientific article published on 29 May 2015

Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice

scientific article

The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: influence of tumor site, type of mutation, and adjuvant treatment

scientific article

The TP53 gene network in a postgenomic era.

scientific article published on June 2014

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis.

scientific article published on 17 November 2012

The UMD TP53 database and website: update and revisions

scientific article published on 01 January 2006

The UMD-p53 database: new mutations and analysis tools

scientific article

The cDNA cloning and immunological characterization of hamster p53.

scientific article

The history of p53. A perfect example of the drawbacks of scientific paradigms

scientific article

The human BTG2/TIS21/PC3 gene: genomic structure, transcriptional regulation and evaluation as a candidate tumor suppressor gene

scientific article (publication date: 9 January 2002)

The humoral response to the tumor-suppressor gene-product p53 in human cancer: implications for diagnosis and therapy

scientific article published on 01 August 1996

The p53 gene and protein in bronchial carcinogenesis:from biological to clinical aspects

scientific article published in January 1994

The p53 pathway and human cancer

scientific article published on 01 November 2005

The p53 tumor suppressor gene: from molecular biology to clinical investigation.

scientific article published in June 2000

The role of p53 in normal cells and in cancer development

scientific article published on 01 December 1997

ThinPrep-processed fine-needle samples of breast are effective material for RNA- and DNA-based molecular diagnosis: application to p53 mutation analysis.

scientific article published on August 2003

UMD (Universal Mutation Database): 2005 update

scientific article

Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan

scientific article published on 01 July 2019

Versatile analysis of multiple macromolecular interactions by SPR imaging: application to p53 and DNA interaction

scientific article published in July 2004

Very low incidence of p53 antibodies in adult non-Hodgkin's lymphoma and multiple myeloma

scientific article published on 01 January 1998

When mutant p53 plays hide and seek: a new challenge for diagnosis and therapy?

scientific article published on 25 December 2008

Xenopus laevis p53 protein: sequence-specific DNA binding, transcriptional regulation and oligomerization are evolutionarily conserved.

scientific article published on February 1995

[44 .PMS2 (post meiotic segregation increased, S. cerevisiae 2]

scientific article published on 01 April 2001

[BLM (RCQL2) or Bloom Syndrome]

scientific article published on 01 February 2001

[Bcl2-associated X protein]

scientific article published on 01 March 2001

[Card no. 32: ATM (Ataxia Telangiectasia Mutated)]

scientific article published on 01 February 2000

[Case No. 36: E-cadherin (uvomorulin or CDH1]

scientific article published on 01 September 2000

[Case No. 37: hdm2 (mdm2 in mice)]

scientific article published on 01 September 2000

[Chart 48: FANCG/XRCC9 (type G Fanconi's anemia)]

scientific article published on 01 December 2001

[Chart no 45 - WRN (RCQL3)]

scientific article published on 01 June 2001

[Chart no. 30: FANCA (Fanconi's anemia type A). Repair gene?]

scientific article published on 01 November 1999

[File no. 40. DNA polymerase n (Pol H) in hRad30A. Repair gene]

scientific article published on 01 November 2000

[File no. 41. VHL (von Hippel-Lindau). Tumor suppressor gene]

scientific article published on 01 November 2000

[Genes & cancer. Card no. 28: PTEN (MMAC, TEP-1) (phosphatase and tensin homolog deleted on chromosome 10)]

scientific article published on 01 September 1999

[Genes and cancer. NBS1 (Nijmegen breakage syndrome). Repair gene]

scientific article published on 01 October 1999

[Ha-ras, N-ras et Ki-ras]

scientific article published on 01 February 2001

[INK4a-ARF (MTS1) or inhibitor of CDK-alternating reading frame (multiple tumor suppressor gene)]

scientific article published on 01 July 1999

[Immunochemistry and genotype analysis of tumors. Second part: What future for the molecular diagnosis of tumors?]

scientific article published on 01 April 2002

[Li-Fraumeni syndrome and germ-line mutations of the p53 gene]

scientific article published on 01 January 1994

[P53 antibodies: a new method for the analysis of alterations of the p53 gene: application to breast cancer]

scientific article published on 01 April 1996

[P53 tumor suppressor gene]

scientific article published on 01 February 1993

[PML (promyelocytic leukemia). Oncogene]

scientific article published on 01 February 1999

[PTPC (Patched). Tumor suppressor gene]

scientific article published on 01 February 1999

[Record no. 22: Beta-catenin]

scientific article

[Record no. 23: hMLH1]

scientific article published on 01 March 1999

[Record no. 34: hSNF5/INI1 (SMARCB1)]

scientific article published on 01 April 2000

[Record no. 38: TGFBR2 (type II TGFbeta receptor)]

scientific article published on 01 October 2000

[Record no. 39: p53 (TP53)]

scientific article published on 01 October 2000

[Role of the p53 gene in human malignant tumors. A major discovery in oncology]

scientific article published on 01 December 1993

[Tumor suppressor p53 gene: a potential target for cancer therapy?]

scientific article published on 01 July 1997

[p53 and Rb, clinical and therapeutic perspectives]

scientific article published on 01 January 1993

[p53 mutations and resistance to chemotherapy: a stab in the back for p73?].

scientific article

p53 Website and analysis of p53 gene mutations in human cancer: Forging a link between epidemiology and carcinogenesis

article

p53 alterations in human cancer: more questions than answers.

scientific article published on April 2007

p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: a prospective series.

scientific article published in April 2000

p53 antibodies in the saliva of patients with squamous cell carcinoma of the oral cavity

scientific article published on 01 October 1998

p53 antibodies in the sera of lung cancer patients: comparison with p53 mutation in the tumour tissue

scientific article published on 01 June 1995

p53 gene alterations in human hematological malignancies: a review

scientific article published on 01 January 1991

p53 gene mutation: software and database

article

p53 gene mutation: software and database.

scientific article

p53 immunolabeling in archival paraffin-embedded tissues: optimal protocol based on microwave heating for eight antibodies on lung carcinomas.

scientific article published on October 1994

p53 mutation as a genetic trait of typical medullary breast carcinoma

scientific article published on 01 April 1999

p53 mutations and resistance to chemotherapy: A stab in the back for p73 ⬇️

scientific article published on April 1, 2003

p53 mutations in BRCA1-associated familial breast cancer

scientific article published in The Lancet

p53-dependent pathway of radio-induced apoptosis is altered in Fanconi anemia

scientific article published on 01 January 1995

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