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List of works by Chau Ling Tham

1 H‐NMR metabolomics for evaluating the protective effect of Clinacanthus nutans (Burm. f) Lindau water extract against nitric oxide production in LPS‐IFN‐ γ activated RAW 264.7 macrophages

scientific article published on 05 September 2018

1H-NMR-based metabolomics to investigate the effects of Phoenix dactylifera seed extracts in LPS-IFN-γ-induced RAW 264.7 cells

scientific article published on 16 July 2019

A Comprehensive Review on Phytochemistry and Pharmacological Activities of (Burm.f.) Lindau

scientific article published on 04 July 2018

A Review of Malaysian Herbal Plants and Their Active Constituents with Potential Therapeutic Applications in Sepsis

scientific article published on 28 October 2020

A geranyl acetophenone targeting cysteinyl leukotriene synthesis prevents allergic airway inflammation in ovalbumin-sensitized mice

scientific article published on 12 January 2012

A synthetic curcuminoid derivative inhibits nitric oxide and proinflammatory cytokine synthesis.

scientific article

A synthetic hydroxypropenone inhibits nitric oxide, prostaglandin E2, and proinflammatory cytokine synthesis.

scientific article published in September 2010

An orally active geranyl acetophenone attenuates airway remodeling in a murine model of chronic asthma

scientific article published on 12 January 2017

Anti-allergic activity of 2,4,6-trihydroxy-3-geranylacetophenone (tHGA) via attenuation of IgE-mediated mast cell activation and inhibition of passive systemic anaphylaxis.

scientific article published on 3 February 2017

Barrier protective effects of 2,4,6-trihydroxy-3-geranyl acetophenone on lipopolysaccharides-stimulated inflammatory responses in human umbilical vein endothelial cells.

scientific article published on 9 July 2016

Blockade of Eosinophil-Induced Bronchial Epithelial-Mesenchymal Transition with a Geranyl Acetophenone in a Coculture Model

scientific article published on 16 November 2017

Crosstalk Between Signaling Pathways Involved in the Regulation of Airway Smooth Muscle Cell Hyperplasia

scientific article published on 09 October 2019

Development and validation of a bioanalytical method for quantification of 2,6-bis-(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) in rat plasma

scientific article published on 07 December 2012

Effects of 3-(2-Hydroxyphenyl)-1-(5-methyl-furan-2-y-l) propenone (HMP) upon signalling pathways of lipopolysaccharide-induced iNOS synthesis in RAW 264.7 cells.

scientific article published on 28 October 2010

Flavonoid combinations cause synergistic inhibition of proinflammatory mediator secretion from lipopolysaccharide-induced RAW 264.7 cells.

scientific article published on 11 March 2010

Hematological, Biochemical, Histopathological and ¹H-NMR Metabolomics Application in Acute Toxicity Evaluation of Water Leaf Extract

article

Identification of Soluble Mediators in IgG-Mediated Anaphylaxis via Fcγ Receptor: A Meta-Analysis

scientific article published on 12 February 2019

In silico studies, nitric oxide, and cholinesterases inhibition activities of pyrazole and pyrazoline analogs of diarylpentanoids

scientific article published on 04 September 2020

Inhibition of Epithelial CC-Family Chemokine Synthesis by the Synthetic Chalcone DMPF-1 via Disruption of NF-κB Nuclear Translocation and Suppression of Experimental Asthma in Mice

scientific article

Kaempferol and Chrysin Synergies to Improve Septic Mice Survival.

scientific article published on 6 January 2017

LAT is essential for the mast cell stabilising effect of tHGA in IgE-mediated mast cell activation

scientific article published on 13 August 2017

Major Bioactive Compounds in Essential Oils Extracted From the Rhizomes of Zingiber zerumbet (L) Smith: A Mini-Review on the Anti-allergic and Immunomodulatory Properties.

scientific article

Mast cell stabilizing effect of a geranyl acetophenone in dengue virus infection using in vitro model of DENV3-induced RBL-2H3 cells.

scientific article

Meta-analysis of biomarkers for severe dengue infections.

scientific article published on 15 September 2017

NMR metabolomics for evaluating passage number and harvesting effects on mammalian cell metabolome

scientific article published on 07 April 2019

Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives

scientific article published on 30 May 2015

Pharmacokinetics and Metabolism of Liposome-Encapsulated 2,4,6-Trihydroxygeranylacetophenone in Rats Using High-Resolution Orbitrap Liquid Chromatography Mass Spectrometry

scientific article published on 06 July 2020

Plasma and urine metabolite profiling reveals the protective effect of Clinacanthus nutans in an ovalbumin-induced anaphylaxis model: 1 H-NMR metabolomics approach

scientific article published on 22 June 2018

Synthesis and QSAR analysis of chalcone derivatives as nitric oxide inhibitory agent

Synthesis and evaluation of DPPH and anti-inflammatory activities of 2,6-bisbenzylidenecyclohexanone and pyrazoline derivatives

Synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents

scientific article published on 9 October 2014

The Molecular Targets and Anti-Invasive Effects of 2,6-bis-(4-hydroxyl-3methoxybenzylidine) cyclohexanone or BHMC in MDA-MB-231 Human Breast Cancer Cells.

scientific article published on 10 April 2018

The Protective Effects of a Synthetic Geranyl Acetophenone in a Cellular Model of TNF-α-Induced Pulmonary Epithelial Barrier Dysfunction.

scientific article

The differential effects of commercial specialized media on cell growth and transforming growth factor beta 1-induced epithelial-mesenchymal transition in bronchial epithelial cells

scientific article published on 11 April 2020

The effects of a synthetic curcuminoid analogue, 2,6-bis-(4-hydroxyl-3-methoxybenzylidine)cyclohexanone on proinflammatory signaling pathways and CLP-induced lethal sepsis in mice

scientific article published on 30 November 2010

The geranyl acetophenone tHGA attenuates human bronchial smooth muscle proliferation via inhibition of AKT phosphorylation

scientific article published in Scientific Reports

The synthetic curcuminoid BHMC restores endotoxin-stimulated HUVEC dysfunction:Specific disruption on enzymatic activity of p38 MAPK.

scientific article published on 3 January 2015

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