List of works - Tim J. McMahon

A novel inhaled organic nitrate that affects pulmonary vascular tone in a piglet model of hypoxia-induced pulmonary hypertension

scientific article

Antagonists of the system L neutral amino acid transporter (LAT) promote endothelial adhesivity of human red blood cells.

scientific article published on 6 April 2017

Automated measurement of blood flow velocity and direction and hemoglobin oxygen saturation in the rat lung using intravital microscopy

scientific article published on 16 November 2012

Biomarkers in Pulmonary Vascular Disease: Gauging Response to Therapy.

scientific article

Blockade of thromboxane/endoperoxide receptor-mediated responses in the pulmonary vascular bed of the cat by sulotroban

scientific article published on 01 March 1992

Blood Flow Regulation by S-Nitrosohemoglobin in the Physiological Oxygen Gradient

scientific article published in Science

Bronchodilator S-nitrosothiol deficiency in asthmatic respiratory failure

scientific article published in May 1998

Comparison of responses to pituitary adenylate cyclase activating peptides 38 and 27 in the pulmonary vascular bed of the cat

scientific article published on 01 October 1993

Concerted nitric oxide/oxygen delivery by hemoglobin

scientific article published on 01 January 1999

Drebrin regulates angiotensin II-induced aortic remodelling

scientific article published on 01 November 2018

Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock

scientific article (publication date: 20 February 2004)

Evolution of adverse changes in stored RBCs

scientific article

Excitation-contraction coupling in airway smooth muscle

scientific article

Extrapulmonary effects of inhaled nitric oxide: role of reversible S-nitrosylation of erythrocytic hemoglobin

scientific article

Functional coupling of oxygen binding and vasoactivity in S-nitrosohemoglobin

scientific article published on 01 June 2000

HGT in the human and skin commensal Malassezia: A bacterially derived flavohemoglobin is required for NO resistance and host interaction

scientific article published on 23 June 2020

Hemoglobin conformation couples erythrocyte S-nitrosothiol content to O2 gradients

scientific article

Impact of transfusion of autologous 7‐ versus 42‐day‐old AS‐3 red blood cells on tissue oxygenation and the microcirculation in healthy volunteers ⬇️

scientific article published on March 27, 2012

Impaired adenosine-5'-triphosphate release from red blood cells promotes their adhesion to endothelial cells: a mechanism of hypoxemia after transfusion.

scientific article

Influence of SQ 29,548 on vasoconstrictor responses in the hindquarters vascular bed of the cat.

scientific article

Influence of lemakalim on the pulmonary vascular bed of the cat

scientific article published on 01 September 1991

Inhaled nitric oxide therapy increases blood nitrite, nitrate, and s-nitrosohemoglobin concentrations in infants with pulmonary hypertension

scientific article published on 9 September 2011

Liberation of ATP secondary to hemolysis is not mutually exclusive of regulated export

scientific article published in March 2015

Nitric oxide in the human respiratory cycle.

scientific article published on 03 June 2002

Nitric oxide loading reduces sickle red cell adhesion and vaso-occlusion in vivo

scientific article published on 01 September 2019

Oxygen regulation of tumor perfusion by S-nitrosohemoglobin reveals a pressor activity of nitric oxide.

scientific article published on 5 May 2005

Platelets promote pulmonary pull of polys.

scientific article published on November 2015

Proceedings of the Food and Drug Administration's public workshop on new red blood cell product regulatory science 2016.

scientific article published on 15 December 2017

Proteomic analysis of the NOS2 interactome in human airway epithelial cells

scientific article published on 21 February 2013

Pulmonary alveolar epithelial uptake of S-nitrosothiols is regulated by L-type amino acid transporter.

scientific article published on 25 April 2008

Pulmonary vasodilator responses to RP 52891 are mediated by activation of a glibenclamide-sensitive K+ATP channel

scientific article

Randomized study of washing 40- to 42-day-stored red blood cells.

scientific article

Red blood cell phenotype fidelity following glycerol cryopreservation optimized for research purposes

scientific article published in PLoS ONE

Redox activation of intracellular calcium release channels (ryanodine receptors) in the sustained phase of hypoxia-induced pulmonary vasoconstriction

scientific article published in December 2005

Renitrosylation of banked human red blood cells improves deformability and reduces adhesivity.

scientific article

Restoration of intracellular ATP production in banked red blood cells improves inducible ATP export and suppresses RBC-endothelial adhesion

scientific article

S-Nitrosylated fetal hemoglobin in neonatal human blood

scientific article

S-nitrosoglutathione inhibits alpha1-adrenergic receptor-mediated vasoconstriction and ligand binding in pulmonary artery

scientific article published on 26 August 2005

S-nitrosohemoglobin is distinguished from other nitrosovasodilators by unique oxygen-dependent responses that support an allosteric mechanism of action

scientific article

S-nitrosothiol repletion by an inhaled gas regulates pulmonary function.

