List of works by Héctor Escobar Morreale

2D Diffusion-Ordered 1H-NMR Spectroscopy Lipidomic Profiling After Oral Single Macronutrient Loads: Influence of Obesity, Sex, and Female Androgen Excess

scientific article published on 18 March 2020

A nontargeted proteomic approach to the study of visceral and subcutaneous adipose tissue in human obesity.

scientific article

A nontargeted proteomic study of the influence of androgen excess on human visceral and subcutaneous adipose tissue proteomes.

scientific article

A nontargeted study of muscle proteome in severely obese women with androgen excess compared with severely obese men and nonhyperandrogenic women.

scientific article published on 15 December 2015

A prospective study of the prevalence of nonclassical congenital adrenal hyperplasia among women presenting with hyperandrogenic symptoms and signs.

scientific article

A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain.

scientific article published in July 2000

A safety evaluation of current medications for adult women with the polycystic ovarian syndrome not pursuing pregnancy

scientific article published on 17 October 2020

A study of the hexose-6-phosphate dehydrogenase gene R453Q and 11beta-hydroxysteroid dehydrogenase type 1 gene 83557insA polymorphisms in the polycystic ovary syndrome.

scientific article published on 12 April 2005

Abdominal adiposity and the polycystic ovary syndrome.

scientific article published on 10 August 2007

Abnormalities in the serum insulin-like growth factor-1 axis in women with hyperandrogenism

scientific article published in December 1998

Adiponectin and resistin in PCOS: a clinical, biochemical and molecular genetic study

scientific article published on 04 May 2006

Adrenal Hyperandrogenism and Polycystic Ovary Syndrome

scientific article published on 20 July 2016

Androgen Excess in Women: Proteomic and Metabolomic Approaches

scientific article published on 09 September 2019

Androgen excess is associated with the increased carotid intima-media thickness observed in young women with polycystic ovary syndrome

scientific article published on 11 October 2007

Androgens and polycystic ovary syndrome

scientific article published on 01 January 2012

Antiandrogenic contraceptives increase serum adiponectin in obese polycystic ovary syndrome patients

scientific article

Apparent mineralocorticoid excess as a side effect of ketoconazole therapy in a patient with Cushing's disease

scientific article published on 15 November 2019

Association between the D19S884 marker at the insulin receptor gene locus and polycystic ovary syndrome

scientific article published on 01 January 2003

Association of Cardiovascular Autonomic Dysfunction With Peripheral Arterial Stiffness in Patients With Type 1 Diabetes

scientific article published on 01 July 2019

Association of TLR2 S450S and ICAM1 K469E polymorphisms with polycystic ovary syndrome (PCOS) and obesity.

scientific article published on 9 October 2015

Association of the polycystic ovary syndrome with genomic variants related to insulin resistance, type 2 diabetes mellitus, and obesity

scientific article

Beneficial changes on plasma apolipoproteins A and B, high density lipoproteins and oxidized low density lipoproteins in obese women after bariatric surgery: comparison between gastric bypass and sleeve gastrectomy.

scientific article

Body iron stores and glucose intolerance in premenopausal women: role of hyperandrogenism, insulin resistance, and genomic variants related to inflammation, oxidative stress, and iron metabolism

scientific article published on 28 April 2009

Body iron stores are increased in overweight and obese women with polycystic ovary syndrome.

scientific article published in August 2005

Cardiac involvement in acromegaly: specific myocardiopathy or consequence of systemic hypertension?

scientific article published on 01 April 1997

Certified testosterone immunoassays for hyperandrogenaemia

scientific article published on 08 October 2018

Chronic thyrotropin-suppressive therapy with levothyroxine and short-term overt hypothyroidism after thyroxine withdrawal are associated with undesirable cardiovascular effects in patients with differentiated thyroid carcinoma.

scientific article

Circulating adiponectin increases in obese women after sleeve gastrectomy or gastric bypass driving beneficial metabolic changes but with no relationship with carotid intima-media thickness

scientific article published on 12 October 2017

Circulating inflammatory markers in polycystic ovary syndrome: a systematic review and metaanalysis.

