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List of works by Jan Pravsgaard Christensen

A 'Furry-Tale' of Zika Virus Infection: What Have We Learned from Animal Models?

scientific article published on 06 January 2019

A Liposome-Based Adjuvant Containing Two Delivery Systems with the Ability to Induce Mucosal Immunoglobulin A Following a Parenteral Immunization

scientific article published on 18 January 2019

A New In Vivo Model to Study Protective Immunity to Zika Virus Infection in Mice With Intact Type I Interferon Signaling

scientific article published on 22 March 2018

A Systematic, Unbiased Mapping of CD8+ and CD4+ T Cell Epitopes in Yellow Fever Vaccinees

scientific article published on 31 August 2020

A Vaccine Displaying a Trimeric Influenza-A HA Stem Protein on Capsid-Like Particles Elicits Potent and Long-Lasting Protection in Mice

scientific article published on 15 July 2020

A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog

A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin

scientific article published on 12 October 2012

A systematic, unbiased mapping of CD8+ and CD4+ T cell epitopes in Yellow Fever vaccinees

scientific article published on 02 April 2020

Accessing complexity: the dynamics of virus-specific T cell responses.

scientific article

Adaptive Immunity against Streptococcus pyogenes in Adults Involves Increased IFN-γ and IgG3 Responses Compared with Children

scientific article published on 10 July 2015

Adaptive immune responses to booster vaccination against yellow fever virus are much reduced compared to those after primary vaccination

scientific article (publication date: 6 April 2017)

Adenoviral vaccination combined with CD40 stimulation and CTLA-4 blockage can lead to complete tumor regression in a murine melanoma model

article

Adenovirus-based vaccine against Listeria monocytogenes: extending the concept of invariant chain linkage

scientific article published on 16 September 2013

Agonistic anti-CD40 antibody profoundly suppresses the immune response to infection with lymphocytic choriomeningitis virus

scientific article published in February 2007

Alpha 4 integrin directs virus-activated CD8+ T cells to sites of infection

scientific article

Analysis of adenovirus-induced immunity to infection with Listeria monocytogenes: Fading protection coincides with declining CD8 T cell numbers and phenotypic changes.

scientific article

Application of image cytometry to characterize heterologous lipid flippases in yeast

scientific article published on 6 June 2016

Broadening CD4+ and CD8+ T Cell Responses against Hepatitis C Virus by Vaccination with NS3 Overlapping Peptide Panels in Cross-Priming Liposomes

scientific article published on 26 April 2017

CD4 and CD8 T cell responses to the M. tuberculosis Ag85B-TB10.4 promoted by adjuvanted subunit, adenovector or heterologous prime boost vaccination

scientific article

CD40 ligand is pivotal to efficient control of virus replication in mice infected with lymphocytic choriomeningitis virus.

scientific article published in November 1998

CD8+ T cells complement antibodies in protecting against yellow fever virus

scientific article

CXCL10 is the key ligand for CXCR3 on CD8+ effector T cells involved in immune surveillance of the lymphocytic choriomeningitis virus-infected central nervous system

scientific article published in April 2006

CXCR3 directs antigen-specific effector CD4+ T cell migration to the lung during parainfluenza virus infection

scientific article published on 04 September 2009

Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

scientific article published on 12 January 2021

Characterization of virus-primed CD8+ T cells with a type 1 cytokine profile

scientific article published in September 1996

Chemokine Expression in Murine RPE/Choroid in Response to Systemic Viral Infection and Elevated Levels of Circulating Interferon-γ

scientific article published on 01 January 2019

Circulating intercellular adhesion molecule-1 (ICAM-1) as an early and sensitive marker for virus-induced T cell activation

scientific article

Co-expression of tumor antigen and interleukin-2 from an adenoviral vector augments the efficiency of therapeutic tumor vaccination

scientific article published on 15 July 2014

Combined local and systemic immunization is essential for durable T-cell mediated heterosubtypic immunity against influenza A virus

scientific article published on February 2016

Comparing adjuvanted H28 and modified vaccinia virus ankara expressingH28 in a mouse and a non-human primate tuberculosis model

