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List of works by Jessica Escoffier

A recurrent deletion of DPY19L2 causes infertility in man by blocking sperm head elongation and acrosome formation

scientific article

Bi-allelic Mutations in ARMC2 Lead to Severe Astheno-Teratozoospermia Due to Sperm Flagellum Malformations in Humans and Mice

scientific article published on 24 January 2019

Biphasic role of calcium in mouse sperm capacitation signaling pathways

scientific article published on August 2015

Compartmentalization of distinct cAMP signaling pathways in mammalian sperm

scientific article published on 15 October 2013

Creation of knock out and knock in mice by CRISPR/Cas9 to validate candidate genes for human male infertility, interest, difficulties and feasibility.

scientific article published on 6 March 2018

Deciphering Cell Lineage Specification during Male Sex Determination with Single-Cell RNA Sequencing

scientific article published in February 2018

Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development

scientific article

Dynamics of Sun5 localization during spermatogenesis in wild type and Dpy19l2 knock-out mice indicates that Sun5 is not involved in acrosome attachment to the nuclear envelope

scientific article

Electrophysiological evidence for the presence of cystic fibrosis transmembrane conductance regulator (CFTR) in mouse sperm

scientific article

Expression, localization and functions in acrosome reaction and sperm motility of CaV3.1 and CaV3.2 channels in sperm cells: An evaluation from CaV3.1 and CaV3.2 deficient mice

Flow cytometry analysis reveals that only a subpopulation of mouse sperm undergoes hyperpolarization during capacitation

scientific article

Group X phospholipase A2 is released during sperm acrosome reaction and controls fertility outcome in mice

scientific article

Group X secreted phospholipase A2 specifically decreases sperm motility in mice

scientific article published on 01 October 2011

Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP

scientific journal article

Ion permeabilities in mouse sperm reveal an external trigger for SLO3-dependent hyperpolarization.

scientific article

Les phospholipases, enzymes clés de la physiologie spermatique

scientific article published on 30 May 2012

MPC1-like Is a Placental Mammal-specific Mitochondrial Pyruvate Carrier Subunit Expressed in Postmeiotic Male Germ Cells.

scientific article published on 17 June 2016

Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human.

scientific article published on 15 February 2018

PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice.

scientific article

Pantoprazole, a proton pump inhibitor, impairs human sperm motility and capacitation in vitro

scientific article published on 01 July 2020

Progesterone-induced Acrosome Exocytosis Requires Sequential Involvement of Calcium-independent Phospholipase A2β (iPLA2β) and Group X Secreted Phospholipase A2 (sPLA2)

scientific article published on 11 December 2015

SPINK2 deficiency causes infertility by inducing sperm defects in heterozygotes and azoospermia in homozygotes

scientific article published on 29 May 2017

Slo3 K+ channel blocker clofilium extends bull and mouse sperm-fertilizing competence

scientific article published on 01 December 2018

Snake venoms as a source of compounds modulating sperm physiology: Secreted phospholipases A2 from Oxyuranus scutellatus scutellatus impact sperm motility, acrosome reaction and in vitro fertilization in mice

scientific article published on 11 March 2010

Spermaurin, an La1-like peptide from the venom of the scorpion Scorpio maurus palmatus, improves sperm motility and fertilization in different mammalian species.

scientific article

Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation

scientific article

Teratozoospermia: spotlight on the main genetic actors in the human

scientific article published on 17 April 2015

Testicular Dysgenesis Syndrome and Long-Lasting Epigenetic Silencing of Mouse Sperm Genes Involved in the Reproductive System after Prenatal Exposure to DEHP.

scientific article

The effect of group X secreted phospholipase A2 on fertilization outcome is specific and not mimicked by other secreted phospholipases A2 or progesterone

scientific article published on 25 November 2013

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