scientific article

Circulating leptin concentrations in women with hirsutism

scientific article published in November 1997

Circulating soluble klotho is not associated with an elevated ankle-brachial index as a surrogate marker of early arterial calcification in patients with type 1 diabetes mellitus and no evidence of renal dysfunction.

scientific article published on 18 January 2018

Combined oral contraceptives and/or antiandrogens versus insulin sensitizers for polycystic ovary syndrome: a systematic review and meta-analysis

scientific article published on 27 December 2017

Combined oral contraceptives plus spironolactone compared with metformin in women with polycystic ovary syndrome: a one-year randomized clinical trial

scientific article published on November 2017

Comment: the methionine 196 arginine polymorphism in exon 6 of the TNF receptor 2 gene (TNFRSF1B) is associated with the polycystic ovary syndrome and hyperandrogenism

scientific article published in August 2002

Common single nucleotide polymorphisms in intron 3 of the calpain-10 gene influence hirsutism

scientific article published in March 2002

Common variants in the sex hormone-binding globulin gene (SHBG) and polycystic ovary syndrome (PCOS) in Mediterranean women.

scientific article published on 20 September 2012

Comparison of ethinyl-estradiol plus cyproterone acetate versus metformin effects on classic metabolic cardiovascular risk factors in women with the polycystic ovary syndrome

scientific article published on 10 April 2007

Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

scientific article (publication date: November 2006)

Definition and significance of polycystic ovarian morphology: a task force report from the Androgen Excess and Polycystic Ovary Syndrome Society

scientific article

Diagnosis and management of hirsutism.

scientific article published on September 2010

Diagnosis of disorders of glucose tolerance in women with polycystic ovary syndrome (PCOS) at a tertiary care center: fasting plasma glucose or oral glucose tolerance test?

scientific article published on 30 January 2019

Diet composition and physical activity in overweight and obese premenopausal women with or without polycystic ovary syndrome

scientific article published on 24 May 2011

Differences in analytical and biological results between older and newer lots of a widely used irisin immunoassay question the validity of previous studies.

scientific article published on 17 December 2015

Effects of ?-Arginine Infusion on Renal Hemodynamics and Sodium Excretion During Hypo-, Normo-, and Hyperinsulinemia, as Studied in Dogs

scientific article published on 01 July 1996

Effects of bariatric surgery on male obesity-associated secondary hypogonadism: comparison of laparoscopic gastric bypass with restrictive procedures.

scientific article published in October 2014

Effects of glucose ingestion on circulating inflammatory mediators: Influence of sex and weight excess

scientific article published on 29 January 2016

Effects of metformin versus ethinyl-estradiol plus cyproterone acetate on ambulatory blood pressure monitoring and carotid intima media thickness in women with the polycystic ovary syndrome

scientific article published on 18 June 2008

Effects of normalization of GH hypersecretion on lipoprotein(a) and other lipoprotein serum levels in acromegaly

scientific article published on 01 September 2000

Effects of polycystic ovary syndrome (PCOS), sex hormones, and obesity on circulating miRNA-21, miRNA-27b, miRNA-103, and miRNA-155 expression

scientific article published on 13 September 2013

Effects of thyroid hormones on serum levels of adipokines as studied in patients with differentiated thyroid carcinoma during thyroxine withdrawal.

scientific article published in April 2006

Efficacy and Safety of SGLT2 Inhibitors in Type 1 Diabetes After the Introduction of an Off-Label Use Protocol for Clinical Practice

scientific article published on 23 October 2019

Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society.

scientific article

European survey of diagnosis and management of the polycystic ovary syndrome: results of the ESE PCOS Special Interest Group's Questionnaire

scientific article published on 21 July 2014

Evidence for masculinization of adipokine gene expression in visceral and subcutaneous adipose tissue of obese women with polycystic ovary syndrome (PCOS).

scientific article

Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee

scientific article published on 01 July 2019

Genomic variants in polycystic ovary syndrome.