scientific article

Comparison of vaccine-induced effector CD8 T cell responses directed against self- and non-self-tumor antigens: implications for cancer immunotherapy

scientific article published on 9 September 2013

Compromised virus control and augmented perforin-mediated immunopathology in IFN-gamma-deficient mice infected with lymphocytic choriomeningitis virus

scientific article published in December 1999

Cooperation of B cells and T cells is required for survival of mice infected with vesicular stomatitis virus

scientific article published in November 1997

Cryopreservation of peripheral blood mononuclear cells for use in proliferation assays: First step towards potency assays

scientific article published on 10 October 2020

Cytokine production by virus-specific CD8(+) T cells varies with activation state and localization, but not with TCR avidity

scientific article published in June 2004

Cytotoxic CD8+ T cells in cancer and cancer immunotherapy

scientific article published on 15 September 2020

DNA fusion gene vaccines.

scientific article published on February 2010

Deficient CD4+ T cell priming and regression of CD8+ T cell functionality in virus-infected mice lacking a normal B cell compartment

scientific article published in November 2003

Delayed contraction of the CD8+ T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycin

scientific journal article

Depletion of CD4+ T cells precipitates immunopathology in immunodeficient mice infected with a noncytocidal virus

scientific article published in March 2001

Detection of local inflammation induced by repeated exposure to contact allergens by use of IVIS SpectrumCT analyses

Difference in TB10.4 T-cell epitope recognition following immunization with recombinant TB10.4, BCG or infection with Mycobacterium tuberculosis

article

Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery

scientific article

Diminished primary and secondary influenza virus-specific CD8(+) T-cell responses in CD4-depleted Ig(-/-) mice. ⬇️

scientific article

EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies

scientific article published on 21 December 2016

Early life vaccination: Generation of adult-quality memory CD8+ T cells in infant mice using non-replicating adenoviral vectors.

scientific article published on 08 December 2016

Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice

scientific article

Effector CD8 T Cell-Dependent Zika Virus Control in the CNS: A Matter of Time and Numbers

scientific article published on 18 August 2020

Efficient Control of Zika Virus Infection Induced by a Non-Replicating Adenovector Encoding Zika Virus NS1/NS2 Antigens Fused to the MHC Class II-Associated Invariant Chain

scientific article published in 2021

Efficient T-cell surveillance of the CNS requires expression of the CXC chemokine receptor 3.

scientific article published in May 2004

Enhanced and Sustained CD8+ T Cell Responses with an Adenoviral Vector-Based Hepatitis C Virus Vaccine Encoding NS3 Linked to the MHC Class II Chaperone Protein Invariant Chain ⬇️

scientific article published on January 21, 2011

Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient mice

scientific article published in October 1996

Expression and functional importance of collagen-binding integrins, alpha 1 beta 1 and alpha 2 beta 1, on virus-activated T cells

scientific article published in September 2003

Expression of type 3 complement receptor on activated CD8+ T cells facilitates homing to inflammatory sites

scientific article published on 01 September 1994

Fulminant lymphocytic choriomeningitis virus-induced inflammation of the CNS involves a cytokine-chemokine-cytokine-chemokine cascade

scientific article published in January 2009

Fusion of a viral antigen to invariant chain leads to augmented T-cell immunity and improved protection in gene-gun DNA-vaccinated mice

article

GPR183 Is Dispensable for B1 Cell Accumulation and Function, but Affects B2 Cell Abundance, in the Omentum and Peritoneal Cavity

scientific article published on 31 January 2022

High numbers of IL-2-producing CD8+ T cells during viral infection: correlation with stable memory development

scientific article published in September 2002

Host factors influencing viral persistence.

scientific article

IFNγ and perforin cooperate to control infection and prevent fatal pathology during persistent gammaherpesvirus infection in mice.

