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List of works by Keng Po Lai

A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response.

scientific article published on 15 May 2012

A positive role for c-Abl in Atm and Atr activation in DNA damage response.

scientific article

Adverse health effects and stresses on offspring due to paternal exposure to harmful substances

scientific article published on 20 October 2022

Bifunctional modulating effects of an indigo dimer (bisindigotin) to CYP1A1 induction in H4IIE cells

scientific journal article

Bioinformatics and <i>in-silico</i> findings reveal medical features and pharmacological targets of biochanin A against colorectal cancer and COVID-19

scientific article published on 01 December 2021

Bisphenol A alters gut microbiome: Comparative metagenomics analysis

scientific article

Changes in endogenous Zn and Cu distribution in different cytosolic protein fractions in mouse liver after administration of a single sublethal dose of CdCl(2)

scientific article published on 01 November 2000

Clinical characterization and therapeutic targets of vitamin A in patients with hepatocholangiocarcinoma and coronavirus disease

scientific article published on 27 June 2021

Comparative Analysis of PFOS and PFOA Toxicity on Sertoli Cells

scientific article published on 06 March 2020

Comparative transcriptomic characterization of a new mib mutant allele, mibnn2002, in zebrafish.

scientific article published on 7 November 2017

Data for transcriptomic and iTRAQ proteomic analysis of Anguilla japonica gills in response to osmotic stress.

scientific article

Deep sequencing of small RNA transcriptome reveals novel non-coding RNAs in hepatocellular carcinoma

scientific article published on 29 January 2013

Deubiquitinase Usp18 prevents cellular apoptosis from oxidative stress in liver cells

scientific article

Developmental toxicity of the common UV filter, benophenone-2, in zebrafish embryos.

scientific article published on 3 September 2016

Dietary Exposure to the Environmental Chemical, PFOS on the Diversity of Gut Microbiota, Associated With the Development of Metabolic Syndrome

article

Differential responses of female and male brains to hypoxia in the marine medaka Oryzias melastigma

scientific article published on 30 December 2015

Dioxin-like components in human breast milk collected from Hong Kong and Guangzhou.

scientific article published on September 2004

Discovery and functional characterization of novel miRNAs in the marine medaka Oryzias melastigma

scientific article

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the differentiation of embryonic stem cells towards pancreatic lineage and pancreatic beta cell function

scientific article published on 10 June 2019

Effects of TCDD in modulating the expression of Sertoli cell secretory products and markers for cell-cell interaction

scientific article published in January 2005

Effects of in Utero PFOS Exposure on Transcriptome, Lipidome, and Function of Mouse Testis

scientific article published on 27 June 2017

Fatty liver disease induced by perfluorooctane sulfonate: Novel insight from transcriptome analysis.

scientific article published on 09 June 2016

GEF-H1 over-expression in hepatocellular carcinoma promotes cell motility via activation of RhoA signalling

scientific article published on 28 September 2012

Hepatic metabolism gene expression and gut microbes in offspring, subjected to in-utero PFOS exposure and postnatal diet challenges

scientific article published in 2022

Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation.

scientific article

Hypoxia Causes Transgenerational Impairment of Ovarian Development and Hatching Success in Fish

scientific article published on 22 March 2019

Hypoxia alters steroidogenesis in female marine medaka through miRNAs regulation.

scientific article published on 24 December 2015

Hypoxia alters testicular functions of marine medaka through microRNAs regulation.

scientific article

Hypoxia causes transgenerational impairments in reproduction of fish

scientific article published on 04 July 2016

Hypoxia induces miR-210, leading to anti-apoptosis in ovarian follicular cells of marine medaka Oryzias melastigma.

scientific article published on 05 June 2015

Hypoxia-inducible factor-1-mediated activation of stanniocalcin-1 in human cancer cells.

scientific article published on 18 August 2005

Identification and characterization of the hypoxia-responsive element in human stanniocalcin-1 gene.

scientific article

Identification and expression profiling of microRNAs in the brain, liver and gonads of marine medaka (Oryzias melastigma) and in response to hypoxia

scientific article

Identification of immune-related genes in gill cells of Japanese eels (Anguilla japonica) in adaptation to water salinity changes.

scientific article published on 18 December 2017

Induction of stanniocalcin-1 expression in apoptotic human nasopharyngeal cancer cells by p53.

scientific article published on 22 March 2007

Inhibition of CYP450scc expression in dioxin-exposed rat Leydig cells

scientific article published in June 2005

Medaka osmotic stress transcription factor 1b (Ostf1b/TSC22D3-2) triggers hyperosmotic responses of different ion transporters in medaka gill and human embryonic kidney cells via the JNK signalling pathway.

scientific article

Metabolomic analysis reveals metabolic alterations of human peripheral blood lymphocytes by perfluorooctanoic acid

scientific article published on 07 September 2019

Modulation of AhR-mediated CYP1A1 mRNA and EROD activities by 17beta-estradiol and dexamethasone in TCDD-induced H411E cells.

scientific article published on 22 December 2003

Modulation of ion transporter expression in gill mitochondrion-rich cells of eels acclimated to low-Na(+) or-Cl(-) freshwater.

scientific article

Overexpression of ZFX confers self-renewal and chemoresistance properties in hepatocellular carcinoma

scientific article published on 11 March 2014

Pathogenesis of POLR1C-dependent Type 3 Treacher Collins Syndrome revealed by a zebrafish model

scientific article published on 10 March 2016

Role of Deubiquitinases in Human Cancers: Potential Targeted Therapy

scientific article published on 06 April 2020

S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response

scientific journal article

TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration

scientific article published on 17 May 2021

Tissue-specific transcriptome assemblies of the marine medaka Oryzias melastigma and comparative analysis with the freshwater medaka Oryzias latipes

scientific article

Transcriptome sequencing of Chinese and Caucasian population identifies ethnic-associated differential transcript abundance of heterogeneous nuclear ribonucleoprotein K (hnRNPK).

scientific article

Transcriptome sequencing reveals prenatal PFOS exposure on liver disorders.

scientific article published on 25 January 2017

Transcriptomic alterations in Daphnia magna embryos from mothers exposed to hypoxia.

scientific article published on 24 June 2016

Transcriptomic analysis reveals specific osmoregulatory adaptive responses in gill mitochondria-rich cells and pavement cells of the Japanese eel.

scientific article published on 18 December 2015

Transcriptomic analysis reveals transgenerational effect of hypoxia on the neural control of testicular functions

scientific article published on 16 December 2017

Transcriptomic and Functional Analyses on the Effects of Dioxin on Insulin Secretion of Pancreatic Islets and β-Cells.

scientific article

Transcriptomic and methylomic analysis reveal the toxicological effect of 2,3,7,8-Tetrachlorodibenzodioxin on human embryonic stem cell

scientific article published on 10 May 2018

Transcriptomic responses of corpuscle of Stannius gland of Japanese eels (Anguilla japonica) to changes in water salinity

scientific article published on 24 April 2015

Transcriptomic responses of marine medaka's ovary to hypoxia

scientific article published on 28 June 2016

Transgenerational bone toxicity in F3 medaka (Oryzias latipes) induced by ancestral benzo[a]pyrene exposure: Cellular and transcriptomic insights

scientific article published in 2023

iTRAQ-based quantitative proteomic analysis reveals acute hypo-osmotic responsive proteins in the gills of the Japanese eel (Anguilla japonica).

scientific article published on 3 February 2014