scientific article

Global adiposity and thickness of intraperitoneal and mesenteric adipose tissue depots are increased in women with polycystic ovary syndrome (PCOS).

scientific article

Glycoprotein A and B Height-to-Width Ratios as Obesity-Independent Novel Biomarkers of Low-Grade Chronic Inflammation in Women with Polycystic Ovary Syndrome (PCOS)

scientific article published on 27 September 2019

Gut Microbiota and the Polycystic Ovary Syndrome: Influence of Sex, Sex Hormones, and Obesity

scientific article published on 01 July 2018

High prevalence of the polycystic ovary syndrome and hirsutism in women with type 1 diabetes mellitus.

scientific article published in November 2000

Hyperandrogenism, insulin resistance and hyperinsulinemia as cardiovascular risk factors in diabetes mellitus.

scientific article published on February 2006

Identification of reduced circulating haptoglobin concentration as a biomarker of the severity of pulmonary embolism: a nontargeted proteomic study

scientific article (publication date: 2014)

Impact of the storage temperature on human plasma proteomic analysis: implications for the use of human plasma collections in research.

scientific article

Improved resolution of the human adipose tissue proteome at alkaline and wide range pH by the addition of hydroxyethyl disulfide.

scientific article published in February 2004

Improvement in cardiovascular risk in women after bariatric surgery as measured by carotid intima-media thickness: comparison of sleeve gastrectomy versus gastric bypass.

scientific article published on 3 February 2017

Increased body iron stores of obese women with polycystic ovary syndrome are a consequence of insulin resistance and hyperinsulinism and are not a result of reduced menstrual losses

scientific article published on 29 May 2007

Influence of adrenal hyperandrogenism on the clinical and metabolic phenotype of women with polycystic ovary syndrome.

scientific article published on 10 January 2015

Insulin gene variable number of tandem repeats regulatory polymorphism is not associated with hyperandrogenism in Spanish women

scientific article

Iron metabolism and the polycystic ovary syndrome.

scientific article published on 10 May 2012

Isolated adrenocorticotropic hormone deficiency due to probable lymphocytic hypophysitis in a man.

scientific article published in February 1994

Lack of Improvement of Sperm Characteristics in Obese Males After Obesity Surgery Despite the Beneficial Changes Observed in Reproductive Hormones

scientific article published on 01 July 2019

Lack of an ovarian function influence on the increased adrenal androgen secretion present in women with functional ovarian hyperandrogenism

scientific article published on 01 April 1997

Macroprolactinemia in women presenting with hyperandrogenic symptoms: Implications for the management of polycystic ovary syndrome

scientific article published on 01 December 2004

Management of postmenopausal virilization

scientific article published on 5 June 2012

Mechanisms of adaptation to iodine deficiency in rats: thyroid status is tissue specific. Its relevance for man.

scientific article published on 2 February 2006

Mediators of low-grade chronic inflammation in polycystic ovary syndrome (PCOS).

scientific article published on January 2013

Metabolic Cytokines at Fasting and During Macronutrient Challenges: Influence of Obesity, Female Androgen Excess and Sex

scientific article published on 24 October 2019

Metabolic Heterogeneity in Polycystic Ovary Syndrome Is Determined by Obesity: Plasma Metabolomic Approach Using GC-MS

scientific article published on 16 March 2012

Metabolomics in polycystic ovary syndrome.

scientific article published on 22 December 2013

Mild adrenal and ovarian steroidogenic abnormalities in hirsute women without hyperandrogenemia: does idiopathic hirsutism exist?