scientific article published on June 2014

Identifying protective Streptococcus pyogenes vaccine antigens recognized by both B and T cells in human adults and children

scientific article published on 25 February 2016

Immune cells from SR/CR mice induce the regression of established tumors in BALB/c and C57BL/6 mice

scientific article

Immunogenicity of HLA Class I and II Double Restricted Influenza A-Derived Peptides

scientific article

Immunological control of a murine gammaherpesvirus independent of CD8+ T cells

scientific article published on 01 February 1999

Impaired virus control and severe CD8+ T-cell-mediated immunopathology in chimeric mice deficient in gamma interferon receptor expression on both parenchymal and hematopoietic cells

scientific article published on August 2005

Increased immunogenicity and protective efficacy of influenza M2e fused to a tetramerizing protein

scientific article

JNK1, but not JNK2, is required in two mechanistically distinct models of inflammatory arthritis

scientific article published on 11 August 2011

Local Antigen Encounter Is Essential for Establishing Persistent CD8 T-Cell Memory in the CNS

scientific article published on 04 March 2019

Local Th17/IgA immunity correlate with protection against intranasal infection with Streptococcus pyogenes

scientific article

Lymphocytic choriomeningitis virus infection is associated with long-standing perturbation of LFA-1 expression on CD8+ T cells

scientific article published in July 1995

MEK kinase 1 activity is required for definitive erythropoiesis in the mouse fetal liver.

scientific article published on 4 August 2005

MEK kinase 1 is a negative regulator of virus-specific CD8(+) T cells

scientific article published on August 2006

MHC Class II-Associated Invariant Chain Linkage of Antigen Dramatically Improves Cell-Mediated Immunity Induced by Adenovirus Vaccines

article published in 2008

MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans

scientific article published on 01 June 2020

Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity

scientific article

Mucosal Vaccination with Heterologous Viral Vectored Vaccine Targeting Subdominant SIV Accessory Antigens Strongly Inhibits Early Viral Replication.

scientific article

Mucosal immunization with recombinant adenoviral vectors expressing murine gammaherpesvirus-68 genes M2 and M3 can reduce latent viral load

article

Non-MHC genes influence virus clearance through regulation of the antiviral T-cell response: correlation between virus clearance and Tc and Td activity in segregating backcross progeny

scientific article published in January 1994

Opposing effects of CXCR3 and CCR5 deficiency on CD8+ T cell-mediated inflammation in the central nervous system of virus-infected mice

scientific article

PB1 as a potential target for increasing the breadth of T-cell mediated immunity to Influenza A.

scientific article published on 07 October 2016

Perforin and Fas in murine gammaherpesvirus-specific CD8(+) T cell control and morbidity

scientific article

Perforin and IFN-gamma do not significantly regulate the virus-specific CD8+ T cell response in the absence of antiviral effector activity

scientific article published in May 2004

Perforin-deficient CD8+ T cells mediate fatal lymphocytic choriomeningitis despite impaired cytokine production

scientific article published in February 2006

Pre-existing vector immunity does not prevent replication deficient adenovirus from inducing efficient CD8 T-cell memory and recall responses

scientific article (publication date: 2012)

Priming of CD8 T cells by adenoviral vectors is critically dependent on B7 and dendritic cells but only partially dependent on CD28 ligation on CD8 T cells

scientific article published on 20 June 2014

Protein energy malnutrition during vaccination has limited influence on vaccine efficacy but abolishes immunity if administered during Mycobacterium tuberculosis infection

scientific article

Qualitative and quantitative analysis of adenovirus type 5 vector-induced memory CD8 T cells: not as bad as their reputation.

scientific article published on 27 March 2013

Quality of the transgene-specific CD8+ T cell response induced by adenoviral vector immunization is critically influenced by virus dose and route of vaccination

scientific article published on 8 March 2010

Quantification of B16 melanoma cells in lungs using triplex Q-PCR--a new approach to evaluate melanoma cell metastasis and tumor control.