scientific article published on 24 April 2001

S-nitrosylation in health and disease ⬇️

scientific article published on April 1, 2003

Transport and peripheral bioactivities of nitrogen oxides carried by red blood cell hemoglobin: role in oxygen delivery.

scientific article published on April 2007

Transpulmonary flux of S-nitrosothiols and pulmonary vasodilation during nitric oxide inhalation: role of transport

scientific article published on 09 February 2012

Treatment-related biomarkers in pulmonary hypertension

scientific article

Treatment-related biomarkers in pulmonary hypertension patients on oral therapies

scientific article published on 19 November 2020

List of works by Tim J. McMahon

A novel inhaled organic nitrate that affects pulmonary vascular tone in a piglet model of hypoxia-induced pulmonary hypertension

Antagonists of the system L neutral amino acid transporter (LAT) promote endothelial adhesivity of human red blood cells.

Automated measurement of blood flow velocity and direction and hemoglobin oxygen saturation in the rat lung using intravital microscopy

Biomarkers in Pulmonary Vascular Disease: Gauging Response to Therapy.

Blockade of thromboxane/endoperoxide receptor-mediated responses in the pulmonary vascular bed of the cat by sulotroban

Blood Flow Regulation by S-Nitrosohemoglobin in the Physiological Oxygen Gradient

Bronchodilator S-nitrosothiol deficiency in asthmatic respiratory failure

Comparison of responses to pituitary adenylate cyclase activating peptides 38 and 27 in the pulmonary vascular bed of the cat

Concerted nitric oxide/oxygen delivery by hemoglobin

Drebrin regulates angiotensin II-induced aortic remodelling

Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock

Evolution of adverse changes in stored RBCs

Excitation-contraction coupling in airway smooth muscle

Extrapulmonary effects of inhaled nitric oxide: role of reversible S-nitrosylation of erythrocytic hemoglobin

Functional coupling of oxygen binding and vasoactivity in S-nitrosohemoglobin

HGT in the human and skin commensal Malassezia: A bacterially derived flavohemoglobin is required for NO resistance and host interaction

Hemoglobin conformation couples erythrocyte S-nitrosothiol content to O2 gradients

Impact of transfusion of autologous 7‐ versus 42‐day‐old AS‐3 red blood cells on tissue oxygenation and the microcirculation in healthy volunteers ⬇️

Impaired adenosine-5'-triphosphate release from red blood cells promotes their adhesion to endothelial cells: a mechanism of hypoxemia after transfusion.

Influence of SQ 29,548 on vasoconstrictor responses in the hindquarters vascular bed of the cat.

Influence of lemakalim on the pulmonary vascular bed of the cat

Inhaled nitric oxide therapy increases blood nitrite, nitrate, and s-nitrosohemoglobin concentrations in infants with pulmonary hypertension

Liberation of ATP secondary to hemolysis is not mutually exclusive of regulated export

Nitric oxide in the human respiratory cycle.

Nitric oxide loading reduces sickle red cell adhesion and vaso-occlusion in vivo

Oxygen regulation of tumor perfusion by S-nitrosohemoglobin reveals a pressor activity of nitric oxide.

Platelets promote pulmonary pull of polys.

Proceedings of the Food and Drug Administration's public workshop on new red blood cell product regulatory science 2016.

Proteomic analysis of the NOS2 interactome in human airway epithelial cells

Pulmonary alveolar epithelial uptake of S-nitrosothiols is regulated by L-type amino acid transporter.

Pulmonary vasodilator responses to RP 52891 are mediated by activation of a glibenclamide-sensitive K+ATP channel

Randomized study of washing 40- to 42-day-stored red blood cells.

Red blood cell phenotype fidelity following glycerol cryopreservation optimized for research purposes

Redox activation of intracellular calcium release channels (ryanodine receptors) in the sustained phase of hypoxia-induced pulmonary vasoconstriction

Renitrosylation of banked human red blood cells improves deformability and reduces adhesivity.

Restoration of intracellular ATP production in banked red blood cells improves inducible ATP export and suppresses RBC-endothelial adhesion

S-Nitrosylated fetal hemoglobin in neonatal human blood

S-nitrosoglutathione inhibits alpha1-adrenergic receptor-mediated vasoconstriction and ligand binding in pulmonary artery

S-nitrosohemoglobin is distinguished from other nitrosovasodilators by unique oxygen-dependent responses that support an allosteric mechanism of action

S-nitrosothiol repletion by an inhaled gas regulates pulmonary function.

S-nitrosylation in health and disease ⬇️

Transport and peripheral bioactivities of nitrogen oxides carried by red blood cell hemoglobin: role in oxygen delivery.

Transpulmonary flux of S-nitrosothiols and pulmonary vasodilation during nitric oxide inhalation: role of transport

Treatment-related biomarkers in pulmonary hypertension

Treatment-related biomarkers in pulmonary hypertension patients on oral therapies