scientific article published in August 1997

Mutations in the hereditary hemochromatosis gene are not associated with the increased body iron stores observed in overweight and obese women with polycystic ovary syndrome

scientific article published on 01 November 2006

Non-classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency revisited: an update with a special focus on adolescent and adult women

scientific article published on 05 June 2017

Non-targeted profiling of circulating microRNAs in women with polycystic ovary syndrome (PCOS): effects of obesity and sex hormones

scientific article published in February 2018

Obesity impairs general health-related quality of life (HR-QoL) in premenopausal women to a greater extent than polycystic ovary syndrome (PCOS)

scientific article published on 01 November 2010

Obesity is the major determinant of the abnormalities in blood pressure found in young women with the polycystic ovary syndrome

scientific article published on 27 March 2007

Office blood pressure, ambulatory blood pressure monitoring, and echocardiographic abnormalities in women with polycystic ovary syndrome: role of obesity and androgen excess.

scientific article published on 9 December 2013

Only the combined treatment with thyroxine and triiodothyronine ensures euthyroidism in all tissues of the thyroidectomized rat

scientific article published on 01 June 1996

Pharmacotherapeutic management of comorbid polycystic ovary syndrome and diabetes

scientific article published on 05 October 2018

Plasma thiobarbituric acid reactive substances (TBARS) in young adults: Obesity increases fasting levels only in men whereas glucose ingestion, and not protein or lipid intake, increases postprandial concentrations regardless of sex and obesity.

scientific article

Polycystic ovary syndrome as a paradigm for prehypertension, prediabetes, and preobesity

scientific article

Polycystic ovary syndrome in adult women

scientific article published on 04 January 2019

Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment.

scientific article published on 23 March 2018

Polymorphisms in the insulin receptor substrate-1 (IRS-1) gene and the insulin receptor substrate-2 (IRS-2) gene influence glucose homeostasis and body mass index in women with polycystic ovary syndrome and non-hyperandrogenic controls.

scientific article published on 21 July 2005

Polymorphisms in the interleukin-6 receptor gene are associated with body mass index and with characteristics of the metabolic syndrome

scientific article published on 01 July 2006

Postprandial inflammatory responses after oral glucose, lipid and protein challenges: Influence of obesity, sex and polycystic ovary syndrome

scientific article published on 01 April 2019

Prevalence and characteristics of the polycystic ovary syndrome in overweight and obese women

scientific article published on 01 October 2006

Prevalence of 'obesity-associated gonadal dysfunction' in severely obese men and women and its resolution after bariatric surgery: a systematic review and meta-analysis

scientific article published on 9 May 2017

Prevalence of PCOS and related hyperandrogenic traits in premenopausal women with type 1 diabetes: a systematic review and meta-analysis

scientific article published in 2022

Prevalence of functional disorders of androgen excess in unselected premenopausal women: a study in blood donors.

scientific article published on 17 February 2012

Prevalence of hyperprolactinaemia in female premenopausal blood donors.

scientific article published on 8 April 2013

Prevalence of male secondary hypogonadism in moderate to severe obesity and its relationship with insulin resistance and excess body weight.

scientific article published on 11 December 2015

Prospective randomized study comparing the long-acting gonadotropin-releasing hormone agonist triptorelin, flutamide, and cyproterone acetate, used in combination with an oral contraceptive, in the treatment of hirsutism

scientific article published on 01 January 1999

Proteomic analysis of adipose tissue: informing diabetes research.

scientific article published on 31 March 2014

Proteomic analysis of human omental adipose tissue in the polycystic ovary syndrome using two-dimensional difference gel electrophoresis and mass spectrometry

scientific article

Proteomic analysis of plasma in the polycystic ovary syndrome identifies novel markers involved in iron metabolism, acute-phase response, and inflammation.

scientific article published on 19 May 2010

Proteomic analysis of visceral adipose tissue in pre-obese patients with type 2 diabetes.

scientific article published on 18 June 2013

Proteomic and metabolomic approaches to the study of polycystic ovary syndrome.

scientific article published on 17 February 2013

Proteomics and genomics: A hypothesis-free approach to the study of the role of visceral adiposity in the pathogenesis of the polycystic ovary syndrome

scientific article published on 01 March 2008

Proteomics and polycystic ovary syndrome

scientific article published on 03 October 2013

Quality of life and psychometric functionality in patients with differentiated thyroid carcinoma.