scientific article published on 31 January 2014

Rapid and sustained CD4+ T-cell-independent immunity from adenovirus-encoded vaccine antigens

scientific article published on 01 June 2007

Regulation of T cell migration during viral infection: role of adhesion molecules and chemokines

scientific article

Requirement for CD40 ligand, CD4(+) T cells, and B cells in an infectious mononucleosis-like syndrome

scientific article

Role of CD28 co-stimulation in generation and maintenance of virus-specific T cells

scientific article published in July 2002

Role of interferon-gamma in the pathogenesis of LCMV-induced meningitis: unimpaired leucocyte recruitment, but deficient macrophage activation in interferon-gamma knock-out mice

scientific article

Role of macrophage inflammatory protein-1alpha in T-cell-mediated immunity to viral infection

scientific article published on November 2003

Role of very late antigen-1 in T-cell-mediated immunity to systemic viral infection

scientific article published in April 2006

Seasonal Influenza Split Vaccines Confer Partial Cross-Protection against Heterologous Influenza Virus in Ferrets When Combined with the CAF01 Adjuvant

scientific article published in January 2017

Sensitization to Lipopolysaccharide in Mice with Asymptomatic Viral Infection: Role of T Cell‐Dependent Production of Interferon–γ

article

Single-cell heterogeneity in Sézary syndrome

scientific article published on 01 August 2018

Single-epitope DNA vaccination prevents exhaustion and facilitates a broad antiviral CD8+ T cell response during chronic viral infection

scientific article published in November 2004

Suppressors of cytokine signaling 1 and 3 are upregulated in brain resident cells in response to virus-induced inflammation of the central nervous system via at least two distinctive pathways

scientific article

T-Cell Responsiveness to LCMV Segregates as a Single Locus in Crosses between BALB/cA and C.B-17 Mice. Evidence for Regulation by a Gene Outside the Igh Region

article

T-cell intrinsic expression of MyD88 is required for sustained expansion of the virus-specific CD8+ T-cell population in LCMV-infected mice

scientific article published in February 2009

TCR down-regulation controls virus-specific CD8+ T cell responses

scientific article published in December 2008

Targeting of non-dominant antigens as a vaccine strategy to broaden T-cell responses during chronic viral infection

scientific article

The availability of a functional tumor targeting T-cell repertoire determines the anti-tumor efficiency of combination therapy with anti-CTLA-4 and anti-4-1BB antibodies

scientific article

The cementless AGC 2000 knee prosthesis: 20-year results in a consecutive series

scientific article published on 01 April 2009

The importance of lytic and nonlytic immune responses in viral infections

article

The murine gammaherpesvirus-68 chemokine-binding protein M3 inhibits experimental autoimmune encephalomyelitis

scientific article published on July 2010

The role of CC chemokine receptor 5 in antiviral immunity

scientific article published on 01 February 2002

The role of CD4+ T cells in cell-mediated immunity to LCMV: studies in MHC class I and class II deficient mice

scientific article published in October 1994

The role of CD80/CD86 in generation and maintenance of functional virus-specific CD8+ T cells in mice infected with lymphocytic choriomeningitis virus

scientific article

Turnover of T cells in murine gammaherpesvirus 68-infected mice

scientific article

Vaccination against Lymphocytic Choriomeningitis Virus Infection in MHC Class II-Deficient Mice ⬇️

scientific article published on February 28, 2011

Vaccination with Replication Deficient Adenovectors Encoding YF-17D Antigens Induces Long-Lasting Protection from Severe Yellow Fever Virus Infection in Mice

scientific article (publication date: February 2016)

Vaccination with an adenoviral vector encoding the tumor antigen directly linked to invariant chain induces potent CD4+T-cell-independent CD8+T-cell-mediated tumor control

scholarly article by Maria R. Sorensen et al published October 2009 in European Journal of Immunology

Vaccine Targeting of Subdominant CD8+ T Cell Epitopes Increases the Breadth of the T Cell Response upon Viral Challenge, but May Impair Immediate Virus Control

scientific article

Vesicular stomatitis virus infection promotes immune evasion by preventing NKG2D-ligand surface expression

scientific article

Virus-activated T cells regulate expression of adhesion molecules on endothelial cells in sites of infection

scientific article

Virus-induced T cell activation and the inflammatory response.

scientific article published on January 1998

Virus-induced polyclonal T cell activation is followed by apoptosis: partitioning of CD8+ T cells based on alpha 4 integrin expression

scientific article published in May 1996

[Avian influenza and perspectives on vaccination against pandemic influenza].

scientific article

[HPV vaccination – should/should not?] ⬇️

scientific article published on 01 August 2015

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