List of works - Jlenia Brunetti

A New NT4 Peptide-Based Drug Delivery System for Cancer Treatment

scientific article published on 28 February 2020

A novel phage-library-selected peptide inhibits human TNF-α binding to its receptors.

scientific article

A novel tetrabranched antimicrobial peptide that neutralizes bacterial lipopolysaccharide and prevents septic shock in vivo.

scientific article published on 16 November 2009

An antimicrobial molecule mitigates signs of sepsis in vivo and eradicates infections from lung tissue

scientific article published on 20 November 2019

Analysis of opa1 isoforms expression and apoptosis regulation in autosomal dominant optic atrophy (ADOA) patients with mutations in the opa1 gene.

scientific article published on 6 March 2015

Antibacterial and Anti-Inflammatory Activity of an Antimicrobial Peptide Synthesized with D Amino Acids

scientific article published on 24 November 2020

Antimicrobial Peptide-Loaded Nanoparticles as Inhalation Therapy for Pseudomonas aeruginosa Infections

scientific article published on 17 February 2020

Coupling to a cancer-selective heparan-sulfate-targeted branched peptide can by-pass breast cancer cell resistance to methotrexate

scientific article published on 6 July 2017

Design and in vitro evaluation of branched peptide conjugates: turning nonspecific cytotoxic drugs into tumor-selective agents.

scientific article published in April 2010

Efficacy and toxicity of the antimicrobial peptide M33 produced with different counter-ions

scientific article published on 8 October 2011

Endocytosis and Trafficking of Heparan Sulfate Proteoglycans in Triple-Negative Breast Cancer Cells Unraveled with a Polycationic Peptide

scientific article published on 05 November 2020

Exploiting Free-Energy Minima to Design Novel EphA2 Protein-Protein Antagonists: From Simulation to Experiment and Return.

scientific article published on 3 May 2016

Heparan Sulfate Proteoglycans Can Promote Opposite Effects on Adhesion and Directional Migration of Different Cancer Cells

scientific article published on 07 December 2020

Heterologous Prime-Boost Combinations Highlight the Crucial Role of Adjuvant in Priming the Immune System.

scientific article

Immunomodulatory and Anti-inflammatory Activity in Vitro and in Vivo of a Novel Antimicrobial Candidate

scientific article published on 07 October 2016

In vitro and in vivo efficacy, toxicity, bio-distribution and resistance selection of a novel antibacterial drug candidate

scientific article published on 12 May 2016

Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe

scientific article

Investigations into the killing activity of an antimicrobial peptide active against extensively antibiotic-resistant K. pneumon iae and P. aeruginosa.

scientific article published on 2 June 2017

Isomerization of an antimicrobial peptide broadens antimicrobial spectrum to gram-positive bacterial pathogens

scientific article

Models of In-Vivo Bacterial Infections for the Development of Antimicrobial Peptide-based Drugs

scientific article

Molecular definition of the interaction between a tumor-specific tetrabranched peptide and LRP6 receptor

scientific article published on 17 June 2020

NMR Study of the Secondary Structure and Biopharmaceutical Formulation of an Active Branched Antimicrobial Peptide

scientific article published on 25 November 2019

Nanoparticles exposing neurotensin tumor-specific drivers.

scientific article published on 25 February 2013

Near-infrared quantum dots labelled with a tumor selective tetrabranched peptide for in vivo imaging.

scientific article published on 3 March 2018

Neurotensin branched peptide as a tumor-targeting agent for human bladder cancer.

scientific article published on 23 April 2015

Oxidative stress-induced apoptosis in peripheral blood lymphocytes from patients with POLG-related disorders.

scientific article published on 25 July 2016

Site-specific pegylation of an antimicrobial peptide increases resistance to Pseudomonas aeruginosa elastase

scientific article published on 08 February 2014

Solubility improvement of an anthrax toxin peptide inhibitor by rational amino acid randomization.

scientific article

Stable peptide inhibitors prevent binding of lethal and oedema factors to protective antigen and neutralize anthrax toxin in vivo

scientific article

Synergistic activity profile of an antimicrobial peptide against multidrug-resistant and extensively drug-resistant strains of Gram-negative bacterial pathogens

scientific article published on 8 February 2017

Synthesis and biological activity of stable branched neurotensin peptides for tumor targeting

scientific article published on 31 August 2007

Target-selective drug delivery through liposomes labeled with oligobranched neurotensin peptides

scientific article published on 02 March 2011

The GAG-specific branched peptide NT4 reduces angiogenesis and invasiveness of tumor cells.