scientific article

Referral bias in female functional hyperandrogenism and polycystic ovary syndrome.

scientific article published on 4 August 2015

Regulation of iodothyronine deiodinase activity as studied in thyroidectomized rats infused with thyroxine or triiodothyronine

scientific article published in June 1997

Reproductive endocrinology: Menstrual dysfunction--a proxy for insulin resistance in PCOS?

scientific article published on 26 November 2013

Reproductive outcome of women with 21-hydroxylase-deficient nonclassic adrenal hyperplasia.

scientific article published on 5 July 2006

Retinol and alpha-tocopherol in morbid obesity and nonalcoholic fatty liver disease.

scientific article

Role of androgen-mediated enhancement of erythropoiesis in the increased body iron stores of patients with polycystic ovary syndrome

scientific article published on 01 April 2011

Role of decreased circulating hepcidin concentrations in the iron excess of women with the polycystic ovary syndrome

scientific article published on 05 January 2011

Role of haptoglobin in polycystic ovary syndrome (PCOS), obesity and disorders of glucose tolerance in premenopausal women.

scientific article

Role of sampling times and serum cortisol cut-off concentrations on the routine assessment of adrenal function using the standard cosyntropin test in an academic hospital from Spain: a retrospective chart review.

scientific article

Role of the pentanucleotide (tttta)(n) polymorphism in the promoter of the CYP11a gene in the pathogenesis of hirsutism.

scientific article

Screening for mutations in the steroidogenic acute regulatory protein and steroidogenic factor-1 genes, and in CYP11A and dosage-sensitive sex reversal-adrenal hypoplasia gene on the X chromosome, gene-1 (DAX-1), in hyperandrogenic hirsute women

scientific article published in April 2001

Serum Bioavailable Vitamin D Concentrations and Bone Mineral Density in Women After Obesity Surgery

scientific article published on 26 April 2016

Serum Retinol, Folic Acid, and Copper Are Associated With Sperm Abnormalities in Men With Obesity

scientific article

Serum interleukin-18 concentrations are increased in the polycystic ovary syndrome: relationship to insulin resistance and to obesity.

scientific article published in February 2004

Serum osteoprotegerin concentrations are decreased in women with the polycystic ovary syndrome.

scientific article published on 25 June 2008

Serum prostate-specific antigen concentrations are not useful for monitoring the treatment of hirsutism with oral contraceptive pills

scientific article published on 01 July 2000

Serum uric acid concentration as non-classic cardiovascular risk factor in women with polycystic ovary syndrome: effect of treatment with ethinyl-estradiol plus cyproterone acetate versus metformin.

scientific article published on 27 March 2008

Serum visceral adipose tissue-derived serine protease inhibitor concentrations in human obesity and polycystic ovary syndrome

scientific article published on 01 January 2009

Sex differences in the characteristics and short-term prognosis of patients presenting with acute symptomatic pulmonary embolism

scientific article published on 6 November 2017

Sexual Dimorphism and Sex Steroids Influence Cardiovascular Autonomic Neuropathy in Patients With Type 1 Diabetes

scientific article published on 17 September 2019

Surrogate markers of visceral adiposity in young adults: waist circumference and body mass index are more accurate than waist hip ratio, model of adipose distribution and visceral adiposity index

scientific article

Systemic endocrinopathies (thyroid conditions and diabetes): impact on postnatal life of the offspring

scientific article published on 01 June 2019

TLR2 and TLR4 Surface and Gene Expression in White Blood Cells after Fasting and Oral Glucose, Lipid and Protein Challenges: Influence of Obesity and Sex Hormones

scientific article published on 09 January 2020

Targets to treat androgen excess in polycystic ovary syndrome.

scientific article published on 7 September 2015

The -597 G-->A and -174 G-->C polymorphisms in the promoter of the IL-6 gene are associated with hyperandrogenism

scientific article published in March 2002

The ACAA-insertion/deletion polymorphism at the 3′ UTR of the IGF-II receptor gene is associated with type 2 diabetes and surrogate markers of insulin resistance

article

The PON1-108C/T polymorphism, and not the polycystic ovary syndrome, is an important determinant of reduced serum paraoxonase activity in premenopausal women

scientific article published on 31 July 2006

The R453Q and D151A polymorphisms of hexose-6-phosphate dehydrogenase gene (H6PD) influence the polycystic ovary syndrome (PCOS) and obesity.

scientific article published on 28 January 2012

The Role of Androgen Excess in Metabolic Dysfunction in Women : Androgen Excess and Female Metabolic Dysfunction

scientific article published in January 2017

The decrease in serum IL-18 levels after bariatric surgery in morbidly obese women is a time-dependent event

scientific article published on 01 September 2007

The determinants of insulin sensitivity, β-cell function, and glucose tolerance are different in patients with polycystic ovary syndrome than in women who do not have hyperandrogenism

scientific article published on 25 January 2010

The effects of thyroid hormones on circulating markers of cell-mediated immune response, as studied in patients with differentiated thyroid carcinoma before and during thyroxine withdrawal.

scientific article published in August 2005

The increase in serum visfatin after bariatric surgery in morbidly obese women is modulated by weight loss, waist circumference, and presence or absence of diabetes before surgery

scientific article published on 19 March 2008

The increased circulating prostate-specific antigen concentrations in women with hirsutism do not respond to acute changes in adrenal or ovarian function

scientific article published in July 1998

The molecular-genetic basis of functional hyperandrogenism and the polycystic ovary syndrome.

scientific article

The peripheral atherosclerotic profile in patients with type 1 diabetes mellitus warrants a thorough vascular assessment of asymptomatic patients

scientific article published on 20 November 2018

The polycystic ovary syndrome associated with morbid obesity may resolve after weight loss induced by bariatric surgery

scientific article published on 27 September 2005

The polycystic ovary syndrome: a position statement from the European Society of Endocrinology

scientific article

The presence of the 21-hydroxylase deficiency carrier status in hirsute women: phenotype-genotype correlations

scientific article

The role of genetic variation in peroxisome proliferator-activated receptors in the polycystic ovary syndrome (PCOS): an original case-control study followed by systematic review and meta-analysis of existing evidence.

scientific article published on 04 August 2009

The role of serum osteoprotegerin and receptor-activator of nuclear factor-κB ligand in metabolic bone disease of women after obesity surgery.

scientific article published on 5 October 2015

The role of the CAG repeat polymorphism in the androgen receptor gene and of skewed X-chromosome inactivation, in the pathogenesis of hirsutism

scientific article published on 01 April 2000

The striking similarities in the metabolic associations of female androgen excess and male androgen deficiency

scientific article

Thyroid hormone deficiency and postmenopausal status independently increase serum osteoprotegerin concentrations in women

scientific article published on 01 May 2007

Tissue-specific patterns of changes in 3,5,3'-triiodo-L-thyronine concentrations in thyroidectomized rats infused with increasing doses of the hormone. Which are the regulatory mechanisms?

scientific article published on 01 May 1999

Treatment of Hypothyroidism with Combinations of Levothyroxine plus Liothyronine

scientific article

Treatment of hirsutism with ethinyl estradiol-desogestrel contraceptive pills has beneficial effects on the lipid profile and improves insulin sensitivity.

scientific article published in October 2000

Treatment of hypothyroidism with levothyroxine or a combination of levothyroxine plus L-triiodothyronine.

scientific article

Treatment of polycystic ovary syndrome (PCOS) with metformin ameliorates insulin resistance in parallel with the decrease of serum interleukin-6 concentrations.

scientific article published on 20 August 2010

Type 1 Diabetes and Polycystic Ovary Syndrome: Systematic Review and Meta-analysis

scientific article published on April 2016

Vitamin D deficiency is associated with the metabolic syndrome in morbid obesity

scientific article published on 10 July 2007

Weight gain and cardiovascular risk factors during smoking cessation with bupropion or nicotine.

scientific article published in March 2004