scientific article

The proteome speciation of an immortalized cystic fibrosis cell line: New perspectives on the pathophysiology of the disease.

scientific article published on 29 September 2017

Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug

scientific article

Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity

scientific article published on 18 September 2019

List of works by Jlenia Brunetti

A New NT4 Peptide-Based Drug Delivery System for Cancer Treatment

A novel phage-library-selected peptide inhibits human TNF-α binding to its receptors.

A novel tetrabranched antimicrobial peptide that neutralizes bacterial lipopolysaccharide and prevents septic shock in vivo.

An antimicrobial molecule mitigates signs of sepsis in vivo and eradicates infections from lung tissue

Analysis of opa1 isoforms expression and apoptosis regulation in autosomal dominant optic atrophy (ADOA) patients with mutations in the opa1 gene.

Antibacterial and Anti-Inflammatory Activity of an Antimicrobial Peptide Synthesized with D Amino Acids

Antimicrobial Peptide-Loaded Nanoparticles as Inhalation Therapy for Pseudomonas aeruginosa Infections

Coupling to a cancer-selective heparan-sulfate-targeted branched peptide can by-pass breast cancer cell resistance to methotrexate

Design and in vitro evaluation of branched peptide conjugates: turning nonspecific cytotoxic drugs into tumor-selective agents.

Efficacy and toxicity of the antimicrobial peptide M33 produced with different counter-ions

Endocytosis and Trafficking of Heparan Sulfate Proteoglycans in Triple-Negative Breast Cancer Cells Unraveled with a Polycationic Peptide

Exploiting Free-Energy Minima to Design Novel EphA2 Protein-Protein Antagonists: From Simulation to Experiment and Return.

Heparan Sulfate Proteoglycans Can Promote Opposite Effects on Adhesion and Directional Migration of Different Cancer Cells

Heterologous Prime-Boost Combinations Highlight the Crucial Role of Adjuvant in Priming the Immune System.

Immunomodulatory and Anti-inflammatory Activity in Vitro and in Vivo of a Novel Antimicrobial Candidate

In vitro and in vivo efficacy, toxicity, bio-distribution and resistance selection of a novel antibacterial drug candidate

Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe

Investigations into the killing activity of an antimicrobial peptide active against extensively antibiotic-resistant K. pneumon iae and P. aeruginosa.

Isomerization of an antimicrobial peptide broadens antimicrobial spectrum to gram-positive bacterial pathogens

Models of In-Vivo Bacterial Infections for the Development of Antimicrobial Peptide-based Drugs

Molecular definition of the interaction between a tumor-specific tetrabranched peptide and LRP6 receptor

NMR Study of the Secondary Structure and Biopharmaceutical Formulation of an Active Branched Antimicrobial Peptide

Nanoparticles exposing neurotensin tumor-specific drivers.

Near-infrared quantum dots labelled with a tumor selective tetrabranched peptide for in vivo imaging.

Neurotensin branched peptide as a tumor-targeting agent for human bladder cancer.

Oxidative stress-induced apoptosis in peripheral blood lymphocytes from patients with POLG-related disorders.

Site-specific pegylation of an antimicrobial peptide increases resistance to Pseudomonas aeruginosa elastase

Solubility improvement of an anthrax toxin peptide inhibitor by rational amino acid randomization.

Stable peptide inhibitors prevent binding of lethal and oedema factors to protective antigen and neutralize anthrax toxin in vivo

Synergistic activity profile of an antimicrobial peptide against multidrug-resistant and extensively drug-resistant strains of Gram-negative bacterial pathogens

Synthesis and biological activity of stable branched neurotensin peptides for tumor targeting

Target-selective drug delivery through liposomes labeled with oligobranched neurotensin peptides

The GAG-specific branched peptide NT4 reduces angiogenesis and invasiveness of tumor cells.

The proteome speciation of an immortalized cystic fibrosis cell line: New perspectives on the pathophysiology of the disease.

Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug

Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity